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Duck Key Vacation Rentals

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Our top choices for Duck Key vacation rentals

$369 nightly
The price is $410
Jan 4 - Jan 5, 2026
Total with taxes and fees
Family Oasis Escape | Plush King Bed + Bunk Bed
$1,294 nightly
The price is $1,436
Jan 5 - Jan 6, 2026
Total with taxes and fees
Villa 7218 on Duck Key - 3 BR & 2.5 BA - Boat Slip Available
9.6 out of 10, Exceptional, (46)
"Clean property! Great views! Great communication with owner! Perfect location- close to marathon and key west! "
United States
candi b.
$572 nightly
The price is $636
Jan 5 - Jan 6, 2026
Total with taxes and fees
Villa 5053 on Duck Key Boat Slip Available - 2BD 2.5BA
9.2 out of 10, Wonderful, (18)
"Property was very nice, everything as expected based on listing. Very good place for families."
United States
Nicholas H.
$576 nightly
The price is $640
Jan 11 - Jan 12, 2026
Total with taxes and fees
Villa 5087 on Duck Key Boat Slip Available - 2BD 2.5BA
9.0 out of 10, Wonderful, (8)
"Property was clean and comfortable with an excellent sunset view each evening."
United States
william d.
$567 nightly
The price is $631
Jan 15 - Jan 16, 2026
Total with taxes and fees
Villa 5028 on Duck Key Boat Slip Available - 2BD 2.5BA
8.4 out of 10, Very Good, (10)
"Unit was very clean and had everything we needed"
United States
Vanessa L.
$638 nightly
The price is $709
Jan 5 - Jan 6, 2026
Total with taxes and fees
Villa 5020 on Duck Key Boat Slip Available - 2BD 2.5BA
10.0 out of 10, Exceptional, (1)
"The location was perfect, house was very clean, and the view was breathtaking. We will 100% return."
United States
Gina A.
$649 nightly
The price is $721
Jan 5 - Jan 6, 2026
Total with taxes and fees
Villa 5008 on Duck Key Boat Slip Available - 2BD 1.5BA
9.2 out of 10, Wonderful, (30)
"Wonderful experience, great views, clean rooms, great amount of space. Great price"
United States
Race
$564 nightly
The price is $628
Jan 13 - Jan 14, 2026
Total with taxes and fees
Villa 7075 on Duck Key Boat Slip Available - 2BD 2.5BA
10.0 out of 10, Exceptional, (159)
"Nice place with a Dock. We had an issue but it was taken care of promptly."
United States
Steven B.
$1,111 nightly
The price is $1,233
Jan 11 - Jan 12, 2026
Total with taxes and fees
Waterfront! 4 Bed/3 BA Townhome, 32FTDock, Cabana Club, Paddleboard, Beach Gear!
10.0 out of 10, Exceptional, (13)
"Beautiful views. Very nice accommodations. Wonderfull location!"
United States
michael h.
$606 nightly
The price is $647
Jan 11 - Jan 12, 2026
Total with taxes and fees
Tiny Villa, Big Ocean Views| Breathtaking Sunsets
$964 nightly
The price is $1,070
Jan 11 - Jan 12, 2026
Total with taxes and fees
Discount To Jan 31! 3 Bed, 3 BA Townhome Cabana Club: Oceanfront Beach, Pool!
9.4 out of 10, Exceptional, (32)
"A short weekend getaway was made perfect in this villa. The location is idyllic; especially the balcony overlooking the bay with a perfect sunset view. The home was well-appointed, simple yet all the necessities were covered. Communication with the property manager was excellent. Definitely will book again. "
United States
Natasha A.
$570 nightly
The price is $634
Jan 4 - Jan 5, 2026
Total with taxes and fees
Villa 5023 on Duck Key Boat Slip Available - 2BD 1.5BA
10.0 out of 10, Exceptional, (1)
"Condo was very nice. Screened in porch has a water view with access from the Master, the den and one of the other bedrooms. Enough room in the kitchen for a short term stay. Check in was easy. Close to Marathon. No hand soap or shampoo in unit at check in but owner had some delivered as soon as I requested."
United States
Donald G.
$711 nightly
The price is $790
Jan 4 - Jan 5, 2026
Total with taxes and fees
Villa 4204 on Duck Key Boat Slip Available - 3BD 2BA
9.2 out of 10, Wonderful, (5)
"The villa is in a great location, and has a very private and secluded feeling to it when inside and around the pool. We had a great time, the villa met and exceeded or expectations, there were 6 of us staying there and the age ranges were from 27 to 64, we rented a charter boat out of marathon so the villa location was perfect.Thank you very much for such a great place to stay, we will try and stay here again if we come back down."
United States
Kevin J.
$1,294 nightly
The price is $1,436
Jan 10 - Jan 11, 2026
Total with taxes and fees
4 Bedroom 3 Bathroom Sanctuary Villa W/ Private Pool & 35ft dock upon request
$434 nightly
The price is $482
Jan 4 - Jan 5, 2026
Total with taxes and fees
Poolside Room | Direct Pool Access + Lanai
$561 nightly
The price is $623
Jan 10 - Jan 11, 2026
Total with taxes and fees
Captain's Suite | Island View | No Hidden Fee
$456 nightly
The price is $507
Jan 4 - Jan 5, 2026
Total with taxes and fees
ADA Family Room | Resort Perks | No Hidden Fee
$1,294 nightly
The price is $1,436
Jan 5 - Jan 6, 2026
Total with taxes and fees
Villa 7205 on Duck Key - 3 BR & 2.5 BA - Boat Slip available
$305 nightly
The price is $339
Jan 4 - Jan 5, 2026
Total with taxes and fees
Tropical Escape | King Room w/ Resort Perks
$305 nightly
The price is $339
Jan 4 - Jan 5, 2026
Total with taxes and fees
Duck Key | 2Q ADA Rm w/ Balcony | No Hidden Fee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Duck Key Hotel Reviews

Find out more about Duck Key

Everything you need to know about Duck Key vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Duck Key vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Duck Key vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Duck Key vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Duck Key. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Duck Key in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $152 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Duck Key rentals

At Expedia, we put the best Duck Key vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Duck Key rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Duck Key vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Duck Key. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.