Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search over 1,000,000 properties worldwide and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Brookline

Tonight Jun 26 - Jun 27
This weekend Jun 28 - Jun 30
Next weekend Jul 5 - Jul 7

Featured Brookline 5 Star Hotels

See all 1,270 Properties in Brookline

Estimated price for 1 night/2 adults

InterContinental Boston
InterContinental Boston
5.0 out of 5.0 510 Atlantic Ave, Boston, MA
Free Cancellation
4.6/5 (1667 reviews)
$195/ night for 2 guests

The staff hospitality was amazing, felt like home. I have stayed here many times over the past 3 years. I will surely come back again

Reviewed on Jun 21, 2019
The Liberty, a Marriott Luxury Collection Hotel, Boston
The Liberty, a Marriott Luxury Collection Hotel, Boston
5.0 out of 5.0 215 Charles St, Boston, MA
Free Cancellation
4.5/5 (2035 reviews)
$194/ night for 2 guests

Good locations and that hotel was a wonderful building!

Reviewed on May 30, 2019
Boston Harbor Hotel
Boston Harbor Hotel
5.0 out of 5.0 70 Rowes Wharf, Boston, MA
Free Cancellation
4.8/5 (1362 reviews)
$426/ night for 2 guests

Harbor view made for an unforgettable room. Would have liked a BBC news or similar TV channel.

Reviewed on Jun 11, 2019
Four Seasons Hotel Boston
Four Seasons Hotel Boston
5.0 out of 5.0 200 Boylston St, Boston, MA
4.6/5 (262 reviews)
$574/ night for 2 guests

They have a beautiful indoor pool deck and gym on the 8th floor. The room service was excellent. The housekeeping service was excellent . My only complaint is that the Sunday brunch was way overpriced.

Reviewed on Apr 21, 2019
Fifteen Beacon
Fifteen Beacon
5.0 out of 5.0 15 Beacon St, Boston, MA
Free Cancellation
4.6/5 (232 reviews)
$445/ night for 2 guests

The boutique size and personal services made it feel very comfortable

Reviewed on May 28, 2019
Mandarin Oriental Boston
Mandarin Oriental Boston
5.0 out of 5.0 776 Boylston St, Boston, MA
Free Cancellation
4.6/5 (168 reviews)
$545/ night for 2 guests

Kind and professional staff from greeting to departure. Rooms were spacious and comfortable and accommodations plentiful as expected. Awesome location - Boylston street blocks from the Commons. Wonderful Mall attached and parking easy to access. Just a wonderful stay.

Reviewed on Apr 25, 2019
The Ritz-Carlton, Boston
The Ritz-Carlton, Boston
5.0 out of 5.0 10 Avery St, Boston, MA
Free Cancellation
4.4/5 (198 reviews)
$595/ night for 2 guests

Great location Walkable Near of great restaurants Good for family (kids love it) At 3 minutes from the gardens Room too small.

Reviewed on Jun 24, 2019
Four Seasons Hotel One Dalton Street, Boston
Four Seasons Hotel One Dalton Street, Boston
5.0 out of 5.0 One Dalton Street, Boston, MA
Free Cancellation
$620/ night for 2 guests
Map

You enjoy the finer things in life, both at home and on vacation. Indulge yourself on your upcoming sabbatical. There's no reason to delay a getaway to Brookline any longer. You'll join the multitudes of vacationers who have made Brookline so fashionable recently. The accommodations in Brookline also offer great customer service, averaging 3.8 in our ranking system, so you know you'll be taken care of. What are you waiting for? Our 5-star hotels in Brookline are the perfect places to relax in when you really need to escape.

Get a Great Deal on 5-Star Hotels in Brookline

You can expect superior customer service from your hotel. Excellent service, delicious meals, and one-on-one attention are all ready for you. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Brookline offer great customer service, averaging 3.8 in our ranking system, setting you up for a truly relaxing getaway. What creature comforts do you want in your lodging? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore the review section and see what previous visitors have said. You're sure to find exactly what you're looking for!

You won't sleep and order room service the entire time, though. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Brookline are the perfect place to relax after a busy day.

Make Your Escape

The results are in, and Brookline 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. It's time to plan your next great escape -- Expedia can help you land a great deal on accommodation. Select one of Expedia's Brookline 5-star hotels today and settle down in complete comfort tomorrow.

Recently booked 5 Star Hotels in Brookline

Courtyard by Marriott Boston Brookline
3.0 out of 5.0
Last booking: 11 hours ago
Beacon Inn 1750
3.0 out of 5.0
Last booking: 12 hours ago
Beacon Inn 1087
2.5 out of 5.0
Last booking: 16 hours ago
Homewood Suites by Hilton Boston Brookline-Longwood Medical
3.0 out of 5.0
Last booking: 20 hours ago