Find hotels in Otay Mesa, San Diego from $108

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Discover 4,664 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Otay Mesa hotels

Ayres Hotel San Diego South - Chula Vista

3.0 star property
9.8 out of 10, Exceptional, (1082)
"Beautiful property!! "
$132 nightly
The price is $145
Sep 15 - Sep 16
Total with taxes and fees
Ayres Hotel San Diego South - Chula Vista

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1521)
"Love this place"
$138 nightly
The price is $151
Sep 18 - Sep 19
Total with taxes and fees
Sycuan Casino Resort

Sea Harbor Hotel

2.0 star property
8.4 out of 10, Very Good, (954)
"Good property for a few nights before your get on your boat for a fishing trip! "
$119 nightly
The price is $134
Sep 3 - Sep 4
Total with taxes and fees
Sea Harbor Hotel

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
8.0 out of 10, Very Good, (1448)
"Very good to stayed "
$127 nightly
The price is $144
Sep 9 - Sep 10
Total with taxes and fees
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1013)
"Nice place. Clean and quiet. "
$108 nightly
The price is $123
Sep 21 - Sep 22
Total with taxes and fees
Quality Suites San Diego Otay Mesa

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (426)
"Customer service was wonderful for our short stay"
$137 nightly
The price is $151
Sep 7 - Sep 8
Total with taxes and fees
SpringHill Suites by Marriott Chula Vista Eastlake

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1253)
"We will definitely be staying there again"
$145 nightly
The price is $164
Sep 3 - Sep 4
Total with taxes and fees
Lamplighter Inn & Suites at SDSU

La Quinta Inn by Wyndham San Diego Chula Vista

3.0 star property
8.6 out of 10, Excellent, (1401)
"Great place to stay at , along with a good breakfast variety. Overall I'll stay here again"
$100 nightly
The price is $110
Sep 7 - Sep 8
Total with taxes and fees
La Quinta Inn by Wyndham San Diego Chula Vista

Best Western Americana Inn

2.5 star property
9.0 out of 10, Wonderful, (1146)
"Breakfast was amazing! "
$105 nightly
The price is $119
Sep 3 - Sep 4
Total with taxes and fees
Best Western Americana Inn

Hampton Inn & Suites San Diego Seaworld

2.5 star property
8.6 out of 10, Excellent, (26)
"Enjoyed our stay."
$118 nightly
The price is $136
Sep 9 - Sep 10
Total with taxes and fees
Hampton Inn & Suites San Diego Seaworld

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1031)
"Nice rooms, great staff close to beach"
$270 nightly
The price is $300
Sep 7 - Sep 8
Total with taxes and fees
Loews Coronado Bay Resort

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3276)
"Good place to stay"
$125 nightly
The price is $138
Sep 14 - Sep 15
Total with taxes and fees
Best Western Plus Marina Gateway Hotel

Best Western San Diego Pacific Beach/Mission Bay

2.5 star property
7.2 out of 10, Good, (1289)
"Friendly staff!"
$95 nightly
The price is $109
Sep 3 - Sep 4
Total with taxes and fees
Best Western San Diego Pacific Beach/Mission Bay

Lafayette Hotel & Club

4.0 star property
9.2 out of 10, Wonderful, (1119)
"I absolutely love this place! Great food and great people all around"
$226 nightly
The price is $259
Sep 22 - Sep 23
Total with taxes and fees
Lafayette Hotel & Club

Best Western Yacht Harbor Hotel

2.5 star property
8.6 out of 10, Excellent, (1539)
"Good breakfast, close to where we wanted to be and affordable."
$98 nightly
The price is $113
Sep 7 - Sep 8
Total with taxes and fees
Best Western Yacht Harbor Hotel

Best Western Chula Vista/Otay Valley Hotel

2.5 star property
7.8 out of 10, Good, (1481)
"Great hotel"
$110 nightly
The price is $121
Sep 14 - Sep 15
Total with taxes and fees
Best Western Chula Vista/Otay Valley Hotel

Berkshire Motor Hotel

2.5 star property
8.4 out of 10, Very Good, (969)
"Great location within walking distance from the places we wanted to visit."
$94 nightly
The price is $106
Sep 7 - Sep 8
Total with taxes and fees
Berkshire Motor Hotel

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2882)
"Legacy resorts was a very nice place to stay. "
$146 nightly
The price is $168
Sep 21 - Sep 22
Total with taxes and fees
Legacy Resort Hotel & Spa

