Find hotels in Santa Fe, FL from $56

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Fe hotels

Sweetwater Branch Inn

Sweetwater Branch Inn
3.5 star property
Gainesville
9.6 out of 10, Exceptional, (993 reviews)
"This was a very charming place to stay at. The staff was friendly and were accommodating when we needed a late check-in time. We also brought our dog and liked that there were several pet-friendly rooms. Would definitely stay here again if we're back in Gainesville!"
United States
Shirly
$137 nightly
The price is $155
Jan 26 - Jan 27
Total with taxes and fees
Sweetwater Branch Inn

Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar

Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar
4.0 star property
Gainesville
8.6 out of 10, Excellent, (9 reviews)
"Clean, comfortable, "
United States
Beth
$222 nightly
The price is $250
Jan 24 - Jan 25
Total with taxes and fees
Grand Two Bedroom Two Bathroom Apartment with Balcony by The Scholar

Staybridge Suites Gainesville I-75 by IHG

Staybridge Suites Gainesville I-75 by IHG
3.0 star property
Gainesville
9.4 out of 10, Exceptional, (918 reviews)
"Great hotel with clean rooms and friendly staff!"
United States
Denise
$139 nightly
The price is $156
Jan 25 - Jan 26
Total with taxes and fees
Staybridge Suites Gainesville I-75 by IHG

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.4 out of 10, Very Good, (19 reviews)
"Great remodel of a retro motel."
United States
Kathleen
$63 nightly
The price is $71
Jan 26 - Jan 27
Total with taxes and fees
High Springs Country Inn

Royal Inn

Royal Inn
2.0 star property
Alachua
7.2 out of 10, Good, (192 reviews)
"Good value and close to highway. "
United States
Ross
$72 nightly
The price is $81
Jan 25 - Jan 26
Total with taxes and fees
Royal Inn

Depot Village

Depot Village
2.0 star property
Gainesville
9.6 out of 10, Exceptional, (79 reviews)
"The cleanest room I have seen in years an amazing place to stay amazing people coffee shop on site perfect for a little getaway with downtown close by."
United States
Megan
$103 nightly
The price is $115
Jan 26 - Jan 27
Total with taxes and fees
Depot Village

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (402 reviews)
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
United States
Julians
$86 nightly
The price is $97
Jan 29 - Jan 30
Total with taxes and fees
BlueGem Motel

TownePlace Suites by Marriott Gainesville Northwest

TownePlace Suites by Marriott Gainesville Northwest
3.0 star property
Gainesville
8.4 out of 10, Very Good, (660 reviews)
"Good hotel"
United States
Jason
$98 nightly
The price is $110
Jan 26 - Jan 27
Total with taxes and fees
TownePlace Suites by Marriott Gainesville Northwest

Alachua Inn

Alachua Inn
2.0 star property
Alachua
5.8 out of 10, (660 reviews)
"Staff was very nice"
United States
Nekia
$66 nightly
The price is $74
Jan 26 - Jan 27
Total with taxes and fees
Alachua Inn

Hampton Inn Gainesville

Hampton Inn Gainesville
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,002 reviews)
"The checkin staff was wonderful, welcoming me back from my last stay."
United States
SanJuana
$94 nightly
The price is $106
Feb 2 - Feb 3
Total with taxes and fees
Hampton Inn Gainesville

Courtyard by Marriott Gainesville FL

Courtyard by Marriott Gainesville FL
3.0 star property
Gainesville
8.6 out of 10, Excellent, (671 reviews)
"Top shelf hotel with great staff and delicious breakfast. "
United States
Connie
$93 nightly
The price is $105
Feb 2 - Feb 3
Total with taxes and fees
Courtyard by Marriott Gainesville FL

Aloft Gainesville University Area

Aloft Gainesville University Area
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,000 reviews)
"Great location for us to stop on our way to Miami and the staff Wednesday evening and Thursday morning were so sweet and helpful. "
United States
David
$96 nightly
The price is $108
Feb 8 - Feb 9
Total with taxes and fees
Aloft Gainesville University Area

Residence Inn by Marriott Gainesville I-75

Residence Inn by Marriott Gainesville I-75
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (753 reviews)
"Our visit was good overall! However, there was a lot of hair in the shower and sink. Shower could have been cleaner overall. Other than that the room was fine. Bed was very comfortable. Just know this is an older hotel."
United States
Mariah
$97 nightly
The price is $109
Feb 8 - Feb 9
Total with taxes and fees
Residence Inn by Marriott Gainesville I-75

