Title: The Best Hotels Closest to Museum of Life and Science in Raleigh for 2026 | Expedia.com [Raleigh Travel Guide](https://expedia.com/Raleigh.dx178300)[Vacation Rentals in Raleigh](https://expedia.com/Raleigh-Vacation-Rentals.d178300.Travel-Guide-VacationRentals)[Flights to Raleigh](https://expedia.com/Cheap-Flights-To-Raleigh.d178300.Travel-Guide-Flights)[Things to do in Raleigh](https://expedia.com/Things-To-Do-In-Raleigh.d178300.Travel-Guide-Activities)[Car Rentals in Museum of Life and Science](https://expedia.com/Car-Rentals-In-Museum-Of-Life-And-Science.d6066241.Car-Rental-Guide)[Museum of Life and Science Vacations](https://expedia.com/Museum-Of-Life-And-Science-Raleigh.d6066241.Vacation-Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 2 - Mar 3](https://www.expedia.com/Hotel-Search?regionId=6066241&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 3 - Mar 4](https://www.expedia.com/Hotel-Search?regionId=6066241&startDate=2026-03-03&endDate=2026-03-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6066241&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6066241&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Museum of Life and Science hotels ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/5d825f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/cf486635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/d095ca5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/b635c3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Durham/North I-85 [](https://www.expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) 0.8 mi from Museum of Life and Science 9.0/10 Wonderful (1,004 reviews) "Very clean hotel. Staff was very pleasant and helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda $118 nightly $134 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/b3df2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/28a254ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/366a4dd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/1de17076.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Durham by IHG [](https://www.expedia.com/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) 1.3 mi from Museum of Life and Science 8.8/10 Excellent (973 reviews) "Room was clean, staff was courteous" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $118 nightly $134 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/cec44ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/fd344660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/ae65d3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Durham near Duke University [](https://www.expedia.com/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) Croasdaile Farm Master, 2 mi from Museum of Life and Science 8.6/10 Excellent (1,005 reviews) "Clean room, hot breakfast buffet" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa $106 nightly $121 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/4b0fbe40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/eefd1cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed (Smoke Free) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/84d2f31a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds (Smoke Free) | Down comforters, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/effe5fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Durham - Duke Univ Medical Center [](https://www.expedia.com/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) 1.3 mi from Museum of Life and Science 6.8/10 (1,000 reviews) "The room vas very clean. It’s an old hotel but it was very clean and had everything I needed!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert $63 nightly $72 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) ![Apartment | 3 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/86ba7427.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/6184c1e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/6727247a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387562/4c923195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walk to Duke Campus 3 Bedroom in Trinity Park [](https://www.expedia.com/Raleigh-Hotels-Walk-To-Duke-Campus-3-Bedroom-In-Trinity-Park.h113387562.Hotel-Information) Trinity Park, 1.8 mi from Museum of Life and Science $182 nightly $206 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Walk-To-Duke-Campus-3-Bedroom-In-Trinity-Park.h113387562.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/126000000/125130000/125123400/125123322/df071013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125130000/125123400/125123322/6d02d454.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125130000/125123400/125123322/ee8b91aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125130000/125123400/125123322/1835d49f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bull City Bungalow - Walk to 9th Street Near Duke [](https://www.expedia.com/Raleigh-Hotels-Bull-City-Bungalow-Walk-To-9th-Street-Near-Duke.h125123322.Hotel-Information) 0.6 mi from Museum of Life and Science $409 nightly $464 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Bull-City-Bungalow-Walk-To-9th-Street-Near-Duke.h125123322.Hotel-Information) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/w3000h2216x0y0-dab9596b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/w3000h2184x0y0-6e51935c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/931a6ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/114000000/113390000/113387600/113387569/19fc7ffa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renovated 2 Bed Walltown Home Walk to Duke A [](https://www.expedia.com/Raleigh-Hotels-Renovated-2-Bed-Walltown-Home-Walk-To-Duke-A.h113387569.Hotel-Information) 1.4 mi from Museum of Life and Science $171 nightly $194 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Renovated-2-Bed-Walltown-Home-Walk-To-Duke-A.h113387569.