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Book Cape Girardeau Bed & Breakfast

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  • Check prices for these dates

    Check prices for these dates, December 13 – 14, 2026

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    Our top choices for Cape Girardeau bed & breakfast

    1. Makanda Inn

    A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Learn more about Cape Girardeau

    Explore the mighty Mississippi from the riverfront park where historic murals tell stories of river life. Climb to the top of Academic Hall at Southeast Missouri State or hunt for antiques along downtown's brick-paved streets.

    See all hotels in Cape Girardeau

    A nighttime view of a bridge with its cables illuminated against a starry sky.

    Frequently Asked Questions

    What is the nightly rate for a Bed and Breakfast in Cape Girardeau?

    Prices for B&Bs in Cape Girardeau often vary, but you can find a great deal from $298 with Expedia. All sorts of factors affect price, such as location and the time of year. It usually costs more to stay at Cape Girardeau B&Bs over the weekend too. Travelers can find the best deals by being flexible with their dates, and by using our filters to sort prices from low to high.

    When is the best time to book a Bed and Breakfast in Cape Girardeau?

    The best time to book a B&B in Cape Girardeau is during the vibrant spring months of April to June. This period showcases the city’s lively atmosphere as flowers bloom, and outdoor events begin to flourish, making it an ideal time for travelers seeking both adventure and relaxation. With temperatures ranging from the mid-50s to the low 80s Fahrenheit, visitors can comfortably explore local attractions, such as the scenic Riverfront and the historic downtown area, great for leisurely strolls and sightseeing.

    April brings a delightful mix of mild weather and blooming landscapes, making it an especially charming time to visit. The city hosts various festivals and events during this season, providing opportunities to engage with the local culture and enjoy delicious regional cuisine. Travelers can also take advantage of Cape Girardeau's picturesque parks, where hiking and picnicking become enjoyable pastimes in the pleasant spring air.

    For those considering budget-friendly options, visiting in December can be a wise choice. While this month may be quieter, it is filled with holiday cheer, offering unique festivities and a chance to experience the community's warm hospitality during the winter season.

    What is the difference between a Cape Girardeau B&B and a hotel?

    Every Cape Girardeau B&B has its own unique feel. Whether it’s a cozy reading space or a sunlit breakfast nook to enjoy your morning cup of coffee, the quaint details are what make bed and breakfasts a home away from home. Travelers can look forward to personal touches, thoughtful amenities and of course a scrumptious breakfast at Cape Girardeau B&Bs.

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