Title: Flights to Greenville from Ithaca from $254 (ITH to GSP) - Expedia.com ![Greenville which includes a river or creek, a city and a bridge](https://images.trvl-media.com/place/1388/2f1c4846-4013-4641-a8dd-db2da5ca5774.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina ![](https://images.trvl-media.com/place/1388/2f1c4846-4013-4641-a8dd-db2da5ca5774.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # $254 Cheap Flights from Ithaca (ITH) to Greenville (GSP) [View $254 flight on Wed, Apr 1, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:ITH,to:GSP,departure:4/1/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:253.50&airProductToken=AQqlAQo1CMSYARIENTI2NRjoPCCpUSjblYkDMLOWiQM4RUAAWAFqCU1BSU5CQVNJQ3IITEFWTkEwQlEKNQjEmAESBDIyMjcYqVEg4FwojpeJAzCsmIkDOEVAAVgBaglNQUlOQkFTSUNyCExBVk5BMEJRCjUIxJgBEgQxMjczGOBcIMZ8KJOZiQMwyZmJAzhFQAFYAWoJTUFJTkJBU0lDcghMQVZOQTBCURIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travelers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Ithaca, NY (ITH-Tompkins Regional) to Greenville-Spartanburg Intl. Airport (GSP) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.com/Flights-Search?leg1=from:ITH,to:GSP,departure:3/15/2026TANYT&leg2=from:GSP,to:ITH,departure:3/22/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.com/Flights-Search?leg1=from:ITH,to:GSP,departure:3/15/2026TANYT&leg2=from:GSP,to:ITH,departure:3/22/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) ## Cheap Flights from Ithaca to Greenville (ITH-GSP) Prices were available within the past 7 days and start at $254 for one-way flights and $349 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Sat, Mar 7 - Tue, Mar 10 ITH Ithaca GSP Greenville $349 Roundtrip found 23 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:3/7/2026TANYT&leg2=from:GSP,to:ITH,departure:3/10/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:349.00&airProductToken=AQpmCiAIxJgBEgQ1MjY1GOg8IKlRKPX8hgMw0P2GAzhFQABYAQogCMSYARIEMjIyNxipUSDgXCiq_oYDMND_hgM4RUABWAEKIAjEmAESBDMxNDcY4Fwgxnwo-_-GAzCvgIcDOEVAAVgBCmYKIAjEmAESBDMwMjgYxnwg4FwopJ6HAzDjnocDOEVAAFgBCiAIxJgBEgQyNDIwGOBcIKlRKKKfhwMwqKCHAzhFQAFYAQogCMSYARIENTMxNRipUSDoPCiMoYcDMNWhhwM4RUABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Sat, Mar 7 - Wed, Mar 11 ITH Ithaca GSP Greenville $364 Roundtrip found 23 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:3/7/2026TANYT&leg2=from:GSP,to:ITH,departure:3/11/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:364.00&airProductToken=AQpmCiAIxJgBEgQ1MjY1GOg8IKlRKPX8hgMw0P2GAzhFQABYAQogCMSYARIEMjIyNxipUSDgXCiq_oYDMND_hgM4RUABWAEKIAjEmAESBDMxNDcY4Fwgxnwo-_-GAzCvgIcDOEVAAVgBCmYKIAjEmAESBDMwMjgYxnwg4FwoxKmHAzCDqocDOEVAAFgBCiAIxJgBEgQyNDIwGOBcIKlRKMKqhwMwyKuHAzhFQAFYAQogCMSYARIENTMxNRipUSDoPCisrIcDMPWshwM4RUABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Wed, Mar 4 - Tue, Mar 10 ITH Ithaca GSP Greenville $418 Roundtrip found 23 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:3/4/2026TANYT&leg2=from:GSP,to:ITH,departure:3/10/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:418.00&airProductToken=AQpmCiAIxJgBEgQ1MjY1GOg8IKlRKJXbhgMw8NuGAzhFQABYAQogCMSYARIEMjIyNxipUSDgXCjK3IYDMPDdhgM4RUABWAEKIAjEmAESBDEyNzMY4Fwgxnwo5N6GAzCW34YDOEVAAVgBCmYKIAjEmAESBDMwMjgYxnwg4FwopJ6HAzDjnocDOEVAAFgBCiAIxJgBEgQyNDIwGOBcIKlRKKKfhwMwqKCHAzhFQAFYAQogCMSYARIENTMxNRipUSDoPCiMoYcDMNWhhwM4RUABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Thu, Apr 30 - Mon, May 4 ITH Ithaca GSP Greenville $432 