Find hotels in Otay Mesa, San Diego from $87

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Discover 4,664 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Otay Mesa hotels

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1078)
"Prefect stay with the family. Would stay again and recommend to friends. "
$132 nightly
The price is $145
Sep 15 - Sep 16
Total with taxes and fees
Ayres Hotel San Diego South - Chula Vista

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1519)
"Love this place"
$138 nightly
The price is $151
Sep 18 - Sep 19
Total with taxes and fees
Sycuan Casino Resort

Sea Harbor Hotel

2.0 star property
8.4 out of 10, Very Good, (954)
"Good property for a few nights before your get on your boat for a fishing trip! "
$108 nightly
The price is $122
Sep 1 - Sep 2
Total with taxes and fees
Sea Harbor Hotel

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
8.0 out of 10, Very Good, (1455)
"Very good to stayed "
$131 nightly
The price is $149
Sep 6 - Sep 7
Total with taxes and fees
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1009)
"Nice place. Clean and quiet. "
$108 nightly
The price is $122
Sep 21 - Sep 22
Total with taxes and fees
Quality Suites San Diego Otay Mesa

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (423)
"Nice pool and decent breakfast"
$137 nightly
The price is $151
Sep 7 - Sep 8
Total with taxes and fees
SpringHill Suites by Marriott Chula Vista Eastlake

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1249)
"We will definitely be staying there again"
$154 nightly
The price is $173
Sep 1 - Sep 2
Total with taxes and fees
Lamplighter Inn & Suites at SDSU

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1394)
"Great place to stay at , along with a good breakfast variety. Overall I'll stay here again"
$105 nightly
The price is $116
Sep 7 - Sep 8
Total with taxes and fees
La Quinta Inn by Wyndham San Diego Chula Vista

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1142)
"Breakfast was amazing! "
$122 nightly
The price is $139
Sep 7 - Sep 8
Total with taxes and fees
Best Western Americana Inn

Hampton Inn & Suites San Diego Seaworld

2.5 star property
8.4 out of 10, Very Good, (16)
"The property was newly renovated. Clean nice decor. Love the furniture "
$118 nightly
The price is $136
Sep 7 - Sep 8
Total with taxes and fees
Hampton Inn & Suites San Diego Seaworld

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1025)
"It was a lovely stay. "
$240 nightly
The price is $266
Sep 1 - Sep 2
Total with taxes and fees
Loews Coronado Bay Resort

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3260)
"Good place to stay"
$125 nightly
The price is $138
Sep 7 - Sep 8
Total with taxes and fees
Best Western Plus Marina Gateway Hotel

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1285)
"Excellent hotel !! "
$89 nightly
The price is $102
Sep 1 - Sep 2
Total with taxes and fees
Best Western San Diego Pacific Beach/Mission Bay

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (1109)
"everyone was lovely the ambience is everything, definitely coming back. "
$226 nightly
The price is $259
Sep 22 - Sep 23
Total with taxes and fees
Lafayette Hotel & Club

Best Western Yacht Harbor Hotel

2.5 star property
8.6 out of 10, Excellent, (1537)
"Great location, not too expensive!"
$100 nightly
The price is $115
Sep 1 - Sep 2
Total with taxes and fees
Best Western Yacht Harbor Hotel

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1491)
"Clean, great staff. "
$110 nightly
The price is $121
Sep 7 - Sep 8
Total with taxes and fees
Best Western Chula Vista/Otay Valley Hotel

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (964)
"Great location within walking distance from the places we wanted to visit."
$99 nightly
The price is $112
Sep 1 - Sep 2
Total with taxes and fees
Berkshire Motor Hotel

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2879)
"Beautiful Hotel"
$146 nightly
The price is $168
Sep 21 - Sep 22
Total with taxes and fees
Legacy Resort Hotel & Spa

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (331)
"Great place to stay!"
$159 nightly
The price is $184
Sep 1 - Sep 2
Total with taxes and fees
Sentral Gaslamp Quarter

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1011)
"Great hotel "
$76 nightly
The price is $87
Sep 1 - Sep 2
Total with taxes and fees
Valli Hi Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa Hotel Reviews

Find out more about Otay Mesa

Find out more about Otay Mesa

Top reasons to visit Otay Mesa

  • Diverse Accommodations: Otay Mesa offers a wide range of lodging options, from budget-friendly hotels to luxurious stays, catering to every traveler's needs.
  • Family-Friendly Activities: The area is perfect for families, with numerous parks and entertainment options suitable for all ages.
  • Cultural Experiences: Explore vibrant neighborhoods filled with local art, friendly locals, and cultural attractions.
  • Stunning Sunsets: Enjoy breathtaking sunsets that create a picturesque backdrop for your vacation.
  • Shopping and Entertainment: Visit local shopping centers and catch a show at nearby theaters for a fun-filled experience.

