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Our top choices for Lupus hotels

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
3.0 star property
Columbia
9.6 out of 10, Exceptional, (1,427 reviews)
"Enjoyed our stay The breakfast was excellent and the breakfast staff was amazing!"
United States
Mark
$94 nightly
The price is $106
May 3 - May 4
Total with taxes and fees
Drury Plaza Hotel Columbia East

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.4 out of 10, Very Good, (768 reviews)
"Nice place to stay"
United States
Carla
$63 nightly
The price is $71
May 7 - May 8
Total with taxes and fees
Baymont by Wyndham Columbia, MO

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.4 out of 10, Very Good, (995 reviews)
"The restaurant was great"
United States
Sharri
$76 nightly
The price is $86
May 7 - May 8
Total with taxes and fees
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,793 reviews)
"First time here and very happy with the stay!"
United States
Ellie
$85 nightly
The price is $96
May 5 - May 6
Total with taxes and fees
Country Inn & Suites by Radisson, Columbia, MO

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1,233 reviews)
"Very clean and friendly place to stay"
United States
Will
$89 nightly
The price is $100
May 7 - May 8
Total with taxes and fees
Wingate by Wyndham - Columbia

Ramada by Wyndham Columbia

Ramada by Wyndham Columbia
2.5 star property
Columbia
7.6 out of 10, Good, (1,001 reviews)
"Clean room, courteous staff, good breakfast "
United States
Amy
$68 nightly
The price is $77
May 7 - May 8
Total with taxes and fees
Ramada by Wyndham Columbia

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
8.8 out of 10, Excellent, (1,003 reviews)
"It was nice for a quick stay."
United States
Sierra
$114 nightly
The price is $129
May 10 - May 11
Total with taxes and fees
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Tru By Hilton Columbia South

Tru By Hilton Columbia South
2.5 star property
Columbia
8.6 out of 10, Excellent, (19 reviews)
"Everything was clean and service was great. Would definitely stay here again. "
United States
Sarah
$106 nightly
The price is $121
May 10 - May 11
Total with taxes and fees
Tru By Hilton Columbia South

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (880 reviews)
"It is worth staying with an affordable price "
United States
AVINASH KUMAR
$62 nightly
The price is $70
May 4 - May 5
Total with taxes and fees
Quality Inn & Suites Columbia I-70

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn
2.5 star property
Columbia
8.8 out of 10, Excellent, (1,303 reviews)
"Nice property, easy on/off the freeway, friendly staff."
United States
Anne
$68 nightly
The price is $77
May 7 - May 8
Total with taxes and fees
Best Western Plus Columbia Inn

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1,008 reviews)
"Amazing! The staff was fantastic and friendly. I didn’t have the breakfast but the staff and rooms were great. "
United States
Bryan
$102 nightly
The price is $115
May 3 - May 4
Total with taxes and fees
Drury Inn & Suites Columbia Stadium Boulevard

Days Inn by Wyndham Boonville

Days Inn by Wyndham Boonville
2.0 star property
Boonville
6.0 out of 10, (1,008 reviews)
"Parking was easy! "
United States
Melissa
$49 nightly
The price is $55
Apr 30 - May 1
Total with taxes and fees
Days Inn by Wyndham Boonville

Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.2 out of 10, (1,000 reviews)
"Very clean Comfortable bed Good tv Easy parking"
United States
THOMAS
$55 nightly
The price is $62
May 5 - May 6
Total with taxes and fees
Super 8 by Wyndham Columbia East

Wyndham Executive Center Columbia

Wyndham Executive Center Columbia
3.5 star property
Columbia
8.2 out of 10, Very Good, (1,001 reviews)
"Had a great stay"
United States
Damon
$107 nightly
The price is $121
May 3 - May 4
Total with taxes and fees
Wyndham Executive Center Columbia

Comfort Suites Columbia - University Area

Comfort Suites Columbia - University Area
2.5 star property
Columbia
7.8 out of 10, Good, (980 reviews)
"Clean friendly and dependable."
United States
Sonia
$98 nightly
The price is $111
May 5 - May 6
Total with taxes and fees
Comfort Suites Columbia - University Area

Midway Budget Inn

Midway Budget Inn
2.5 star property
Columbia
6.0 out of 10, (127 reviews)
"The room was clean and the towels were very soft "
United States
Tyler
$80 nightly
The price is $85
Apr 30 - May 1
Total with taxes and fees
Midway Budget Inn

Holiday Inn Express Boonville by IHG

Holiday Inn Express Boonville by IHG
2.5 star property
Boonville
8.6 out of 10, Excellent, (538 reviews)
"Clean, friendly staff, would stay again"
United States
Tracy
$155 nightly
The price is $173
May 3 - May 4
Total with taxes and fees
Holiday Inn Express Boonville by IHG

Hotel Frederick

Hotel Frederick
3.0 star property
Boonville
8.8 out of 10, Excellent, (943 reviews)
"beautifully restored, wonderful hospitality, great bar and restaurant!"
United States
ryon
$117 nightly
The price is $132
Apr 30 - May 1
Total with taxes and fees
Hotel Frederick

Hilton Garden Inn Columbia

Hilton Garden Inn Columbia
3.0 star property
Columbia
8.8 out of 10, Excellent, (544 reviews)
"I would stay here again. "
United States
Dean
$122 nightly
The price is $139
May 7 - May 8
Total with taxes and fees
Hilton Garden Inn Columbia

TownePlace Suites by Marriott Columbia

TownePlace Suites by Marriott Columbia
3.0 star property
Columbia
9.2 out of 10, Wonderful, (368 reviews)
"Pet friendly location with a quiet atmosphere for resting from a days driving."
United States
Ruth
$122 nightly
The price is $139
May 3 - May 4
Total with taxes and fees
TownePlace Suites by Marriott Columbia
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Frequently asked questions

When is the best time to go to Lupus?
The best time to visit Lupus, Missouri, is during the spring and fall months, specifically from April to early June and from September to October. These periods offer the most pleasant weather for exploring the area.

During spring, the landscape around Lupus comes alive with blooming wildflowers and lush greenery, making it ideal for outdoor activities like hiking and enjoying nature. The temperatures are generally mild, ranging from the 50s to 70s Fahrenheit, which is comfortable for daytime excursions.

Fall brings cooler temperatures and the vibrant colors of autumn foliage, creating a picturesque setting for scenic drives and walks. The weather typically remains dry and comfortable, with temperatures similar to spring.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lupus.
How can I save on a Lupus hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Lupus hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Lupus hotel?
Prices for hotels in Lupus often vary, but you can find a great deal from $55 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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