Photo by Bill Dillard

Search Inns in Southeast Missouri

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Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3
No exact matches found, but these alternatives could be just right

Recommended hotels in Southeast Missouri

A motel with a covered entrance, a flag, and a phone number.

1. Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (314 reviews)
"Nice and clean friendly staff"
United States
Bawan
$88 nightly
The price is $96
Nov 6 - Nov 7
Total with taxes and fees
Madison Inn Lodge
A dining area with tables and chairs, a kitchen area, and a TV mounted on the wall.

2. Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,001 reviews)
"Our room was spacious, clean and the bed was super comfortable!"
Canada
Kim
$54 nightly
The price is $62
Nov 11 - Nov 12
Total with taxes and fees
Baymont Inn and Suites by Wyndham Farmington, MO
A modern kitchen with a coffee machine, a refrigerator, and a microwave.

3. Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (690 reviews)
"Clean nice staff are great"
United States
Marisa
$60 nightly
The price is $68
Nov 15 - Nov 16
Total with taxes and fees
Super 8 by Wyndham Farmington
A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

4. Hampton Inn & Suites By Hilton Festus

Hampton Inn & Suites By Hilton Festus
Festus
9.4 out of 10, Exceptional, (22 reviews)
"This was a wonderful hotel and had a wonderful stay. Room was clean and staff was wonderful."
United States
Misty
$112 nightly
The price is $128
Nov 15 - Nov 16
Total with taxes and fees
Hampton Inn & Suites By Hilton Festus
A reception area with a modern design, featuring a decorative wall piece, a small table with a bowl, and a patterned partition.

5. Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (445 reviews)
"We stayed one night and it was great! Breakfast was delicious."
United States
January
$114 nightly
The price is $132
Nov 15 - Nov 16
Total with taxes and fees
Holiday Inn Express & Suites Farmington by IHG
A spacious lobby with a reception desk, seating area, and large windows.

6. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,000 reviews)
"Clean, great food, excellent staff."
United States
Dean
$90 nightly
The price is $102
Nov 13 - Nov 14
Total with taxes and fees
Drury Inn & Suites Poplar Bluff
An indoor swimming pool with clear water, surrounded by lounge chairs and a tiled floor.

7. Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (582 reviews)
"The staff were so friendly & housekeeping came in each day to take care of our room. The breakfast was one of the best we have had. We had a great stay. Thank you to the staff!"
United States
Charlie
$105 nightly
The price is $120
Dec 4 - Dec 5
Total with taxes and fees
Hampton Inn Farmington
A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.

8. Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.2 out of 10, Wonderful, (338 reviews)
"Clean room, wifi easy to connect to, parking right in front."
United States
Jonathan
$137 nightly
The price is $150
Nov 6 - Nov 7
Total with taxes and fees
Shepherd Mountain Inn
An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.

9. Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
8.8 out of 10, Excellent, (702 reviews)
"Tucked away gem."
United States
christopher
$101 nightly
The price is $116
Nov 19 - Nov 20
Total with taxes and fees
Crown Pointe Lodge, BW Signature Collection
A hotel room with two beds, a desk, a chair, a TV, and a lamp.

10. Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (190 reviews)
"Clean rooms , nice pool."
United States
richard
$125 nightly
The price is $137
Nov 6 - Nov 7
Total with taxes and fees
Fort Davidson Hotel
A living room with a sofa, coffee table, and a small table with a vase. There is a window with blinds and a door in the background.

11. Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
2.0 star property
Bonne Terre
7.0 out of 10, Good, (590 reviews)
"Very clean and friendly place to stay."
United States
Elizabeth
$61 nightly
The price is $67
Nov 8 - Nov 9
Total with taxes and fees
Super 8 by Wyndham Bonne Terre
A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

12. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (976 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
United States
ELAINE
$97 nightly
The price is $109
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Poplar Bluff
A cabin surrounded by a natural forest setting with a fire pit and outdoor seating.

13. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
10.0 out of 10, Exceptional, (119 reviews)
"Recomend this location"
United States
Jose
$133 nightly
The price is $151
Nov 29 - Nov 30
Total with taxes and fees
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A spacious cafe with wooden tables and chairs, large windows, and a bar area.

14. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (804 reviews)
"Always an enjoyable stay"
United States
Nathan
$79 nightly
The price is $89
Dec 5 - Dec 6
Total with taxes and fees
Holiday Inn Poplar Bluff by IHG
A hotel lobby with a reception desk, seating area, and a patterned carpet.

15. Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (645 reviews)
"Excellent stay , couldn't believe the property was 10 years old , it looks like it was just built , great place , highly recommend ."
United States
allan p.
$101 nightly
The price is $116
Nov 15 - Nov 16
Total with taxes and fees
Holiday Inn Express & Suites Perryville by IHG
A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

16. Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,000 reviews)
"The hotel was clean, comfortable and the breakfast was good."
United States
Leonardo
$80 nightly
The price is $85
Nov 15 - Nov 16
Total with taxes and fees
Drury Inn & Suites Jackson MO
A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

17. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (1,009 reviews)
"Everything was great about the stay!"
United States
Denise
$89 nightly
The price is $100
Dec 6 - Dec 7
Total with taxes and fees
Hampton Inn Poplar Bluff
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

18. The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (702 reviews)
"Great property"
United States
John
$105 nightly
The price is $119
Nov 12 - Nov 13
Total with taxes and fees
The Riverview
A living room with a blue wall, a fireplace, a sofa, and a chair.

19. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.4 out of 10, Exceptional, (117 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
United States
Jan
$117 nightly
The price is $127
Nov 8 - Nov 9
Total with taxes and fees
EC Reed's Mercantile and Hotel
A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

20. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (890 reviews)
"Breakfast was good."
United States
J
$80 nightly
The price is $86
Nov 8 - Nov 9
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri
A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard
Open Photo by Bill Dillard

Top reviews in Southeast Missouri

A cabin surrounded by a natural forest setting with a fire pit and outdoor seating.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
French Village

10/10 Excellent

Limpio,muy fácil el check in cómodo y limpio.
United States
Dixon
Reviewed November 2, 2026
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

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