Find great hotels near Otay Mesa

Otay Mesa is an ideal destination for travelers seeking diverse hotel accommodations, from budget-friendly options to luxurious stays. With a variety of lodging types, including hotels and aparthotels, you'll find facilities tailored to business and adventure themes. Whether you're looking for the best hotels, competitive room rates, or convenient access to San Diego's attractions, Otay Mesa has something for everyone to ensure a memorable vacation experience.

  • Wyndham San Diego Bayside: Nestled 16 miles from Otay Mesa, the Wyndham San Diego Bayside is a 4-star hotel that caters to adventure seekers, families, and business travelers alike. This property boasts a variety of exciting recreational activities such as sailing, boat tours, and parasailing nearby. Business guests will appreciate the extensive meeting facilities, including a conference center and accessible business center. Families are well taken care of with free cribs and amenities designed for children, making it a perfect choice for a fun-filled getaway.
  • Wyndham Garden San Diego Near SeaWorld: Located 19 miles from Otay Mesa, this 3-star hotel is ideal for business travelers seeking convenience and comfort. The Wyndham Garden San Diego Near SeaWorld offers essential business amenities, including a well-equipped meeting room and business center. While focused on business needs, the hotel is also a great spot for those wanting to explore nearby attractions, including the famous SeaWorld, ensuring a balanced experience of work and leisure.
  • Manchester Grand Hyatt San Diego: Just 15 miles from Otay Mesa, the Manchester Grand Hyatt San Diego is a luxurious 4-star hotel that excels in providing adventure, family fun, and business facilities. Guests can indulge in various outdoor activities like kayaking and windsurfing nearby. The hotel features multiple meeting rooms and accessible business amenities, catering to corporate needs. Additionally, family-friendly services ensure that children have a memorable stay, making it a versatile choice for all types of travelers.

Discover the best areas to stay near Otay Mesa

Otay Mesa offers a unique blend of family-friendly activities, cultural experiences, and business opportunities. Visitors can explore vibrant neighborhoods filled with friendly locals, art, and beautiful scenery. Don't miss the breathtaking sunsets that paint the sky with stunning colors, creating the perfect backdrop for a memorable vacation. Whether you're here for leisure or work, Otay Mesa promises a diverse and enriching travel experience.

  • San Diego: San Diego is a vibrant city that serves as the backdrop for your Otay Mesa adventure. Known for its diverse attractions, visitors flock to this sun-soaked locale year-round, with peak seasons occurring in March to April and July. Families and outdoor enthusiasts will find plenty to do, from enjoying stunning beaches to exploring theme parks. The city boasts a variety of shopping centers and casinos, ensuring there's always something to keep you entertained. Don’t miss the chance to visit the iconic family-friendly beaches and savor the local cuisine at waterfront restaurants.
  • Ocean View Hills: Located just 3 miles from Otay Mesa, Ocean View Hills is a charming neighborhood perfect for family outings and romantic getaways. The area enjoys a steady flow of visitors, particularly in April and during the summer months. Here, you can catch a show at the local theater or indulge in some retail therapy at the nearby shopping malls. The proximity to beaches and theme parks adds to its allure, making it an ideal spot for those looking to unwind or create lasting memories with loved ones.
  • San Ysidro: A short 4 miles from Otay Mesa, San Ysidro is a bustling city known for its family-friendly atmosphere and city vibes. It attracts visitors year-round, especially during the summer and holiday seasons. Shopping enthusiasts will love the numerous shopping centers and theaters that dot the landscape. Additionally, you can explore local landmarks and enjoy the nearby beaches, making San Ysidro a great destination for both leisure and business travelers alike.