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/ce4c0314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/f35f9a61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/9aedcffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/ac022859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish Durham Retreat - Walkable, Sleeps 6 [](https://www.expedia.com/Raleigh-Hotels-Stylish-Durham-Retreat-Walkable.h126576024.Hotel-Information) 1.7 mi from Museum of Life and Science $544 nightly $617 total Mar 10 - Mar 11 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Stylish-Durham-Retreat-Walkable.h126576024.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/9047a750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/8a466914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/3b234d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/84262960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Durham/University Medical Center [](https://www.expedia.com/Raleigh-Hotels-Hilton-Garden-Inn-DurhamUniversity-Medical-Center.h6232983.Hotel-Information) 9th Street District, 2.1 mi from Museum of Life and Science 9.2/10 Wonderful (1,000 reviews) "Clean room, staff was all great Amy, Darryl, James everybody . Amenities were great, always a wonderful stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael Keith $139 nightly $157 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Hilton-Garden-Inn-DurhamUniversity-Medical-Center.h6232983.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/0f42bc80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/b6927f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/f15dddb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/c90f9818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Durham McPherson/Duke University Medical Cntr [](https://www.expedia.com/Raleigh-Hotels-Residence-Inn-Durham-McPhersonDuke-University-Medical-Cntr.h10344567.Hotel-Information) Trinity Park, 2 mi from Museum of Life and Science 9.2/10 Wonderful (466 reviews) "Courteous staff, spotless rooms, comfortable bed and pillows." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna F $158 nightly $179 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Residence-Inn-Durham-McPhersonDuke-University-Medical-Cntr.h10344567.Hotel-Information) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/88bdf392.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/29cfc65c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/45c09dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Durham Near Duke University/Downtown [](https://www.expedia.com/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) Croasdaile Farm Master, 2.1 mi from Museum of Life and Science 8.2/10 Very Good (1,005 reviews) "Great friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Terri $114 nightly $129 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/49daf4fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/3439b81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/5b5ea009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/f7b4838d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Durham Hotel [](https://www.expedia.com/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information) Downtown Durham, 2.2 mi from Museum of Life and Science 9.0/10 Wonderful (659 reviews) "Great stay. Very nice boutique hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) nadav $186 nightly $211 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/87483d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/64c7e604.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/1edaea73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/23800/23726/7fa8560d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Durham Marriott City Center [](https://www.expedia.com/Raleigh-Hotels-Durham-Marriott-City-Center.h23726.Hotel-Information) Downtown Durham, 2.2 mi from Museum of Life and Science 8.8/10 Excellent (834 reviews) "Great clean hotel in downtown durham" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott $161 nightly $183 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Durham-Marriott-City-Center.h23726.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/80e8b722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/fa7de522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/81950088.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/39dc9c71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Inn Durham next to Duke University Medical Center [](https://www.expedia.com/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) 2.5 mi from Museum of Life and Science 9.0/10 Wonderful (1,007 reviews) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chase $124 nightly $141 total Mar 6 - Mar 7 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) ![Balcony view](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/66c3cbee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/d6ccf805.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/387037cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/ebe35e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Unscripted Durham, Part of JDV by Hyatt [](https://www.expedia.com/Raleigh-Hotels-Unscripted-Durham.h18023733.Hotel-Information) Downtown Durham, 2.3 mi from Museum of Life and Science 8.2/10 Very Good (1,005 reviews) "We stay here at least annually and always will. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paul $133 nightly $151 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Unscripted-Durham.h18023733.Hotel-Information) ![Ballroom](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/52832fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/108f8814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/46003326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/269273b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Durham [](https://www.expedia.com/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) Downtown Durham, 2.3 mi from Museum of Life and Science 8.4/10 Very Good (1,004 reviews) "Amazing staff, comfortable rooms, best shower, convenient location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lauren $165 nightly $187 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/3a03b169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room dining](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/73e55abf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, City View | Hypo-allergenic bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/9f21eef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/505e32af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Durham Downtown [](https://www.expedia.com/Raleigh-Hotels-Aloft-Durham-Downtown.h10088739.Hotel-Information) American Tobacco District, 2.5 mi from Museum of Life and Science 9.0/10 Wonderful (738 reviews) "perfect stay for a show at DPAC" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $178 nightly $202 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Aloft-Durham-Downtown.h10088739.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/3ad3b6bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/2ecbbac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/7f82e6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/40f303ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Duke Medical Center [](https://www.expedia.com/Raleigh-Hotels-The-Lodge-At-Duke-Medical-Center.h12880.Hotel-Information) 2.5 mi from Museum of Life and Science 8.6/10 Excellent (1,001 reviews) "Room was nice and clean. The location is very convenient. I would definitely stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcela $144 nightly $163 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-The-Lodge-At-Duke-Medical-Center.h12880.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/984d892a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 9:00 AM to 10:00 PM, sun loungers](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/5058af4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/37e60b13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/a7c0ffee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Durham University Medical Center [](https://www.expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information) 3 mi from Museum of Life and Science 9.6/10 Exceptional (424 reviews) "Clean room and very good breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger $121 nightly $137 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/42139333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/8a018572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/1e73f22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/0104cf5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Durham City View [](https://www.expedia.com/Raleigh-Hotels-SpringHill-Suites-By-Marriott-Durham-City-View.h66571463.Hotel-Information) 2.8 mi from Museum of Life and Science 9.2/10 Wonderful (484 reviews) "Staff was wonderful. We love staying here. We will be back on Feb 4th. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robin $137 nightly $155 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Raleigh-Hotels-SpringHill-Suites-By-Marriott-Durham-City-View.h66571463.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17®ionId=6066241&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Museum of Life and Science Hotel Reviews ![Hilton Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/09c549f7_y.jpg) ### Hilton Durham near Duke University 10/10 Excellent "Room was clean and comfortable. Staff were friendly and provided excellent customer service. The restaurant’s dinner was great! Check and check out was easy. The TV did Stop working the last night. stop " [](https://expedia.com/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information) ![The Durham Hotel](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/b7c32975_y.jpg) ### The Durham Hotel 10/10 Excellent "Great space. I will be back." [](https://expedia.com/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information) ![Courtyard Durham Near Duke University/Downtown](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009_y.jpg) ### Courtyard Durham Near Duke University/Downtown 10/10 Excellent "The staff was friendly and the room was clean " [](https://expedia.com/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![Comfort Inn & Suites Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg) ### Comfort Inn & Suites Durham near Duke University 10/10 Excellent "Room was spotless. Staff was very helpful during check. I didn’t get to enjoy the " [](https://expedia.com/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![Fenced-No Steps-Pets-DownTown-Fast Wi-fi-Super Kitchen](https://images.trvl-media.com/lodging/33000000/32660000/32658000/32657945/94a5bca0_y.jpg) ### Fenced-No Steps-Pets-DownTown-Fast Wi-fi-Super Kitchen 10/10 Excellent "We had a magnificent stay! Jim and Donna are great hosts. The lodgings were as good as pictured. We had a small dog with us and the fenced in backyard was perfect! Bed was very comfortable. Great kitchen. Convenient to great pizza, restaurants and Duke. The only negative was no doubt our own lack of knowledge because we couldn’t figure out how to get the channels on the television that we were seeking. We joked that we needed our nephew there with us to decipher LOL" [](https://expedia.com/Raleigh-Hotels-No-Steps-Pets-DownTown-Fast-Wi-Fi-Super-Kitchen.h32657945.Hotel-Information) ![21c Museum Hotel Durham](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/a66cf407_y.jpg) ### 21c Museum Hotel