Title: TOP 10 Hotels in Sedgewickville, MO from $73 - Competitive Prices | Expedia.com [Sedgewickville Travel Guide](https://expedia.com/Sedgewickville.dx3000349537)[Vacation Rentals in Sedgewickville](https://expedia.com/Sedgewickville-Vacation-Rentals.d3000349537.Travel-Guide-VacationRentals)[Car Rentals in Sedgewickville](https://expedia.com/Car-Rentals-In-Sedgewickville.d3000349537.Car-Rental-Guide)[Sedgewickville Vacation Packages](https://expedia.com/Sedgewickville.d3000349537.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Sedgewickville Pet-friendly [](https://www.expedia.com/Hotel-Search?destination=Sedgewickville%2C+Missouri%2C+United+States+of+America®ionId=3000349537&latLong=37.516166%2C-89.907049&adults=2&startDate=2026-03-15&d1=2026-03-15&endDate=2026-03-17&d2=2026-03-17&amenities=PETS) Pool [](https://www.expedia.com/Hotel-Search?destination=Sedgewickville%2C+Missouri%2C+United+States+of+America®ionId=3000349537&latLong=37.516166%2C-89.907049&adults=2&startDate=2026-03-15&d1=2026-03-15&endDate=2026-03-17&d2=2026-03-17&amenities=POOL) Cabins [](https://www.expedia.com/Hotel-Search?destination=Sedgewickville%2C+Missouri%2C+United+States+of+America®ionId=3000349537&latLong=37.516166%2C-89.907049&adults=2&startDate=2026-03-15&d1=2026-03-15&endDate=2026-03-17&d2=2026-03-17&lodging=CABIN) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Sedgewickville%2C+Missouri%2C+United+States+of+America®ionId=3000349537&latLong=37.516166%2C-89.907049&adults=2&startDate=2026-03-15&d1=2026-03-15&endDate=2026-03-17&d2=2026-03-17&lodging=APARTMENT) ## Check prices for these dates Tonight [Mar 1 - Mar 2](https://www.expedia.com/Hotel-Search?regionId=3000349537&startDate=2026-03-01&endDate=2026-03-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 2 - Mar 3](https://www.expedia.com/Hotel-Search?regionId=3000349537&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=3000349537&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=3000349537&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Sedgewickville hotels ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2f374258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/0aa802d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/2e166a9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible, Bathtub (Mobility & Hearing)](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/1ca0c293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau [](https://www.expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) Cape Girardeau 9.6/10 Exceptional (113 reviews) "It was a nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas $98 nightly $111 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/a0829ae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/f646a9e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/c0aef459.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74670000/74660800/74660768/145de6a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EC Reed's Mercantile and Hotel [](https://www.expedia.com/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) Marble Hill 9.6/10 Exceptional (84 reviews) "Cute room, great food, fun soda fountain and friendly owners! Will return! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie $102 nightly $112 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Marble-Hill-Hotels-EC-Reeds-Mercantile-And-Hotel.h74660768.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c66d7d11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/44b66206.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/4ac4ba46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau North [](https://www.expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) Cape Girardeau 7.2/10 Good (702 reviews) "The room was clean and nice. The breakfast was really good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kalani $67 nightly $75 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2ba6efa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Accessible, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/46ce3d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/2abc797b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, 2 Queen Beds, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/affd3e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) Jackson 7.6/10 Good (438 reviews) "The staff member Tim was very friendly and nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie $67 nightly $73 total Mar 7 - Mar 8 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/db122c9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/622c9d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/5f391186.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/60000/60000/59960/765df2ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Madison Inn Lodge [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) Fredericktown 7.6/10 Good (297 reviews) "Room was not exactly smelling nice, but room was clean and comfortable. The lodge was close to expressway and shopping. Staff was very friendly. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve $88 nightly $96 total Mar 2 - Mar 3 Total with taxes and fees [](https://www.expedia.com/Farmington-Hotels-Madison-Inn-Lodge.h59960.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/8a502333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/0ac4753f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau [](https://www.expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) Jackson 8.2/10 Very Good (746 reviews) "Clean and comfortable every time. This is a “go to” hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacqulyn $88 nightly $96 total Mar 2 - Mar 3 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/dc7dee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/ccad2677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily self-serve breakfast](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/8447c54f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau [](https://www.expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) Jackson 9.0/10 Wonderful (714 reviews) "Conveniently located, clean, friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip $84 nightly $91 total Mar 4 - Mar 5 Total with taxes and fees [](https://www.expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/132cb18c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/b5f01af6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) Jackson 9.6/10 Exceptional (1,005 reviews) "Breakfast was great- staff was welcoming. Will stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura $80 nightly $85 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/469821a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/1d457549.