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Oct 16 - Oct 17
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Our top choices for Santa Fe hotels

A modern kitchen area with a central counter, various food stations, and a chalkboard menu.
Pool
Fitness facility
A hotel room with two beds, a desk, a chair, a TV, and a couch.

1. Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
Alachua
United States
Pamela
$110 nightly
$123 total
Oct 25 - Oct 26
Total with taxes and fees
Hampton Inn & Suites Alachua I-75
A spacious indoor dining area with multiple tables and chairs, large windows offering a view of palm trees and greenery outside.
A modern office space with a reception desk, several chairs, a large window, and a colorful abstract painting on the wall.
A Holiday Inn Express & Suites hotel with a modern design, multiple floors, and a parking lot.
A lobby with a patterned carpet, two green armchairs, a white sofa, a small round table with a plant, and framed artwork on the wall.

2. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Alachua
United States
Harold
$106 nightly
$119 total
Oct 25 - Oct 26
Total with taxes and fees
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
A modern hotel with a prominent 'La Quinta' sign, a covered entrance, and a well-maintained outdoor area with a parking lot.
A hotel reception area with directional signs for elevators, floor 1, pool restrooms, and business center.
A modern lounge area with a flat-screen TV, a fireplace, teal and brown seating, patterned carpet, and a wall-mounted clock.
A modern kitchen with blue-tiled walls, stainless steel appliances, and a central island.

3. La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
Gainesville
United States
Edwin
$91 nightly
$102 total
Oct 18 - Oct 19
Total with taxes and fees
La Quinta by Wyndham Gainesville
A large, multi-story hotel with a central courtyard, palm trees, and an American flag.
A spacious dining area with multiple tables and chairs, a kitchen area with a coffee station, and large windows allowing natural light.
A living room with a brown leather sofa, a glass-top coffee table, and a framed picture on the wall.
A spacious lobby with a large painting, a fireplace, a piano, and multiple seating areas.

4. Best Western Gateway Grand

Best Western Gateway Grand
Gainesville
United States
Diane
$93 nightly
$104 total
Oct 18 - Oct 19
Total with taxes and fees
Best Western Gateway Grand
A stone water feature with cascading water, surrounded by a brick wall and greenery.
A reception desk with a modern design, a ceiling fan, and a seating area with chairs and a table.
A neatly arranged bedroom with a bed, bedside lamps, a TV, and a mirror.
A covered outdoor area with a paved walkway leading to a seating area, surrounded by greenery and a clear sky.

5. BlueGem Motel

BlueGem Motel
High Springs
United States
Myra
$91 nightly
$102 total
Oct 18 - Oct 19
Total with taxes and fees
BlueGem Motel
A cozy restaurant with wooden beams, yellow walls, and a bar area with coffee machines.
A hotel room with a bed, a desk with a chair, a television, a mirror, and a wardrobe.
A spacious lobby with a dining area, a kitchen, and a large window providing a view of the outdoors.
A reception desk with a sign reading "Quality by Choice Hotels," surrounded by various reptile decorations.

6. Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
Alachua
United States
Deborah
$73 nightly
$82 total
Nov 15 - Nov 16
Total with taxes and fees
Quality Inn Alachua - Gainesville Area
A modern hotel room with a large bed, a desk, a chair, and a TV.
A gym with treadmills, exercise balls, and dumbbells.
A workspace with two chairs, a desk, a computer monitor, and a wall-mounted sign reading 'BUSINESS CENTER'.
A motel with a covered entrance, multiple parking spaces, and a fire extinguisher on the wall.

7. Clarion Pointe Alachua - Gainesville Area

Clarion Pointe Alachua - Gainesville Area
Alachua
United States
Josey
$63 nightly
$71 total
Nov 2 - Nov 3
Total with taxes and fees
Clarion Pointe Alachua - Gainesville Area
A hotel room with a bed, bedside tables, a desk, a chair, a mirror, and a window.
A corner room with two checkered chairs, a small table, a framed picture on the wall, and a floor lamp.
A building with a Coca-Cola vending machine, a window with a 'OPEN' sign, and a red awning.
A reception area with a counter, a computer, and a bulletin board with pamphlets.

