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Our top choices for Lupus hotels

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East
3.0 star property
Columbia
9.6 out of 10, Exceptional, (1,427 reviews)
"Enjoyed our stay The breakfast was excellent and the breakfast staff was amazing!"
United States
Mark
$94 nightly
The price is $106
May 10 - May 11
Total with taxes and fees
Drury Plaza Hotel Columbia East

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO
2.5 star property
Columbia
8.2 out of 10, Very Good, (773 reviews)
"Nice place to stay"
United States
Carla
$64 nightly
The price is $72
May 10 - May 11
Total with taxes and fees
Baymont by Wyndham Columbia, MO

Ramada by Wyndham Columbia

Ramada by Wyndham Columbia
2.5 star property
Columbia
7.6 out of 10, Good, (1,002 reviews)
"Clean room, courteous staff, good breakfast "
United States
Amy
$69 nightly
The price is $78
May 3 - May 4
Total with taxes and fees
Ramada by Wyndham Columbia

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG
2.5 star property
Columbia
8.8 out of 10, Excellent, (1,002 reviews)
"It was nice for a quick stay."
United States
Sierra
$114 nightly
The price is $129
May 7 - May 8
Total with taxes and fees
Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG

Tru By Hilton Columbia South

Tru By Hilton Columbia South
2.5 star property
Columbia
8.6 out of 10, Excellent, (19 reviews)
"Everything was clean and service was great. Would definitely stay here again. "
United States
Sarah
$106 nightly
The price is $121
May 17 - May 18
Total with taxes and fees
Tru By Hilton Columbia South

Best Western Plus Columbia Inn

Best Western Plus Columbia Inn
2.5 star property
Columbia
8.8 out of 10, Excellent, (1,305 reviews)
"Nice property, easy on/off the freeway, friendly staff."
United States
Anne
$70 nightly
The price is $79
May 10 - May 11
Total with taxes and fees
Best Western Plus Columbia Inn

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70
2.5 star property
Columbia
7.0 out of 10, Good, (884 reviews)
"It is worth staying with an affordable price "
United States
AVINASH KUMAR
$62 nightly
The price is $70
May 9 - May 10
Total with taxes and fees
Quality Inn & Suites Columbia I-70

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1,227 reviews)
"Very clean and friendly place to stay"
United States
Will
$85 nightly
The price is $96
May 10 - May 11
Total with taxes and fees
Wingate by Wyndham - Columbia

Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO
2.5 star property
Columbia
9.0 out of 10, Wonderful, (1,800 reviews)
"First time here and very happy with the stay!"
United States
Ellie
$87 nightly
The price is $98
May 24 - May 25
Total with taxes and fees
Country Inn & Suites by Radisson, Columbia, MO

Wyndham Executive Center Columbia

Wyndham Executive Center Columbia
3.5 star property
Columbia
8.2 out of 10, Very Good, (1,003 reviews)
"Had a great stay"
United States
Damon
$113 nightly
The price is $127
May 7 - May 8
Total with taxes and fees
Wyndham Executive Center Columbia

Drury Inn & Suites Columbia Stadium Boulevard

Drury Inn & Suites Columbia Stadium Boulevard
3.0 star property
Columbia
9.4 out of 10, Exceptional, (1,000 reviews)
"Amazing! The staff was fantastic and friendly. I didn’t have the breakfast but the staff and rooms were great. "
United States
Bryan
$102 nightly
The price is $115
May 10 - May 11
Total with taxes and fees
Drury Inn & Suites Columbia Stadium Boulevard

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination
3.0 star property
Boonville
8.4 out of 10, Very Good, (997 reviews)
"Casino and bar were nice. "
United States
Marcia
$77 nightly
The price is $87
Jun 1 - Jun 2
Total with taxes and fees
Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination

Hotel Blu

Hotel Blu
2.5 star property
Columbia
6.0 out of 10, (2 reviews)
"The location was good. The room was fairly quiet (I could hear a lot of walking above me at 2am...). It was clean and the staff was great. The TV wouldn't stay connected. I would watch about 30 seconds of the show and it would cut off...then power back on a few seconds later. I finally just turned it off and put a movie on my tablet. The door security latch was broken...like completely gone. So I wedged a chair under the door for extra piece of mind. There appeared to be a maxi pad paper...
United States
Margaret
$70 nightly
The price is $79
May 4 - May 5
Total with taxes and fees
Hotel Blu

Super 8 by Wyndham Columbia East

Super 8 by Wyndham Columbia East
2.0 star property
Columbia
6.2 out of 10, (1,000 reviews)
"Very clean Comfortable bed Good tv Easy parking"
United States
THOMAS
$55 nightly
The price is $62
May 10 - May 11
Total with taxes and fees
Super 8 by Wyndham Columbia East

Hilton Garden Inn Columbia

Hilton Garden Inn Columbia
3.0 star property
Columbia
8.8 out of 10, Excellent, (544 reviews)
"I would stay here again. "
United States
Dean
$122 nightly
The price is $139
May 9 - May 10
Total with taxes and fees
Hilton Garden Inn Columbia

Hotel Frederick

Hotel Frederick
3.0 star property
Boonville
8.8 out of 10, Excellent, (944 reviews)
"beautifully restored, wonderful hospitality, great bar and restaurant!"
United States
ryon
$125 nightly
The price is $141
May 5 - May 6
Total with taxes and fees
Hotel Frederick

Comfort Suites Columbia - University Area

Comfort Suites Columbia - University Area
2.5 star property
Columbia
7.8 out of 10, Good, (981 reviews)
"The staff was very attentive. The room was nice but the bathroom floor was not clean. I asked if they would clean it and they took care of it immediately. Overall a good stay."
United States
Jen
$89 nightly
The price is $101
May 3 - May 4
Total with taxes and fees
Comfort Suites Columbia - University Area

Holiday Inn Columbia East by IHG

Holiday Inn Columbia East by IHG
3.0 star property
Columbia
8.2 out of 10, Very Good, (1,001 reviews)
"Excellent everything! Mahala at the restaurant bar was amazing! Front desk Chris was GREAT! Very clean! Will definitely stay again. "
United States
david
$110 nightly
The price is $125
May 10 - May 11
Total with taxes and fees
Holiday Inn Columbia East by IHG

Hampton Inn & Suites Columbia at University

Hampton Inn & Suites Columbia at University
2.5 star property
Columbia
8.8 out of 10, Excellent, (1,003 reviews)
"Good breakfast options. Very friendly breakfast staff"
United States
Tom
$102 nightly
The price is $115
May 10 - May 11
Total with taxes and fees
Hampton Inn & Suites Columbia at University

Extended Stay America Select Suites - Columbia - Stadium Blvd.

Extended Stay America Select Suites - Columbia - Stadium Blvd.
2.5 star property
Columbia
7.0 out of 10, Good, (1,000 reviews)
"I only stayed overnight, so I didn't require any cooking equipment, but if I had, there would have been a deposit required for the equipment. The room was very clean, in very good shape with a comfortable bed. Shower was hot with a strong spray head, no shampoo, but I had my own. I would stay, again."
United States
Spencer
$80 nightly
The price is $90
May 3 - May 4
Total with taxes and fees
Extended Stay America Select Suites - Columbia - Stadium Blvd.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

When is the best time to go to Lupus?
The best time to visit Lupus, Missouri, is during the spring and fall months, specifically from April to early June and from September to October. These periods offer the most pleasant weather for exploring the area.

During spring, the landscape around Lupus comes alive with blooming wildflowers and lush greenery, making it ideal for outdoor activities like hiking and enjoying nature. The temperatures are generally mild, ranging from the 50s to 70s Fahrenheit, which is comfortable for daytime excursions.

Fall brings cooler temperatures and the vibrant colors of autumn foliage, creating a picturesque setting for scenic drives and walks. The weather typically remains dry and comfortable, with temperatures similar to spring.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lupus.
How can I save on a Lupus hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Lupus hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Lupus hotel?
Prices for hotels in Lupus often vary, but you can find a great deal from $57 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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