Durham 10/10 Excellent "Really friendly, helpful staff. The room was so great and quiet, even next to the elevators." [](https://expedia.com/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) ![Everything within 1 mile](https://images.trvl-media.com/lodging/114000000/113150000/113141300/113141300/3c5dfb0c_y.jpg) ### Everything within 1 mile 10/10 Excellent "Host was great and place was great!!!" [](https://expedia.com/Raleigh-Hotels-Super-Cozy-Conv-Everything-Within-1-Mile.h113141300.Hotel-Information) ![Hampton Inn & Suites Durham/North I-85](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/cecacec2_y.jpg) ### Hampton Inn & Suites Durham/North I-85 10/10 Excellent "Room was very clean, breakfast was great and staff were kind and helpful." [](https://expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) ![Unscripted Durham, Part of JDV by Hyatt](https://images.trvl-media.com/lodging/19000000/18030000/18023800/18023733/0f9d6f74_y.jpg) ### Unscripted Durham, Part of JDV by Hyatt 10/10 Excellent "Loved how centrally located this hotel is, loved acted to the parking garage without having to take an elevator, loved it in general. Thanks!" [](https://expedia.com/Raleigh-Hotels-Unscripted-Durham.h18023733.Hotel-Information) ## Hotels near other Museum of Life and Science attractions ### Brightleaf Square You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657772) ### Vietnam Veterans Living Memorial You can find out about the history of Durham with a visit to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886205) ### Northgate Mall You can find the perfect gifts to bring home at Northgate Mall during your trip to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886206) ### Duke Homestead Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657783) ### Manbites Dog Theater You can make plans for a show at Manbites Dog Theater during your trip to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886210) ### Fullsteam Brewery You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886207) ### Durham Convention Center 4.2/5 (44 reviews) Learn about the events happening at Durham Convention Center during your trip to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657774) ### African American Dance Ensemble You can enjoy some culture when you stop by African American Dance Ensemble in Durham. [See properties](https://www.expedia.com/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=658956701486178304) ## Find out more about Museum of Life and Science ### Top reasons to visit Museum of Life and Science - **Engaging Exhibits:** Discover interactive science exhibits that captivate visitors of all ages. - **Beautiful Nature Trails:** Enjoy scenic walking paths that enhance your museum experience. - **Family-Friendly Activities:** Participate in various activities designed for families, ensuring fun for everyone. - **Local Events:** Experience the vibrant local culture with events like the Durham Art Walk. - **Diverse Accommodations:** Choose from a range of nearby lodging options, from cozy motels to upscale hotels. ### Find great hotels near Museum of Life and Science Experience a comfortable stay near the Museum of Life and Science in Durham, North Carolina, where a variety of lodging options await. From cozy motels to upscale hotels, you'll find accommodations that cater to business travelers, pet owners, and the LGBTQIA community. Enjoy convenient access to the museum and explore the diverse range of room rates and amenities that make your visit enjoyable and memorable. - **[HomeTowne Studios by Red Roof Raleigh - Durham: ](https://www.expedia.com/Raleigh-Hotels-HomeTowne-Studios-By-Red-Roof-Raleigh-Durham.h119192.Hotel-Information)** Emphasizing comfort and inclusivity, HomeTowne Studios by Red Roof Raleigh - Durham is a welcoming choice for LGBTQIA travelers. Located 9 miles from the Museum of Life and Science, this property offers a homey atmosphere with essential amenities for a relaxed stay. Each studio is equipped with kitchen facilities, making it ideal for extended visits. Guests appreciate the friendly staff and the commitment to creating an inclusive environment, ensuring that everyone feels at home during their stay. - **[Red Roof Inn Durham - Duke Univ Medical Center: ](https://www.expedia.com/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information)** Perfectly situated just 1 mile from the Museum of Life and Science, Red Roof Inn Durham - Duke Univ Medical Center caters to families, pet owners, and LGBTQIA travelers alike. This property is designed with families in mind, offering complimentary cribs and window guards for children. With a pet-friendly policy that allows dogs and cats, your furry friends are welcome too. Guests rave about the convenience and comfort, making it an excellent choice for those seeking an enjoyable family vacation. - **[La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill: ](https://www.expedia.com/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information)** This business-themed hotel, located 6 miles from the Museum of Life and Science, is ideal for business travelers while also welcoming pets. La Quinta Inn & Suites features multiple meeting rooms, a business center, and conference space, providing everything you need for a productive stay. Guests enjoy spacious rooms with modern amenities and appreciate the pet-friendly policy. The hotel’s convenient location near Chapel Hill ensures you are close to both business and leisure activities during your visit. ### Where to stay near Museum of Life and Science Your visit to the Museum of Life and Science in Durham, North Carolina, promises an enriching experience for the entire family. Just a few miles from downtown Durham, you'll find family-friendly hotels and charming neighborhoods. Explore the science