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Our top choices for Santa Fe hotels

Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
Starke
9.6 out of 10, Exceptional, (555 reviews)
"Clean rooms, good breakfast, pleasant staff "
United States
Anna
$118 nightly
The price is $131
Jun 14 - Jun 15
Total with taxes and fees
Holiday Inn Express Starke by IHG

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.6 out of 10, Good, (610 reviews)
"REALLY NICE PLACE, VERY CLEAN, WONDERFUL STAFF"
United States
Caroline
$65 nightly
The price is $73
May 24 - May 25
Total with taxes and fees
Palms Garden Inn

Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
Waldo
8.8 out of 10, Excellent, (1,000 reviews)
"The breakfast area was clean. Enjoyed the wide selection of food."
United States
Jeanne
$100 nightly
The price is $113
Jun 4 - Jun 5
Total with taxes and fees
Best Western Waldo Inn and Suites

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (215 reviews)
"fun getaway"
United States
Brigitte
$215 nightly
The price is $237
Jun 22 - Jun 23
Total with taxes and fees
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville
3.0 star property
Gainesville
9.6 out of 10, Exceptional, (1,461 reviews)
"Great place to stay"
United States
Barbara L
$102 nightly
The price is $115
Jun 3 - Jun 4
Total with taxes and fees
Drury Inn & Suites Gainesville

Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands
2.5 star property
Gainesville
8.8 out of 10, Excellent, (1,187 reviews)
"We had a great stay! Breakfast was good and the staff were very nice. "
United States
Christina
$78 nightly
The price is $87
Jun 15 - Jun 16
Total with taxes and fees
Sleep Inn & Suites University/Shands

Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
Lake City
9.8 out of 10, Exceptional, (18 reviews)
"Calm peaceful stay, staff was very helpful and attentive. "
United States
Patrick
$164 nightly
The price is $184
May 25 - May 26
Total with taxes and fees
Vista Verde Farm Retreat

La Quinta by Wyndham Gainesville

La Quinta by Wyndham Gainesville
3.0 star property
Gainesville
9.0 out of 10, Wonderful, (1,216 reviews)
"My favorite place to stay on my many trips to Gainsville"
United States
Joanne
$102 nightly
The price is $114
May 24 - May 25
Total with taxes and fees
La Quinta by Wyndham Gainesville

Travelodge by Wyndham Gainesville

Travelodge by Wyndham Gainesville
2.5 star property
Gainesville
7.4 out of 10, Good, (236 reviews)
"Clean room, convenient location"
United States
Aida
$55 nightly
The price is $62
Jun 14 - Jun 15
Total with taxes and fees
Travelodge by Wyndham Gainesville

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (514 reviews)
"Wonderful place to stay"
United States
Tamela
$93 nightly
The price is $104
May 31 - Jun 1
Total with taxes and fees
Hampton Inn & Suites Alachua I-75

3 Mi to UF: Townhome w/ Patio in Gainesville!

3 Mi to UF: Townhome w/ Patio in Gainesville!
3.0 star property
Gainesville
$273 nightly
The price is $304
May 27 - May 28
Total with taxes and fees
3 Mi to UF: Townhome w/ Patio in Gainesville!

Depot Village

Depot Village
2.0 star property
Gainesville
9.8 out of 10, Exceptional, (136 reviews)
"Good price, easy parking, and simply great location"
United States
CURT
$125 nightly
The price is $141
May 24 - May 25
Total with taxes and fees
Depot Village

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,000 reviews)
"Enjoyed our stay and the friendly staff! Rooms are very clean and comfortable."
United States
Mary Jayne
$91 nightly
The price is $102
Jun 21 - Jun 22
Total with taxes and fees
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Super 8 by Wyndham Gainesville I-75 Hospital University Area

Super 8 by Wyndham Gainesville I-75 Hospital University Area
2.0 star property
Gainesville
7.6 out of 10, Good, (1,002 reviews)
"Clean room, welcoming staff, location great"
United States
Jon
$54 nightly
The price is $61
May 24 - May 25
Total with taxes and fees
Super 8 by Wyndham Gainesville I-75 Hospital University Area

Gainesville Lodge

Gainesville Lodge
2.0 star property
Gainesville
8.4 out of 10, Very Good, (39 reviews)
"Great location and accommodations. "
United States
Paris
$93 nightly
The price is $104
Jun 1 - Jun 2
Total with taxes and fees
Gainesville Lodge

Comfort Suites Gainesville near University

Comfort Suites Gainesville near University
2.5 star property
Gainesville
9.0 out of 10, Wonderful, (1,346 reviews)
"Very nice and clean, good breakfast"
United States
Natalya
$93 nightly
The price is $104
Jun 14 - Jun 15
Total with taxes and fees
Comfort Suites Gainesville near University

Comfort Inn University

Comfort Inn University
2.5 star property
Gainesville
8.4 out of 10, Very Good, (1,060 reviews)
"Clean and staff was amazing the breakfast was perfect"
United States
Christina
$84 nightly
The price is $94
Jun 21 - Jun 22
Total with taxes and fees
Comfort Inn University

Best Western Gateway Grand

Best Western Gateway Grand
3.0 star property
Gainesville
8.6 out of 10, Excellent, (1,473 reviews)
"Good breakfast selection and ease of check in that allowed bigger dogs."
United States
Sara
$93 nightly
The price is $104
Jun 1 - Jun 2
Total with taxes and fees
Best Western Gateway Grand

Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
Alachua
7.2 out of 10, Good, (1,024 reviews)
"Solid hotel for the price"
United States
Michael
$74 nightly
The price is $84
Jun 11 - Jun 12
Total with taxes and fees
Quality Inn Alachua - Gainesville Area

Country Inn & Suites by Radisson, Gainesville, FL

Country Inn & Suites by Radisson, Gainesville, FL
3.0 star property
Gainesville
9.2 out of 10, Wonderful, (1,831 reviews)
"We had the best stay here. Will stay here the next time we are in town! "
United States
Elisabeth
$87 nightly
The price is $97
Jun 22 - Jun 23
Total with taxes and fees
Country Inn & Suites by Radisson, Gainesville, FL
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Top Santa Fe Hotel Reviews

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Hotels in Santa Fe with star-rating

Frequently asked questions

What's the best place for a stay in Santa Fe?
Located 18.6 mi (29.9 km) from the heart of Santa Fe, Country Inn & Suites by Radisson, Gainesville, FL is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Hilton University of Florida Conference Center Gainesville and Comfort Suites Gainesville near University. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best vacation rentals in Santa Fe?
Family-Friendly Gainesville Home - Walk to UF - Pool + Sleeps 16: This vacation home rental outside of Santa Fe offers an outdoor pool, a fireplace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. It offers a balcony, a garden, and a selection of games so you can immerse yourself in your vacation. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
Where can I learn more about changing or cancelling my trip to Santa Fe?
To access more information about picking new dates or cancelling your trip to Santa Fe, go to https://www.expedia.com/service/.
What is staying in Santa Fe like?
Travelers to Santa Fe will find plenty to explore and enjoy. There are 776 hotels and other accommodations in the surrounding area. Find out more about Santa Fe.
What are the top places to visit in Santa Fe?
Places to visit in the wider area include O'Leno State Park, San Felasco Hammock Preserve State Park, and Camp Kulaqua Conservation Easement. You'll also find Devil's Milhopper Geological State Park and Gainesville Raceway in the area. Check out what more to see and do in Expedia's Santa Fe guide.
What's the seasonal weather like in Santa Fe?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 59°F. The rainiest months in Santa Fe are August, June, July, and September, with each month seeing an average of 7 inches of rainfall.

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