Find hotels in Guadalupe District, Santa Fe from $77
Go beyond your typical stay in Guadalupe District
Check prices for these dates
Discover 1,723 Guadalupe District hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Inn at Santa Fe, SureStay Collection by Best Western
Inn at Santa Fe, SureStay Collection by Best Western

Hampton Inn & Suites Los Alamos White Rock
Hampton Inn & Suites Los Alamos White Rock

The Mystic Santa Fe
The Mystic Santa Fe

Guadalupe Inn
Guadalupe Inn

Cottonwood Court Motel
Cottonwood Court Motel

Econo Lodge Inn & Suites
Econo Lodge Inn & Suites
Where to stay in Guadalupe District

Downtown Santa Fe
Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops, and acclaimed art galleries. You might also want to make some time to see Santa Fe Plaza or Lensic Performing Arts Center while you're exploring the neighborhood.
Southside
Southside is known for its popular shops, and with sights like Meow Wolf and International Museum of Collage, Assemblage & Construction, you won't get bored spending a day wandering around this part of Santa Fe.
Tesuque
Tesuque is noteworthy for its spas, and you can make a stop at top attractions like Shidoni Foundry and Glenn Green Galleries & Sculpture Garden.

Historic Eastside
While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Edition ONE Gallery.
Northeast Santa Fe
If you're looking for some top things to see and do in Northeast Santa Fe and surrounding area, you can visit Santa Fe Plaza and New Mexico Museum of Art.
Top Guadalupe District Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Santa Fe Hotels
- Hotels near Santa Fe Plaza
- Hotels near Downtown Santa Fe
- Hotels near West Manhattan
- Hotels near Santa Fe Depot
- Hotels near Santa Fe Railyard
- Hotels near Santa Fe River Park
- Cheap Hotels in Santa Fe
- Hotels near Santuario De Nuestra Senora de Guadalupe
- New Mexico Hotels
- Hotels near The Harrell House of Natural Oddities and Bug Museum
- Hotels near Lensic Performing Arts Center
- Hotels near Andrea Fisher Fine Pottery
- Hotels near New Mexico State Capitol
- Hotels near Georgia O'Keefe Museum
- Hotels near Santa Fe Climbing Gym
- Hotels near Loretto Chapel
- Resorts in Santa Fe Depot
- Guest Houses in Santa Fe Depot
- Cottages in Santa Fe Depot
- Hotels near New Mexico Museum of Art
- Santa Fe County Hotels
- Hotels near Palace of the Governors
- All-inclusive Resorts in New Mexico
- Casino Hotels in New Mexico
- Hotels near San Miguel Mission
- Hotels near De Vargas Street House
- Hotels near Institute of American Indian Arts
- Pet-friendly Hotels in Santa Fe
- Hotels near Museum of Contemporary Native Arts
- Hotels near Cathedral Basilica of Saint Francis of Assisi
- Hotels near Santa Fe National Cemetery
- Hotels near Santa Fe Symphony Orchestra and Chorus
- Luxury Hotels in Downtown Santa Fe
- Historic Hotels in Downtown Santa Fe
- Hotels near South Capitol
- 4 Star Hotels in Santa Fe
- Hotels near Nedra Matteucci Galleries
- Hotels with Suites in Downtown Santa Fe
- Extended Stay Hotels in Downtown Santa Fe
- B&B in Santa Fe
- Cabin Rentals in Santa Fe
- All-inclusive Resorts in Santa Fe
- Business Hotels in Downtown Santa Fe
- Hotels with Restaurants in Downtown Santa Fe
- Boutique Hotels in Downtown Santa Fe
- Pet-friendly Hotels in Downtown Santa Fe
- Resorts & Hotels with Spas in Downtown Santa Fe
- Hotels with Balconies in Downtown Santa Fe
- Hotels with Free Parking in Downtown Santa Fe