Things to do near Otay Mesa

Otay Mesa in San Diego is a great destination for families, business travelers, and entertainment seekers. Visitors can enjoy a variety of activities, including shopping at local centers and malls, as well as catching a show at nearby theaters. With its vibrant atmosphere, Otay Mesa offers a mix of leisure and fun for everyone.

Food and drinks

For a local food experience in Otay Mesa, check out IHOP for a classic breakfast. Don't miss street tacos from nearby vendors for an authentic taste of San Diego. If you're in the mood for drinks, Bay City Brewing Co. offers a great selection of craft beers.

Shopping

For shopping in Otay Mesa, visit Las Americas Premium Outlets, just 4 miles away, featuring a range of brands. Chula Vista Center is another option, located 8 miles from Otay Mesa, offering a family-friendly atmosphere. If you're up for a drive, Taylor Guitars is 18 miles away.

Recreation

At Petco Park, immerse yourself in the thrilling sports atmosphere while enjoying a game. Eastlake Country Club offers a serene golf experience amidst beautiful landscapes. The Salvation Army Kroc Center provides luxurious amenities for relaxation and wellness, making it an ideal spot for rejuvenation.

Adventure

At Sky Zone San Diego Indoor Trampoline Park, located 7 miles from Otay Mesa, you can experience the thrill of bouncing on trampolines, engaging in dodgeball, and enjoying a fun-filled day with friends and family in an energetic atmosphere.

Nightlife

Experience the vibrant nightlife at North Island Credit Union Amphitheatre, just 3 miles from Otay Mesa, where you can enjoy live performances. For a thrill, visit Len Moore Skate Park, 5 miles away, offering arcade fun for the whole family. Don’t miss the excitement at Sycuan Casino, 18 miles from Otay Mesa.

Booking tips and Expedia advantages for Otay Mesa

To save money during your visit to Otay Mesa, consider exploring free attractions like Las Americas Premium Outlets, San Diego Bay, and Silver Strand State Beach. The best times to visit for lower prices are from November to January. Booking your hotel about a month in advance or checking last-minute deals on Expedia can lead to great savings. Be sure to filter prices from lowest to highest and consider bundling your hotel, flights, and activities for additional discounts. Joining Expedia's One Key membership can also unlock exclusive deals and future savings.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Otay Mesa are November to January, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher.
  • The best time to book a hotel: The cheapest time to book a hotel around Otay Mesa is usually 1 month out from when you are planning to stay. If you're a little more spontaneous, you could also peruse Expedia's last minute deals which could secure you a cheaper stay. Look out for the green banner below the price to spot the deals.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your choices based on your budget, desired location, and preferred hotel type. To find the best prices and deals, arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Otay Mesa hotel reservation with your flights and activities when you book an Expedia package.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near Otay Mesa

Otay Mesa offers a blend of family-friendly activities, entertainment, and business opportunities. Visitors can explore beautiful beaches, urban parks, and modern colleges or universities. This vibrant area caters to those seeking cultural experiences and outdoor adventures, making it perfect for families. Don't miss nearby attractions like Point Loma and consider using a San Diego guide to enhance your visit and discover the best local highlights.

  • San Ysidro Border Crossing: Experience the bustling atmosphere of one of the busiest border crossings in the world. With a unique blend of cultures, it's a great spot for family-friendly activities and local eateries, all under sunny skies.
  • San Diego Convention Center: Ideal for business travelers and event-goers, this modern venue hosts a variety of conferences and exhibitions. Its impressive architecture and waterfront views make it a remarkable place to connect and network.
  • Balboa Park: Stroll through this expansive cultural hub featuring stunning gardens, museums, and art installations. Balboa Park is a perfect blend of nature and creativity, providing a serene escape amidst urban life.

Best time to go to Otay Mesa

Visitor numbers around Otay Mesa is generally unchanged in popularity throughout the year. The best time to visit Otay Mesa is dependant on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are average and weather is sunny with no rain. February is its coolest month on average. At this time, visitor numbers are average and weather is sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January57.4°F (14.1°C)Light RainSunnySlightly LowSlightly Low
February56.8°F (13.8°C)Light RainSunnyAverageAverage
March58.1°F (14.5°C)No Rain (Dry)Mostly SunnyAverageAverage
April60.6°F (15.9°C)No Rain (Dry)SunnyAverageAverage
May62.6°F (17.0°C)No Rain (Dry)SunnyAverageAverage
June66.4°F (19.1°C)No Rain (Dry)SunnySlightly HighSlightly High
July70.5°F (21.4°C)No Rain (Dry)SunnySlightly HighSlightly High
August72.3°F (22.4°C)No Rain (Dry)SunnyAverageSlightly High
September72.0°F (22.2°C)No Rain (Dry)SunnySlightly HighAverage
October68.2°F (20.1°C)No Rain (Dry)SunnySlightly LowAverage
November62.6°F (17.0°C)No Rain (Dry)SunnyAverageSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Otay Mesa

