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Find 4 Star Hotels in Grand Center, MO from $111

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Dec 7 - Dec 8
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Dec 8 - Dec 9
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Dec 12 - Dec 14
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Dec 19 - Dec 21

Compare Grand Center 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1144)
"So pleased with my stay would definitely recommend! Affordable and exclusive, staff ensured my stay was immaculate!"
United States
Meli
$101 nightly
The price is $120
Dec 11 - Dec 12
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4.0 star property
Downtown St. Louis
8.4 out of 10, Very Good, (4012)
"Loved our stay. Great location and awesome view from room "
United States
Phillip
$95 nightly
The price is $111
Dec 21 - Dec 22
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
Lobby
Hilton St. Louis Frontenac

Hilton St. Louis Frontenac

4.0 star property
Frontenac
8.8 out of 10, Excellent, (1005)
"Clean room, felt like a mini apartment! The surrounding was beautiful. "
United States
Jane
$130 nightly
The price is $152
Dec 14 - Dec 15
Total with taxes and fees
Hilton St. Louis Frontenac
Interior
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1486)
"Room was perfect and parking was a breeze. We really enjoyed the art was wonderful. "
United States
London
$131 nightly
The price is $153
Dec 28 - Dec 29
Total with taxes and fees
21C Museum Hotel St Louis
Terrace/patio
The Cheshire

The Cheshire

4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1002)
"Excellent place to stay. "
United States
Todd
$115 nightly
The price is $137
Dec 29 - Dec 30
Total with taxes and fees
The Cheshire
Exterior
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

4.0 star property
Berkeley
8.4 out of 10, Very Good, (1054)
"Staff was courteous and the room was clean."
United States
Mia
$118 nightly
The price is $138
Dec 19 - Dec 20
Total with taxes and fees
Renaissance St. Louis Airport Hotel
Terrace/patio
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4.0 star property
Grand Center
8.8 out of 10, Excellent, (1035)
"This was a wonderful first experience at a beautiful hotel with such friendly staff. We will definitely stay here again!"
United States
Alexis
$119 nightly
The price is $141
Dec 14 - Dec 15
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1099)
"Great staff"
United States
Phillip
$149 nightly
The price is $177
Dec 14 - Dec 15
Total with taxes and fees
Live by Loews - St.Louis
Lounge
The Westin St. Louis

The Westin St. Louis

4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1002)
"Great location "
United States
Gregory
$127 nightly
The price is $148
Dec 14 - Dec 15
Total with taxes and fees
The Westin St. Louis
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very Good, (1001)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
$166 nightly
The price is $194
Dec 14 - Dec 15
Total with taxes and fees
Ameristar Casino Resort and Spa
In-room safe, desk, blackout drapes, iron/ironing board
DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park

4.0 star property
Central West End
8.2 out of 10, Very Good, (1003)
"Great room "
United States
Jessica
$114 nightly
The price is $134
Dec 21 - Dec 22
Total with taxes and fees
DoubleTree by Hilton St. Louis Forest Park
Daily cooked-to-order breakfast for a fee
River City Casino & Hotel

River City Casino & Hotel

4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1448)
"Awesome place to stay!!"
United States
Kaitlyn
$96 nightly
The price is $112
Dec 15 - Dec 16
Total with taxes and fees
River City Casino & Hotel
Lobby
St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton

4.0 star property
Downtown West
8.4 out of 10, Very Good, (1006)
"Nice historic hotel"
United States
Michelle
$142 nightly
The price is $169
Dec 14 - Dec 15
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton
Exterior
Marriott St. Louis Grand

Marriott St. Louis Grand

4.0 star property
Downtown St. Louis
8.2 out of 10, Very Good, (1001)
"Very convenient to the local sites we wanted to visit."
United States
Garland
$127 nightly
The price is $151
Dec 14 - Dec 15
Total with taxes and fees
Marriott St. Louis Grand
Exterior
Moonrise Hotel

Moonrise Hotel

4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1921)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
$158 nightly
The price is $188
Dec 22 - Dec 23
Total with taxes and fees
Moonrise Hotel
Lobby
Marriott St. Louis Airport

Marriott St. Louis Airport

4.0 star property
Edmundson
8.0 out of 10, Very Good, (1003)
"Love that there is a restaurant inside the property so that after you check in you do not have to go elsewhere to find a place to eat. "
United States
Susan
$128 nightly
The price is $152
Dec 19 - Dec 20
Total with taxes and fees
Marriott St. Louis Airport
Exterior
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1012)
"My second time staying there as always it was lovely "
United States
Nina
$103 nightly
The price is $122
Dec 19 - Dec 20
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch
Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, sun loungers
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4.0 star property
Clayton
8.8 out of 10, Excellent, (675)
"Small rooms but beautiful lobby. "
United States
Debbie
$119 nightly
The price is $140
Dec 19 - Dec 20
Total with taxes and fees
Le Méridien St. Louis Clayton
Interior
DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport

4.0 star property
Maryland Heights
8.2 out of 10, Very Good, (1002)
"Stayed one night felt very safe here"
United States
William
$110 nightly
The price is $127
Dec 28 - Dec 29
Total with taxes and fees
DoubleTree by Hilton St. Louis - Westport
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1241)
"Great hospitality"
United States
Alejandro
$107 nightly
The price is $128
Dec 14 - Dec 15
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Grand Center.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
$415 nightly
The price is $485 total per night from Jan 1 to Jan 2
$485 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
9.4/10 Exceptional! (1,002 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Grand Center Hotel Reviews

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent
"The staff was great !!!"
Daniel 2-night trip
Posted 1 day ago
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Frequently asked questions

What are the best 4-star hotels in Grand Center?
Angad Arts Hotel is one of our customers' favorite 4-star hotels around Grand Center. Concierge services and premium bedding are just the start of its many amenities. Another option that receives rave reviews for its excellent guest experience is St. Louis Union Station Hotel, Curio Collection by Hilton. Book your stay here and make use of premium bedding and a swimming pool.
How much does it cost to stay in a 4-star hotel in Grand Center?
We can help you quickly locate the perfect 4-star hotel for your getaway in Grand Center. Use our handy filter tool to fine-tune your search by things like amenities, budget and star rating and get access to fabulous deals in a couple of clicks.

  • Search for the lowest price from $485

What's the difference between 5-star and 4-star hotels in Grand Center?
If you decide to book a stay at a 4-star hotel in Grand Center, you'll typically find plenty of amenities to ensure you're comfortable, such as a restaurant, pool and gym. You can look forward to top-quality service and upscale accommodations. Pick a 5-star hotel and you'll get a few more perks — think on-site spas, 24-hour front desk and indulgent turndown services. You'll most likely get additional amenities and first-class services at a 5-star retreat, though both are fabulous options for luxury guests.

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