Top 10 Hotels in Frohna, MO (from $63) 2026 - Competitive Prices

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Our top choices for Frohna hotels

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

1. Drury Inn & Suites Jackson MO

Jackson

Lyn

$80 nightly

$85 total

Oct 28 - Oct 29

Total with taxes and fees

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

2. Super 8 by Wyndham Perryville

Perryville

Matthew

$68 nightly

$78 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel lobby with a reception desk, seating area, and a patterned carpet.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.

A reception area with a counter, vending machines, and a security camera.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

3. Holiday Inn Express & Suites Perryville by IHG

Perryville

Perry

$95 nightly

$109 total

Nov 22 - Nov 23

Total with taxes and fees

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$80 nightly

$86 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A swimming pool with a metal ladder, a Days Inn sign, and a blue water tower in the background.

A kitchen with wooden cabinets, a dining area with a table and chairs, and various kitchen appliances.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

5. Days Inn by Wyndham Perryville

Perryville

Jesse

$68 nightly

$77 total

Oct 25 - Oct 26

Total with taxes and fees

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A modern retail area with a display of local items and snacks.

6. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

$89 nightly

$102 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

7. Comfort Suites Jackson-Cape Girardeau

Jackson

Jeff

$76 nightly

$82 total

Nov 15 - Nov 16

Total with taxes and fees

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

8. Quality Inn Cape Girardeau North

Cape Girardeau

Dayanita

$59 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel room with a desk, a television, a coffee maker, a chair, and a window with curtains.

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

A breakfast bar with a toaster, coffee maker, and fruit juice dispenser.

9. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

$64 nightly

$73 total

Nov 15 - Nov 16

Total with taxes and fees

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

10. The Atrium - A Boutique Hotel

Perryville

Brian

$98 nightly

$112 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A gym with treadmills, a weight machine, and exercise balls.

A modern bathroom with a large bathtub, a wooden floor, and a dark wall with a colorful abstract painting.

A room with a fireplace, a mounted deer head, a bookshelf, and two armchairs.

11. Baymont by Wyndham Chester IL

Chester

Keng

$80 nightly

$89 total

Nov 22 - Nov 23

Total with taxes and fees

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A playground with a wooden playhouse, a slide, and two animal-shaped swings.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

12. Perryville RV Resort

Perryville

Kevin

$74 nightly

$84 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

A breakfast station with a flat-screen display, a pancake maker, and a coffee machine.

A conference room with tables, chairs, a flat-screen TV, and a sign indicating amenities.

13. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

Lauren

$103 nightly

$114 total

Nov 23 - Nov 24

Total with taxes and fees

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A hotel room with two beds, a wooden dresser, a bathroom with a shower, and a kitchen area.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

14. Town House Inn

Jackson

Jennifer

$75 nightly

$81 total

Oct 25 - Oct 26

Total with taxes and fees

A room with a brown sofa, a brown armchair, a patterned carpet, a lamp, and a window with curtains.

A hotel lobby with a reception desk, several tables and chairs, framed pictures on the walls, and a clock.

A hotel with a Super 8 sign, multiple parking spaces, and a brick facade.

A hotel room with a large bed, a desk, a chair, a window with curtains, a wall-mounted TV, and a large painting.

15. Super 8 by Wyndham Carbondale

Carbondale

Jeff

$65 nightly

$75 total

Nov 23 - Nov 24

Total with taxes and fees

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

A spacious lobby with a central seating area, a large window, and a reception desk.

A hotel with a covered entrance, outdoor seating, and a flag.

A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher. There is a window providing natural light and a view of the outdoors.

16. Home2 Suites by Hilton Carbondale

Carbondale

Margaret

$111 nightly

$128 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, a lamp, and a painting on the wall.

An indoor swimming pool with clear blue water, a sunshade, and a seating area with chairs and a table.

A bar area with multiple stools, a bar counter, shelves of liquor bottles, and hanging pendant lights.

A modern restaurant with a bar area, multiple tables and chairs, and a kitchen in the background.

17. Best Western Saluki Inn

Carbondale

Bryan

$87 nightly

$99 total

Nov 22 - Nov 23

Total with taxes and fees

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A hallway with exposed brick walls, wooden flooring, and a white door.

A dining area with a brick wall, wooden furniture, and a pineapple centerpiece.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

18. Urban Lofts

Perryville

Grace

$295 nightly

$338 total

Oct 24 - Oct 25

Total with taxes and fees

A building with a covered entrance, a parking lot, and a tree.

A hotel lobby with leather sofas, a reception desk, an exit sign, and a view of the outdoors.

A hotel reception area with a reception desk, a TV, and a seating area with a sofa and table.

A hotel room with a bed, desk, chair, television, and a window with curtains.

19. Quality Inn Carbondale University area

Carbondale

Alma

$54 nightly

$63 total

Nov 23 - Nov 24

Total with taxes and fees

A log cabin with a wooden deck, a door, and a small window.

A large outdoor area with a pond, several wooden cabins, and a road.

A gravel path leading to a lake with cabins and a sign indicating Blue Line Resort.

A compact kitchen with wooden cabinets, a microwave, a trash bin, and a dining table with placemats.