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/0c87c756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/2b5bb07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Perryville by IHG [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) Perryville 9.2/10 Wonderful (561 reviews) "Staff was friendly and the place is clean. Our stay was in late January and the air was so very dry and the static electricity from blankets & sheets was off the charts." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger $103 nightly $118 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/0b4f194a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/586044dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Lofts [](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) Perryville 9.2/10 Wonderful (17 reviews) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $227 nightly $260 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information) ![Room, 1 King Bed | Jetted tub](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/6caf4858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/e7849830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/0ac21fcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) Perryville 6.8/10 (422 reviews) "Great people there" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Trasea $71 nightly $82 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Suite, 1 King Bed, Non Smoking (1 Bedroom) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/e270ba08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/504b77a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/807f3a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility Accessible) | In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/ef8850d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Perryville [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) Perryville 8.4/10 Very Good (958 reviews) "If you're looking for a great deal, this is it. Unlike many less expensive hotels, this one has been refreshed with new carpeting and paint. Staff was courteous and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Judith $68 nightly $78 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/01a032b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/0d3bba3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/26f852d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Perryville I-55 [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) Perryville 6.6/10 (126 reviews) "Room okay, no milk for cold cereal, Hot Tub outside-nothing on website about that" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anita $71 nightly $82 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![House](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/6077a455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/23df4d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/53673780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![](https://images.trvl-media.com/lodging/127000000/126620000/126618400/126618348/a7c17063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mediterranean House 1858 [](https://www.expedia.com/Perryville-Hotels-The-Mediterranean-House-1858.h126618348.Hotel-Information) Perryville $737 nightly $844 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Perryville-Hotels-The-Mediterranean-House-1858.h126618348.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-15&endDate=2026-03-16®ionId=3000349537&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_3000349537) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSedgewickville-Hotels.d3000349537.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSedgewickville-Hotels.d3000349537.Travel-Guide-Hotels) ## Top Sedgewickville Hotel Reviews ![Drury Inn & Suites Jackson MO](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "Friendly staff." [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41_y.jpg) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau 10/10 Excellent "Clean and spacous " [](https://expedia.com/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Beautiful Modern Loft In Wine Country!](https://images.trvl-media.com/lodging/24000000/23140000/23139500/23139432/86d734a8_y.jpg) ### Beautiful Modern Loft In Wine Country! 10/10 Excellent "We had a great time in Ste. G! Julia's loft is lovely. There were deer feeding at the pond the first morning, and ducks landing on the pond the following morning. You'll really feel like you're hundreds of miles away from everyone at this beautiful spot." [](https://expedia.com/Ste-Genevieve-Hotels-Beautiful-Modern-Loft-In-Wine-Country.h23139432.Hotel-Information) ![Town House Inn](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 10/10 Excellent "The room was amazing clean and no problems " [](https://expedia.com/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg) ### Holiday Inn Express & Suites Perryville by IHG 10/10 Excellent "Room was great, front desk was professional but friendly. Breakfast was excellent. Spotless — both room and lobby. " [](https://expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "New! Love the lobby layout, design and seating. Staff is super friendly and welcoming. Location is right next to the sports complex. " [](https://expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Comfort Suites Jackson-Cape Girardeau](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25_y.jpg) ### Comfort Suites Jackson-Cape Girardeau 10/10 Excellent "Overall the stay was amazing. Staff was nice easy to work with. Check in progress was fast and simple loved the location!! Quiet street had no issues at all. Definitely would stay again " [](https://expedia.com/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![The Twisted Sassafras Treehouse ](https://images.trvl-media.com/lodging/96000000/95880000/95879200/95879160/55527a20_y.jpg) ### The Twisted Sassafras Treehouse 10/10 Excellent "Great location , great view, awesome place" [](https://expedia.com/Cape-Girardeau-Hotels-The-Twisted-Sassafras-Treehouse.h95879160.