St. Charles Vacation Rentals

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Our top choices for St. Charles vacation rentals

Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.2 out of 10, Wonderful, (43 reviews)
"House had everything we needed, and was very well organized! Would definitely recommend!"
United States
Tim W.
$449 nightly
The price is $507
Jun 7 - Jun 8
Total with taxes and fees
Charming open 4bd and screen-in porch! Sleeps 10!

Spacious 2 Bedroom Townhome

Spacious 2 Bedroom Townhome
Saint Charles
8.0 out of 10, Very Good, (16 reviews)
"This property was perfect for our needs. We enjoyed our stay and thank you for a seamless transaction! Much appreciated!"
United States
Elizabeth
$288 nightly
The price is $317
Jun 7 - Jun 8
Total with taxes and fees
Spacious 2 Bedroom Townhome

Historic 1908 Frenchtown Home

Historic 1908 Frenchtown Home
St. Charles Historic District
8.6 out of 10, Excellent, (21 reviews)
"Very clean, older 2-bedroom home. Close to all the Main Street action. House had all the amenities we needed."
United States
Michele S.
$333 nightly
The price is $366
Jun 7 - Jun 8
Total with taxes and fees
Historic 1908 Frenchtown Home

St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres

St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres
Saint Charles
8.8 out of 10, Excellent, (3 reviews)
"We loved the location for our travel needs and we had everything we needed for a family of two adults and two dogs. "
United States
Leslie R.
$500 nightly
The price is $563
Jun 7 - Jun 8
Total with taxes and fees
St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres

Walk to St. Charles Entertainment

Walk to St. Charles Entertainment
Saint Charles
9.0 out of 10, Wonderful, (10 reviews)
"We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. "
United States
Chloe
$295 nightly
The price is $324
Jun 7 - Jun 8
Total with taxes and fees
Walk to St. Charles Entertainment

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
$250 nightly
The price is $275
Jun 7 - Jun 8
Total with taxes and fees
Duplex Hideaway in St. Charles, MO

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (78 reviews)
"Great communication from host, cute house in an awesome location. Will definitely be staying again!"
United States
Sydney W.
$222 nightly
The price is $238
Jun 8 - Jun 9
Total with taxes and fees
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

The Driftwood Den | Boho-Inspired 2-Bedroom

The Driftwood Den | Boho-Inspired 2-Bedroom
St. Charles Historic District
10.0 out of 10, Exceptional, (2 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
$302 nightly
The price is $332
Jun 7 - Jun 8
Total with taxes and fees
The Driftwood Den | Boho-Inspired 2-Bedroom

Cottage on Historic Main Street- Low Cleaning fee

Cottage on Historic Main Street- Low Cleaning fee
St. Charles Historic District
10.0 out of 10, Exceptional, (18 reviews)
"A very quiet, clean and relaxing stay. "
United States
Dora S.
$274 nightly
The price is $293
Jun 15 - Jun 16
Total with taxes and fees
Cottage on Historic Main Street- Low Cleaning fee

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
9.8 out of 10, Exceptional, (19 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
$262 nightly
The price is $288
Jun 8 - Jun 9
Total with taxes and fees
Charming Duplex on Main

Historic 5th Street House - Fully Rehabbed # 2

Historic 5th Street House - Fully Rehabbed # 2
St. Charles Historic District
8.6 out of 10, Excellent, (14 reviews)
"Wonderful place to stay would definitely recommend "
United States
Steven S.
$225 nightly
The price is $253
Jun 7 - Jun 8
Total with taxes and fees
Historic 5th Street House - Fully Rehabbed # 2

Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (37 reviews)
"Lovely place to stay!"
United States
Margaret A.
$364 nightly
The price is $400
Jun 7 - Jun 8
Total with taxes and fees
Historic Main St. Customs House Upstairs Apartment

St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (154 reviews)
"Clean house, everything worked, great location "
United States
Michael P.
$260 nightly
The price is $278
Jun 7 - Jun 8
Total with taxes and fees
St. Charles 1860's Gem - Sleeps 6!

Dog-Friendly Townhome Near Streets of Saint Charles

Dog-Friendly Townhome Near Streets of Saint Charles
Saint Charles
9.0 out of 10, Wonderful, (9 reviews)
"Very comfortable bed and pillows. Coffee was there when we woke up- everything provided."
United States
Barbara T.
$307 nightly
The price is $338
Jun 7 - Jun 8
Total with taxes and fees
Dog-Friendly Townhome Near Streets of Saint Charles

Main Street Balcony Apartment

Main Street Balcony Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (37 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
$428 nightly
The price is $472
Jun 7 - Jun 8
Total with taxes and fees
Main Street Balcony Apartment

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (171 reviews)
"Host was welcoming, the place was extremely clean, the location was perfect."
United States
Adam P.
$245 nightly
The price is $262
Jun 7 - Jun 8
Total with taxes and fees
The Lofts of North Main Street

Cottage on Main st- Low Cleaning Fee

Cottage on Main st- Low Cleaning Fee
St. Charles Historic District
10.0 out of 10, Exceptional, (8 reviews)
"Good location. Decorated very nicely. "
United States
Debbie A.
$263 nightly
The price is $282
Jun 29 - Jun 30
Total with taxes and fees
Cottage on Main st- Low Cleaning Fee

Stay on Main Historic Studio

Stay on Main Historic Studio
St. Charles Historic District
9.0 out of 10, Wonderful, (34 reviews)
"From the welcome email with clear concise directions on how to enter with door codes to a dwelling that had everything I needed with a very comfortable bed, it was a great stay and I wanted for nothing."
United States
Jacob G.
$208 nightly
The price is $229
Jun 15 - Jun 16
Total with taxes and fees
Stay on Main Historic Studio

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (60 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
$259 nightly
The price is $277
Jun 14 - Jun 15
Total with taxes and fees
Amazing Renovated Historic Loft on Main Street

The Original Custom House!

The Original Custom House!
St. Charles Historic District
9.6 out of 10, Exceptional, (38 reviews)
"The location is excellent. "
United States
McRay H.
$363 nightly
The price is $399
Jun 9 - Jun 10
Total with taxes and fees
The Original Custom House!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $138 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟: This St. Charles vacation home rental offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Some other top choices in St. Charles are The St. Charles Guest House, lovely historic home, fun for families and groups and St. Charles 1860's Gem - Sleeps 6!.

How many vacation rentals are there in St. Charles?

Expedia has 85 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and First Missouri State Capitol Historic Site.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.