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Find 2 Star Hotels in Sikeston, MO from $65

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Check availability on Sikeston 2 Star Hotels

Tonight
Oct 7 - Oct 8
Tomorrow
Oct 8 - Oct 9
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Sikeston 2-star hotels

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.
A Dear Tree Inn building with a covered entrance and a clear sky at dusk.
A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.
A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

1. Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
Cape Girardeau
United States
Elizabeth
$72 nightly
$81 total
Oct 18 - Oct 19
Total with taxes and fees
Pear Tree Inn Cape Girardeau West
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.
A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.
Lobby
A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

2. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
Sikeston
United States
David
$66 nightly
$76 total
Nov 1 - Nov 2
Total with taxes and fees
Days Inn and Suites by Wyndham Sikeston
A hotel room with two beds, a desk, a chair, a TV, and a projector screen.
A reception area with two reception desks, a wall-mounted sign, and a refrigerator.
A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.
A buffet with various food items, including omelets and other dishes, with clear signage indicating the type of food.

3. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Murphysboro
United States
Lauren
$108 nightly
$120 total
Nov 1 - Nov 2
Total with taxes and fees
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.
A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.
A hotel kitchen with a long counter, various appliances, and a tiled backsplash.
A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

4. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
Sikeston
United States
William
$57 nightly
$65 total
Oct 14 - Oct 15
Total with taxes and fees
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.
A hotel lobby with a seating area, a reception desk, and a bar.
A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.
A kitchen counter with a coffee machine, a kettle, and storage boxes.

5. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
Perryville
United States
Lisa
$101 nightly
$116 total
Nov 1 - Nov 2
Total with taxes and fees
Holiday Inn Express & Suites Perryville by IHG
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

6. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
United States
Rebecca
$101 nightly
$115 total
Oct 11 - Oct 12
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.
A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.
A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

7. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
Sikeston
United States
Shelley
$84 nightly
$96 total
Oct 11 - Oct 12
Total with taxes and fees
Best Western Plus Sikeston I-55
A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.
A hotel patio with a gazebo, outdoor seating, and a view of the road.
An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.
A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

8. Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
Cape Girardeau
United States
Samuel
$85 nightly
$101 total
Oct 11 - Oct 12
Total with taxes and fees
Candlewood Suites Cape Girardeau by IHG
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.
An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.
A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.
A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

9. Hampton Inn Sikeston

Hampton Inn Sikeston
Sikeston
United States
Carolyn
$105 nightly
$120 total
Oct 18 - Oct 19
Total with taxes and fees
Hampton Inn Sikeston
A modern retail area with a display of local items and snacks.
A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.
A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.
A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

10. Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
Cape Girardeau
United States
Shannon
$89 nightly
$102 total
Oct 14 - Oct 15
Total with taxes and fees
Tru By Hilton Cape Girardeau
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.
A hotel with a covered entrance, a sign for the brand, and a parking lot with cars.
A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.
A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

11. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
Charleston
United States
William
$60 nightly
$67 total
Oct 8 - Oct 9
Total with taxes and fees
Super 8 by Wyndham Charleston/Sikeston East MO
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.
A reception area with a reception desk, a large wall-mounted sign, and a potted plant.
A kitchenette with a coffee machine, a kettle, and storage shelves.
A buffet with various food items, including omelets and baked goods, served in metal containers.

12. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
Sikeston
United States
Melissa
$101 nightly
$115 total
Oct 18 - Oct 19
Total with taxes and fees
Holiday Inn Express & Suites Sikeston Southwest by IHG
A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.
A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'
A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.
A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

13. Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
Cape Girardeau
United States
Danny
$59 nightly
$67 total
Nov 1 - Nov 2
Total with taxes and fees
Quality Inn Cape Girardeau North
A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.
A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.
A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.
A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

14. Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
Perryville
United States
paulette
$69 nightly
$79 total
Nov 1 - Nov 2
Total with taxes and fees
Super 8 by Wyndham Perryville
A modern hotel lobby with a bar area, seating, and artwork on the walls.
A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.
A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.
A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

15. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Kendall
$98 nightly
$111 total
Oct 18 - Oct 19
Total with taxes and fees
Hampton Inn By Hilton Dexter
A building with a fountain and flower beds in front.
A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.
A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.
A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

16. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
Charleston
United States
Kathleen
$66 nightly
$74 total
Oct 10 - Oct 11
Total with taxes and fees
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.
A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.
A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.
A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

17. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
United States
Craig
$58 nightly
$66 total
Oct 8 - Oct 9
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
An indoor swimming pool with clear water, marked lanes, and a lifeguard warning sign.
A hotel room with two beds, a television, a desk, and a large cityscape painting on the wall.
A dining area with wooden flooring, red upholstered chairs, and a mural of a pyramid.
A hotel room with a treadmill, exercise bike, and dumbbells.

18. Hotel 7 Inn Anna

Hotel 7 Inn Anna
Anna
United States
Dorothy J
Hotel 7 Inn Anna
A spacious dining area with high ceilings, large windows, and modern lighting fixtures.
A gym with exercise equipment, a treadmill, and a wall-mounted TV.
An outdoor patio with stone walls, wicker furniture, and large windows.
A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

19. Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
Cape Girardeau
United States
Rebekah
$106 nightly
$119 total
Oct 18 - Oct 19
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East
A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.
A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.
A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.
A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

20. Dexter Inn

Dexter Inn
Dexter
United States
Edward
$69 nightly
$78 total
Oct 8 - Oct 9
Total with taxes and fees
Dexter Inn
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Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Sikeston.
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
$100 nightly
$113 total
Oct 12 - Oct 13
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
$94 nightly
$108 total
Oct 18 - Oct 19
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
Drury Inn & Suites Sikeston, MO
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3003 SOUTH OLD ORCHARD ROAD Jackson MO
$81 nightly
$87 total
Nov 1 - Nov 2
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
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Top Sikeston Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

8/10 Good
"Everything was good about the room except the bathroom. The stopper on the sink did not work and there was a dent in the wall. The face/wash towels need to be changed out. They are no longer white. They are dull in color. The couch needs to be cleaned and freshen. The staff was excellent and everything else is good. I just wish that breakfast offered hot eggs and meat vs. only waffles. Otherwise the room was good."
James 3-night trip
Posted 1 day ago
Days Inn and Suites by Wyndham Sikeston
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
"Great place"
BRANDY 1-night trip
Posted 4 days ago
Super 8 by Wyndham Sikeston/Miner Area

Price trends for properties with 2 Stars in Sikeston

Less expensive
More expensive
This month
Next month
June
April
$80
$86
Month
Price
January
$83
February
$91
March
$93
April
$98
May
$96
June
$76
July
$77
August
$78
September
$92
October
$80
November
$86
December
$78
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed properties with 2 stars in Sikeston. Select dates and complete search for nightly totals inclusive of taxes and fees.

Find out more about Sikeston

When you've got to get away to a new or favorite destination without breaking the bank, Sikeston awaits with comfortable 2 Star hotels and a change of scenery. Find a new fave boutique or hiking trail nearby and enjoy some R & R, or stay on your feet visiting the top attractions that draw several of visitors. You're about to find out why both locals and travelers love this place.

The Right Place at the Perfect Price

2 Star hotels are in high demand in Sikeston. You'll find the best deals right here, so book early and save on a great getaway. Thanks to budget-friendly prices and traveler-friendly amenities, you'll find a place to stay that's just right for you. Stay here and be one of the first guests to leave a review and share your thoughts. So, savor the comfort of a well-kept room and attentive hospitality. When you book with Expedia, you can stay all over the world, and the journey starts in Sikeston.

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Book your stay in this popular place today -- Sikeston is a destination on the rise. It's no secret that Sikeston is a great place to stay, so get the best deals while they're still available, and get to know exactly what everyone loves about Sikeston. Your home away from home is waiting. Book the best deals on 2-star hotels and 2 Star hotels in Sikeston now.

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