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:4/30/2026TANYT&leg2=from:GSP,to:ITH,departure:5/4/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:431.55&airProductToken=AQpwCjYI1YIBEgQ0OTM5GOg8IIgYKKLciwMw9NyLAzhOQABYAWoKMV9iYXNpY2Vjb3IIU0ZBMkFGQk4KNgjVggESBDQ5NjEYiBggxnwon92LAzCG3osDOE5AAFgBagoxX2Jhc2ljZWNvcghTRkEyQUZCTgpwCjYI1YIBEgQ0MzgzGMZ8IIgYKMePjAMwppCMAzhOQABYAWoKMV9iYXNpY2Vjb3IIU0ZBMkFGQk4KNgjVggESBDQ5NTAYiBgg6Dwo8JCMAzDAkYwDOE5AAFgBagoxX2Jhc2ljZWNvcghTRkEyQUZCThIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAs) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Wed, Mar 4 - Wed, Mar 11 ITH Ithaca GSP Greenville $433 Roundtrip found 23 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:3/4/2026TANYT&leg2=from:GSP,to:ITH,departure:3/11/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:432.99&airProductToken=AQpmCiAIxJgBEgQ1MjY1GOg8IKlRKJXbhgMw8NuGAzhFQABYAQogCMSYARIEMjIyNxipUSDgXCjK3IYDMPDdhgM4RUABWAEKIAjEmAESBDEyNzMY4Fwgxnwo5N6GAzCW34YDOEVAAVgBCmYKIAjEmAESBDMwMjgYxnwg4FwoxKmHAzCDqocDOEVAAFgBCiAIxJgBEgQyNDIwGOBcIKlRKMKqhwMwyKuHAzhFQAFYAQogCMSYARIENTMxNRipUSDoPCisrIcDMPWshwM4RUABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Sat, Mar 7 - Sun, Mar 8 ITH Ithaca GSP Greenville $439 Roundtrip found 23 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:3/7/2026TANYT&leg2=from:GSP,to:ITH,departure:3/8/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:439.00&airProductToken=AQpmCiAIxJgBEgQ1MjY1GOg8IKlRKPX8hgMw0P2GAzhFQABYAQogCMSYARIEMjIyNxipUSDgXCiq_oYDMND_hgM4RUABWAEKIAjEmAESBDMxNDcY4Fwgxnwo-_-GAzCvgIcDOEVAAVgBCmYKIAjEmAESBDMwMjgYxnwg4Fwo5IeHAzCjiIcDOEVAAFgBCiAIxJgBEgQyNDIwGOBcIKlRKOKIhwMw6ImHAzhFQAFYAQogCMSYARIENTMxNRipUSDoPCjMiocDMJWLhwM4RUABWAESCggBEAEYASoCREwYASIECAEQASgEMAE) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Mar 2 - Sat, Mar 7 ITH Ithaca GSP Greenville $454 Roundtrip found 23 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:3/2/2026TANYT&leg2=from:GSP,to:ITH,departure:3/7/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:454.00&airProductToken=AQpmCiAIxJgBEgQ1MjY1GOg8IKlRKNXEhgMwsMWGAzhFQABYAQogCMSYARIEMjIyNxipUSDgXCiKxoYDMLDHhgM4RUABWAEKIAjEmAESBDEyNzMY4FwgxnwopMiGAzDWyIYDOEVAAVgBCmcKIAjEmAESAzY4NhjGfCDjtAEo5P2GAzDS_oYDOEVAAFgBCiEIxJgBEgQ1Mjg4GOO0ASCpUSiE_4YDMP3_hgM4RUABWAEKIAjEmAESBDUzMTUYqVEg6Dwow4CHAzCLgYcDOEVAAVgBEgoIARABGAEqAkRMGAEiBAgBEAEoBDAB) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Wed, Apr 1 - Thu, Apr 2 ITH Ithaca GSP Greenville $497 Roundtrip found 10 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:4/1/2026TANYT&leg2=from:GSP,to:ITH,departure:4/2/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:496.40&airProductToken=AQpwCjYI1YIBEgQ0OTM5GOg8IIgYKPiViQMwypaJAzhOQABYAWoKMV9iYXNpY2Vjb3IIV0FBMkFEQk4KNgjVggESBDQ0MTMYiBggxnwo_5aJAzDjl4kDOE5AAFgBagoxX2Jhc2ljZWNvcghXQUEyQURCTgpwCjYI1YIBEgQ0MzEzGMZ8IIgYKM6niQMwsKiJAzhOQABYAWoKMV9iYXNpY2Vjb3IIV0FBMkFEQk4KNgjVggESBDQ5NTAYiBgg6Dwo_6iJAzDPqYkDOE5AAFgBagoxX2Jhc2ljZWNvcghXQUEyQURCThIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAs) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Thu, Apr 30 - Tue, May 5 ITH Ithaca GSP Greenville $499 Roundtrip found 3 