8. Palms Garden Inn

Palms Garden Inn
Lake City
United States
Igor
$63 nightly
$71 total
Nov 16 - Nov 17
Total with taxes and fees
Palms Garden Inn
A person pouring a drink into a glass.
A spacious hotel lobby with a checkered carpet, wooden paneling, and two large chandeliers.
A hotel room with a sofa, a desk, a chair, a bed, a TV, and a dining table with a glass and cookie.
A modern gym with treadmills, exercise bikes, and weight equipment.

9. Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG
Gainesville
United States
Arleana
$102 nightly
$115 total
Oct 22 - Oct 23
Total with taxes and fees
Hotel Indigo Gainesville-Celebration Pointe by IHG
A spacious lobby with a sectional sofa, a wooden cabinet, and a television mounted on the wall.
A modern kitchen with wooden cabinets, a granite countertop, and pendant lighting.
A hotel room with a large window offering a view of a cityscape, a blue armchair, and a small table with a lamp.
A hotel lobby with a stone wall, a flat-screen TV, orange upholstered seating, and a lamp.

10. Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
Gainesville
United States
Adam
$106 nightly
$119 total
Oct 21 - Oct 22
Total with taxes and fees
Drury Inn & Suites Gainesville
An outdoor patio with wicker furniture, stone walls, and a barbecue grill.
A modern hotel room with a flat-screen TV, a dining area with a table and chairs, a kitchenette, and a wardrobe with hanging space.
TownePlace Suites Marriott with a modern exterior, multiple windows, and a covered entrance area.
A modern living room with a sectional sofa, a standing lamp, a large window with sheer curtains, a flat-screen TV, and a built-in air conditioning unit.

11. TownePlace Suites by Marriott Gainesville Northwest

TownePlace Suites by Marriott Gainesville Northwest
Gainesville
United States
Tanya
$105 nightly
$118 total
Oct 19 - Oct 20
Total with taxes and fees
TownePlace Suites by Marriott Gainesville Northwest
A modern breakfast area with labeled dispensers for yogurt, eggs, and milk, a coffee machine, and a chalkboard menu.
A Holiday Inn Express building with a modern design, featuring multiple windows and a flat roof.
A hotel room with two beds, a TV, a desk, and a chair.
An outdoor patio with tables and chairs, a stone wall, and a view of a street with trees and buildings.

12. Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
Starke
United States
Judy
$103 nightly
$114 total
Nov 15 - Nov 16
Total with taxes and fees
Holiday Inn Express Starke by IHG
A modern bar area with wooden bar stools, pendant lighting, and artwork on the walls.
A hotel hallway with carpeted floors, doors on both sides, and overhead lighting.
A hotel room with a kitchenette, a bed, a desk with a chair, and a bathroom.
A hotel room with a living area, kitchenette, and a large mirror.

13. Hampton Inn Gainesville

Hampton Inn Gainesville
Gainesville
United States
Ross
$99 nightly
$111 total
Oct 19 - Oct 20
Total with taxes and fees
Hampton Inn Gainesville
A swimming pool with a metal ladder, surrounded by a white fence and green chairs.
A refrigerated display case with beverages and snacks, and a shelf with bottled water and other beverages.
A living room with a curved sofa, a wooden cabinet, and a fish tank.
A hotel room with a bed, a sofa, a coffee table, and a small table with a lamp.

14. Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
Waldo
United States
Christine
$84 nightly
$95 total
Oct 24 - Oct 25
Total with taxes and fees
Best Western Waldo Inn and Suites
A cabin with a cozy interior, a dining area, and a view of the forest.
A cozy cabin interior with a wooden interior, a dining table with a chair, a window, and a hanging lantern.
A bedroom with a wooden headboard, a bed with white linens, a window with a view of green foliage, and a tray with breakfast items.
Private kitchen

15. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
High Springs
United States
Katie
$198 nightly
$218 total
Nov 16 - Nov 17
Total with taxes and fees
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
A hotel room with two beds, a desk, a chair, a television, and a bathroom visible through an open door.
A hotel room with a dining area, a sofa, a TV, and a ceiling fan.
A reception area with a dark wooden reception desk, a large white floral wall art, and a tiled floor.
A hotel room with a carpeted floor, a desk with a lamp, two yellow armchairs, a sofa, and a television.