Traveling to Otay Mesa, San Diego, is convenient with access to two major airports. San Diego International Airport (SAN) is located 18 miles away and offers luxury accommodations such as Pendry San Diego and THE US GRANT, both 3 and 2 miles from the airport, respectively. Another option is Tijuana International Airport (TIJ), just 0.9 miles from Otay Mesa, with nearby hotels like Real Inn Tijuana and Hotel Lucerna Tijuana, both around 3 miles from the airport. Gillespie Field (SEE), also 18 miles away, has hotels like Sycuan Casino Resort and Sheraton Mission Valley San Diego Hotel within a short drive, ensuring easy access to your travel needs.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What are the best family hotels in Otay Mesa?
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is an excellent choice for families seeking comfort and convenience during their stay. This hotel offers thoughtfully designed rooms with connecting options, ensuring that families can stay close together. With amenities like free cribs and sofa beds, you can rest easy knowing that your little ones will have a cozy place to sleep at night. Guests appreciate the daily housekeeping, which provides a straightforward experience, and the complimentary buffet breakfast, superb for fueling up before a day of adventure.

Another family-friendly option in Otay Mesa is Quality Suites San Diego Otay Mesa. Rated 7.2 by travelers, this hotel features a refreshing pool where kids can splash and play, making it a great place to unwind after a busy day. The hotel's connecting rooms and child-friendly window designs prioritize safety and comfort, ensuring that both parents and children feel at home. Additionally, the provision of free amenities for children adds extra value, making it easier for families to enjoy their stay without worrying about additional costs.
What are the best spa hotels in Otay Mesa?
For a comfortable stay in Otay Mesa, the Quality Suites San Diego Otay Mesa is a solid choice, holding a review score of 7.2. This hotel provides accessible spa amenities, allowing guests to unwind and rejuvenate during their visit.
What hotels in Otay Mesa offer free breakfast?
The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is a great choice for travelers seeking convenience and comfort. This family-friendly hotel not only offers free breakfast, including a delicious buffet, but also features spacious suites equipped with a sofa bed, making it easy to accommodate families of all sizes. Guests appreciate the outdoor pool, great for unwinding after a day of exploring, along with complimentary amenities such as toiletries, WiFi, and self-parking. With a customer review rating of 7.8, it's clear that families find value in the quality service and facilities provided.

Another option in Otay Mesa is the Quality Suites San Diego Otay Mesa, which also offers a complimentary breakfast to start your day right. This hotel features an outdoor pool and hot tub, ideal for relaxation and family fun. The Quality Suites is particularly appealing for those requiring accessible parking and facilities, and with a review score of 7.2, it provides a comfortable experience for guests looking for extra conveniences.
What are the best budget hotels in Otay Mesa?
The Holiday Inn Express Hotel & Suites San Diego Otay Mesa is an excellent budget-friendly option, boasting a review score of 7.8. Families will appreciate the complimentary buffet breakfast, which makes mornings easy, and the outdoor pool is superb for a refreshing dip after a day of adventures. With free Wi-Fi and spacious suites featuring sofa beds, this hotel ensures everyone has enough room to relax. Plus, the availability of cribs and rollaway beds at no extra charge makes it convenient for families traveling with little ones.

Another great choice for budget-conscious travelers is the Quality Suites San Diego Otay Mesa, which has a review score of 7.2. This hotel offers a range of amenities geared towards families, including a free breakfast and outdoor pool, which is sure to keep kids entertained. The rooms are designed with child-friendly window features, providing peace of mind for parents. Self-parking is complimentary as well, making it easy for families to explore the local area without worrying about extra fees.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Otay Mesa.
How can I save on a Otay Mesa hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Otay Mesa hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Otay Mesa hotel?
Hotel prices in Otay Mesa often vary, but you can find a great deal from $87 on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.