Travelodge by Wyndham Gainesville

Travelodge by Wyndham Gainesville
2.5 star property
Gainesville
6.8 out of 10, (168 reviews)
"We had good staying in this hotel, it is very comfortable and clean."
United States
Alexander
$55 nightly
The price is $62
Jan 25 - Jan 26
Total with taxes and fees
Travelodge by Wyndham Gainesville

SpringHill Suites by Marriott Gainesville

SpringHill Suites by Marriott Gainesville
3.0 star property
Gainesville
8.8 out of 10, Excellent, (1,003 reviews)
"Breakfast was excellent!"
United States
michael
$93 nightly
The price is $105
Feb 8 - Feb 9
Total with taxes and fees
SpringHill Suites by Marriott Gainesville

Holiday Inn Express & Suites Gainesville I-75 by IHG

Holiday Inn Express & Suites Gainesville I-75 by IHG
2.5 star property
Gainesville
9.4 out of 10, Exceptional, (1,000 reviews)
"Wonderful stay with great amenities and friendly staff."
United States
Gina
$134 nightly
The price is $151
Jan 25 - Jan 26
Total with taxes and fees
Holiday Inn Express & Suites Gainesville I-75 by IHG

AC Hotel by Marriott Gainesville Downtown

AC Hotel by Marriott Gainesville Downtown
2.5 star property
College Park
9.0 out of 10, Wonderful, (467 reviews)
"The staff & service were great"
United States
Crystal
$147 nightly
The price is $165
Feb 8 - Feb 9
Total with taxes and fees
AC Hotel by Marriott Gainesville Downtown

Hilton University of Florida Conference Center Gainesville

Hilton University of Florida Conference Center Gainesville
3.5 star property
Gainesville
8.4 out of 10, Very Good, (1,005 reviews)
"Room was good, friendly staff and the restaurants and bar at hotel is very convenient "
United States
Sarah
$106 nightly
The price is $119
Feb 8 - Feb 9
Total with taxes and fees
Hilton University of Florida Conference Center Gainesville

Fairfield Inn & Suites by Marriott Gainesville I-75

Fairfield Inn & Suites by Marriott Gainesville I-75
2.5 star property
Gainesville
9.6 out of 10, Exceptional, (1,004 reviews)
"Great stay from check in to check out. Breakfast was very good."
United States
James
$119 nightly
The price is $134
Jan 25 - Jan 26
Total with taxes and fees
Fairfield Inn & Suites by Marriott Gainesville I-75

Home2 Suites by Hilton Gainesville Medical Center

Home2 Suites by Hilton Gainesville Medical Center
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (908 reviews)
"The property presents a calm retreat after a long day of travel. Employees of the hotel were kind and respectful and the rooms were clean and comfortable. "
United States
Cindy
$98 nightly
The price is $110
Feb 8 - Feb 9
Total with taxes and fees
Home2 Suites by Hilton Gainesville Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Fe Hotel Reviews

More cheap stays in Santa Fe

Hotels in Santa Fe with star-rating

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 18.5 mi (29.7 km) from the heart of Santa Fe, DoubleTree by Hilton Gainesville is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Hotel Eleo at the University of Florida and Hilton University of Florida Conference Center Gainesville. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best vacation rentals in Santa Fe?
The Pond House! Large Pool, 10 sleeps, Pool Table, Firepit, 10 min UF: This vacation home rental outside of Santa Fe is located on a lake and has an outdoor pool, a fireplace, and a barbecue grill to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a patio, a garden, and a selection of games so you can immerse yourself in your vacation. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
Where can I learn more about changing or cancelling my trip to Santa Fe?
To access more information about picking new dates or cancelling your trip to Santa Fe, go to https://www.expedia.com/service/.
What is staying in Santa Fe like?
Travelers to Santa Fe will find plenty to explore and enjoy. There are 728 hotels and other accommodations in the surrounding area. Find out more about Santa Fe.
What are the top places to visit in Santa Fe?
Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park, and Camp Kulaqua Conservation Easement. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Check out what more to see and do in Expedia's Santa Fe guide.
What's the seasonal weather like in Santa Fe?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 59°F. The rainiest months in Santa Fe are August, June, July, and September, with each month seeing an average of 7 inches of rainfall.

Explore a world of travel with Expedia