Top 10 Hotels in Midtown

See all 464 Hotels in Midtown
Club Quarters Hotel in Houston
Club Quarters Hotel in Houston

720 Fannin Street, Houston 77002

4.0 out of 5.0

Club Quarters Hotel in Houston is a full-service hotel designed for business travelers, in downtown Houston. A short walk fro …

$76
Hotel Derek Houston Galleria
Hotel Derek Houston Galleria

2525 West Loop S, Houston 77027

4.0 out of 5.0

Hotel Derek keeps you "In the Loop" with its prominent 610 Westheimer location, with hundreds of shops, dining and …

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Royal Sonesta Houston Galleria
Royal Sonesta Houston Galleria

2222 West Loop South, Houston 77027

4.0 out of 5.0

Located in Galleria, this hotel is within a 15-minute walk of Uptown Plaza and The Galleria. Memorial Park is 2.5 mi (4.1 km) …

$109
Best Western Plus Downtown Inn & Suites
Best Western Plus Downtown Inn & Suites

915 W Dallas St, Houston 77019

2.5 out of 5.0

Located in Downtown Houston, this hotel is within 1 mi (2 km) of Houston Public Library, Downtown Aquarium, and Toyota Center …

$120
Hotel ZaZa Houston
Hotel ZaZa Houston

5701 Main Street, Houston 77005

4.0 out of 5.0

This Houston boutique hotel lies in the Arts District within walking distance of numerous museums; the Texas Medical Center …

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Residence Inn by Marriott Houston West/Beltway 8 at Clay Rd.
Residence Inn by Marriott Houston West/Beltway 8 at Clay Rd.

10421 Clay Road, Houston 77041

3.0 out of 5.0
5 out of 5 (1 reviews)

Situated in Houston, this hotel is within 6 mi (10 km) of Memorial City Mall, Bear Creek Pioneers Park, and Town and Countr …

$84
The Sam Houston, Curio Collection by Hilton
The Sam Houston, Curio Collection by Hilton

1117 Prairie St, Houston 77002

4.0 out of 5.0

2 blocks from light rail, this Houston hotel occupies a historic downtown building 3 blocks from Minute Maid Park, 6 blocks …

$110
Aloft Houston by the Galleria
Aloft Houston by the Galleria

5415 Westheimer Road, Houston 77056

3.5 out of 5.0

Located in Galleria, this hotel is within 1 mi (2 km) of Williams Tower and The Galleria. Gerald D. Hines Waterwall Park an …

$85
Four Seasons Hotel Houston
Four Seasons Hotel Houston

1300 Lamar St, Houston 77010

5.0 out of 5.0

Four Seasons Hotel Houston is in the city center, a half-hour drive from the airport yet with easy access to the tranquil …

$269
Omni Houston Hotel
Omni Houston Hotel

4 Riverway, Houston 77056

4.5 out of 5.0

Set on secluded grounds just off Interstate 610, this modern high-rise is a mile from the upscale Galleria Mall and 0.5 miles …

$119

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Where to stay in Midtown

Midtown Hotel Guide

Houston is an important city in United States of America. It offers a range of quite interesting neighborhoods to explore, including Midtown, which is about 1 mile to the southwest of downtown Houston.

Houston is particularly well-known for its Johnson Space Center - NASA, as well as the Houston Zoo and The Galleria.

While in Midtown, consider visiting the Downtown Aquarium and Menil Collection, some of Midtown's most well-known places to check out.

There are plenty of Midtown hotels within walking distance from the Houston Natural Science Museum, including the Houston Marriott Medical Center, Lexington Hotel Houston Medical Center, Hilton Houston Plaza / Medical Center, Wyndham Houston - Medical Center Hotel and Suites and Residence Inn by Marriott Houston Medical Center/NRG Park.

The Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr and Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd are all situated just a short walk away from the Houston Children's Museum, and the Hotel ICON Autograph Collection and The Westin Houston Downtown can be found nearer to the House of Blues Houston.

Hoping to book a room near Midtown? There are hotels in the nearby Houston areas of Texas Medical Center and Greenway Plaza. In Texas Medical Center, check out the amenities and rates at the Hotel ZaZa Houston. The DoubleTree by Hilton Hotel Houston - Greenway Plaza in Greenway Plaza is another great choice.

Here at Expedia, our mission is to help you and your family get the most from your Houston experience. Visit our Houston vacation travel guide and Houston hotels page to discover more about this destination.