Business Hotels in South Carolina from $54
Check availability on South Carolina Business Hotels
Pick from 824 South Carolina Business Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Inn Greenville - Haywood Mall
Greenville
8.0 out of 10, Very Good, (1003)
$87 nightly
The price is $96
Dec 2 - Dec 3
Total with taxes and fees

Hyatt Place Charleston Airport/Convention Center
North Charleston
9.4 out of 10, Exceptional, (1143)
$94 nightly
The price is $107
Dec 14 - Dec 15
Total with taxes and fees

Town & Country Inn and Suites
West Ashley
9.2 out of 10, Wonderful, (1522)
$149 nightly
The price is $170
Nov 26 - Nov 27
Total with taxes and fees

Sleep Inn at Greenville Convention Cente
Greenville
8.0 out of 10, Very Good, (1007)
$76 nightly
The price is $84
Nov 28 - Nov 29
Total with taxes and fees

La Quinta Inn & Suites by Wyndham Greenville Haywood
Greenville
7.4 out of 10, Good, (1120)
$65 nightly
The price is $72
Dec 14 - Dec 15
Total with taxes and fees

Home2 Suites by Hilton Greenville Downtown
Greenville Downtown
9.2 out of 10, Wonderful, (998)
$107 nightly
The price is $118
Dec 21 - Dec 22
Total with taxes and fees

Hyatt Place Greenville/Haywood
Greenville
7.8 out of 10, Good, (1016)
$80 nightly
The price is $88
Dec 8 - Dec 9
Total with taxes and fees

Sonesta Resort Hilton Head Island
South End
8.6 out of 10, Excellent, (1171)
$175 nightly
The price is $193
Nov 26 - Nov 27
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top South Carolina Hotel Reviews

Anderson Ocean Club and Spa by Oceana Resorts
10/10 Excellent
Explore a world of travel with Expedia
- Columbia Hotels
- Cheap Hotels in Columbia
- Luxury Hotels in Columbia
- Pet-friendly Hotels in Columbia
- Hotels near Downtown Columbia
- Hotels with Restaurants in Downtown Columbia
- Hotels with an Indoor Pool in Columbia
- Hotels with a View in Downtown Columbia
- Hotels with Free Breakfast in Downtown Columbia
- Hotels with Connecting Rooms in Downtown Columbia
- Historic Hotels in Downtown Columbia
- Hotels with Room Service in Downtown Columbia
- Hotels with Hot Tubs in Downtown Columbia
- Hotels with Suites in Downtown Columbia
- Luxury Hotels in Downtown Columbia
- Hotels with Bars in Downtown Columbia
- Pet-friendly Hotels in Downtown Columbia
- Hotels with an Outdoor Pool in Downtown Columbia
- Hotels with Free Parking in Downtown Columbia
- Hotels with a Gym in Downtown Columbia
- Hotels with Kitchenettes in Downtown Columbia
- Hotels with an Indoor Pool in Downtown Columbia
- Hotels with Balconies in Downtown Columbia
- Hotels with Laundry Facilities in Downtown Columbia
- Resorts & Hotels with Spas in Downtown Columbia
- Honeymoon Resorts & in Downtown Columbia
- Hotel Wedding Venues Hotels in Downtown Columbia
- Hotels with a Pool in Downtown Columbia
- Cheap Hotels in Downtown Columbia
- Hotels with Suites in Columbia
- Hotels with Balconies in Columbia
- Hotels with Hot Tubs in Columbia
- Resorts & Hotels with Spas in Columbia
- Hotels with Free Airport Shuttle in Columbia
- Hotels with smoking rooms in Columbia
- Hotels with Connecting Rooms in Columbia
- Honeymoon Resorts & in Columbia
- Hotels with Kitchenettes in Columbia
- Boutique Hotels in Columbia
- Hotels with Early Check-in in Columbia
- Hotel Wedding Venues Hotels in Columbia
- Hotels with Bars in Columbia
- Hotels with Restaurants in Columbia
- Hotels with Free Breakfast in Columbia
- Hotels with a Gym in Columbia
- Beach Hotels in Columbia
- Romantic Hotels in Columbia
- Hotels with an Outdoor Pool in Columbia
- Casino Hotels in Columbia
- Hotels with an Indoor Pool in The Vista
- Hotels with Free Parking in The Vista
- Luxury Hotels in The Vista
- Hotels with an Outdoor Pool in The Vista
- Hotel Wedding Venues Hotels in The Vista
- Extended Stay Hotels in Columbia
- Family Hotels in Columbia
- Historic Hotels in Columbia
- Adults Only Resorts & in Columbia
- Hotels with Room Service in Columbia
- Hotels on the Lake in Columbia
- Golf Hotels in Columbia
- Hotels with Laundry Facilities in Columbia
- Hotels with Free Parking in Columbia
- Hotels with a Pool in Columbia
- Hotels with Fireplaces in Columbia
- Business Hotels in Columbia
- Hotels with a View in Columbia
- Non-Smoking Hotels in Columbia
- Quiet Resorts & in Columbia
- Hotels with Tennis Courts in Columbia
- Hotels & Resorts for Couples in Columbia
- Hotel with a Concierge Hotels in Columbia
- Hotels with Air Conditioning in Columbia
- Green Hotels in Columbia
- Fishing Resorts & in Columbia
- Hotels near University of South Carolina
- 5 Star Hotels in Downtown Columbia
- 3 Star Hotels in Downtown Columbia
- Hotels near South Carolina State House
- Hotels near Trinity Episcopal Cathedral
- Hotels near Town Theatre
- Hotels near Colonial Life Arena
- Motels in Columbia
- Hotels near Columbia Metropolitan Convention Center
- The Vista Hotels
- 5 Star Hotels in Columbia


















































