Top 10 Hotels in Penermon, MO (from $57) 2026 - Competitive Prices

Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Learn about One Key
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Penermon

Pet friendly

Apartment

Condo

Pool

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Penermon hotels

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

A hotel with a brick facade, multiple windows, and a covered entrance area.

1. Econo Lodge Dexter

Dexter

Herman

$51 nightly

$57 total

Oct 22 - Oct 23

Total with taxes and fees

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

2. Hampton Inn By Hilton Dexter

Dexter

Kendall

$98 nightly

$110 total

Oct 4 - Oct 5

Total with taxes and fees

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

3. Dexter Inn

Dexter

Edward

$61 nightly

$68 total

Oct 24 - Oct 25

Total with taxes and fees

A diner with booth seating, a checkered floor, and a counter with a cash register.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

4. Travelodge by Wyndham Dexter

Dexter

Steven

$95 nightly

$107 total

Oct 1 - Oct 2

Total with taxes and fees

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

5. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

$94 nightly

$108 total

Sep 27 - Sep 28

Total with taxes and fees

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

6. Hampton Inn Sikeston

Sikeston

John

$102 nightly

$115 total

Oct 11 - Oct 12

Total with taxes and fees

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

7. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

$101 nightly

$114 total

Oct 1 - Oct 2

Total with taxes and fees

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A buffet with various food items, including omelets and baked goods, served in metal containers.

An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

8. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

michael

$105 nightly

$119 total

Oct 4 - Oct 5

Total with taxes and fees

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

A bathroom with a bathtub, toilet, and a shower curtain.

A Hickory House Inn with a clear sky, a parking lot, and a covered entrance.

A row of single-story brick buildings with attached garages, likely a motel or small hotel, with a parking lot in front and a grassy area with a gazebo.

9. OYO Hickory House Inn

Dexter

Tammy

$77 nightly

$86 total

Sep 24 - Sep 25

Total with taxes and fees

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

10. TownePlace Suites by Marriott Sikeston

Sikeston

Stacy

$109 nightly

$123 total

Oct 1 - Oct 2

Total with taxes and fees

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

11. Best Western Plus Sikeston I-55

Sikeston

Shelley

$87 nightly

$99 total

Sep 27 - Sep 28

Total with taxes and fees

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A reception area with a sign for 'Travel Inn and Suites'.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

12. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Sharika West

$59 nightly

$67 total

Oct 7 - Oct 8

Total with taxes and fees

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

13. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

$66 nightly

$76 total

Sep 27 - Sep 28

Total with taxes and fees

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel kitchen with a long counter, various appliances, and a tiled backsplash.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A motel with a covered entrance, multiple rooms, and a parking lot.

14. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

William

$57 nightly

$65 total

Sep 29 - Sep 30

Total with taxes and fees

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

15. Comfort Inn & Suites Sikeston I-55

Sikeston

Starlette

$89 nightly

$102 total

Oct 13 - Oct 14

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a counter, a coffee machine, and seating.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

16. Country Yard Inn and Suite

Sikeston

William

$57 nightly

$64 total

Oct 24 - Oct 25

Total with taxes and fees

A bedroom with a bed, bedside table, lamp, and a view of the bathroom.

A hallway with vending machines, including a Pepsi and a Coca-Cola machine, and a door at the end.

A covered outdoor area with brick walls, windows, and a seating area with a chair and a trash can.

A reception desk with a pet fee sign, no smoking sign, and a pet bell sign.

17. OYO Malden Airport Inn

Malden

James

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Penermon Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"."

Hampton Inn Sikeston

10/10 Excellent

"Staff was great"

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent

"This was a very good value. It has been the best hotel I've stayed at in awhile."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"The man at the front desk was very helpful and polite"

TownePlace Suites by Marriott Sikeston

10/10 Excellent

"My overall experience was amazing from the time I checked in until I left. The staff were super pleasant and incredible. My room was clean and spacious. I never been in an extended stay room before. I definitely will be booking a suite like this one again."

