A narrow canal flanked by historic buildings with arched windows and balconies.

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Our top choices for Santa Croce luxury hotels

Palazzo Venart Luxury Hotel

Palazzo Venart Luxury Hotel
5.0 star property
Venice City Center
9.8 out of 10, Exceptional, (184 reviews)
  • cleanliness
    Michelin-starred cuisine and bespoke service at a historic palazzo near Rialto Bridge and St. Mark's Square.
$619 nightly
The price is $692
Aug 5 - Aug 6
Total with taxes and fees
Palazzo Venart Luxury Hotel

Santa Chiara Hotel

Santa Chiara Hotel
4.5 star property
Santa Croce
9.4 out of 10, Exceptional, (369 reviews)
  • cleanliness
    Waterfront luxury graces this Venice hotel with its pillow-top beds and rooftop terrace overlooking the Grand Canal.
$260 nightly
The price is $297
Jul 26 - Jul 27
Total with taxes and fees
Santa Chiara Hotel

Hotel Palazzo Giovanelli e Gran Canal

Hotel Palazzo Giovanelli e Gran Canal
4.0 star property
Venice City Center
8.6 out of 10, Excellent, (349 reviews)
$448 nightly
The price is $503
Aug 6 - Aug 7
Total with taxes and fees
Hotel Palazzo Giovanelli e Gran Canal

Papadopoli Hotel Venezia - MGallery Collection

Papadopoli Hotel Venezia - MGallery Collection
4.0 star property
Santa Croce
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Elegant Venetian retreat with a living plant wall and designer touches near Piazzale Roma.
$259 nightly
The price is $296
Aug 16 - Aug 17
Total with taxes and fees
Papadopoli Hotel Venezia - MGallery Collection

Hotel Canal Grande

Hotel Canal Grande
4.0 star property
Santa Croce
9.6 out of 10, Exceptional, (1,005 reviews)
$207 nightly
The price is $238
Jul 26 - Jul 27
Total with taxes and fees
Hotel Canal Grande

Hotel Aquarius Venice

Hotel Aquarius Venice
4.0 star property
Venice City Center
9.6 out of 10, Exceptional, (462 reviews)
$178 nightly
The price is $206
Aug 21 - Aug 22
Total with taxes and fees
Hotel Aquarius Venice

Ca' Nigra Lagoon Resort

Ca' Nigra Lagoon Resort
4.0 star property
Santa Croce
9.2 out of 10, Wonderful, (397 reviews)
$148 nightly
The price is $173
Jul 22 - Jul 23
Total with taxes and fees
Ca' Nigra Lagoon Resort

Santa Croce Boutique Hotel

Santa Croce Boutique Hotel
4.5 star property
Santa Croce
10.0 out of 10, Exceptional, (518 reviews)
  • cleanliness
    Venetian elegance unfolds at this luxury hotel with a boutique feel, steam room, and garden sanctuary.
$167 nightly
The price is $194
Aug 2 - Aug 3
Total with taxes and fees
Santa Croce Boutique Hotel

Hotel Carlton on the Grand Canal

Hotel Carlton on the Grand Canal
4.0 star property
Santa Croce
8.4 out of 10, Very Good, (1,005 reviews)
$137 nightly
The price is $160
Jul 26 - Jul 27
Total with taxes and fees
Hotel Carlton on the Grand Canal

Hotel Ca' Zusto Venezia

Hotel Ca' Zusto Venezia
4.0 star property
Santa Croce
9.2 out of 10, Wonderful, (1,001 reviews)
$165 nightly
The price is $192
Aug 18 - Aug 19
Total with taxes and fees
Hotel Ca' Zusto Venezia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Price trends for hotels in Santa Croce

Less expensive
More expensive
Next month
February
May
$220
Month
Price
January
$220
February
$177
March
$199
April
$279
May
$346
June
$258
July
$246
August
$220
September
$295
October
$271
November
$195
December
$186
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Santa Croce. Select dates and complete search for nightly totals inclusive of taxes and fees.

Find out more about Santa Croce

Santa Croceand its attractions for luxury travelers

For travelers seeking luxury in Florence's Santa Croce neighborhood, the area offers a captivating blend of history, culture, and refined experiences. Begin your journey at the stunning Basilica di Santa Croce, where you can admire the beautiful frescoes and the tombs of renowned figures like Michelangelo and Galileo, all while enjoying a private guided tour that delves into its rich history. Just a short stroll away, the leather market presents an opportunity to indulge in exquisite handcrafted goods, perfect for those looking to take home a piece of Italian craftsmanship. For art lovers, the Museo dell'Opera di Santa Croce showcases masterpieces in a less crowded setting, allowing for an intimate experience with works by Giotto and Donatello. Dining in Santa Croce is a treat, with Michelin-starred restaurants like Enoteca Pinchiorri, where you can savor innovative Tuscan cuisine paired with fine wines in an elegant setting. After a day of exploration, unwind at luxurious hotels like Hotel Brunelleschi, where you can enjoy spacious, elegant rooms, a rooftop terrace with breathtaking views of Florence, and impeccable service that caters to your every need. Here, the blend of modern comfort and historical charm creates an unforgettable retreat.

Find the best luxury hotels and resorts in Santa Croce

For travelers seeking a luxurious escape in Santa Croce, Venice, these hotels provide exquisite amenities and unparalleled service to ensure a memorable stay.