park and nearby attractions that highlight the area's historical significance while enjoying the welcoming atmosphere of friendly locals. Whether you're on a budget or seeking unique experiences, Durham's vibrant culture and attractions will make your trip unforgettable. - **[Raleigh: ](https://www.expedia.com/Raleigh-Hotels.d178300.Travel-Guide-Hotels)** As the vibrant capital of North Carolina, Raleigh offers a dynamic blend of culture, education, and outdoor adventures. The Museum of Life and Science is nestled within its borders, making it an ideal starting point for exploring the city. Visitors are drawn to Raleigh year-round, with peak travel occurring from May to July. The city boasts numerous attractions, including modern universities, sports venues, and lively shopping malls. Whether you're attending a concert at an arena or enjoying a family outing at a local park, Raleigh provides a rich urban experience filled with cultural activities and entertainment options. - **[Durham: ](https://www.expedia.com/Durham-Hotels.d6049.Travel-Guide-Hotels)** Known for its historic charm and diverse community, Durham is a city that celebrates its heritage and innovation. The Museum of Life and Science is located here, making it a must-visit for families and city explorers alike. Travel peaks in March to April and September, attracting visitors to its educational institutions, shopping centers, and theaters. Highlights include the picturesque lakes and vibrant neighborhoods that enhance the city's charm. Durham's blend of urban and natural attractions offers a unique experience, inviting you to delve into its culinary scene or enjoy a performance at a local theater. - **[Duke Park: ](https://www.expedia.com/Duke-Park-Raleigh-Hotels.0-n553248635976477139-0.Travel-Guide-Filter-Hotels)** Situated just a mile from the Museum of Life and Science, Duke Park is a quaint neighborhood that encapsulates the essence of local culture. Visitors flock to this area throughout the year, with the summer months seeing the highest numbers. The neighborhood is perfect for those looking for a cultural experience, featuring arts centers, theaters, and educational venues. Highlights include the close proximity to modern universities and sports facilities, offering a vibrant atmosphere filled with community events and recreational opportunities. Explore the charming streets of Duke Park for a taste of local life. ### Things to do near Museum of Life and Science At the Museum of Life and Science in Durham, North Carolina, you can explore engaging exhibits and enjoy the beautiful nature trails that surround the museum. Don't miss local events, including the Durham Art Walk, and make use of the picnic areas for a relaxing meal outdoors. Additionally, the vibrant sports, festivals, and live music scene nearby adds to the excitement of your visit. **Shopping** The closest shopping center is [Northgate Mall](https://www.expedia.com/Northgate-Mall-Hotels.0-l553248621564886206-0.Travel-Guide-Filter-Hotels), just 0.9 miles from the Museum of Life and Science, featuring a variety of shops and entertainment. If you're up for a drive, visit [Brier Creek Commons](https://www.expedia.com/Brier-Creek-Commons-Hotels.0-l553248633876878645-0.Travel-Guide-Filter-Hotels), located 11 miles away, offering more shopping options and family-friendly vibes. **Recreation** Enjoy a game at [Durham Bulls Athletic Park](https://www.expedia.com/Durham-Bulls-Athletic-Park-Hotels.0-l6066243-0.Travel-Guide-Filter-Hotels), where the lively sports atmosphere energizes your spirit. For a leisurely day, head to [West Point on the Eno](https://www.expedia.com/West-Point-On-The-Eno-Hotels.0-l553248621532657784-0.Travel-Guide-Filter-Hotels) for tranquil nature walks and relaxation amidst beautiful scenery. Don't miss the [Duke University Golf Club](https://www.expedia.com/Duke-University-Golf-Club-Hotels.0-l553248621532657766-0.Travel-Guide-Filter-Hotels) for a refreshing round of golf. **Adventure** [Wheels Fun Park](https://www.expedia.com/Wheels-Fun-Park-Hotels.0-l553248621532657777-0.Travel-Guide-Filter-Hotels) offers thrilling karting experiences 3 miles from the Museum of Life and Science, perfect for adrenaline seekers. Ambler Tennis Stadium, also 3 miles away, provides an adventurous atmosphere for tennis enthusiasts. For a scenic hike, explore the North Carolina Civil War Trail, located 4 miles from the museum. **Nightlife** The nightlife near the Museum of Life and Science is vibrant and diverse. [Carolina Theatre](https://www.expedia.com/Carolina-Theatre-Hotels.0-l6066237-0.Travel-Guide-Filter-Hotels) and [Manbites Dog Theater](https://www.expedia.com/Manbites-Dog-Theater-Hotels.0-l553248621564886210-0.Travel-Guide-Filter-Hotels), both 2 miles away, offer cultural and romantic performances. For adventure seekers, [Frankie's Fun Park](https://www.expedia.com/Frankies-Fun-Park-Hotels.0-l6141662-0.Travel-Guide-Filter-Hotels), located 10 miles away, provides thrilling arcade games and excitement for the whole family. \*Distances are measured in a straight line; actual driving distances may vary depending on the route. ### Booking tips and Expedia advantages for Museum of Life and Science To save money on your trip to the Museum of Life and Science, consider visiting in July or December to January when prices are lower, and aim for a Monday stay, as Saturdays are pricier. Use Expedia to customize your travel plans, filter for eco-friendly hotels, and take advantage of package deals that combine flights and accommodations. Join Expedia's One Key membership for exclusive discounts and OneKeyCash rewards for future bookings. Also, explore free activities and utilize public transport to minimize travel costs during your visit. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay around Museum of Life and Science are July and December to January, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay around Museum of Life and Science is Monday. The most expensive day to stay around Museum of Life and Science is Saturday. - **Find cheap hotels on Expedia:** Take advantage of Expedia's search tool to customize your travel preferences, such as your budget, desired location, and preferred hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly accommodations that are currently available. To find the best prices and deals, simply sort the price filter from low to high. - **Consider bundling your trip:** You can save money by combining your hotel stay at the Museum of Life and Science with your flights and activities through an Expedia package deal. - **Become a One Key member:** Join [Expedia's One Key membership](https://www.expedia.com/welcome-one-key) program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels. ### Find the best attractions near Museum of Life and Science Whether you're interested in culture, outdoor experiences, or family fun, the Museum of Life and Science in Durham, North Carolina offers a variety of attractions. Explore nearby colleges and historic sports stadiums, or stroll through charming neighborhoods. Don't forget to check out nearby hotels and art museums to enhance your visit. With so much to see and do, your trip will be filled with memorable experiences. - **[Duke University: ](https://www.expedia.com/Duke-University-Hotels.0-l6066239-0.Travel-Guide-Filter-Hotels)** Explore the stunning Gothic architecture and beautiful gardens of Duke University, located 3 miles from the Museum of Life and Science. This vibrant campus offers a blend of modern and historical charm, perfect for a leisurely stroll. - **[Durham Performing Arts Center: ](https://www.expedia.com/Durham-Performing-Arts-Center-Hotels.0-l6301058-0.Travel-Guide-Filter-Hotels)** Immerse yourself in the local arts scene at the Durham Performing Arts Center, just 3 miles away. This cultural hub hosts a variety of performances, from Broadway shows to concerts, making it a lively spot for entertainment enthusiasts. - **[Research Triangle Park: ](https://www.expedia.com/Research-Triangle-Park-Hotels.0-l9677-0.Travel-Guide-Filter-Hotels)** Experience the innovation of Research Triangle Park, located 8 miles away. This thriving community is known for its tech developments and beautiful green spaces, offering a unique glimpse into the region's entrepreneurial spirit. ### The nearest major airports for your trip to Museum of Life and Science When planning a visit to the Museum of Life and Science in Durham, North Carolina, the closest major airport is Raleigh-Durham International Airport ([RDU](https://www.expedia.com/Raleigh-Durham-Intl-Airport-Hotels.0-aRDU-0.Travel-Guide-Filter-Hotels)), located 12 miles away. Nearby hotel options include [The Umstead Hotel and Spa](https://www.expedia.com/Raleigh-Hotels-The-Umstead-Hotel-And-Spa.h1563626.Hotel-Information), a luxurious 5-star resort just 3 miles from the airport, and [The Westin Raleigh-Durham Airport](https://www.expedia.com/Raleigh-Hotels-The-Westin-Raleigh-Durham-Airport.h78514258.Hotel-Information), a comfortable 4-star hotel only 2 miles away. Another option is the [DoubleTree by Hilton Raleigh Crabtree Valley](https://www.expedia.com/Raleigh-Hotels-DoubleTree-By-Hilton-Raleigh-Crabtree-Valley.h25703.Hotel-Information), situated 7 miles from RDU. For those considering Danville Regional Airport ([DAN](https://www.expedia.com/Danville-Regional-Airport-Hotels.0-aDAN-0.Travel-Guide-Filter-Hotels)), located 45 miles away, the [Courtyard by Marriott Danville](https://www.expedia.com/Danville-Hotels-Courtyard-By-Marriott-Danville.h918523.Hotel-Information), 4 miles from the airport, and [Sleep Inn & Suites Danville Hwy 58](https://www.expedia.com/Danville-Hotels-Sleep-Inn-Suites-Danville-Hwy-58.h919608.Hotel-Information), just 0.5 miles away, offer convenient accommodations. ## Frequently asked questions ### What are the top-rated hotels near Museum of Life and Science? > [Morehead Manor B&B](https://www.expedia.com/Raleigh-Hotels-Morehead-Manor-Bed-And-Breakfast.h37872342.Hotel-Information) > > > Morehead Manor B&B, a beautifully rated 3.5-star hotel, is located just 3.2 miles from the Museum of Life and Science and boasts an impressive review rating of 10\. Guests can indulge in a complimentary full breakfast each morning and enjoy the tranquil garden setting. The historical charm of the manor is complemented by amenities such as cozy bathrobes and daily housekeeping, ensuring a relaxing and memorable visit. > > > [Lil' Bull Bungalow- walk to Duke, Downtown Durham & Food](https://www.expedia.com/Raleigh-Hotels-Lil-Bull-Bungalow-Walk-To-Duke.h70584548.Hotel-Information) > > > Lil' Bull Bungalow offers an exceptional stay just 3.2 miles from the Museum of Life and Science, with a perfect review rating of 10\. This charming hotel features both indoor and outdoor pools, a fitness center nearby, and a fully equipped kitchen ideal for travelers looking to dine in. The inviting patio and balcony spaces allow travelers to enjoy the outdoors, while amenities like air conditioning and a secured yard enhance the comfort of their stay. > > > [Tiny Home in the Bull City-Walk to Duke Hospital](https://www.expedia.com/Raleigh-Hotels-Tiny-Home-In-The-Bull-City-Walk-To-Duke-Hospital.h102698297.Hotel-Information) > > > Tiny Home in the Bull City provides a unique and cozy experience, located 3.6 miles from the Museum of Life and Science, with a perfect review rating of 10\. This hotel includes a well-equipped kitchen and a lovely patio area for travelers to unwind. The nearby shopping and winery tours add to the appeal, making it a great choice for travelers seeking both adventure and comfort. ### How much is a