Find hotels in Colleton River, Bluffton

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Our top choices for Colleton River hotels

Premium bedding, individually decorated, individually furnished
Beaufort Inn

Beaufort Inn

Beaufort Inn
3.5 star property
11.3 mi from Colleton River
9.0 out of 10, Wonderful, (1002)
"If you are looking for a unique place to stay, this would be it. Staff was great and the rooms were clean."
United States
Samantha
$148 nightly
The price is $163
Jan 19 - Jan 20, 2026
Total with taxes and fees
Beaufort Inn
Studio Suite, 1 King Bed with Sofa bed | In-room safe, iron/ironing board, WiFi, bed sheets
Palmera Inn and Suites

Palmera Inn and Suites

Palmera Inn and Suites
3.0 star property
9.9 mi from Colleton River
9.0 out of 10, Wonderful, (1165)
"Great stay, staff and amenities!"
United States
garret
$99 nightly
The price is $109
Jan 4 - Jan 5, 2026
Total with taxes and fees
Palmera Inn and Suites
Outdoor pool, open 8:00 AM to midnight, pool umbrellas, sun loungers
Beach House Resort Hilton Head

Beach House Resort Hilton Head

Beach House Resort Hilton Head
4.0 star property
11.3 mi from Colleton River
8.8 out of 10, Excellent, (1008)
"Warm and welcoming staff Great location Clean rooms and bathrooms Comfortable bed, had a good nights rest Just oerfect"
United States
RAMAN
$146 nightly
The price is $160
Jan 4 - Jan 5, 2026
Total with taxes and fees
Beach House Resort Hilton Head
Exterior
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island
4.0 star property
10.7 mi from Colleton River
8.6 out of 10, Excellent, (1182)
"Beautiful area and the hotel staff were so friendly. Would love to stay for several days! "
United States
Hannah
$177 nightly
The price is $195
Jan 3 - Jan 4, 2026
Total with taxes and fees
Sonesta Resort Hilton Head Island
2 bars/lounges, poolside bar
The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa

The Westin Hilton Head Island Resort & Spa
4.0 star property
8.9 mi from Colleton River
8.4 out of 10, Very Good, (1002)
"Beautiful room. Ocean view. The hotel was magical "
United States
Shirene
$168 nightly
The price is $185
Jan 18 - Jan 19, 2026
Total with taxes and fees
The Westin Hilton Head Island Resort & Spa
Exterior
Holiday Inn Express Hilton Head Island by IHG

Holiday Inn Express Hilton Head Island by IHG

Holiday Inn Express Hilton Head Island by IHG
2.5 star property
11.1 mi from Colleton River
8.4 out of 10, Very Good, (342)
"The clean room and location was great. "
United States
ROBERT
$89 nightly
The price is $98
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Hilton Head Island by IHG
Basic Room, Multiple Beds, Non Smoking | Free WiFi, bed sheets
Simple Rewards Inn

Simple Rewards Inn

Simple Rewards Inn
2.5 star property
7 mi from Colleton River
8.8 out of 10, Excellent, (1001)
"Spotless rooms, friendly staff and always fresh coffee!!!"
United States
Gary
$69 nightly
The price is $76
Jan 14 - Jan 15, 2026
Total with taxes and fees
Simple Rewards Inn
Exterior
Best Western Sea Island Inn

Best Western Sea Island Inn

Best Western Sea Island Inn
2.5 star property
11.2 mi from Colleton River
9.4 out of 10, Exceptional, (1002)
"Perfect spot!"
United States
Tricia
$140 nightly
The price is $154
Dec 22 - Dec 23
Total with taxes and fees
Best Western Sea Island Inn
3 outdoor pools, open 8:00 AM to 10:00 PM, cabanas (surcharge)
Omni Hilton Head Oceanfront Resort

Omni Hilton Head Oceanfront Resort

Omni Hilton Head Oceanfront Resort
4.0 star property
10.4 mi from Colleton River
9.0 out of 10, Wonderful, (1002)
"The room was clean, spacious and all staff were amazing! When we return to HH we will definitely stay at the Omni!"
United States
Timothy
$190 nightly
The price is $205
Jan 13 - Jan 14, 2026
Total with taxes and fees
Omni Hilton Head Oceanfront Resort
Meeting facility
Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island

Hilton Beachfront Resort & Spa Hilton Head Island
4.5 star property
10.2 mi from Colleton River
8.4 out of 10, Very Good, (1396)
"Great location "
United States
Ngone Lon
$173 nightly
The price is $191
Dec 28 - Dec 29
Total with taxes and fees
Hilton Beachfront Resort & Spa Hilton Head Island
Snack bar
Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC
2.5 star property
10.4 mi from Colleton River
9.0 out of 10, Wonderful, (711)
"Awesome stay!!!"
United States
Michael
$93 nightly
The price is $103
Dec 28 - Dec 29
Total with taxes and fees
Tru by Hilton Beaufort, SC
Outdoor pool, pool umbrellas, sun loungers
Hilton Grand Vacations Club Ocean Oak Resort Hilton Head

