Find luxury hotels in Santa Croce, Venice

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Our top choices for Santa Croce luxury hotels

Papadopoli Hotel Venezia - MGallery Collection

4.0 star property
Santa Croce
9.2 out of 10, Wonderful, (1000)
"Not the most central of locations, but you can get a water taxi right to the hotel to go anywhere, and the room service is wonderful!"
United States
Mary
$180 nightly
The price is $205
Jan 7 - Jan 8, 2026
Total with taxes and fees
Papadopoli Hotel Venezia - MGallery Collection

Hotel Antiche Figure

3.0 star property
Santa Croce
9.8 out of 10, Exceptional, (1002)
"Staff were excellent, we loved the location. "
Canada
Barry
$119 nightly
The price is $140
Dec 16 - Dec 17
Total with taxes and fees
Hotel Antiche Figure

Hotel Canal Grande

4.0 star property
Santa Croce
9.6 out of 10, Exceptional, (1003)
"Room was amazing and the staff was extremely helpful "
United States
Tori
$133 nightly
The price is $157
Dec 24 - Dec 25
Total with taxes and fees
Hotel Canal Grande

Ca' Nigra Lagoon Resort

4.0 star property
Santa Croce
9.2 out of 10, Wonderful, (366)
"Great facility, staff extremely friendly and nice"
United States
Jorge
$161 nightly
The price is $185
Jan 8 - Jan 9, 2026
Total with taxes and fees
Ca' Nigra Lagoon Resort

Hotel San Cassiano Ca'Favretto

4.0 star property
Venice City Center
8.8 out of 10, Excellent, (1002)
"Outstanding staff, breakfast, location & view."
United States
Nissim
$87 nightly
The price is $106
Dec 14 - Dec 15
Total with taxes and fees
Hotel San Cassiano Ca'Favretto

Hotel Olimpia Venice, BW Signature Collection

3.5 star property
Santa Croce
9.6 out of 10, Exceptional, (1000)
"Amazing rooms, staff and breakfast! Highly recommend and definitely will return!"
United States
Ruby
$107 nightly
The price is $126
Dec 14 - Dec 15
Total with taxes and fees
Hotel Olimpia Venice, BW Signature Collection

Hotel Al Duca Di Venezia

3.0 star property
Venice City Center
9.2 out of 10, Wonderful, (1002)
"Our stay was amazing, we stayed one night but it’s a really good hotel to stay in Venice.The breakfast was wonderful "
United States
Ariadna
$94 nightly
The price is $112
Dec 11 - Dec 12
Total with taxes and fees
Hotel Al Duca Di Venezia

Hotel Palazzo Giovanelli e Gran Canal

4.0 star property
Venice City Center
8.6 out of 10, Excellent, (349)
"Lovely hotel with great staff. Location away from the crowd but easy links to centre"
United Kingdom
john
Hotel Palazzo Giovanelli e Gran Canal

Casa Caburlotto

Santa Croce
8.4 out of 10, Very Good, (590)
"Nice quiet place, breakfast good enough for everyone. For sure we will be come back."
Netherlands
Paulina
Casa Caburlotto

Santa Chiara Hotel

4.5 star property
Santa Croce
9.4 out of 10, Exceptional, (318)
"Conveniently located next to the main bus terminal and a good launching point to the city. The staff was super kind and helpful. "
United States
Jeremy
$212 nightly
The price is $244
Dec 16 - Dec 17
Total with taxes and fees
Santa Chiara Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Price trends for hotels in Santa Croce

Less expensive
More expensive
This month
Next month
November
May
$180
$179
Month
Price
January
$179
February
$186
March
$186
April
$257
May
$287
June
$276
July
$254
August
$227
September
$277
October
$276
November
$173
December
$180
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Santa Croce. Select dates and complete search for nightly totals inclusive of taxes and fees.

Find out more about Santa Croce

Santa Croceand its attractions for luxury travelers

For travelers seeking luxury in Florence's Santa Croce neighborhood, the area offers a captivating blend of history, culture, and refined experiences. Begin your journey at the stunning Basilica di Santa Croce, where you can admire the beautiful frescoes and the tombs of renowned figures like Michelangelo and Galileo, all while enjoying a private guided tour that delves into its rich history. Just a short stroll away, the leather market presents an opportunity to indulge in exquisite handcrafted goods, perfect for those looking to take home a piece of Italian craftsmanship. For art lovers, the Museo dell'Opera di Santa Croce showcases masterpieces in a less crowded setting, allowing for an intimate experience with works by Giotto and Donatello. Dining in Santa Croce is a treat, with Michelin-starred restaurants like Enoteca Pinchiorri, where you can savor innovative Tuscan cuisine paired with fine wines in an elegant setting. After a day of exploration, unwind at luxurious hotels like Hotel Brunelleschi, where you can enjoy spacious, elegant rooms, a rooftop terrace with breathtaking views of Florence, and impeccable service that caters to your every need. Here, the blend of modern comfort and historical charm creates an unforgettable retreat.

Find the best luxury hotels and resorts in Santa Croce

For travelers seeking a luxurious escape in Santa Croce, Venice, these hotels provide exquisite amenities and unparalleled service to ensure a memorable stay.