hotel near Museum of Life and Science? ### What are the most popular family-friendly hotels near Museum of Life and Science? > [Hilton Durham near Duke University](https://www.expedia.com/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information) > > > Hilton Durham near Duke University is a family-friendly 3.5-star hotel located just 4.6 miles from the Museum of Life and Science. With a travelers' rating of 8.4, this hotel offers essential amenities for families, including free cribs and connecting rooms. Guests can enjoy the outdoor pool, on-site restaurant featuring kids' meals, and complimentary breakfast for children. Additional perks include a fitness center and free self-parking, making it a convenient choice for families. > > > [Hampton Inn & Suites Durham/North I-85](https://www.expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) > > > Hampton Inn & Suites Durham/North I-85 is a highly-rated family-friendly hotel, just 1.2 miles from the Museum of Life and Science, with an impressive travelers' rating of 9.0\. This hotel offers easy access to family-friendly amenities, including free buffet breakfast and indoor pool with accessibility features. Guests can take advantage of connecting rooms and convenient microwave access in their rooms. With a fitness center and free self-parking, it's an ideal choice for families visiting the area. > > > [Unscripted Durham, Part of JDV by Hyatt](https://www.expedia.com/Raleigh-Hotels-Unscripted-Durham.h18023733.Hotel-Information) > > > Unscripted Durham, Part of JDV by Hyatt is a vibrant 3.5-star hotel located only 2.9 miles from the Museum of Life and Science. Rated at 8.4 by travelers, this hotel is perfect for families, providing amenities like free cribs and a daily breakfast for children. Guests can relax at the outdoor pool, enjoy the convenience of housekeeping, and unwind at the rooftop terrace. The hotel also features a fitness center and a poolside bar, ensuring a fun and comfortable experience for families. ### What are the best affordable hotels near Museum of Life and Science? > [Lil' Bull Bungalow- walk to Duke, Downtown Durham & Food](https://www.expedia.com/Raleigh-Hotels-Lil-Bull-Bungalow-Walk-To-Duke.h70584548.Hotel-Information) > > > Lil' Bull Bungalow is an inviting retreat just 3.2 miles from the Museum of Life and Science, with a perfect review rating of 10\. This charming home features a well-equipped kitchen, making it ideal for families looking to prepare their own meals. Guests can enjoy relaxing on the balcony or by the shared outdoor pool, and the hotel also offers air conditioning and secured yard space for added comfort. > > > [Tiny Home in the Bull City-Walk to Duke Hospital](https://www.expedia.com/Raleigh-Hotels-Tiny-Home-In-The-Bull-City-Walk-To-Duke-Hospital.h102698297.Hotel-Information) > > > Tiny Home in the Bull City offers a uniquely cozy experience, located 3.6 miles from the Museum of Life and Science with a stellar review rating of 10\. Perfect for families, this home includes a fully equipped kitchen and a patio for outdoor dining. Guests can take advantage of nearby shopping and antiquing, and the hotel provides essential amenities like WiFi to keep everyone connected. > > > [Home2 Suites By Hilton Durham University Medical Center](https://www.expedia.com/Raleigh-Hotels-Home2-Suites-By-Hilton-Durham-University-Medical-Center.h92816797.Hotel-Information) > > > Home2 Suites By Hilton Durham University Medical Center, just 4.3 miles from the Museum of Life and Science, is a top-rated 3-star hotel with a fantastic review rating of 9.8\. Families will appreciate the free breakfast and access to an indoor pool. This hotel also features a fitness center and complimentary WiFi, making it an excellent choice for a comfortable and convenient stay. ### What are the best boutique hotels near Museum of Life and Science? > [The Durham Hotel](https://www.expedia.com/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information) > > > The Durham Hotel is a stylish 4-star boutique hotel located just 2.9 miles from the Museum of Life and Science, with an impressive review rating of 9.0\. Guests can enjoy the rooftop terrace, fitness facilities available 24 hours, and complimentary designer toiletries. With its romantic ambiance and premium bedding, The Durham Hotel ensures a memorable stay. ### Are there any hotels with pools close to Museum of Life and Science? > [Lil' Bull Bungalow- walk to Duke, Downtown Durham & Food](https://www.expedia.com/Raleigh-Hotels-Lil-Bull-Bungalow-Walk-To-Duke.h70584548.Hotel-Information) > > > A charming option located 3.2 miles from the Museum of Life and Science, Lil' Bull Bungalow boasts a perfect 10 review rating. This unique stay features both indoor and outdoor shared pools, allowing travelers to relax in a serene environment. With a fully equipped kitchen and a cozy patio, this bungalow is perfect for families or groups looking for a home-away-from-home experience while enjoying all that Durham has to offer. > > > [Hampton Inn & Suites Durham/North I-85](https://www.expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) > > > Just 1.2 miles from the Museum of Life and Science, the Hampton Inn & Suites is a highly-rated hotel with a perfect 9.0 review rating. This family-friendly hotel features an indoor pool equipped with accessible facilities, ideal for a refreshing dip after a day of exploration. Guests can enjoy complimentary buffet breakfast and 24-hour fitness facilities, ensuring a convenient and comfortable stay. > > > [Unscripted Durham, Part of JDV by Hyatt](https://www.expedia.com/Raleigh-Hotels-Unscripted-Durham.h18023733.Hotel-Information) > > > Located just 2.9 miles from the Museum of Life and Science, Unscripted Durham is a stylish 3.5-star hotel that features an inviting outdoor pool complete