Find hotels in Matlacha Isles, Cape Coral

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Discover Matlacha Isles hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4.0 star property
10.7 mi from Matlacha Isles
8.4 out of 10, Very Good, (1010)
"This was thr best place that we have ever stayed at. "
United States
Matthew
$221 nightly
The price is $247
Nov 30 - Dec 1
Total with taxes and fees
Marriott Sanibel Harbour Resort & Spa
Interior entrance
Allure Suites

Allure Suites

3.0 star property
10.5 mi from Matlacha Isles
7.6 out of 10, Good, (1008)
"Was clean staff was very nice"
United States
Richard J
$55 nightly
The price is $62
Nov 23 - Nov 24
Total with taxes and fees
Allure Suites
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

3.0 star property
11.3 mi from Matlacha Isles
8.6 out of 10, Excellent, (1003)
"Clean room, wonderful staff, and nice breakfast. "
United States
Danielle
$95 nightly
The price is $106
Dec 1 - Dec 2
Total with taxes and fees
Residence Inn by Marriott Fort Myers Sanibel
Property amenity
Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75

2.5 star property
15.4 mi from Matlacha Isles
9.6 out of 10, Exceptional, (331)
"Friendly staff, great breakfast, clean room. "
United States
Shellie
$96 nightly
The price is $107
Nov 30 - Dec 1
Total with taxes and fees
Comfort Suites Fort Myers East I-75
Lobby
Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites

2.5 star property
12.9 mi from Matlacha Isles
8.8 out of 10, Excellent, (1081)
"Service was great, cleanliness was good ad well, really enjoyed breakfast"
United States
Tina
$71 nightly
The price is $79
Nov 23 - Nov 24
Total with taxes and fees
Best Western Fort Myers Inn & Suites
Lobby
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2.0 star property
17.4 mi from Matlacha Isles
8.0 out of 10, Very Good, (1489)
"Clean, comfortable and quiet facility… I would stay here again!"
United States
John
$69 nightly
The price is $77
Nov 23 - Nov 24
Total with taxes and fees
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Laptop workspace, blackout drapes, free WiFi, bed sheets
StudioRes Fort Myers Airport

StudioRes Fort Myers Airport

3.0 star property
18.4 mi from Matlacha Isles
8.2 out of 10, Very Good, (11)
"Clean room, staff, amenities, easy check in, easy access to gas stations, restaurants, and retail. "
United States
Gina
$80 nightly
The price is $89
Nov 30 - Dec 1
Total with taxes and fees
StudioRes Fort Myers Airport
Hypo-allergenic bedding, down comforters, individually decorated
Econo Lodge Fort Myers North

Econo Lodge Fort Myers North

2.0 star property
Hancock, 10.3 mi from Matlacha Isles
5.6 out of 10, (296)
"Friendly staff great location close to beaches for a reasonable price"
United States
John
$63 nightly
The price is $70
Dec 6 - Dec 7
Total with taxes and fees
Econo Lodge Fort Myers North
Outdoor pool
Days Inn by Wyndham Fort Myers Springs Resort

Days Inn by Wyndham Fort Myers Springs Resort

2.5 star property
17.4 mi from Matlacha Isles
6.0 out of 10, (1000)
"It was a really clean hotel "
United States
Tina
$64 nightly
The price is $71
Nov 23 - Nov 24
Total with taxes and fees
Days Inn by Wyndham Fort Myers Springs Resort
Deluxe Studio, 1 King Bed, Marina View | View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 star property
12.7 mi from Matlacha Isles
8.8 out of 10, Excellent, (1005)
"Great Place to Stay!"
United States
JUDY
$98 nightly
The price is $110
Nov 23 - Nov 24
Total with taxes and fees
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Exterior
Best Western Fort Myers Waterfront

Best Western Fort Myers Waterfront

3.0 star property
Hancock, 10.3 mi from Matlacha Isles
7.4 out of 10, Good, (1005)
"Great hospitality. Perfect view on the water. Great restaurant on site and IHOP next door. "
United States
Carol
$101 nightly
The price is $113
Nov 23 - Nov 24
Total with taxes and fees
Best Western Fort Myers Waterfront
Garden
Travelodge by Wyndham Fort Myers North