Sentral Gaslamp Quarter

3.0 star property
9.2 out of 10, Wonderful, (343)
"Great place to stay!"
$159 nightly
The price is $184
Sep 21 - Sep 22
Total with taxes and fees
Sentral Gaslamp Quarter

Valli Hi Motel

2.5 star property
8.2 out of 10, Very Good, (1017)
"Great hotel "
$83 nightly
The price is $95
Sep 7 - Sep 8
Total with taxes and fees
Valli Hi Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa Hotel Reviews

Find out more about Otay Mesa

Find out more about Otay Mesa

Top reasons to visit Otay Mesa

  • Family-Friendly Activities: Otay Mesa boasts a variety of attractions perfect for families, including water parks, arcades, and theaters.
  • Shopping and Dining: Explore the Otay Town Center Mall for a mix of shopping and dining experiences.
  • Cultural Events: Attend exciting events, such as Comic-Con, that bring vibrant experiences to the area.
  • Beautiful Outdoor Spaces: Nearby Mission Bay offers stunning scenery and outdoor adventures for nature lovers.
  • Diverse Accommodations: Choose from a wide range of hotels suitable for business, families, and pets.

Find great hotels near Otay Mesa

Discover a variety of hotel accommodations in Otay Mesa, San Diego, designed to meet the needs of every traveler. Whether you're seeking a business-friendly environment, a pet-friendly stay, or a family vacation experience, you'll find plenty of options. From budget-friendly choices to top-rated hotels, Otay Mesa offers a diverse selection of lodging with essential amenities and positive reviews to ensure a comfortable and enjoyable visit.

  • Best Western Plus Marina Gateway Hotel: Nestled 11 miles from Otay Mesa, the Best Western Plus Marina Gateway Hotel offers a unique eco-friendly retreat for conscientious travelers. This hotel is eco-certified and welcomes pets, making it a perfect choice for those traveling with furry companions. The property is inclusive and LGBTQIA-friendly, ensuring that everyone feels at home. Guests can enjoy comfortable accommodations that emphasize sustainability without sacrificing style, allowing you to relax after a day of exploration.
  • Ramada by Wyndham San Diego National City: Located 11 miles away from Otay Mesa, the Ramada by Wyndham San Diego National City is an excellent choice for families and adventure-seekers alike. This 3-star hotel features a robust business center, making it ideal for corporate travelers. For those in search of excitement, nearby adventure sports such as snorkeling, parasailing, and surfing are readily available. The hotel also offers family-friendly amenities, including complimentary cribs, ensuring a comfortable stay for guests of all ages.
  • Hard Rock Hotel San Diego: Situated 15 miles from Otay Mesa, the Hard Rock Hotel San Diego delivers an exhilarating experience for those craving adventure and vibrant nightlife. This 4-star hotel is LGBTQIA-friendly and provides a myriad of recreational activities such as waterskiing, biking, and skydiving nearby. Guests will enjoy the rock-and-roll ambiance, luxurious accommodations, and a lively atmosphere that keeps the energy high. Whether you're looking to relax or take on new adventures, this hotel is the perfect backdrop for an unforgettable stay.

Where to stay near Otay Mesa

Otay Mesa offers a vibrant mix of family-friendly attractions and cultural experiences. Explore the Otay Town Center Mall for shopping and dining, or venture to nearby Mission Bay for beautiful scenery and outdoor activities. A short drive will take you to Point Loma, where you can enjoy stunning views and romantic strolls. With its welcoming atmosphere and diverse options, Otay Mesa is an excellent base for your San Diego adventure.

  • San Diego: As a vibrant city, San Diego is a hub of activity and culture, perfectly situated near Otay Mesa. With year-round pleasant weather, it attracts visitors for its family-friendly atmosphere, outdoor adventures, and stunning beaches. From world-renowned theme parks to beautiful family beaches, there's something for everyone. Enjoy shopping at local centers or relax at resorts, making San Diego an ideal base for exploration. The city experiences peak tourist seasons from March to April and July, providing a lively atmosphere filled with events and activities.
  • Ocean View Hills: A charming neighborhood located 3 miles from Otay Mesa, Ocean View Hills offers a family-oriented environment with a touch of entertainment flair. Visitors are drawn here for romantic outings and fun adventures, especially during peak months in April and July through August. Explore local theaters and shopping malls, or enjoy a day at the nearby theme parks and beaches. The neighborhood's welcoming vibe and accessible amenities make it a delightful stop for those seeking a unique blend of relaxation and entertainment.
  • San Ysidro: Just 4 miles from Otay Mesa, San Ysidro is a bustling city known for its diverse experiences. Popular among families and business travelers alike, the city sees an influx of visitors during June to July and November. The vibrant shopping centers and theaters offer plenty of entertainment options, while local attractions include a symbolic landmark and beautiful beaches. San Ysidro's accessibility to various amenities makes it a perfect destination for those looking to immerse themselves in the local culture and enjoy a lively city atmosphere.