Santa Croce Boutique Hotel

  • Why it's great for a luxury retreat: Santa Croce Boutique Hotel stands out with a perfect guest review rating of 10.0, making it a premier choice for luxury travelers. This stylish boutique hotel features artisanal elements, premium bedding, and personalized concierge services to cater to every guest's desires. The addition of champagne service adds a celebratory touch to any stay, ensuring guests feel truly pampered.
  • Other amenities: This hotel boasts an onsite art gallery and designer stores for a unique shopping experience. Guests can enjoy winery private tours and release events, adding an exclusive touch to their Venetian adventure. Additional features include a steam room, daily housekeeping, and a charming garden area, all contributing to a luxurious and relaxing stay.
  • Neighborhood: Santa Croce
  • Nearby attractions: Port of Venice - 6.55 miles, Tronchetto Waterbus Stop - 6.57 miles, Porto Marghera - 5.36 miles

Hotel Canal Grande

  • Why it's great for a luxury retreat: Hotel Canal Grande is the epitome of luxury in Venice, a remarkable guest review rating of 9.6. This elegant hotel offers premium bedding, plush bathrobes, and 24-hour room service, ensuring guests enjoy the utmost comfort and convenience during their stay. The concierge service is available to cater to all guests' needs, from arranging transportation to recommending local attractions, making it an ideal choice for travelers.
  • Other amenities: Guests can unwind on the terrace or in the beautiful yard, while additional services such as airport transportation and early check-in enhance the overall experience. The hotel’s historical district location adds to its charm, allowing travelers to explore nearby museums and cultural sites easily. With housekeeping available daily, complimentary toiletries, and options for nearby winery tours, Hotel Canal Grande offers a truly indulgent Venetian experience.
  • Neighborhood: Santa Croce
  • Nearby attractions: Port of Venice - 6.55 miles, Tronchetto Waterbus Stop - 6.57 miles, Porto Marghera - 5.84 miles

Hotel Olimpia Venice, BW Signature Collection

  • Why it's great for a luxury retreat: Hotel Olimpia Venice is an inviting retreat for luxury seekers, featuring a strong guest review rating of 9.4. This hotel provides a concierge service to assist guests with personalized recommendations and arrangements, ensuring a seamless visit. Its stylish ambiance and comfortable amenities make it a delightful choice for travelers looking to immerse themselves in Venice’s rich culture.
  • Other amenities: Guests can enjoy daily housekeeping, a serene terrace, and complimentary toiletries. The hotel offers convenient airport shuttle services and transportation options, making arrivals and departures straightforward. With a traditional hotel design that echoes Venice's historical charm, along with a relaxing garden area, Hotel Olimpia balances elegance with comfort for a perfect stay.
  • Neighborhood: Santa Croce
  • Nearby attractions: Piazzale Roma - 0.24 miles, Grand Canal - 0.24 miles, Port of Venice - 0.67 miles

Palazzo Odoni

  • Why it's great for a luxury retreat: Palazzo Odoni offers an exquisite luxury experience in Venice, earning an excellent guest review rating of 9.4. Guests are treated to premium bedding and plush bathrobes, ensuring comfort during their stay. The 24-hour room service and attentive concierge provide personalized service that enhances the overall experience for travelers.
  • Other amenities: Guests can enjoy complimentary buffet breakfast and daily housekeeping services. The hotel provides convenient airport transportation and shuttle services, making it easy for guests to navigate their travels. Guests can explore the nearby museum locations, and the hotel offers a snack bar for light refreshments throughout the day. With options for free cribs and a relaxed atmosphere, Palazzo Odoni combines elegance with thoughtful amenities.
  • Neighborhood: Santa Croce
  • Nearby attractions: Piazzale Roma - 0.13 miles, Grand Canal - 0.13 miles, Port of Venice - 0.57 miles

Papadopoli Hotel Venezia - MGallery Collection

  • Why it's great for a luxury retreat: With a stellar guest review rating of 9.2, Papadopoli Hotel Venezia represents the essence of luxury in Venice. The hotel features premium bedding, soft bathrobes, and 24-hour room service, providing guests with an indulgent experience. The attentive concierge service is ready to assist with any needs, ensuring a personalized touch throughout your stay.
  • Other amenities: Guests can enjoy the lovely terrace and free cribs for families traveling with infants. The hotel is located in a historical district, making it easy to explore local attractions. Additional offerings include self-parking, housekeeping services, and the option for late check-out, providing convenience alongside luxury. This hotel also features balconies and furnished patios, enhancing the experience of relaxation within the serene Venetian atmosphere.
  • Neighborhood: Santa Croce
  • Nearby attractions: Piazzale Roma - 0.13 miles, Grand Canal - 0.13 miles, Port of Venice - 0.56 miles

Top Santa Croce Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Santa Croce?
Known for its museums and cathedral, Santa Croce also has some interesting things to see and do including Piazzale Roma, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Santa Croce?
Santa Chiara Hotel is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Santa Croce Boutique Hotel and Papadopoli Hotel Venezia - MGallery Collection are other upscale choices for your stay.
What's there to see and do in Santa Croce?
Enjoy Santa Croce with a stop at Piazzale Roma, Grand Canal, and Venetian Museum of Natural History. If you have a little extra time during your trip, you might want to check out Fondaco dei Turchi and Ca'Pesaro.

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