Title: Top Independent in Affton, MO - Expedia.com [Affton Travel Guide](https://expedia.com/Affton.dx72322)[Hotels in Affton](https://expedia.com/Affton-Hotels.d72322.Travel-Guide-Hotels)[Vacation Rentals in Affton](https://expedia.com/Affton-Vacation-Rentals.d72322.Travel-Guide-VacationRentals)[Flights to Affton](https://expedia.com/Cheap-Flights-To-Affton.d72322.Travel-Guide-Flights)[Car Rentals in Affton](https://expedia.com/Car-Rentals-In-Affton.d72322.Car-Rental-Guide)[Affton Vacation Packages](https://expedia.com/Affton.d72322.Destination-Travel-Guides) ![This is the skyline at sunrise. It is situated along the Mississippi River. There are riverboats on the water with the St. Louis Arch in clear view.](https://images.trvl-media.com/place/72322/4c76c201-b7fc-4275-b470-880dcff7f7cf.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/72322/4c76c201-b7fc-4275-b470-880dcff7f7cf.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates Tonight [Mar 24 - Mar 25](https://www.expedia.com/Hotel-Search?regionId=72322&startDate=2026-03-24&endDate=2026-03-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 25 - Mar 26](https://www.expedia.com/Hotel-Search?regionId=72322&startDate=2026-03-25&endDate=2026-03-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=72322&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=72322&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FAffton-Hotels-Independent.0-0-d72322--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FAffton-Hotels-Independent.0-0-d72322--bIndependent.Travel-Guide-Filter-Hotels) ## Top Affton Hotel Reviews ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/3056142b_y.jpg) ### Pear Tree Inn St. Louis Near Union Station 8/10 Good "Free parking and the proximity to the nearby attractions (1min from the St Louis City SC Stadium, 5 min walk to the union station/ferris wheel, 30min walk to the Arch!) makes this hotel a gem! Pool area looked a bit in need of update breakfast is ok (coffee not ok) but again the amenities I mentioned has lots of value in my book. The bed was very comfortable and the view from the 6th floor (ferris wheel and the Arch!) were nice! " [](https://expedia.com/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Near-Union-Station.h26572.Hotel-Information) ![Best Western St. Louis-Kirkwood Route 66](https://images.trvl-media.com/lodging/1000000/10000/500/415/b788e069_y.jpg) ### Best Western St. Louis-Kirkwood Route 66 6/10 Okay "I wasn't expecting much, but the reviews looked promising. The lobby is cute, the room itself was fair. Beds were old and not well made. I cannot forget how terrible the hallway smelled. The hotel is supposed to be smoke free, but the hallway ricked of weed. I'm not sure where it could have come from, but it was so overpowering, by 11pm it was getting inside the room. I wish i had spent a little more and gotten somewhere better." [](https://expedia.com/St-Louis-Hotels-Best-Western-Kirkwood-Inn.h415.Hotel-Information) ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e43b9580_y.jpg) ### Drury Plaza Hotel St. Louis at the Arch 10/10 Excellent "Every was great." [](https://expedia.com/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-At-The-Arch.h546271.Hotel-Information) ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg) ### Home2 Suites by Hilton St. Louis Downtown 2/10 Terrible "The whole hotel smelled like pot. There were hairs on the shower wall. " [](https://expedia.com/St-Louis-Hotels-Home2-Suites-St-Louis-Downtown.h76510729.Hotel-Information) ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/c1e52387_y.jpg) ### Hyatt Regency St. Louis at The Arch 10/10 Excellent "Great hotel in a prime location." [](https://expedia.com/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/b53f4594_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 8/10 Good "Rooms were decent and appeared clean. Hot tub was over chlorinated. " [](https://expedia.com/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc_y.jpg) ### 21C Museum Hotel St Louis 10/10 Excellent "Just a beautiful hotel. It is our 3rd time visiting. And will keep going back. The valet parking is a lot too expensive. I should have asked. But what is one gonna do. My bad. " [](https://expedia.com/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![River City Casino & Hotel](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/71580e9e_y.jpg) ### River City Casino & Hotel 10/10 Excellent "Clean room" [](https://expedia.com/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8_y.jpg) ### Clayton Plaza Hotel & Extended Stay 10/10 Excellent "Stay was wonderful. Would definitely recommend." [](https://expedia.com/St-Louis-Hotels-Clayton-Plaza-Hotel-Extended-Stay.h18144.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [St. Louis Hotels ](https://www.expedia.com/St-Louis-Hotels.d178309.Travel-Guide-Hotels) - [Hotels near Ulysses S. 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