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Our top choices for Lupus hotels

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
3.0 star property
Columbia
9.6 out of 10, Exceptional, (1,402 reviews)
"This hotel was fantastic! We will definitely stay again!!! Food and service were phenomenal! So easy and close to get on and off 70 to get to hotel We normally book with Hilton but this was an even better experience!"
United States
Susan
$94 nightly
The price is $106
Apr 26 - Apr 27
Total with taxes and fees
Drury Plaza Hotel Columbia East

Ramada by Wyndham Columbia

Ramada by Wyndham Columbia
2.5 star property
Columbia
7.6 out of 10, Good, (1,001 reviews)
"Clean room, courteous staff, good breakfast "
United States
Amy
$72 nightly
The price is $81
Apr 9 - Apr 10
Total with taxes and fees
Ramada by Wyndham Columbia

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.2 out of 10, Very Good, (736 reviews)
"Nice place to stay"
United States
Carla
$65 nightly
The price is $74
Apr 19 - Apr 20
Total with taxes and fees
Baymont by Wyndham Columbia, MO

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
8.8 out of 10, Excellent, (1,000 reviews)
"Great breakfast, great stay!!"
United States
Rebecca
$110 nightly
The price is $125
Apr 12 - Apr 13
Total with taxes and fees
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Tru By Hilton Columbia South

Tru By Hilton Columbia South
2.5 star property
Columbia
8.8 out of 10, Excellent, (13 reviews)
"Everything was clean and service was great. Would definitely stay here again. "
United States
Sarah
$109 nightly
The price is $124
Apr 28 - Apr 29
Total with taxes and fees
Tru By Hilton Columbia South

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1,228 reviews)
"Excellent stay"
United States
David
$90 nightly
The price is $102
Apr 19 - Apr 20
Total with taxes and fees
Wingate by Wyndham - Columbia

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,773 reviews)
"Clean room, excellent breakfast, indoor pool and jacuzzi with helpful, pleasant staff. "
United States
David
$87 nightly
The price is $98
Apr 28 - Apr 29
Total with taxes and fees
Country Inn & Suites by Radisson, Columbia, MO

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn
2.5 star property
Columbia
8.8 out of 10, Excellent, (1,287 reviews)
"Breakfast was hot and delish and the towels were long/oversized which I prefer. "
United States
Kaylee
$70 nightly
The price is $79
Apr 12 - Apr 13
Total with taxes and fees
Best Western Plus Columbia Inn

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.4 out of 10, Very Good, (984 reviews)
"Stay was good "
United States
Ladona
$77 nightly
The price is $87
Apr 9 - Apr 10
Total with taxes and fees
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.2 out of 10, (1,000 reviews)
"Really nice people "
United States
Billie jo
$52 nightly
The price is $59
Apr 12 - Apr 13
Total with taxes and fees
Super 8 by Wyndham Columbia East

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1,004 reviews)
"Clean room, good rate, and the evening meal/kickback was very nice. "
United States
Matt
$102 nightly
The price is $115
Apr 12 - Apr 13
Total with taxes and fees
Drury Inn & Suites Columbia Stadium Boulevard

Days Inn by Wyndham Boonville

Days Inn by Wyndham Boonville
2.0 star property
Boonville
6.0 out of 10, (1,003 reviews)
"Very relaxing and quiet stay and close to my jobs and shopping."
United States
Wendy
$42 nightly
The price is $47
Apr 12 - Apr 13
Total with taxes and fees
Days Inn by Wyndham Boonville

Wyndham Executive Center Columbia

Wyndham Executive Center Columbia
3.5 star property
Columbia
8.2 out of 10, Very Good, (1,003 reviews)
"Overall the place was really good"
United States
carl
$113 nightly
The price is $127
Apr 12 - Apr 13
Total with taxes and fees
Wyndham Executive Center Columbia

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (863 reviews)
"It is worth staying with an affordable price "
United States
AVINASH KUMAR
$62 nightly
The price is $70
Apr 12 - Apr 13
Total with taxes and fees
Quality Inn & Suites Columbia I-70

Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG
3.0 star property
Columbia
8.2 out of 10, Very Good, (1,001 reviews)
"Excellent everything! Mahala at the restaurant bar was amazing! Front desk Chris was GREAT! Very clean! Will definitely stay again. "
United States
david
$110 nightly
The price is $125
Apr 12 - Apr 13
Total with taxes and fees
Holiday Inn Columbia East by IHG

Comfort Suites Columbia - University Area

Comfort Suites Columbia - University Area
2.5 star property
Columbia
7.8 out of 10, Good, (975 reviews)
"Clean friendly and dependable."
United States
Sonia
$94 nightly
The price is $106
Apr 12 - Apr 13
Total with taxes and fees
Comfort Suites Columbia - University Area

Holiday Inn Express Boonville by IHG

Holiday Inn Express Boonville by IHG
2.5 star property
Boonville
8.6 out of 10, Excellent, (534 reviews)
"Clean, friendly staff, would stay again"
United States
Tracy
$140 nightly
The price is $156
Apr 12 - Apr 13
Total with taxes and fees
Holiday Inn Express Boonville by IHG

Hotel Frederick

Hotel Frederick
3.0 star property
Boonville
8.8 out of 10, Excellent, (936 reviews)
"The incredible breakfasts. The sincerity and graciousness of Linda and Ken. We have stayed there before and we will stay again."
United States
Rachel
$131 nightly
The price is $149
May 7 - May 8
Total with taxes and fees
Hotel Frederick

Quality Inn & Suites Boonville - Columbia

Quality Inn & Suites Boonville - Columbia
2.5 star property
Boonville
7.4 out of 10, Good, (598 reviews)
"Nice stay "
United States
Harry
$93 nightly
The price is $105
Apr 30 - May 1
Total with taxes and fees
Quality Inn & Suites Boonville - Columbia

Hampton Inn Columbia

Hampton Inn Columbia
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,002 reviews)
"Good staff and breakfast was good"
United States
Christopher L
$106 nightly
The price is $120
Apr 26 - Apr 27
Total with taxes and fees
Hampton Inn Columbia
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Frequently asked questions

When is the best time to go to Lupus?
The best time to visit Lupus, Missouri, is during the spring and fall months, specifically from April to early June and from September to October. These periods offer the most pleasant weather for exploring the area.

During spring, the landscape around Lupus comes alive with blooming wildflowers and lush greenery, making it ideal for outdoor activities like hiking and enjoying nature. The temperatures are generally mild, ranging from the 50s to 70s Fahrenheit, which is comfortable for daytime excursions.

Fall brings cooler temperatures and the vibrant colors of autumn foliage, creating a picturesque setting for scenic drives and walks. The weather typically remains dry and comfortable, with temperatures similar to spring.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lupus.
How can I save on a Lupus hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Lupus hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

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How much is the nightly rate at a Lupus hotel?
Prices for hotels in Lupus often vary, but you can find a great deal from $70 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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