Hilton Grand Vacations Club Ocean Oak Resort Hilton Head

Hilton Grand Vacations Club Ocean Oak Resort Hilton Head
4.0 star property
11.4 mi from Colleton River
9.6 out of 10, Exceptional, (333)
"Beautiful accommodations, excellent staff, very clean"
United States
Carol
$167 nightly
The price is $184
Jan 3 - Jan 4, 2026
Total with taxes and fees
Hilton Grand Vacations Club Ocean Oak Resort Hilton Head
Exterior
Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort
3.0 star property
11.3 mi from Colleton River
8.4 out of 10, Very Good, (1002)
"Good hotel"
United States
joshua
$84 nightly
The price is $93
Jan 3 - Jan 4, 2026
Total with taxes and fees
Hilton Garden Inn Beaufort
Exterior
607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort
2.5 star property
11.3 mi from Colleton River
9.8 out of 10, Exceptional, (89)
"Great Inn! Location, view, cleanliness, friendly staff!"
United States
Nicole
$142 nightly
The price is $156
Dec 23 - Dec 24
Total with taxes and fees
607 Bay Inn Downtown Beaufort
Lobby
Hampton Inn Hilton Head

Hampton Inn Hilton Head

Hampton Inn Hilton Head
2.5 star property
7.9 mi from Colleton River
8.4 out of 10, Very Good, (1006)
"Nice staff, clean room, tasty food "
United States
William
$93 nightly
The price is $103
Dec 28 - Dec 29
Total with taxes and fees
Hampton Inn Hilton Head
Exterior
Holiday Inn Express Bluffton at Hilton Head Area by IHG

Holiday Inn Express Bluffton at Hilton Head Area by IHG

Holiday Inn Express Bluffton at Hilton Head Area by IHG
2.5 star property
4.9 mi from Colleton River
9.0 out of 10, Wonderful, (1001)
"Was a great place to stay, its behind an alley for target, but was safe with no issues. "
United States
Michael
$103 nightly
The price is $113
Dec 28 - Dec 29
Total with taxes and fees
Holiday Inn Express Bluffton at Hilton Head Area by IHG
Exterior
Rhett House Inn

Rhett House Inn

Rhett House Inn
4.0 star property
11.3 mi from Colleton River
9.2 out of 10, Wonderful, (643)
"What a lovely stay. Beautiful, clean and friendly staff made this stay wonderful. Will stay again while in Beaufort."
United States
REBECCA
$160 nightly
The price is $176
Jan 7 - Jan 8, 2026
Total with taxes and fees
Rhett House Inn
Lobby
Spark by Hilton Bluffton Hilton Head Island

Spark by Hilton Bluffton Hilton Head Island

Spark by Hilton Bluffton Hilton Head Island
2.5 star property
Plantation Point, 4.8 mi from Colleton River
8.4 out of 10, Very Good, (152)
"Nice hotel "
United States
Robert
$85 nightly
The price is $94
Jan 19 - Jan 20, 2026
Total with taxes and fees
Spark by Hilton Bluffton Hilton Head Island
Balcony
Anchorage 1770

Anchorage 1770

Anchorage 1770
5.0 star property
11.2 mi from Colleton River
9.2 out of 10, Wonderful, (218)
"Great property at a wonderful location."
United States
Dave
$260 nightly
The price is $286
Dec 22 - Dec 23
Total with taxes and fees
Anchorage 1770
Rooftop terrace
Courtyard by Marriott Hilton Head Island

Courtyard by Marriott Hilton Head Island

Courtyard by Marriott Hilton Head Island
3.0 star property
11 mi from Colleton River
9.0 out of 10, Wonderful, (741)
"Hotel was in great shape and well kept. "
United States
Timothy
$110 nightly
The price is $121
Jan 14 - Jan 15, 2026
Total with taxes and fees
Courtyard by Marriott Hilton Head Island
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Colleton River

Find the best Colleton River areas and neighborhoods for the activities you enjoy most.

Palmetto Bluff

Visitors to Palmetto Bluff like its spas and golf courses, and May River Golf Club at Palmetto Bluff is a sight worth a stop.

Old Town Bluffton

You'll enjoy the churches and riverfront in Old Town Bluffton. You might want to make time for a stop at Bluffton Oyster Factory Park or Farmers Market of Bluffton.

Sun City Hilton Head

If you're spending some time in Sun City Hilton Head, Okatie Creek Golf Club and Argent Lakes Golf Course are top sights worth seeing.

Belfair

When in Belfair, you can plan a visit to Rose Hill Mansion and Rose Hill Golf Club, some noteworthy sights in the nearby area.

Brighton Beach

When in Brighton Beach, you can plan a visit to Hilton Head National Golf Club and Tanger Outlets Hilton Head, some noteworthy sights in the nearby area.

Top Colleton River Hotel Reviews

Holiday Inn Express Bluffton at Hilton Head Area by IHG

Holiday Inn Express Bluffton at Hilton Head Area by IHG

10/10 Excellent
"Staff was very courteous."
Danette 1-night trip
Posted 2 days ago
Holiday Inn Express Bluffton at Hilton Head Area by IHG

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Colleton River hotel for you.
How can I save on a Colleton River hotel booking with Expedia?
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How much is the nightly rate at a Colleton River hotel?
Hotel prices in Colleton River often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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