$105 Cheap Flights from Missoula (MSO) to Chicago (ORD)

View $105 flight on Mon, Sep 29, 2025Opens in a new window

Popular airlines from Missoula Intl. Airport (MSO) to Chicago O'Hare Intl. Airport (ORD)

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Cheap Flights from Missoula to Chicago (MSO-ORD)

Prices were available within the past 7 days and start at $105 for one-way flights and $191 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Sep 11 - Sun, Sep 14
MSO
Missoula
ORD
Chicago
$191 Roundtrip, found 10 hours ago
$191
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Thu, Sep 11 from Missoula to Chicago, returning Sun, Sep 14, priced at $191 found 10 hours ago
American Airlines
Wed, Sep 10 - Mon, Sep 15
MSO
Missoula
ORD
Chicago
$201 Roundtrip, found 6 hours ago
$201
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Wed, Sep 10 from Missoula to Chicago, returning Mon, Sep 15, priced at $201 found 6 hours ago
Alaska Airlines
Thu, Sep 11 - Wed, Sep 17
MSO
Missoula
ORD
Chicago
$210 Roundtrip, found 10 hours ago
$210
Roundtrip
found 10 hours ago
Select Alaska Airlines flight, departing Thu, Sep 11 from Missoula to Chicago, returning Wed, Sep 17, priced at $210 found 10 hours ago
Hawaiian Airlines
Tue, Sep 9 - Tue, Sep 16
MSO
Missoula
ORD
Chicago
$210 Roundtrip, found 6 hours ago
$210
Roundtrip
found 6 hours ago
Select Hawaiian Airlines flight, departing Tue, Sep 9 from Missoula to Chicago, returning Tue, Sep 16, priced at $210 found 6 hours ago
United
Wed, Sep 10 - Mon, Sep 15
MSO
Missoula
ORD
Chicago
$211 Roundtrip, found 6 hours ago
$211
Roundtrip
found 6 hours ago
Select United flight, departing Wed, Sep 10 from Missoula to Chicago, returning Mon, Sep 15, priced at $211 found 6 hours ago
Alaska Airlines
Wed, Sep 10 - Mon, Sep 15
MSO
Missoula
ORD
Chicago
$224 Roundtrip, found 6 hours ago
$224
Roundtrip
found 6 hours ago
Select Alaska Airlines flight, departing Wed, Sep 10 from Missoula to Chicago, returning Mon, Sep 15, priced at $224 found 6 hours ago
American Airlines
Wed, Sep 24 - Mon, Sep 29
MSO
Missoula
ORD
Chicago
$225 Roundtrip, found 4 days ago
$225
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Sep 24 from Missoula to Chicago, returning Mon, Sep 29, priced at $225 found 4 days ago
Alaska Airlines
Thu, Sep 11 - Wed, Sep 17
MSO
Missoula
ORD
Chicago
$225 Roundtrip, found 1 day ago
$225
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Thu, Sep 11 from Missoula to Chicago, returning Wed, Sep 17, priced at $225 found 1 day ago
United
Thu, Sep 11 - Mon, Sep 15
MSO
Missoula
ORD
Chicago
$227 Roundtrip, found 2 days ago
$227
Roundtrip
found 2 days ago
Select United flight, departing Thu, Sep 11 from Missoula to Chicago, returning Mon, Sep 15, priced at $227 found 2 days ago
Delta
Fri, Sep 19 - Wed, Sep 24
MSO
Missoula
ORD
Chicago
$239 Roundtrip, found 5 days ago
$239
Roundtrip
found 5 days ago
Select Delta flight, departing Fri, Sep 19 from Missoula to Chicago, returning Wed, Sep 24, priced at $239 found 5 days ago

Find the cheapest month to fly from Missoula (MSO) to Chicago (ORD)

October is typically the cheapest month to fly

From $188 - $415 per traveler.

Graph displaying average flight prices per month

Alternative airports near Chicago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Midway Intl. MDW. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $374
MDW
Midway Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $374
Flights from Missoula (MSO) to Chicago (ORD)
Origin airport
Missoula Intl.
Destination airport
O'Hare Intl.
Airlines serving
Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, United
Roundtrip price
$191
Distance
1328 mi
Average flight time
4 hours 59 mins

Missoula to Chicago Flights

The cheapest times to fly from Missoula to Chicago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Missoula to Chicago are during the month of September. You can find some of the cheapest flights from Missoula to Chicago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Missoula to Chicago

Sunday is one of the best days to book for cheap flights from Missoula to Chicago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Missoula to Chicago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Missoula to Chicago in 2025. You can also book with separate airlines for your outbound and return journeys, from $105 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Missoula to Chicago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Missoula to Chicago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD) cost?
You'll find affordable return tickets from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD) starting at $191. Grab your seat and be on your way. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a American Airlines flight leaving MSO on August 7 2025 and touching down at ORD. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from MSO to ORD?
The cheapest flights from MSO to ORD are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from MSO to ORD?
With prices as low as $112 for a one-way journey from MSO to ORD, American Airlines is currently the cheapest airline on this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from MSO on August 26 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD)?
There are no daily direct flights available from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds before you know it.
What day of the week has the most flights from MSO to ORD?
You'll usually find Tuesday the quietest day for flights, while Fridays tend to be the busiest.* However this can change from season to season and during public holidays or peak travel times.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD)?
Select a flight from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD) that takes off before 3 PM to reduce the likelihood of delays. Departures after this time have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD) last-minute?
Holding off until just before your trip to book a ticket from MSO to ORD generally means paying more. While you may come across some last-minute offers, they're not always guaranteed. Be flexible with your itinerary to maximize your chances of landing a bargain.
Is it cheaper to book a MSO to ORD flight and hotel package?
Securing a MSO to ORD flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels in one place. Select from our extensive range of accommodations and then add car rentals, flights and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Missoula Intl. Airport (MSO) to O'Hare Intl. Airport (ORD)?
Generally, it's possible to cancel or reschedule your MSO to ORD flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and if any costs are involved. You'll also find more information on our Customer Service portal.

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