Things to do near Otay Mesa

Otay Mesa is a fantastic destination for family-oriented and entertainment-themed vacations. Enjoy a variety of activities such as shopping at local centers and malls, catching a show at the theater, or having fun at an arcade. For memorable family outings, consider visiting a nearby water park or attending events like Comic-Con, ensuring a delightful and exciting stay for everyone.

Shopping

For shopping in Otay Mesa, visit Las Americas Premium Outlets, 4 miles away, offering a vibrant mix of entertainment and family-friendly options. Otay Ranch Town Center, also 4 miles away, features a range of shops in a bustling city atmosphere. Chula Vista Center, 8 miles away, adds more entertainment and shopping choices.

Recreation

At the Chula Vista Elite Athlete Training Center, immerse yourself in a vibrant sports atmosphere while engaging in various athletic activities. For a serene outdoor experience, visit Eastlake Country Club for golf amidst beautiful landscapes. Lastly, Mount Helix Park offers peaceful trails perfect for relaxation and wellness.

Adventure

At Sesame Place San Diego, located 3 miles from Otay Mesa, enjoy thrilling water attractions and family-friendly entertainment. Nearby, White Water Canyon offers a similar experience with exciting rides and water fun for all ages. For an energetic twist, visit Sky Zone San Diego Indoor Trampoline Park, 7 miles away, for exhilarating bouncing adventures.

Nightlife

In Otay Mesa, the North Island Credit Union Amphitheatre offers a vibrant atmosphere with live performances, perfect for a night out. For a fun twist, head to Len Moore Skate Park or Atlantis Laser Tag, both providing adventurous arcade experiences just a short drive away.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Otay Mesa

To save money during your visit to Otay Mesa, consider traveling between November and January when accommodation prices are lower. Book your stay on a Tuesday for the best rates, and avoid Saturdays for higher costs. Use Expedia to find customized hotel options and take advantage of package deals that combine flights and activities for additional savings. Join the One Key membership for exclusive discounts and earn OneKeyCash for future stays. Lastly, explore free local attractions and utilize public transport to keep costs down while enjoying the area.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Otay Mesa are November to January, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Otay Mesa is Tuesday. The most expensive day to stay around Otay Mesa is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to customize your preferences, such as your budget, preferred location, and the type of hotel you’re looking for. To find the best prices and deals, be sure to sort the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your Otay Mesa hotel reservation with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near Otay Mesa

Otay Mesa offers a vibrant mix of family-friendly and entertainment-themed activities, making it an ideal vacation spot. Visitors can enjoy the beautiful nearby beaches, explore urban parks, or attend events at local conference venues. The area's attractions provide a rich cultural experience and opportunities for outdoor adventures, perfect for families looking to create lasting memories while discovering the charm of this San Diego neighborhood.

  • San Ysidro Border Crossing: Experience the bustling energy of the San Ysidro Border Crossing, located a mere 3 miles from Otay Mesa. This vibrant civic area is perfect for families and business travelers alike, offering friendly interactions and bright, sunny weather that enhances your visit.
  • San Diego Convention Center: Situated 15 miles away, the San Diego Convention Center serves as a premier event and conference venue. It’s a hub for business activities and networking, showcasing the city's commitment to hosting world-class events.
  • Coronado Beach: Also 15 miles from Otay Mesa, Coronado Beach is an idyllic spot for sunbathing and relaxation. With its soft sands and inviting waves, it embodies the quintessential beach vibes of Southern California.