Travelodge by Wyndham Fort Myers North

2.0 star property
Hancock, 10.2 mi from Matlacha Isles
5.8 out of 10, (1001)
"Great place to stay "
United States
Blaine
$49 nightly
The price is $55
Nov 30 - Dec 1
Total with taxes and fees
Travelodge by Wyndham Fort Myers North
Outdoor pool
Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd

2.5 star property
13 mi from Matlacha Isles
9.4 out of 10, Exceptional, (1001)
"Clean room, friendly staff, nice breakfast"
United States
Mercedes
$111 nightly
The price is $124
Dec 14 - Dec 15
Total with taxes and fees
Hampton Inn & Suites Fort Myers - Colonial Blvd
View from room
Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral

3.0 star property
12.7 mi from Matlacha Isles
8.2 out of 10, Very Good, (1005)
"Was a terrific stay and they went out of their way to accommodate my injured dog even giving us a late checkout "
United States
laura
$79 nightly
The price is $88
Dec 22 - Dec 23
Total with taxes and fees
Courtyard by Marriott Fort Myers Cape Coral
Exterior
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

3.0 star property
11.4 mi from Matlacha Isles
8.0 out of 10, Very Good, (1006)
"Great place to stay and breakfast was delicious "
United States
Keishly
$101 nightly
The price is $113
Nov 23 - Nov 24
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Interior entrance
Candlewood Suites Ft Myers I-75 by IHG

Candlewood Suites Ft Myers I-75 by IHG

2.5 star property
15.6 mi from Matlacha Isles
8.0 out of 10, Very Good, (741)
"The suite is equipped with everything you need."
United States
Elizabet
$69 nightly
The price is $77
Nov 30 - Dec 1
Total with taxes and fees
Candlewood Suites Ft Myers I-75 by IHG
Pool
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

3.5 star property
11.1 mi from Matlacha Isles
8.6 out of 10, Excellent, (832)
"Staff was friendly. "
United States
Jennifer
$139 nightly
The price is $155
Dec 1 - Dec 2
Total with taxes and fees
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
Exterior
Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum

3.0 star property
15.4 mi from Matlacha Isles
8.2 out of 10, Very Good, (1008)
"Goodlocation"
United States
Mary Michael
$93 nightly
The price is $103
Nov 25 - Nov 26
Total with taxes and fees
Hyatt Place Fort Myers/at The Forum
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.5 star property
12.4 mi from Matlacha Isles
9.4 out of 10, Exceptional, (1012)
"Excellent room and price! Breakfast was great. Holiday Inn Express is doing everything right for a comfortable stay."
United States
Denise
$79 nightly
The price is $88
Nov 25 - Nov 26
Total with taxes and fees
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Property amenity
MainStay Suites Fort Myers East I-75

MainStay Suites Fort Myers East I-75

2.5 star property
15.4 mi from Matlacha Isles
9.6 out of 10, Exceptional, (204)
"Overall good hotel for a reasonable price "
United States
Carolyn
$94 nightly
The price is $104
Nov 29 - Nov 30
Total with taxes and fees
MainStay Suites Fort Myers East I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most.

Pelican

If you're spending some time in Pelican, Tarpon Point and Harbour View Gallery are top sights worth seeing.

Cape Coral which includes a river or creek and a park

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Mariner

While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

North Fort Myers showing a sandy beach, general coastal views and a coastal town

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

Yacht Club

While there might not be top attractions in Yacht Club, you can explore the larger area and discover places like Cape Coral Yacht Club Beach and Dolphin Marina.

Top Matlacha Isles Hotel Reviews

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

10/10 Excellent
"Great and clean room. The front desk people were very nice friendly and helpful the restaurant was good and the coffee shop and the beach maintenance was superb."
Rebecca 3-night trip
Posted 1 day ago
Lani Kai Beachfront Resort

Frequently asked questions

What is Matlacha Isles like?
Travelers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighborhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to kick up your feet after a day of exploring the sights in Cape Coral, you can choose from 16 Expedia hotels and other accommodations in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, you'll find most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available in Matlacha Isles.
Where can I learn more about changing or cancelling my trip to Matlacha Isles?
To find more details about changing or cancelling your trip to Matlacha Isles, go to https://www.expedia.com/service/.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens, and Royal Tee Golf Club. While you're out sightseeing in Cape Coral, be sure to visit other sights like Little Dead Key or Big Dead Key.

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