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg) ### Super 8 by Wyndham Perryville 10/10 Excellent "The carpet in the room and halls looked new which says a lot. I would stay there again. " [](https://expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ## More cheap stays in Sedgewickville ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn 2011 North Kingshighway Cape Girardeau MO $67 nightly $75 total Mar 8 - Mar 9 Total with taxes and fees 7.2/10 Good! (702 reviews) [](https://expedia.com/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Super 8 by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/670000/664100/664059/f824aec9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Super 8 by Wyndham Perryville 1119 Vincent Dr Perryville MO $68 nightly $78 total Mar 8 - Mar 9 Total with taxes and fees 8.4/10 Very Good! (958 reviews) [](https://expedia.com/Perryville-Hotels-Super-8-By-Wyndham-Perryville.h664059.Hotel-Information) ![Quality Inn Perryville I-55](https://images.trvl-media.com/lodging/1000000/90000/85000/84949/bf2aa006_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Perryville I-55 1517 S. Perryville Blvd. Perryville MO $71 nightly $82 total Mar 8 - Mar 9 Total with taxes and fees 6.6/10 (126 reviews) [](https://expedia.com/Perryville-Hotels-Quality-Inn.h84949.Hotel-Information) ![Days Inn by Wyndham Perryville](https://images.trvl-media.com/lodging/1000000/20000/10400/10352/f6ab26a4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Perryville 1500 Liberty Street Perryville MO $71 nightly $82 total Mar 15 - Mar 16 Total with taxes and fees [](https://expedia.com/Perryville-Hotels-Days-Inn-By-Wyndham-Perryville.h10352.Hotel-Information) ![Tru By Hilton Cape Girardeau](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tru By Hilton Cape Girardeau 2520 Veterans Memorial Dr Cape Girardeau MO $98 nightly $111 total Mar 8 - Mar 9 Total with taxes and fees 9.6/10 Exceptional! (113 reviews) [](https://expedia.com/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Holiday Inn Express & Suites Perryville by IHG](https://images.trvl-media.com/lodging/21000000/20120000/20115400/20115319/68f46185_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Perryville by IHG 2020 Jefferson St Perryville MO $103 nightly $118 total Mar 22 - Mar 23 Total with taxes and fees 9.2/10 Wonderful! (561 reviews) [](https://expedia.com/Perryville-Hotels-Holiday-Inn-Express-Suites-Perryville.h20115319.Hotel-Information) ## Hotels in Sedgewickville with star-rating ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 1 properties [](https://expedia.com/4Star-Sedgewickville-Hotels.s40-0-d3000349537.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 10 properties [](https://expedia.com/3Star-Sedgewickville-Hotels.s30-0-d3000349537.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 17 properties [](https://expedia.com/2Star-Sedgewickville-Hotels.s20-0-d3000349537.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### What is the best area to stay in Sedgewickville? > This district is the heart of Sedgewickville, characterized by its well-preserved 19th-century architecture and a collection of locally-owned shops and eateries. Main Street, the central thoroughfare, features several historic buildings, including the Old Sedgewickville Courthouse and the Sedgewickville Historical Society Museum. Its compact size makes it very walkable, allowing visitors to explore on foot. > > > For couples looking for a relaxed getaway, the Downtown Historic District provides a pleasant setting. You'll find quaint bed and breakfasts and boutique accommodations, offering a quiet and intimate experience. The area's local restaurants and cafes are ideal for enjoying meals together, and evening strolls past historic landmarks are a nice way to spend time. > > > Families will also find the Downtown Historic District a good base. Its central location means easy access to the Sedgewickville Community Park, which has play areas and open spaces for children. The Sedgewickville Public Library, also in this district, often hosts family-friendly events. ### When is the best time to go to Sedgewickville? > These seasons offer pleasant temperatures, making it ideal for exploring the outdoors and enjoying the town's offerings without the extreme heat of summer or the chill of winter. Spring brings blooming wildflowers and comfortable conditions for hiking the trails around the Castor River, while fall provides colorful foliage and crisp air great for scenic drives through the countryside. > > > Couples looking for a peaceful getaway will particularly appreciate spring and fall. The mild weather encourages leisurely strolls through the historic downtown, visits to local shops, and relaxed dining experiences. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Sedgewickville hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Sedgewickville hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Friedheim Hotels ](https://www.expedia.com/Friedheim-Hotels.d3000349372.Travel-Guide-Hotels) - [Hotels near Perryville Country Club ](https://www.expedia.com/Perryville-Country-Club-Hotels.0-l553248621564822920-0.Travel-Guide-Filter-Hotels) - [Perryville Hotels ](https://www.expedia.com/Perryville-Hotels.d6134448.Travel-Guide-Hotels) - [Hotels near National Shrine of Our Lady of the Miraculous Medal ](https://www.expedia.com/National-Shrine-Of-Our-Lady-Of-The-Miraculous-Medal-Hotels.0-l553248621561876731-0.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Perryville ](https://www.expedia.com/Perryville-Cabins.d6134448-aaCabins.Travel-Guide-Accommodation) - [Motels in Perryville ](https://www.expedia.com/Perryville-Motels.d6134448-aaMotels.Travel-Guide-Accommodation) - 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