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Recommended hotels in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1007)
"Great place and staff, very accommodating!"
United States
Megan
$90 nightly
The price is $102
Dec 28 - Dec 29
Total with taxes and fees
Drury Plaza Hotel Cape Girardeau Conference Center

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (474)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
$96 nightly
The price is $109
Dec 22 - Dec 23
Total with taxes and fees
The Riverview

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (141)
"Nice hotel, clean and comfortable "
United States
Laura
$88 nightly
The price is $99
Dec 28 - Dec 29
Total with taxes and fees
Fairfield Inn & Suites by Marriott Cape Girardeau

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
$70 nightly
The price is $79
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Cape Girardeau Near the Medical Center

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
$91 nightly
The price is $103
Jan 4 - Jan 5, 2026
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (103)
"It was a nice stay"
United States
Douglas
$89 nightly
The price is $102
Jan 1 - Jan 2, 2026
Total with taxes and fees
Tru By Hilton Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
$116 nightly
The price is $131
Jan 1 - Jan 2, 2026
Total with taxes and fees
Courtyard by Marriott Cape Girardeau Downtown

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (785)
"Excellent stay"
United States
Christina
$102 nightly
The price is $115
Dec 27 - Dec 28
Total with taxes and fees
Hampton Inn Cape Girardeau I 55 East

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
"Very friendly staff and great breakfast"
United States
Ray
$90 nightly
The price is $102
Dec 26 - Dec 27
Total with taxes and fees
Drury Inn & Suites Cape Girardeau

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (686)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
$58 nightly
The price is $65
Dec 28 - Dec 29
Total with taxes and fees
Quality Inn Cape Girardeau North

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (884)
"Room was clean and spacious."
United States
George
$77 nightly
The price is $92
Jan 19 - Jan 20, 2026
Total with taxes and fees
Candlewood Suites Cape Girardeau by IHG

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
$150 nightly
The price is $170
Dec 28 - Dec 29
Total with taxes and fees
Rockwood Inn

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau
9.4 out of 10, Exceptional, (45)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
United States
Jordan S.
$132 nightly
The price is $138
Dec 22 - Dec 23
Total with taxes and fees
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
"Great stay"
United States
Heather
$70 nightly
The price is $79
Dec 28 - Dec 29
Total with taxes and fees
Pear Tree Inn Cape Girardeau West

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.6 out of 10, Excellent, (36)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
$209 nightly
The price is $217
Dec 23 - Dec 24
Total with taxes and fees
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (28)
"The place was awesome very clean the host was very accommodating. Nice a quiet for a relaxing stay highly recommend "
United States
Gary C.
$299 nightly
The price is $312
Dec 28 - Dec 29
Total with taxes and fees
The Twisted Sassafras Treehouse

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (149)
"Such a great place and location"
United States
Tracy H.
$229 nightly
The price is $245
Dec 22 - Dec 23
Total with taxes and fees
Serenity South -- Gardens, River-Views, and Refreshing Space

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (3)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
$310 nightly
The price is $310
Dec 22 - Dec 23
Total with taxes and fees
Gorgeous 1856 Log Cabin, Completely Renovated

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
$198 nightly
The price is $198
Dec 22 - Dec 23
Total with taxes and fees
The Cottage, Rusted Route Farms

Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.0 out of 10, Wonderful, (2)
"Unique property, plenty of space. Worked well for overnight stopover."
United States
Arthur S.
$310 nightly
The price is $310
Jan 5 - Jan 6, 2026
Total with taxes and fees
Beautifully Renovated Farmhouse in Jackson, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Find out more about Cape Girardeau

Cape Girardeau B&B information

Number of reviews
8,821
Accommodation
5 B&B
Lowest Price
$65
Highest Price
$312

Frequently asked questions

What is the nightly rate for a Bed and Breakfast in Cape Girardeau?
Prices for B&Bs in Cape Girardeau often vary, but you can find a great deal from $65 with Expedia. All sorts of factors affect price, such as location and the time of year. It usually costs more to stay at Cape Girardeau B&Bs over the weekend too. Travelers can find the best deals by being flexible with their dates, and by using our filters to sort prices from low to high.
When is the best time to book a Bed and Breakfast in Cape Girardeau?
The best time to book a B&B in Cape Girardeau is during the vibrant spring months of April to June. This period showcases the city's lively atmosphere as flowers bloom, and outdoor events begin to flourish, making it an ideal time for travelers seeking both adventure and relaxation. With temperatures ranging from the mid-50s to the low 80s Fahrenheit, visitors can comfortably explore local attractions, such as the scenic Riverfront and the historic downtown area, great for leisurely strolls and sightseeing.

April brings a delightful mix of mild weather and blooming landscapes, making it an especially charming time to visit. The city hosts various festivals and events during this season, providing opportunities to engage with the local culture and enjoy delicious regional cuisine. Travelers can also take advantage of Cape Girardeau's picturesque parks, where hiking and picnicking become enjoyable pastimes in the pleasant spring air.

For those considering budget-friendly options, visiting in December can be a wise choice. While this month may be quieter, it is filled with holiday cheer, offering unique festivities and a chance to experience the community's warm hospitality during the winter season.
What is the difference between a Cape Girardeau B&B and a hotel?
Every Cape Girardeau B&B has its own unique feel. Whether it's a cozy reading space or a sunlit breakfast nook to enjoy your morning cup of coffee, the quaint details are what make bed and breakfasts a home away from home. Travelers can look forward to personal touches, thoughtful amenities and of course a scrumptious breakfast at Cape Girardeau B&Bs.

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