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Featured San Francisco Independent Hotels

See all 484 Hotels in San Francisco
San Francisco Marriott Union Square

San Francisco Marriott Union Square

480 Sutter Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (764 reviews)
Good hotel for the price. Clean and staff are friendly. - 

$209

$209
Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco
3.5 out of 5.0
3.9 out of 5 (1,580 reviews)
Not bad The hotel staff was very friendly and polite. The room was okay. It was clean but felt old and ther … - 

$199

$199
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

1550 Bayshore Hwy, Burlingame
3.0 out of 5.0
4.5 out of 5 (2,120 reviews)
Very clean, nice comfortable room, great staff, excellent manager, good variety at breakfast, great … - 

$143

$143
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,533 reviews)
Extremely friendly staff and love the atrium. Exceptionally nice place to stay in the hear of San Fran. - 

$235

$235
Hotel Whitcomb

Hotel Whitcomb

1231 Market St, San Francisco
3.5 out of 5.0
3.1 out of 5 (3,181 reviews)
Pretty, historic hotel in the civic center area Walking distance to nice restaurants and coffee nearby, and using lyft to get around is easy and ch … - 

$189

$189
Hotel Union Square

Hotel Union Square

114 Powell St, San Francisco
3.5 out of 5.0
3.7 out of 5 (791 reviews)
Central location Great location for exploring San Francisco but the downside is the noise at the weekend. If someone … - 

$218

$218
The Tuscan, A Noble House Hotel

The Tuscan, A Noble House Hotel

425 North Point, San Francisco
4.0 out of 5.0
4.2 out of 5 (2,352 reviews)
Staff was very polite and receptive. Gave us each a glass of wine at registration and a bag of popc … - 

$203

$203
Hyatt Regency San Francisco

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,290 reviews)
Great hotel, great location, does not include breakfast and fruits in the gym, but aside that all w … - 

$229

$229
Hotel Focus SFO

Hotel Focus SFO

111 Mitchell Ave, South San Francisco
2.0 out of 5.0
3.2 out of 5 (62 reviews)
Nice hotel handy to SOF and very convenient Convenient, had everything we required. Shuttles to the airport, not too far to a major shopping ce … - 

$129

$129
Red Roof PLUS+ San Francisco Airport

Red Roof PLUS+ San Francisco Airport

777 Airport Blvd, Burlingame
3.0 out of 5.0
3.4 out of 5 (1,008 reviews)
ccomfort, even though we checked out we were still able to use the airport shuttle pool and shower … - 

$121

$121
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,610 reviews)
Always a pleasant stay We've stayed here 3 times over the past couple of years. It's a great location with convenient park … - 

$208

$208
Pier 2620 Hotel Fisherman's Wharf

Pier 2620 Hotel Fisherman's Wharf

2620 Jones Street, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,904 reviews)
Great hotel in a great location. Easily accessible to everything. - 

$220

$220
Hotel Zephyr

Hotel Zephyr

250 Beach Street, San Francisco
3.5 out of 5.0
4.1 out of 5 (872 reviews)
I love this hotel. Will come back and stay here every time I come to San fransico - 

$237

$237
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,050 reviews)
Although we had to pay top dollar due to high occupancy, our room was wonderful ! - 

$280

$280
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.4 out of 5 (1,641 reviews)
Nice Stay, Decent Service Too long a wait to check in with so many staff working at 8 pm Sunday night. Place was not that bus … - 

$199

$199
Grand Hyatt San Francisco Union Square

Grand Hyatt San Francisco Union Square

345 Stockton St, San Francisco
4.0 out of 5.0
4.3 out of 5 (1,364 reviews)
Close to everything My SF experience was great. The only disappointment was we never were allowed to go up to the 36th … - 

$229

$229
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (2,751 reviews)
Nice view of the city Great staff and very helpful during check in process. - 

$194

$194
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,406 reviews)
Clean but service levels low. Requested extra towel and wine glasses for two days, never came. Over … - 

$161

$161
The Westin St Francis San Francisco on Union Square

The Westin St Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,808 reviews)
Good position for union square Avoid the queen bed room if possible very small room - 

$245

$245
Hyatt Regency San Francisco Airport

Hyatt Regency San Francisco Airport

1333 Bayshore Hwy, Burlingame
4.0 out of 5.0
4.0 out of 5 (1,264 reviews)
Ok Hotel but pricey!! This was an OK Hotel but it was on the Pricey side for value. The room was comfortable but small fo … - 

$179

$179
Map

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Independent San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in San Francisco, California. Known for well-appointed rooms and friendly, personalized service, each of the top Independent San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.