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Our top choices for Sedgewickville hotels

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (698 reviews)
"Conveniently located, clean, friendly staff."
United States
Philip
$84 nightly
The price is $91
Feb 8 - Feb 9
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (557 reviews)
"lean, updated rooms, friendly staff and great breakfast."
United States
Linda
$91 nightly
The price is $104
Feb 8 - Feb 9
Total with taxes and fees
Holiday Inn Express & Suites Perryville by IHG

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,005 reviews)
"Suited our purpose for overnight on a road trip "
United States
Angela
$80 nightly
The price is $85
Feb 8 - Feb 9
Total with taxes and fees
Drury Inn & Suites Jackson MO

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very Good, (949 reviews)
"Updated and very nice"
United States
Debbie
$70 nightly
The price is $80
Mar 2 - Mar 3
Total with taxes and fees
Super 8 by Wyndham Perryville

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (108 reviews)
"It was a nice stay"
United States
Douglas
$89 nightly
The price is $102
Feb 11 - Feb 12
Total with taxes and fees
Tru By Hilton Cape Girardeau

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (84 reviews)
"Cute room, great food, fun soda fountain and friendly owners! Will return! "
United States
Leslie
$85 nightly
The price is $93
Feb 10 - Feb 11
Total with taxes and fees
EC Reed's Mercantile and Hotel

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very Good, (740 reviews)
"Clean and comfortable every time. This is a “go to” hotel "
United States
Jacqulyn
$84 nightly
The price is $90
Feb 8 - Feb 9
Total with taxes and fees
Comfort Suites Jackson-Cape Girardeau

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (695 reviews)
"The room was clean and nice. The breakfast was really good."
United States
Kalani
$60 nightly
The price is $67
Feb 24 - Feb 25
Total with taxes and fees
Quality Inn Cape Girardeau North

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (420 reviews)
"Great people there"
United States
Trasea
$73 nightly
The price is $84
Feb 3 - Feb 4
Total with taxes and fees
Days Inn by Wyndham Perryville

Town House Inn

Town House Inn
2.5 star property
Jackson
7.6 out of 10, Good, (432 reviews)
"The staff member Tim was very friendly and nice. "
United States
Julie
$68 nightly
The price is $74
Feb 26 - Feb 27
Total with taxes and fees
Town House Inn

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (297 reviews)
"Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again."
United States
Steve
$77 nightly
The price is $84
Feb 3 - Feb 4
Total with taxes and fees
Madison Inn Lodge

Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.6 out of 10, (124 reviews)
"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
$75 nightly
The price is $86
Feb 9 - Feb 10
Total with taxes and fees
Quality Inn Perryville I-55

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17 reviews)
"Great place to stay! "
United States
Eric
$254 nightly
The price is $291
Feb 3 - Feb 4
Total with taxes and fees
Urban Lofts

Farm-style Ste. Genevieve Retreat w/ Fire Pit!

Farm-style Ste. Genevieve Retreat w/ Fire Pit!
3.0 star property
Ste Genevieve
Farm-style Ste. Genevieve Retreat w/ Fire Pit!

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
3.0 star property
Perryville
10.0 out of 10, Exceptional, (2 reviews)
"The house and host were just awesome, enjoyed our stay Toni even helped me Extend!! Would def stay again:)"
United States
Shandese
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin
3.0 star property
Perryville
Hot Tub & Creek Views: Secluded Perryville Cabin

Chic Ste Genevieve Home w/ Nice Interior Amenities

Chic Ste Genevieve Home w/ Nice Interior Amenities
3.0 star property
Ste Genevieve
Chic Ste Genevieve Home w/ Nice Interior Amenities

Missouri Castle w/ Private Lake, Pool & 100 Acres!

Missouri Castle w/ Private Lake, Pool & 100 Acres!
3.0 star property
St Mary
Missouri Castle w/ Private Lake, Pool & 100 Acres!

Private Getaway on 270 Acres w/ Lake: Swim & Canoe

Private Getaway on 270 Acres w/ Lake: Swim & Canoe
2.0 star property
Advance
Private Getaway on 270 Acres w/ Lake: Swim & Canoe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in Sedgewickville?
The best area to stay in Sedgewickville is the Downtown Historic District, which offers convenient access to local amenities and attractions.

This district is the heart of Sedgewickville, characterized by its well-preserved 19th-century architecture and a collection of locally-owned shops and eateries. Main Street, the central thoroughfare, features several historic buildings, including the Old Sedgewickville Courthouse and the Sedgewickville Historical Society Museum. Its compact size makes it very walkable, allowing visitors to explore on foot.

For couples looking for a relaxed getaway, the Downtown Historic District provides a pleasant setting. You'll find quaint bed and breakfasts and boutique accommodations, offering a quiet and intimate experience. The area's local restaurants and cafes are ideal for enjoying meals together, and evening strolls past historic landmarks are a nice way to spend time.

Families will also find the Downtown Historic District a good base. Its central location means easy access to the Sedgewickville Community Park, which has play areas and open spaces for children. The Sedgewickville Public Library, also in this district, often hosts family-friendly events.
When is the best time to go to Sedgewickville?
The best time to go to Sedgewickville is during the spring (April to June) and fall (September to October) months.

These seasons offer pleasant temperatures, making it ideal for exploring the outdoors and enjoying the town's offerings without the extreme heat of summer or the chill of winter. Spring brings blooming wildflowers and comfortable conditions for hiking the trails around the Castor River, while fall provides colorful foliage and crisp air great for scenic drives through the countryside.

Couples looking for a peaceful getaway will particularly appreciate spring and fall. The mild weather encourages leisurely strolls through the historic downtown, visits to local shops, and relaxed dining experiences.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Sedgewickville.
How can I save on a Sedgewickville hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Sedgewickville hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Sedgewickville hotel?
Prices for hotels in Sedgewickville often vary, but you can find a great deal from $67 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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