Santa Croce Boutique Hotel

  • Why it's great for a luxury retreat: Santa Croce Boutique Hotel stands out with a perfect guest review rating of 10.0, making it a premier choice for luxury travelers. This stylish boutique hotel features artisanal elements, premium bedding, and personalized concierge services to cater to every guest's desires. The addition of champagne service adds a celebratory touch to any stay, ensuring guests feel truly pampered.
  • Other amenities: This hotel boasts an onsite art gallery and designer stores for a unique shopping experience. Guests can enjoy winery private tours and release events, adding an exclusive touch to their Venetian adventure. Additional features include a steam room, daily housekeeping, and a charming garden area, all contributing to a luxurious and relaxing stay.
  • Neighborhood: Santa Croce
  • Nearby attractions: Port of Venice - 6.55 miles, Tronchetto Waterbus Stop - 6.57 miles, Porto Marghera - 5.36 miles

Hotel Canal Grande

  • Why it's great for a luxury retreat: Hotel Canal Grande is the epitome of luxury in Venice, a remarkable guest review rating of 9.6. This elegant hotel offers premium bedding, plush bathrobes, and 24-hour room service, ensuring guests enjoy the utmost comfort and convenience during their stay. The concierge service is available to cater to all guests' needs, from arranging transportation to recommending local attractions, making it an ideal choice for travelers.
  • Other amenities: Guests can unwind on the terrace or in the beautiful yard, while additional services such as airport transportation and early check-in enhance the overall experience. The hotel’s historical district location adds to its charm, allowing travelers to explore nearby museums and cultural sites easily. With housekeeping available daily, complimentary toiletries, and options for nearby winery tours, Hotel Canal Grande offers a truly indulgent Venetian experience.
  • Neighborhood: Santa Croce
  • Nearby attractions: Port of Venice - 6.55 miles, Tronchetto Waterbus Stop - 6.57 miles, Porto Marghera - 5.84 miles

Hotel Olimpia Venice, BW Signature Collection

  • Why it's great for a luxury retreat: Hotel Olimpia Venice is an inviting retreat for luxury seekers, featuring a strong guest review rating of 9.4. This hotel provides a concierge service to assist guests with personalized recommendations and arrangements, ensuring a seamless visit. Its stylish ambiance and comfortable amenities make it a delightful choice for travelers looking to immerse themselves in Venice’s rich culture.
  • Other amenities: Guests can enjoy daily housekeeping, a serene terrace, and complimentary toiletries. The hotel offers convenient airport shuttle services and transportation options, making arrivals and departures straightforward. With a traditional hotel design that echoes Venice's historical charm, along with a relaxing garden area, Hotel Olimpia balances elegance with comfort for a perfect stay.
  • Neighborhood: Santa Croce
  • Nearby attractions: Piazzale Roma - 0.24 miles, Grand Canal - 0.24 miles, Port of Venice - 0.67 miles

Palazzo Odoni

  • Why it's great for a luxury retreat: Palazzo Odoni offers an exquisite luxury experience in Venice, earning an excellent guest review rating of 9.4. Guests are treated to premium bedding and plush bathrobes, ensuring comfort during their stay. The 24-hour room service and attentive concierge provide personalized service that enhances the overall experience for travelers.
  • Other amenities: Guests can enjoy complimentary buffet breakfast and daily housekeeping services. The hotel provides convenient airport transportation and shuttle services, making it easy for guests to navigate their travels. Guests can explore the nearby museum locations, and the hotel offers a snack bar for light refreshments throughout the day. With options for free cribs and a relaxed atmosphere, Palazzo Odoni combines elegance with thoughtful amenities.
  • Neighborhood: Santa Croce
  • Nearby attractions: Piazzale Roma - 0.13 miles, Grand Canal - 0.13 miles, Port of Venice - 0.57 miles

Papadopoli Hotel Venezia - MGallery Collection

  • Why it's great for a luxury retreat: With a stellar guest review rating of 9.2, Papadopoli Hotel Venezia represents the essence of luxury in Venice. The hotel features premium bedding, soft bathrobes, and 24-hour room service, providing guests with an indulgent experience. The attentive concierge service is ready to assist with any needs, ensuring a personalized touch throughout your stay.
  • Other amenities: Guests can enjoy the lovely terrace and free cribs for families traveling with infants. The hotel is located in a historical district, making it easy to explore local attractions. Additional offerings include self-parking, housekeeping services, and the option for late check-out, providing convenience alongside luxury. This hotel also features balconies and furnished patios, enhancing the experience of relaxation within the serene Venetian atmosphere.
  • Neighborhood: Santa Croce
  • Nearby attractions: Piazzale Roma - 0.13 miles, Grand Canal - 0.13 miles, Port of Venice - 0.56 miles

Top Santa Croce Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in Santa Croce?
Travel to Marco Polo Airport (VCE) Airport or Treviso Airport (TSF) Airport, and then treat yourself to a stay at one of 6 Santa Croce luxury hotels. Known for its museums and cathedral, Santa Croce also has some interesting things to see and do including Piazzale Roma, so you may want to take in the local sights during your visit.
What's the best luxury accommodation in Santa Croce?
Santa Chiara Hotel is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Palazzo Venart Luxury Hotel and Santa Croce Boutique Hotel are other upscale choices for your stay.
How many luxury hotels will I find in Santa Croce?
Lie in the lap of luxury during your getaway to Santa Croce in one of Expedia's 6 luxury hotels.
What's there to see and do in Santa Croce?
Enjoy Santa Croce with a stop at Piazzale Roma, Ca' Pesaro Galleria Internazionale d'Arte Moderna, and Venetian Museum of Natural History. If you have a little extra time during your trip, you might want to check out San Stae and Tolentini.

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