A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Find 2 Star Hotels in Defiance, MO from $65

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Our top choices for Defiance 2-star hotels

1. Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn and Suites by Wyndham St. Louis/Westport Plaza
2.5 star property
Westport
4.6 out of 10, (1,004 reviews)
"The pool was the cleanest"
United States
Nina
$60 nightly
The price is $69
Nov 9 - Nov 10
Total with taxes and fees
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2. Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.2 out of 10, Very good, (1,000 reviews)
"Fantastic place to stay! The staff was amazing!"
United States
Catherine
$109 nightly
The price is $126
Nov 22 - Nov 23
Total with taxes and fees
Hampton Inn St. Charles St. Peters

3. Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1,108 reviews)
"Very convenient to downtown St Charles. As per previous visits this hotel is excellent for the price range of the rooms."
United States
Stewart
$127 nightly
The price is $146
Nov 29 - Nov 30
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District

4. Relax Inn Saint Charles

Relax Inn Saint Charles
2.0 star property
St. Charles
6.8 out of 10, (1,000 reviews)
"It was nice"
United States
Christoph
$63 nightly
The price is $72
Nov 5 - Nov 6
Total with taxes and fees
Relax Inn Saint Charles

5. Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,000 reviews)
"Great stay."
United States
Bryan
$92 nightly
The price is $106
Nov 22 - Nov 23
Total with taxes and fees
Comfort Suites St Charles - St Louis

6. Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,152 reviews)
"Rooms are very clean, the staff is friendly and the location is great. We enjoyed are stay."
United States
Matthew
$78 nightly
The price is $92
Nov 8 - Nov 9
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive

7. Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road

Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road
2.0 star property
Westport
6.0 out of 10, (1,008 reviews)
"The staff is amazing"
United States
Vincent
$56 nightly
The price is $65
Nov 11 - Nov 12
Total with taxes and fees
Studio 6 Extended Stay - St Louis, MO - Westport/Craig Road

8. WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.4 out of 10, Very good, (285 reviews)
"I liked the basic, clean room at a very reasonable price."
United States
Joel
$79 nightly
The price is $91
Nov 8 - Nov 9
Total with taxes and fees
WoodSpring Suites St Peters-OFallon

9. Extended Stay America Select Suites St Louis Earth City

Extended Stay America Select Suites St Louis Earth City
2.5 star property
Bridgeton
6.8 out of 10, (937 reviews)
"Management and other staff fantastic. Room was very clean. The kitchen and appliances were clean. Air conditioner worked great 😃"
United States
Charles
$88 nightly
The price is $107
Nov 27 - Nov 28
Total with taxes and fees
Extended Stay America Select Suites St Louis Earth City

10. Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (1,000 reviews)
"a clean location with a helpful staff. Free breakfast was small but good."
United States
Aaron
$85 nightly
The price is $96
Dec 1 - Dec 2
Total with taxes and fees
Quality Inn Foristell

11. The Lodge Hotel and Banquets

The Lodge Hotel and Banquets
2.0 star property
Bridgeton
5.4 out of 10, (565 reviews)
"Very laid back place, everything was fine."
United States
Courtney
$68 nightly
The price is $82
Nov 5 - Nov 6
Total with taxes and fees
The Lodge Hotel and Banquets

12. Best Western Plus St. Louis West-Westport

Best Western Plus St. Louis West-Westport
2.5 star property
Westport
8.0 out of 10, Very good, (1,110 reviews)
"Breakfast and front desk staff were great"
United States
Herb
$84 nightly
The price is $98
Nov 8 - Nov 9
Total with taxes and fees
Best Western Plus St. Louis West-Westport

13. Americas Best Value Inn & Suites St. Louis, St. Charles Inn

Americas Best Value Inn & Suites St. Louis, St. Charles Inn
2.5 star property
St. Charles
5.6 out of 10, (1,003 reviews)
"Staff was extremely accommodating and helpful"
United States
ROSE
$100 nightly
The price is $116
Nov 5 - Nov 6
Total with taxes and fees
Americas Best Value Inn & Suites St. Louis, St. Charles Inn

14. Country Inn & Suites by Radisson, St. Peters, MO

Country Inn & Suites by Radisson, St. Peters, MO
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,006 reviews)
"Great location. Friendly staff decent breakfast."
United States
Heather
$86 nightly
The price is $98
Nov 29 - Nov 30
Total with taxes and fees
Country Inn & Suites by Radisson, St. Peters, MO

15. Motel 6 Maryland Heights, MO

Motel 6 Maryland Heights, MO
2.0 star property
Westport
6.2 out of 10, (1,001 reviews)
"It was great for a quick stay"
United States
Levi
$65 nightly
The price is $76
Nov 5 - Nov 6
Total with taxes and fees
Motel 6 Maryland Heights, MO

16. Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.2 out of 10, Very good, (1,002 reviews)
"Clean room, staff was polite and helpful!"
United States
Tammie
$80 nightly
The price is $92
Nov 10 - Nov 11
Total with taxes and fees
Super 8 by Wyndham St Charles

17. Red Roof Inn St Louis - Westport/ Maryland Heights

Red Roof Inn St Louis - Westport/ Maryland Heights
2.0 star property
Westport
5.4 out of 10, (1,002 reviews)
"Location GREAT Price GREAT Pet friendly GREAT Room wasnt what Id booked, and old but clean. Seemed to have high % of live in day to day paying residents. I felt safe & would rebook again!"
United States
Elizabeth
$58 nightly
The price is $68
Nov 8 - Nov 9
Total with taxes and fees
Red Roof Inn St Louis - Westport/ Maryland Heights

18. Holiday Inn Express Warrenton by IHG

Holiday Inn Express Warrenton by IHG
2.5 star property
Warrenton
9.0 out of 10, Wonderful, (579 reviews)
"Excellent breakfast"
United States
Candy
$122 nightly
The price is $139
Nov 15 - Nov 16
Total with taxes and fees
Holiday Inn Express Warrenton by IHG

19. Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.0 out of 10, Wonderful, (474 reviews)
"The room was clean, the bed was comfy with fluffy pillows. The breakfast had a variety of hot and cold foods. My favorite, the waffle maker. The hotel was conveniently located with a variety of restaurants nearby to choose from."
United States
Judy
$93 nightly
The price is $107
Nov 8 - Nov 9
Total with taxes and fees
Best Western Plus Fenton

20. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
Chesterfield
9.0 out of 10, Wonderful, (1,004 reviews)
"We drove across America and this property stood out by just having the most comfortable beds and a great breakfast , great staff ."
United States
Terry
$110 nightly
The price is $128
Nov 19 - Nov 20
Total with taxes and fees
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Top Defiance Hotel Reviews

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Defiance Motel Guide

Planning a getaway with only a few bucks to spare? Expedia can help! With the inexpensive rates at the top motels in Defiance, St. Louis you can put together the vacation of your dreams without spending every penny of your yearly travel budget.

These smaller places are ideal if you need a home base that lets you easily explore the local sights; many of the best motels in Defiance are located near major freeways and public transportation. Plus, when you book a cheap deal on a motel in Defiance, you’ll find quiet rooms, complimentary toiletries, and comfortable sleeping areas, so you can unwind after a long day.

No matter which motel you choose, don't forget to use the travel tools at Expedia to search for local discounts, compare rates on the hottest motels, and plan your next vacation. You won't believe how budget-friendly an amazing getaway can be.

Also, feel free to check out the motels near me page to find the cheapest deals on motels near your current location.

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