Best time to go to Otay Mesa

The best time to visit Otay Mesa is dependent on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are average and weather is sunny with no rain. February is its coolest month on average. At this time, visitor numbers are average and weather is sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January57.4°F (14.1°C)Light RainSunnySlightly LowSlightly Low
February56.8°F (13.8°C)Light RainSunnyAverageAverage
March58.1°F (14.5°C)No RainMostly SunnyAverageAverage
April60.6°F (15.9°C)No RainSunnyAverageAverage
May62.6°F (17.0°C)No RainSunnyAverageAverage
June66.4°F (19.1°C)No RainSunnySlightly HighSlightly High
July70.5°F (21.4°C)No RainSunnySlightly HighSlightly High
August72.3°F (22.4°C)No RainSunnyAverageSlightly High
September72.0°F (22.2°C)No RainSunnySlightly HighAverage
October68.2°F (20.1°C)No RainSunnySlightly LowAverage
November62.6°F (17.0°C)No RainSunnyAverageSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Otay Mesa

When visiting Otay Mesa, San Diego, you have convenient access to several major airports. San Diego International Airport (SAN) is located 18 miles away, with excellent hotel options like the 5-star Pendry San Diego and The US Grant, both about 3 miles from the airport. Tijuana's General Abelardo L. Rodriguez International Airport (TIJ) is only 0.9 miles from Otay Mesa, with nearby accommodations including the 4.5-star Quartz Hotel & SPA. For those considering Carlsbad Airport (CLD), about 43 miles away, the luxurious Park Hyatt Aviara Resort is a great choice, situated just 2 miles from the airport. Each hotel offers easy access to the respective airports for a seamless travel experience.

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Explore a world of travel with Expedia

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What are the best family hotels in Otay Mesa?
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is an excellent choice for families seeking comfort and convenience during their stay. This hotel offers thoughtfully designed rooms with connecting options, ensuring that families can stay close together. With amenities like free cribs and sofa beds, you can rest easy knowing that your little ones will have a cozy place to sleep at night. Guests appreciate the daily housekeeping, which provides a straightforward experience, and the complimentary buffet breakfast, superb for fueling up before a day of adventure.

Another family-friendly option in Otay Mesa is Quality Suites San Diego Otay Mesa. Rated 7.2 by travelers, this hotel features a refreshing pool where kids can splash and play, making it a great place to unwind after a busy day. The hotel's connecting rooms and child-friendly window designs prioritize safety and comfort, ensuring that both parents and children feel at home. Additionally, the provision of free amenities for children adds extra value, making it easier for families to enjoy their stay without worrying about additional costs.
What are the best spa hotels in Otay Mesa?
For a comfortable stay in Otay Mesa, the Quality Suites San Diego Otay Mesa is a solid choice, holding a review score of 7.2. This hotel provides accessible spa amenities, allowing guests to unwind and rejuvenate during their visit.
What hotels in Otay Mesa offer free breakfast?
The Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is a great choice for travelers seeking convenience and comfort. This family-friendly hotel not only offers free breakfast, including a delicious buffet, but also features spacious suites equipped with a sofa bed, making it easy to accommodate families of all sizes. Guests appreciate the outdoor pool, great for unwinding after a day of exploring, along with complimentary amenities such as toiletries, WiFi, and self-parking. With a customer review rating of 7.8, it's clear that families find value in the quality service and facilities provided.

Another option in Otay Mesa is the Quality Suites San Diego Otay Mesa, which also offers a complimentary breakfast to start your day right. This hotel features an outdoor pool and hot tub, ideal for relaxation and family fun. The Quality Suites is particularly appealing for those requiring accessible parking and facilities, and with a review score of 7.2, it provides a comfortable experience for guests looking for extra conveniences.
What are the best budget hotels in Otay Mesa?
The Holiday Inn Express Hotel & Suites San Diego Otay Mesa is an excellent budget-friendly option, boasting a review score of 7.8. Families will appreciate the complimentary buffet breakfast, which makes mornings easy, and the outdoor pool is superb for a refreshing dip after a day of adventures. With free Wi-Fi and spacious suites featuring sofa beds, this hotel ensures everyone has enough room to relax. Plus, the availability of cribs and rollaway beds at no extra charge makes it convenient for families traveling with little ones.

Another great choice for budget-conscious travelers is the Quality Suites San Diego Otay Mesa, which has a review score of 7.2. This hotel offers a range of amenities geared towards families, including a free breakfast and outdoor pool, which is sure to keep kids entertained. The rooms are designed with child-friendly window features, providing peace of mind for parents. Self-parking is complimentary as well, making it easy for families to explore the local area without worrying about extra fees.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Otay Mesa.
How can I save on a Otay Mesa hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Otay Mesa hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Otay Mesa hotel?
Hotel prices in Otay Mesa often vary, but you can find a great deal from $108 on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.