Hampton Inn By Hilton Dexter

8/10 Good

"Very nice hotel - our favorite when we visit the grandkids! Our only issue this time was with housekeeping. We arrived Friday afternoon, asked that our room be serviced on Sunday, (they only do it every other day), and it was not done. Also, in the shower were the usual shampoo and shower gel, but instead of conditioner, the 3rd dispenser was body lotion! I asked if the lotion could be replaced with conditioner - didn’t happen. Disappointed!"

OYO Hickory House Inn

10/10 Excellent

"Nice for overnight stop"

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

10/10 Excellent

"We had an excellent stay here. The host was very nice and make sure that we had everything we needed. If we come back here, we will definitely try to get this house again.Needless to say, we were very pleased with our day."

OYO Malden Airport Inn

10/10 Excellent

"Clean room, quiet. "

More cheap stays in Penermon

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

$57 nightly

$65 total

Sep 29 - Sep 30

Total with taxes and fees

7/10 Good! (676 reviews)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO

$59 nightly

$67 total

Oct 7 - Oct 8

Total with taxes and fees

8.4/10 Very Good! (822 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

$66 nightly

$76 total

Sep 27 - Sep 28

Total with taxes and fees

7.2/10 Good! (1,007 reviews)

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

$87 nightly

$99 total

Sep 27 - Sep 28

Total with taxes and fees

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

$102 nightly

$115 total

Oct 11 - Oct 12

Total with taxes and fees

9/10 Wonderful! (624 reviews)

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

$105 nightly

$119 total

Oct 4 - Oct 5

Total with taxes and fees

Hotels in Penermon with star-rating

Frequently asked questions

Where is the best place to stay in Penermon?

Located 17.7 mi (28.4 km) from the heart of Penermon, Drury Inn & Suites Sikeston, MO is a top choice for your stay based on our traveler data. Two other options for your trip to the area are Days Inn and Suites by Wyndham Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in Penermon.

What's the top vacation rental that Penermon has to offer?

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: Visitors like this Penermon vacation home rental. It offers a fireplace, a balcony, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. See all vacation rentals in Penermon.

If I need to cancel my hotel reservation in Penermon, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Penermon.

Where can I learn more about changing or cancelling my trip to Penermon?

For more details about picking new dates or cancelling your trip to Penermon, go to https://www.expedia.com/service/.

How is it staying in Penermon?

Those traveling to Penermon are sure to enjoy the sights to see and things to do. There are 29 hotels and other accommodations in the surrounding area. Find out more about Penermon.

What should I see while I'm in Penermon?

Places to visit in the wider area include Dexter Welcome Center Depot and Museum, Keller Veteran Memorial, and Sikeston Depot Museum. You'll also find Stoddard County Civil War Memorial Cemetery and The Heritage House in the area. Check out what more to see and do in Expedia's Penermon guide.

What's the weather like in Penermon?

The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 41°F. Average annual precipitation for Penermon is 52 inches.

Find hotels in Penermon, MO from $57

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Penermon

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Penermon hotels

1. Econo Lodge Dexter

2. Hampton Inn By Hilton Dexter

3. Dexter Inn

4. Travelodge by Wyndham Dexter

5. Drury Inn & Suites Sikeston, MO

6. Hampton Inn Sikeston

7. Fairfield Inn & Suites by Marriott Sikeston

8. Holiday Inn Express & Suites Sikeston Southwest by IHG

9. OYO Hickory House Inn

10. TownePlace Suites by Marriott Sikeston

11. Best Western Plus Sikeston I-55

12. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

13. Days Inn and Suites by Wyndham Sikeston

14. Super 8 by Wyndham Sikeston/Miner Area

15. Comfort Inn & Suites Sikeston I-55

16. Country Yard Inn and Suite

17. OYO Malden Airport Inn

Top Penermon Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Hampton Inn Sikeston

Days Inn and Suites by Wyndham Sikeston

Super 8 by Wyndham Sikeston/Miner Area

TownePlace Suites by Marriott Sikeston

Hampton Inn By Hilton Dexter

OYO Hickory House Inn

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

OYO Malden Airport Inn

More cheap stays in Penermon

Super 8 by Wyndham Sikeston/Miner Area

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston I-55

Hampton Inn Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hotels in Penermon with star-rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app