16. Days Inn by Wyndham Gainesville University I-75

Days Inn by Wyndham Gainesville University I-75
Gainesville
United States
Cheryl
$72 nightly
$81 total
Oct 17 - Oct 18
Total with taxes and fees
Days Inn by Wyndham Gainesville University I-75
A multi-story hotel with a central entrance, palm trees, and a clear sky.
A modern living room with a green sofa, a round coffee table, and a fireplace.
A hotel room with a wooden floor, a red armchair, a beige sofa, a TV, and framed artwork on the wall.
A spacious hotel lobby with a modern staircase, a seating area with a sofa and chairs, and a dining area in the background.

17. Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
Gainesville
United States
sherry
$88 nightly
$99 total
Oct 25 - Oct 26
Total with taxes and fees
Country Inn & Suites by Radisson, Gainesville, FL
A hotel room with two beds, a desk, a chair, and a television.
A bathroom with a white sink, mirror, and towel rack.
A motel with a two-story structure, a covered front entrance, and a parking lot with several cars.
A parking lot with marked lanes and a grassy area on one side.

18. Royal Inn

Royal Inn
Alachua
United States
James
$66 nightly
$74 total
Oct 18 - Oct 19
Total with taxes and fees
Royal Inn
A room with a wooden ceiling, two beds with patterned bedding, a desk, and a chair.
A stone outdoor seating area with a table and benches, a trash bin, and a building in the background.
A row of motel buildings with a fire hydrant and trees in front.
A small building with a green roof, a covered porch with wicker chairs, and a table.

19. High Springs Country Inn

High Springs Country Inn
High Springs
United States
Paige
$77 nightly
$86 total
Nov 16 - Nov 17
Total with taxes and fees
High Springs Country Inn
A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.
A living room with a grey sofa, a wooden coffee table, and a framed horse picture on the wall.
A narrow kitchen with a wooden ceiling, a green refrigerator, and a wooden countertop.
Room

20. Vista Verde Farm Retreat

Vista Verde Farm Retreat
Lake City
United States
Stacy
$181 nightly
$203 total
Oct 19 - Oct 20
Total with taxes and fees
Vista Verde Farm Retreat
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Top Santa Fe Hotel Reviews

Best Western Gateway Grand

Best Western Gateway Grand

8/10 Good
"La habitacion limpia y comoda sin mal olor El desayuno no mos gustó. Igual gracias a todos. Las sabanas estan amarillas y transparentes igual que los paños amarillos El personal muy amable."
Marianela 1-night trip
Posted 3 hours ago
Best Western Gateway Grand
La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville

8/10 Good
"Everything was great except for the overwhelming scented spray that was used in the room."
Vicki 1-night trip
Posted 3 hours ago
La Quinta by Wyndham Gainesville
Hotel Indigo Gainesville-Celebration Pointe by IHG

Hotel Indigo Gainesville-Celebration Pointe by IHG

10/10 Excellent
"Beautiful, well maintained property. Walkable to restaurants and shopping and parking is free and convenient. We only stayed there one night, but if I’m ever Gainesville again – this will be my top choice!"
Courtney 1-night trip
Posted 5 hours ago
Hotel Indigo Gainesville-Celebration Pointe by IHG
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

8/10 Good
"The mattress was firmer than I like. It seemed that the breakfast eggs were either powdered eggs or pre-prepared yolk liquid. The separation of the stations was nice once I realized that was the setup. I didn't see any milk if the diner needed it for cereal or to drink."
Diane 1-night trip
Posted 10 hours ago
Sleep Inn & Suites University/Shands
Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

