Find 2 Star Hotels in Defiance, MO from $70

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Check availability on Defiance 2 Star Hotels

Compare Defiance 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Relax Inn Saint Charles

2.0 star property
6.6 out of 10, (1006)
"Good stay"
$61 nightly
The price is $71
Oct 12 - Oct 13
Total with taxes and fees
Relax Inn Saint Charles

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
8.8 out of 10, Excellent, (1008)
"Great hotel! "
$87 nightly
The price is $103
Oct 14 - Oct 15
Total with taxes and fees
Sleep Inn & Suites O'Fallon MO - Technology Drive

Best Western Plus St. Louis West-Westport

2.5 star property
8.0 out of 10, Very Good, (1005)
"It was a very nice place"
$88 nightly
The price is $102
Oct 19 - Oct 20
Total with taxes and fees
Best Western Plus St. Louis West-Westport

Hampton Inn St. Charles St. Peters

2.5 star property
8.0 out of 10, Very Good, (1007)
"Excellent hotel. Excellent location, friendly staff, and delicious breakfast."
$98 nightly
The price is $112
Oct 19 - Oct 20
Total with taxes and fees
Hampton Inn St. Charles St. Peters

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 star property
9.4 out of 10, Exceptional, (1012)
"Quality place to stay"
$114 nightly
The price is $131
Oct 21 - Oct 22
Total with taxes and fees
Country Inn & Suites by Radisson, St. Charles Historic District

Baymont by Wyndham St. Charles

2.5 star property
8.0 out of 10, Very Good, (1000)
"Friendly staff, great breakfast and clean"
Baymont by Wyndham St. Charles

Hampton Inn & Suites St. Charles Old Town Area

2.5 star property
9.2 out of 10, Wonderful, (595)
"Good location, friendly, helpful staff."
$111 nightly
The price is $139
Oct 26 - Oct 27
Total with taxes and fees
Hampton Inn & Suites St. Charles Old Town Area

Comfort Suites St Charles - St Louis

2.5 star property
8.4 out of 10, Very Good, (1010)
"Friendly staff and hotel is very clean! Furniture in room is dated but beds are very comfortable "
$96 nightly
The price is $110
Oct 19 - Oct 20
Total with taxes and fees
Comfort Suites St Charles - St Louis

Country Inn & Suites by Radisson, St. Peters, MO

2.5 star property
8.2 out of 10, Very Good, (1008)
"This was an amazing stay"
$102 nightly
The price is $117
Oct 26 - Oct 27
Total with taxes and fees
Country Inn & Suites by Radisson, St. Peters, MO

Holiday Inn Express St. Louis West - O'Fallon by IHG

2.5 star property
8.6 out of 10, Excellent, (795)
"The staff were very nice & the breakfast was enjoyable. The hotel was clean."
$95 nightly
The price is $112
Oct 19 - Oct 20
Total with taxes and fees
Holiday Inn Express St. Louis West - O'Fallon by IHG

Comfort Inn & Suites Chesterfield - St. Louis

2.5 star property
8.0 out of 10, Very Good, (1006)
"Great place to stay"
$93 nightly
The price is $107
Oct 27 - Oct 28
Total with taxes and fees
Comfort Inn & Suites Chesterfield - St. Louis

Extended Stay America Suites St Louis St Peters

2.5 star property
7.0 out of 10, Good, (585)
"Location was perfect"
$85 nightly
The price is $98
Nov 2 - Nov 3
Total with taxes and fees
Extended Stay America Suites St Louis St Peters

Comfort Inn & Suites St. Louis - O'Fallon

2.5 star property
7.6 out of 10, Good, (1005)
"And nice hotel at a nice price "
$77 nightly
The price is $90
Oct 26 - Oct 27
Total with taxes and fees
Comfort Inn & Suites St. Louis - O'Fallon

Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

2.5 star property
5.8 out of 10, (1000)
"The staff was wonderful and polite and helpful they need a raise!!!"
$77 nightly
The price is $89
Oct 31 - Nov 1
Total with taxes and fees
Extended Stay America Select Suites - St. Louis - Westport - E Lackland Rd

Sonesta Simply Suites St Louis Earth City

2.0 star property
8.6 out of 10, Excellent, (780)
"Always a great stay"
$79 nightly
The price is $91
Nov 2 - Nov 3
Total with taxes and fees
Sonesta Simply Suites St Louis Earth City

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

2.5 star property
9.0 out of 10, Wonderful, (974)
"Comfortable beds, good breakfast, and great hotel!"
$91 nightly
The price is $106
Oct 31 - Nov 1
Total with taxes and fees
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Super 8 by Wyndham Eureka/Six Flags Nearby

2.0 star property
7.0 out of 10, Good, (1005)
"Clean room."
$60 nightly
The price is $70
Oct 26 - Oct 27
Total with taxes and fees
Super 8 by Wyndham Eureka/Six Flags Nearby

Fairfield Inn & Suites Wentzville

2.5 star property
9.0 out of 10, Wonderful, (615)
"Wonderful place to stay."
$137 nightly
The price is $157
Oct 19 - Oct 20
Total with taxes and fees
Fairfield Inn & Suites Wentzville

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

2.5 star property
4.6 out of 10, (1005)
"The"
$68 nightly
The price is $79
Oct 19 - Oct 20
Total with taxes and fees
Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Days Inn by Wyndham St Peters/St Charles

2.0 star property
6.4 out of 10, (994)
"The carpet felt a little damp but aside from that the room was clean and comfortable. "
$67 nightly
The price is $77
Oct 13 - Oct 14
Total with taxes and fees
Days Inn by Wyndham St Peters/St Charles
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Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

Top Defiance Hotel Reviews

Find out more about Defiance

Defiance Motel Guide

Planning a getaway with only a few bucks to spare? Expedia can help! With the inexpensive rates at the top motels in Defiance, St. Louis you can put together the vacation of your dreams without spending every penny of your yearly travel budget.

These smaller places are ideal if you need a home base that lets you easily explore the local sights; many of the best motels in Defiance are located near major freeways and public transportation. Plus, when you book a cheap deal on a motel in Defiance, you’ll find quiet rooms, complimentary toiletries, and comfortable sleeping areas, so you can unwind after a long day.

No matter which motel you choose, don't forget to use the travel tools at Expedia to search for local discounts, compare rates on the hottest motels, and plan your next vacation. You won't believe how budget-friendly an amazing getaway can be.

Also, feel free to check out the motels near me page to find the cheapest deals on motels near your current location.

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