- 4 Star Hotels in Downtown Santa Fe
- Hotels with Bars in Downtown Santa Fe
- Adults Only Resorts & in Downtown Santa Fe
- Hotels with Hot Tubs in Downtown Santa Fe
- Hotels with Kitchenettes in Downtown Santa Fe
- 5 Star Hotels in Downtown Santa Fe
- Hotels with Connecting Rooms in Downtown Santa Fe
- Hotel Wedding Venues Hotels in Downtown Santa Fe
- Hotels with Fireplaces in Downtown Santa Fe
- Hotels with Laundry Facilities in Downtown Santa Fe
- All-inclusive Resorts in Downtown Santa Fe
- Ski Hotels in Downtown Santa Fe
- Hotels with an Indoor Pool in Downtown Santa Fe
- Hotels with Air Conditioning in Downtown Santa Fe
- Cheap Hotels in Downtown Santa Fe
- Hotel with a Concierge Hotels in Downtown Santa Fe
- Quiet Resorts & in Downtown Santa Fe
- Hotels with a Pool in Downtown Santa Fe
- Hotels with an Outdoor Pool in Downtown Santa Fe
- Hotels with a View in Downtown Santa Fe
- Romantic Hotels in Downtown Santa Fe
- Casino Hotels in Downtown Santa Fe
- Honeymoon Resorts & in Downtown Santa Fe
- Golf Hotels in Downtown Santa Fe
- Hotels with Tennis Courts in Downtown Santa Fe
- Hotels with a Gym in Downtown Santa Fe
- Family Hotels in Downtown Santa Fe
- 3 Star Hotels in Downtown Santa Fe
- Hotels with Room Service in Downtown Santa Fe
- Hotels with Free Breakfast in Downtown Santa Fe
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Hotels in top Santa Fe neighborhoods
- Hotels in Downtown Santa Fe
- Hotels in Southside
- Hotels in Tesuque
- Hotels in Historic Eastside
- Hotels in Northeast Santa Fe
- Hotels in North Hills
- Hotels in South Capitol
- Hotels in Don Diego
- Hotels in Railyard Arts District
- Hotels in San Mateo
- Hotels in Southeast Santa Fe
- Hotels in Guadalupe District
- Hotels in West Guadaloupe
- Hotels in Arroyo Chamisa
- Hotels in Casa Solana
- Hotels in Vista Encantada
- Hotels in West Manhattan
- Hotels in Las Campanas
- Hotels in La Cienaga
- Hotels in West Alameda
Hotels near popular Santa Fe Attractions
More Accommodation Types in Guadalupe District
- Vacation Homes in Santa Fe
- Condo Rentals in Santa Fe
- Apartments in Santa Fe
- Cottages in Santa Fe
- Guest Houses in Santa Fe
- B&B in Santa Fe
- Villas in Santa Fe
- Aparthotels in Santa Fe
- Motels in Santa Fe
- Resorts in Santa Fe
- Cabin Rentals in Santa Fe
- RV Parks in Santa Fe
- Chalets in Santa Fe
- Houseboats in Santa Fe
- Lodges in Santa Fe
Hotels Close to Nearby Airports
Guadalupe District Hotels by Star Rating
Explore more hotels
- Hilton Santa Fe Buffalo Thunder
- Hotel Glorieta
- La Posada de Santa Fe, A Tribute Portfolio Resort & Spa
- Las Palomas
- Hilton Vacation Club Villas de Santa Fe
- Hotel Chimayo de Santa Fe
- Inn on the Alameda
- Piñon Court By La Fonda
- La Quinta Inn by Wyndham Santa Fe
- Inn at Santa Fe, SureStay Collection by Best Western
- Fort Marcy Hotel Suites by All Seasons Resort Lodging
- Hotel Inn Santa Fe
Expedia's Latest Trends
- Southside Hotels
- Hotels near Santa Fe Railyard
- Hotels near Loretto Chapel
- Huning Highland Historic District Hotels
- Hotels near Meow Wolf
- Historic Hotels in Downtown Santa Fe
- Uptown Hotels
- Hotels near Canyon Road
- Extended Stay Hotels in Downtown Santa Fe
- Hotels with Suites in Downtown Santa Fe
- Business Hotels in Downtown Santa Fe
- South Capitol Hotels
- Downtown Albuquerque Hotels
- Downtown Santa Fe Hotels
- Old Town Albuquerque Hotels
- Hotels near Santa Fe Plaza
- Luxury Hotels in Downtown Santa Fe