An aerial view of a city with a river, a bridge, and a large construction site.

Seacoast Region Vacations from $452

Book a Hotel + Flight or Car together to unlock savings

Your Seacoast Region Vacation

Book a vacation package to Seacoast Region and make planning your adventure easy. With the finer details taken care of before you leave, you can focus on enjoying every second in this wonderful destination. With so many things to explore on a trip to Seacoast Region, it can be hard to know where to start. Kick off your journey in Portsmouth at Water Country and Kittery Premium Outlets — two popular attractions here. Another city worthy of a spot on your itinerary is Rochester. Be sure not to miss The Children's Museum of New Hampshire and Rochester Opera House. If you're ready to stop dreaming and start traveling, Expedia will help turn your Seacoast Region vacation into a reality.

The Latest Seacoast Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Dec 17 - Dec 21
Boston Lodge and Suites + Flight
Dorchester
4 nights
4.0 star property
8.4/10 - Very good (194 reviews)
"The accommodation was great and spacious enough for a large group. There were five of us, and it was perfect for our needs. The apartment was clean, and everything we needed was provided, including towels, soap, dishwasher detergent, and more. We turned on the oven to make dinner, but we were unable to turn it off because the buttons weren’t working. We called for assistance and received a response very quickly, which made us feel supported and taken care of. Overall, we had a great stay! The..."
Reviewed October 17, 2026
Roundtrip • Atlanta (ATL) - Boston (BOS)
ATL - BOS • Nonstop BOS - ATL • Nonstop
~~$1,218~~
$452
per traveler
found 1 day ago
Boston Lodge and Suites
Dec 18 - Dec 22
Boston Harbor Hotel + Flight
North End
4 nights
5.0 star property
9.8/10 - Exceptional (1,001 reviews)
Roundtrip • Atlanta (ATL) - Boston (BOS)
ATL - BOS • Nonstop BOS - ATL • Nonstop
~~$1,944~~
$1,163
per traveler
found 1 day ago
Boston Harbor Hotel
Dec 13 - Dec 19
Four Seasons Hotel Boston + Flight
Bay Village
6 nights
5.0 star property
9.4/10 - Exceptional (499 reviews)
Roundtrip • Miami (MIA) - Boston (BOS)
FLL - BOS • Nonstop BOS - MIA • 1 stop
Save 100% on your flight
~~$3,423~~
$2,140
per traveler
found 1 day ago
Four Seasons Hotel Boston
Jan 15 - Jan 19
Riverhouse by Weekender (Formerly Jack Daniels Inn) + Flight
Peterborough
4 nights
2.5 star property
9.2/10 - Wonderful (483 reviews)
"5"
Reviewed November 12, 2026
Roundtrip • Miami (MIA) - Manchester (MHT)
MIA - BOS • Nonstop BOS - MIA • Nonstop
~~$721~~
$469
per traveler
found 1 day ago
Riverhouse by Weekender (Formerly Jack Daniels Inn)
Jan 28 - Feb 1
The Onset Beach Compound-Cape Cod Beach Resort & Oceanic Habitat + Flight
East Wareham
4 nights
3.0 star property
10/10 - Exceptional (11 reviews)
"We had a great experience staying in the crab house. The cottage was well maintained and had everything we needed to enjoy our stay. The staff was friendly, helpful, and genuinely care. Ken was fantastic, you can really tell he cares about ensuring guests have a great experience. 10/10 experience, would recommend this spot to anyone looking for a great stay on the cape."
Reviewed July 27, 2026
Roundtrip • Miami (MIA) - Boston (BOS)
FLL - BOS • Nonstop BOS - MIA • Nonstop
~~$1,522~~
$1,055
per traveler
found 1 day ago
The Onset Beach Compound-Cape Cod Beach Resort & Oceanic Habitat

Discover the most popular places to visit in Seacoast Region

A public square with a water fountain, benches, and a stop sign.

Market Square

9.2/10 (1,088 reviews)

You can learn about the history of Portsmouth with a visit to Market Square. While in this family-friendly area, you can savor the top-notch restaurants.

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