Top 10 Hotels in Frohna, MO (from $67) 2026 - Competitive Prices

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Our top choices for Frohna hotels

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A hotel room with two beds, a brick wall, and a wooden headboard.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

1. Drury Inn & Suites Jackson MO

Jackson

Lyn

$80 nightly

$85 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A reception area with a counter, vending machines, and a security camera.

A modern dining area with high tables and chairs, a television screen, and a view of the outdoors through large windows.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a ceiling with recessed lighting.

2. Holiday Inn Express & Suites Perryville by IHG

Perryville

Perry

$101 nightly

$116 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

3. Super 8 by Wyndham Perryville

Perryville

Matthew

$68 nightly

$78 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

$80 nightly

$86 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel room with a large bed, a bathroom with a bathtub, and a mirror reflecting the room.

A hotel hallway with a patterned carpet, blue walls, and a sign indicating an office.

A kitchen with wooden cabinets, a dining area with a table and chairs, and various kitchen appliances.

A reception area with a blue couch, a wooden table with a vase of flowers, and a reception desk with a digital screen.

5. Days Inn by Wyndham Perryville

Perryville

Jesse

$68 nightly

$77 total

Nov 1 - Nov 2

Total with taxes and fees

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

6. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

$89 nightly

$102 total

Oct 29 - Oct 30

Total with taxes and fees

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

7. The Atrium - A Boutique Hotel

Perryville

Brian

$75 nightly

$86 total

Oct 22 - Oct 23

Total with taxes and fees

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

8. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

$76 nightly

$82 total

Nov 10 - Nov 11

Total with taxes and fees

A lobby with a TV, framed pictures, a plant, and patterned chairs.

A hotel reception desk with a sign that reads "Quality by Choice Hotels."

A breakfast bar with a toaster, coffee maker, and fruit juice dispenser.

A hotel room with a large bathtub, a bed with two pillows, a nightstand, and a wall-mounted lamp.

9. Quality Inn Perryville I-55

Perryville

Evelynmaryeka

$64 nightly

$73 total

Nov 10 - Nov 11

Total with taxes and fees

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

10. Quality Inn Cape Girardeau North

Cape Girardeau

Dayanita

$59 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

A rustic cabin-style lodging with a covered porch, picnic tables, and a fire pit.

A cabin interior with a kitchenette, a ceiling fan, a television, a sofa, and a window with blinds.

A lakeside RV resort with wooden cabins, a picnic area, and a reflection in the water.

A swimming pool with a small water slide, surrounded by lounge chairs and umbrellas.

11. Perryville RV Resort

Perryville

Kevin

$74 nightly

$84 total

Oct 27 - Oct 28

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

An indoor swimming pool with four lounge chairs and a metal ladder.

A buffet with various food items, including omelets and other dishes, with clear signage indicating the type of food.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

12. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

Lauren

$108 nightly

$120 total

Oct 29 - Oct 30

Total with taxes and fees

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A gym with treadmills, a weight machine, and exercise balls.

A modern bathroom with a large bathtub, a wooden floor, and a dark wall with a colorful abstract painting.

A breakfast area with a counter, seating, and kitchen appliances.

13. Baymont by Wyndham Chester IL

Chester

Keng

$80 nightly

$89 total

Nov 15 - Nov 16

Total with taxes and fees

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

14. Town House Inn

Jackson

Jennifer

$75 nightly

$81 total

Oct 27 - Oct 28

Total with taxes and fees

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

A wooden interior with a dining area, staircase, and a television mounted on the wall.

A two-story building with a balcony, a front door with a wreath, and a sign indicating a restaurant.

A kitchen with a large black sink, a window with a view of trees, and a microwave on the counter.

15. The Mediterranean House 1858

Perryville

$271 nightly

$310 total

Oct 22 - Oct 23

Total with taxes and fees

A room with a brown sofa, a brown armchair, a patterned carpet, a lamp, and a window with curtains.

A hotel with a Super 8 sign, multiple parking spaces, and a brick facade.

A hotel room with a large bed, a desk, a chair, a window with curtains, a wall-mounted TV, and a large painting.

A hotel room with a microwave, refrigerator, chair, and a window with curtains.

16. Super 8 by Wyndham Carbondale

Carbondale

Jeff

$65 nightly

$75 total

Nov 9 - Nov 10

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, a lamp, and a painting on the wall.

A modern hotel lobby with leather sofas, a flat-screen TV, and framed artwork on the walls.

A modern restaurant with a bar area, multiple tables and chairs, and a kitchen in the background.

An indoor swimming pool with clear blue water, a sunshade, and a seating area with chairs and a table.

17. Best Western Saluki Inn

Carbondale

Bryan

$91 nightly

$104 total

Nov 8 - Nov 9

Total with taxes and fees

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A spacious living area with a large window, a ceiling fan, and a kitchen area with modern appliances.

A hallway with exposed brick walls, wooden flooring, and a white door.

18. Urban Lofts

Perryville

Grace

$150 nightly

$172 total

Oct 22 - Oct 23

Total with taxes and fees

A building with a covered entrance, a parking lot, and a tree.

A hotel dining area with tables and chairs, a buffet counter, and a television mounted on the wall.

A hotel reception area with a reception desk, a TV, and a seating area with a sofa and table.

A hotel lobby with leather sofas, a reception desk, an exit sign, and a view of the outdoors.

19. Quality Inn Carbondale University area

Carbondale

Alma

$59 nightly

$67 total

Oct 27 - Oct 28

Total with taxes and fees

A wooden cabin with a front porch, a staircase, and a door.

A kitchen with wooden cabinets, a microwave, and a table with checkered placemats.

A spacious living area with a wooden dining table and chairs, a flat-screen TV mounted on the wall, and a kitchen in the background.

A wooden deck with a picnic table and a covered seating area in a park.

20. Pet Friendly! Countryside Couples Stay in Illinois

Murphysboro

$218 nightly

$242 total

Oct 22 - Oct 23

Total with taxes and fees

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Top Frohna Hotel Reviews

Quality Inn Carbondale University area

8/10 Good

"Room was dated but clean. Bed was comfortable. We were grateful for the help we received after a botched reservation at another hotel."

Home2 Suites by Hilton Carbondale

10/10 Excellent

"Location is steps away from main drag and SIU campus."

Drury Inn & Suites Jackson MO

10/10 Excellent

"Lots of parking , clean room ,beautiful atmosphere breakfast was good."

Super 8 by Wyndham Carbondale

10/10 Excellent

"had a very good nights sleep. a.c. worked great. in room coffee and refridgerator is a must for me and were greatly appreciated. very friendly staff."

Quality Inn Cape Girardeau North

10/10 Excellent

"I chose this motel due to it being close to the car rental agency I used and the bus stop for Greyhound. Sidewalks on Kingshighway would have helped but that is on the city of Cape Girardeau! :-}"

Amazing Lakeside hot tub, A-frame 3 King Beds, Shawnee Forest sleeps 2-6 Firepit

10/10 Excellent

"great little getaway"

Tru By Hilton Cape Girardeau

10/10 Excellent

"A new property that is very clean and well trained staff"

Best Western Saluki Inn

8/10 Good

"Our daughter goes to SIU Carbondale so we travel there often. When we do we stay at this hotel. The price is reasonable, and the hotel's quality is better than some other options in town. That said, the overall property (e.g., hallways, stairwells) needs a good cleaning. The bedding is clean and their complimentary breakfast is about typical for these hotels."

Holiday Inn Express & Suites Perryville by IHG

10/10 Excellent

"Very nice facility, great staff, overall wonderful experience"