with sun loungers and a poolside bar. Rated 8.4 by travelers, this family-friendly hotel offers a 24-hour fitness center and free cribs for younger travelers, ensuring a comfortable stay for families. Guests can also enjoy the rooftop terrace, making it a great choice for relaxation after a day of adventures. ### What are the best pet-friendly hotels near Museum of Life and Science? > [Home2 Suites By Hilton Durham University Medical Center](https://www.expedia.com/Raleigh-Hotels-Home2-Suites-By-Hilton-Durham-University-Medical-Center.h92816797.Hotel-Information) > > > Home2 Suites By Hilton Durham University Medical Center is a stylish 3-star hotel just 4.3 miles from the Museum of Life and Science, featuring a remarkable travelers' rating of 9.8\. This pet-friendly hotel offers spacious suites with kitchen amenities, making it ideal for longer stays. Guests can enjoy a free breakfast, access to an indoor pool, and 24-hour fitness facilities, creating a cozy feel for both travelers and their furry companions. > > > [Hampton Inn & Suites Durham University Medical Center](https://www.expedia.com/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information) > > > Hampton Inn & Suites Durham University Medical Center stands out with an impressive travelers' rating of 9.6 and is situated 4.3 miles from the Museum of Life and Science. This hotel is pet-friendly, welcoming both dogs and cats, and offers a free buffet breakfast to start the day right. Guests can enjoy an indoor pool, 24-hour fitness facilities, and easy access to nearby attractions, ensuring a comfortable and enjoyable stay for the whole family. > > > [Red Roof Inn Durham - Duke Univ Medical Center](https://www.expedia.com/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) > > > Red Roof Inn Durham - Duke Univ Medical Center is a budget-friendly option located just 1.5 miles from the Museum of Life and Science, offering an inviting atmosphere for both pets and their owners. With a travelers' rating of 6.8, this hotel allows pets in rooms and provides essential amenities including free self-parking and daily housekeeping. Families will appreciate the free crib service and complimentary toiletries, making it a convenient choice for a family getaway. ### Can I book a fully refundable hotel close to Museum of Life and Science? ### Can I find Expedia discounts for hotels near Museum of Life and Science? > *\*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.* ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Durham Hotels ](https://www.expedia.com/Durham-Hotels.d6049.Travel-Guide-Hotels) - [Hotels near Duke Regional Hospital ](https://www.expedia.com/Duke-Regional-Hospital-Hotels.0-l553248633992437561-0.Travel-Guide-Filter-Hotels) - [Hotels near Northgate Mall ](https://www.expedia.com/Northgate-Mall-Hotels.0-l553248621564886206-0.Travel-Guide-Filter-Hotels) - [Hotels near Duke Park ](https://www.expedia.com/Duke-Park-Raleigh-Hotels.0-n553248635976477139-0.Travel-Guide-Filter-Hotels) - [Hotels near Duke Homestead ](https://www.expedia.com/Duke-Homestead-Hotels.0-l553248621532657783-0.Travel-Guide-Filter-Hotels) - [Hotels near 9th Street District ](https://www.expedia.com/Ninth-Street-Hotels.0-l6343384-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Durham ](https://www.expedia.com/Durham-Hotels-Cheap-Hotels.0-0-d6049-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels near Duke University Hospital ](https://www.expedia.com/Duke-University-Hospital-Hotels.0-l553248633992437540-0.Travel-Guide-Filter-Hotels) - [Hotels near Duke University ](https://www.expedia.com/Duke-University-Hotels.0-l6066239-0.Travel-Guide-Filter-Hotels) - [Hotels near Durham Convention Center ](https://www.expedia.com/Durham-Convention-Center-Hotels.0-l553248621532657774-0.Travel-Guide-Filter-Hotels) - [Hotels near Brightleaf Square ](https://www.expedia.com/Brightleaf-Square-Hotels.0-l553248621532657772-0.Travel-Guide-Filter-Hotels) - [Hotels near Carolina Theatre ](https://www.expedia.com/Carolina-Theatre-Hotels.0-l6066237-0.Travel-Guide-Filter-Hotels) - [Hotels near Durham Performing Arts Center ](https://www.expedia.com/Durham-Performing-Arts-Center-Hotels.0-l6301058-0.Travel-Guide-Filter-Hotels) - [Hotels near Durham Station ](https://www.expedia.com/Durham-Station-Hotels.d6194828.Travel-Guide-Hotels) - [Hotels near Downtown Durham ](https://www.expedia.com/Downtown-Durham-Raleigh-Hotels.0-n553248635976479661-0.Travel-Guide-Filter-Hotels) - [Extended Stay Hotels in Durham ](https://www.expedia.com/Durham-Hotels-Extended-Stay-Hotels.0-0-d6049-tExtendedStayHotels.Travel-Guide-Filter-Hotels) - [Hotels near Durham Bulls Athletic Park ](https://www.expedia.com/Durham-Bulls-Athletic-Park-Hotels.0-l6066243-0.Travel-Guide-Filter-Hotels) - [Hotels near Durham VA Medical Center ](https://www.expedia.com/Durham-VA-Medical-Center-Hotels.0-l6164731-0.Travel-Guide-Filter-Hotels) - [Hotels near American Tobacco Campus ](https://www.expedia.com/American-Tobacco-Campus-Hotels.0-l553248621563220390-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Durham ](https://www.expedia.com/5Star-Durham-Hotels.s50-0-d6049.Travel-Guide-Filter-Hotels) - [Hotels near Nasher Museum of Art at Duke University ](https://www.expedia.com/Nasher-Museum-Of-Art-At-Duke-University-Hotels.0-l553248621532657768-0.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Durham ](https://www.expedia.com/Durham-Hotels-Pet-Friendly-Hotel.0-0-d6049-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with an Indoor Pool in Durham ](https://www.expedia.com/Durham-Hotels-Hotels-With-Indoor-Pool.0-0-d6049-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Motels in Durham ](https://www.expedia.com/Durham-Motels.d6049-aaMotels.Travel-Guide-Accommodation) - [Hotels near Sarah P. 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