20. Pet Friendly! Couples Retreat in Southern Illinois

Murphysboro

$212 nightly

$235 total

Oct 25 - Oct 26

Total with taxes and fees

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Top Frohna Hotel Reviews

Baymont by Wyndham Chester IL

10/10 Excellent

"Staff upgraded our room to the first floor and we appreciate that after a long day."

Drury Inn & Suites Jackson MO

10/10 Excellent

"We want to thank all the staff for making our stay wonderful. The check in an out, room, food (both breakfast and dinner), pool, dining area and popcorn was great. We always enjoy staying here. Stay blessed always!"

Super 8 by Wyndham Perryville

8/10 Good

"Staff was awesome and very helpful. Place was very clean."

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"LOVE the double bench available for 2 suitcases! Top notch, KUDOS on that little thing that meant so much to us as seniors. Breakfast was good, rooms were clean, restaurant was nice. An overall exceptional experience. This stay moved Holiday Inn Express up a few notches on my list."

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Quick clean and very helpful"

Quality Inn Carbondale University area

8/10 Good

"Room was dated but clean. Bed was comfortable. We were grateful for the help we received after a botched reservation at another hotel."

Home2 Suites by Hilton Carbondale

10/10 Excellent

"Location is steps away from main drag and SIU campus."

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

10/10 Excellent

"great little getaway"

Tru By Hilton Cape Girardeau

10/10 Excellent

"A new property that is very clean and well trained staff"

More cheap stays in Frohna

Super 8 by Wyndham Carbondale

1180 E Main St Carbondale IL

$65 nightly

$75 total

Nov 23 - Nov 24

Total with taxes and fees

Days Inn by Wyndham Perryville

1500 Liberty Street Perryville MO

$68 nightly

$77 total

Oct 25 - Oct 26

Total with taxes and fees

7/10 Good! (461 reviews)

Baymont by Wyndham Chester IL

2150 State Street Chester IL

$80 nightly

$89 total

Nov 22 - Nov 23

Total with taxes and fees

8.4/10 Very Good! (432 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

$89 nightly

$102 total

Nov 1 - Nov 2

Total with taxes and fees

9.6/10 Exceptional! (195 reviews)

Holiday Inn Express & Suites Perryville by IHG

2020 Jefferson St Perryville MO

$95 nightly

$109 total

Nov 22 - Nov 23

Total with taxes and fees

9.2/10 Wonderful! (639 reviews)

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

120 MUDDY MONSTER ROAD Murphysboro IL

$103 nightly

$114 total

Nov 23 - Nov 24

Total with taxes and fees

Hotels in Frohna with star-rating

Frequently asked questions

What are the best family hotels in Frohna?

For a family-friendly accommodation in Frohna, The Weber Farm - Enjoy a beautiful 100 acre farm. is an excellent choice.This highly-rated property, with a great 10.0 review score, is ideal for families looking for a spacious and engaging stay. It offers an outdoor play area, a playground, and a variety of games, books, and toys specifically for children, ensuring plenty of entertainment for younger guests. The inclusion of a kitchen is also a great convenience for families who prefer to prepare their own meals.

When is the best time to go to Frohna?

The best time to go to Frohna, Missouri, is during the spring (April to May) or fall (September to October) when the weather is mild and comfortable for outdoor activities.Spring brings pleasant temperatures and blooming landscapes, making it ideal for exploring the historic Saxon Lutheran Memorial and enjoying the scenic rural setting. It's a great time for those interested in photography or simply taking leisurely strolls through the historic grounds.Fall offers crisp air and beautiful autumn foliage, especially appealing for visitors who appreciate natural beauty and comfortable conditions for sightseeing.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Frohna.

How much is the nightly rate at a Frohna hotel?

Prices for hotels in Frohna often vary, but you can find a great deal from $63 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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Find hotels in Frohna, MO from $63

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Frohna

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Frohna hotels

1. Drury Inn & Suites Jackson MO

2. Super 8 by Wyndham Perryville

3. Holiday Inn Express & Suites Perryville by IHG

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

5. Days Inn by Wyndham Perryville

6. Tru By Hilton Cape Girardeau

7. Comfort Suites Jackson-Cape Girardeau

8. Quality Inn Cape Girardeau North

9. Quality Inn Perryville I-55

10. The Atrium - A Boutique Hotel

11. Baymont by Wyndham Chester IL

12. Perryville RV Resort

13. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

14. Town House Inn

15. Super 8 by Wyndham Carbondale

16. Home2 Suites by Hilton Carbondale

17. Best Western Saluki Inn

18. Urban Lofts

19. Quality Inn Carbondale University area

20. Pet Friendly! Couples Retreat in Southern Illinois

Top Frohna Hotel Reviews

Baymont by Wyndham Chester IL

Drury Inn & Suites Jackson MO

Super 8 by Wyndham Perryville

Holiday Inn Express & Suites Perryville by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Quality Inn Carbondale University area

Home2 Suites by Hilton Carbondale

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

Tru By Hilton Cape Girardeau

More cheap stays in Frohna

Super 8 by Wyndham Carbondale

Days Inn by Wyndham Perryville

Baymont by Wyndham Chester IL

Tru By Hilton Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Hotels in Frohna with star-rating

Frequently asked questions

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