10/10 Excellent
"I had a beautiful room for my very brief stay. My room was perfect, clean and very relaxing. The staff were helpful. I'll be back again soon."
Glenn 1-night trip
Posted 12 hours ago
Drury Inn & Suites Gainesville
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

10/10 Excellent
"It was super clean and the staff helped me get the room i exactly needed with no problem. Super sweet. Breakfast was also a plus better then some ive had before but not the best ive had. If your looking for somthing quick and easy too stay in or just for a few nights 100% recommend."
jessica 2-night trip
Posted 2 days ago
HOM Hotel Gainesville, SureStay Collection by Best Western
DoubleTree by Hilton Gainesville

DoubleTree by Hilton Gainesville

8/10 Good
"Check in staff was great but during check out there was 1 girl at desk, she was on the phone for about 15 mins. Didn’t even acknowledge me, I had to interrupt her conversation to ask if there was someone else who could help and she said no and proceeded to talk on the phone."
Alicia 1-night trip
Posted 2 days ago
DoubleTree by Hilton Gainesville

More cheap stays in Santa Fe

Red Roof Inn PLUS+ Gainesville

Red Roof Inn PLUS+ Gainesville

3500 Southwest 42nd St Gainesville FL
$57 nightly
$64 total
Oct 20 - Oct 21
Total with taxes and fees
Red Roof Inn PLUS+ Gainesville
Days Inn by Wyndham Gainesville University I-75

Days Inn by Wyndham Gainesville University I-75

920 Nw 69th Ter Gainesville FL
$72 nightly
$81 total
Oct 17 - Oct 18
Total with taxes and fees
Days Inn by Wyndham Gainesville University I-75
HOM Hotel Gainesville, SureStay Collection by Best Western

HOM Hotel Gainesville, SureStay Collection by Best Western

3905 Sw 43Rd St Gainesville FL
$72 nightly
$82 total
Oct 25 - Oct 26
Total with taxes and fees
8.6/10 Excellent! (2,149 reviews)
HOM Hotel Gainesville, SureStay Collection by Best Western
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

4110 SW 40th Boulevard Gainesville FL
$85 nightly
$96 total
Nov 8 - Nov 9
Total with taxes and fees
8.8/10 Excellent! (1,313 reviews)
Sleep Inn & Suites University/Shands
Comfort Inn Gainesville - University Area

Comfort Inn Gainesville - University Area

3440 SW 40th Blvd Gainesville FL
$86 nightly
$96 total
Oct 25 - Oct 26
Total with taxes and fees
Comfort Inn Gainesville - University Area
Comfort Suites Gainesville near University

Comfort Suites Gainesville near University

2603 SW 13TH STREET Gainesville FL
$88 nightly
$99 total
Nov 8 - Nov 9
Total with taxes and fees
Comfort Suites Gainesville near University

Hotels in Santa Fe with star-rating

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 18.6 mi (30 km) from the heart of Santa Fe, Drury Inn & Suites Gainesville is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Sleep Inn & Suites University/Shands and Country Inn & Suites by Radisson, Gainesville, FL. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best vacation rentals in Santa Fe?
5BR UF Family Retreat with Private Pool, Pond, Game Room – Sleeps 10: This vacation home rental outside of Santa Fe is located on a lake and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
Where can I learn more about changing or cancelling my trip to Santa Fe?
To access more information about picking new dates or cancelling your trip to Santa Fe, go to https://www.expedia.com/service/.
What is staying in Santa Fe like?
Travelers to Santa Fe will find plenty to explore and enjoy. There are 796 hotels and other accommodations in the surrounding area. Find out more about Santa Fe.
What are the top places to visit in Santa Fe?
Places to visit in the wider area include Turkey Creek Golf Course, O'Leno State Park, and San Felasco Hammock Preserve State Park. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Check out what more to see and do in Expedia's Santa Fe guide.
What's the seasonal weather like in Santa Fe?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 59°F. The rainiest months in Santa Fe are August, June, July, and September, with each month seeing an average of 7 inches of rainfall.

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