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:4/30/2026TANYT&leg2=from:GSP,to:ITH,departure:5/5/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:499.00&airProductToken=AQqlAQo1CMSYARIENTI2NRjoPCCpUSjw24sDMMLciwM4RUAAWAFqCU1BSU5CQVNJQ3IIS0ZVR0EwQlEKNQjEmAESBDIyMjcYqVEg4FwokN2LAzCz3osDOEVAAVgBaglNQUlOQkFTSUNyCEtGVUdBMEJRCjUIxJgBEgQxOTc0GOBcIMZ8KN7eiwMwld-LAzhFQAFYAWoJTUFJTkJBU0lDcghLRlVHQTBCUQqlAQo1CMSYARIEMzAyOBjGfCDgXCimlIwDMOSUjAM4RUAAWAFqCU1BSU5CQVNJQ3IIVEZWT0EwQlEKNQjEmAESBDI0MjAY4FwgqVEor5WMAzC3lowDOEVAAVgBaglNQUlOQkFTSUNyCFRGVk9BMEJRCjUIxJgBEgQ1MzE1GKlRIOg8KICXjAMw1ZeMAzhFQAFYAWoJTUFJTkJBU0lDcghURlZPQTBCURIMCAEQARgBKgJETDIAGAEiBAgBEAEoAigDKAQwAQ) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Thu, Apr 30 - Mon, May 4 ITH Ithaca GSP Greenville $502 Roundtrip found 5 days ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:ITH,to:GSP,departure:4/30/2026TANYT&leg2=from:GSP,to:ITH,departure:5/4/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:501.55&airProductToken=AQpmCjEI1YIBEgQ0OTM5GOg8IIgYKKLciwMw9NyLAzhTQABYAWoFMl9lY29yCFNGQTJBRkROCjEI1YIBEgQ0OTYxGIgYIMZ8KJ_diwMwht6LAzhTQABYAWoFMl9lY29yCFNGQTJBRkROCmYKMQjVggESBDQzODMYxnwgiBgox4-MAzCmkIwDOFNAAFgBagUyX2Vjb3IIU0ZBMkFGRE4KMQjVggESBDQ5NTAYiBgg6Dwo8JCMAzDAkYwDOFNAAFgBagUyX2Vjb3IIU0ZBMkFGRE4SCggBEAEYASoCVUEYASIECAEQASgCKAMoBDAL) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=FTG_SPRING_PROMO_) ## Frequently asked questions ### How much does a flight from Tompkins Regional Airport (ITH) to Greenville-Spartanburg Intl. Airport (GSP) cost? ### What is the cheapest month to fly from Tompkins Regional Airport (ITH) to Greenville-Spartanburg Intl. Airport (GSP)? ### What is the cheapest airline that flies from Tompkins Regional Airport (ITH) to Greenville-Spartanburg Intl. Airport (GSP)? ### How many flights per day from Tompkins Regional Airport (ITH) to Greenville-Spartanburg Intl. Airport (GSP)? ### What day of the week has the most flights from ITH to GSP? ### What is the best time to fly from Tompkins Regional Airport (ITH) to Greenville-Spartanburg Intl. Airport (GSP)? ### Is it cheaper to buy a plane ticket from Tompkins Regional Airport (ITH) to Greenville-Spartanburg Intl. Airport (GSP) last-minute? ### Is it cheaper to book an ITH to GSP flight and hotel package? ### Can I cancel or change the date of my flight from Tompkins Regional Airport (ITH) to Greenville-Spartanburg Intl. Airport (GSP)? ## Travel information | Origin airport | Tompkins Regional | | ------------------- | ---------------------------- | | Destination airport | Greenville-Spartanburg Intl. | | Airlines serving | Delta, United | | Roundtrip price | $349 | | Distance | 609 mi | ## Book with confidence # Ithaca to Greenville Flights The cheapest times to fly from Ithaca to Greenville On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Ithaca to Greenville are during the month of March. You can find some of the cheapest flights from Ithaca to Greenville with Expedia's search tool and vast selection of airlines. The best time to book a flight from Ithaca to Greenville Sunday is one of the best days to book for cheap flights from Ithaca to Greenville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. How to find cheap round-trip tickets from Ithaca to Greenville Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Ithaca to Greenville in 2026\. You can also book with separate airlines for your outbound and return journeys, from $254 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Ithaca to Greenville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Ithaca to Greenville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. \*Terms apply. Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. 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