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Compare 258 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Amet Nature Retreat

4.5 star property
10.0 out of 10, Exceptional, (2)
"The property is beautiful and the staff couldn't be any nicer. Room was very comfortable. Experiences seem a bit overpriced - you can do many things on your own with a 4WD and an adventurous spirit. "
$293 nightly
The price is $355
Aug 24 - Aug 25
Total with taxes and fees
Amet Nature Retreat

Buena Vista Oceanfront & Hot Springs Resort

3.5 star property
8.4 out of 10, Very Good, (283)
"Best in the Baja"
$86 nightly
The price is $111
Sep 4 - Sep 5
Total with taxes and fees
Buena Vista Oceanfront & Hot Springs Resort

Hotel Aeropuerto Los Cabos

3.5 star property
8.6 out of 10, Excellent, (1001)
"I like the proximity to the airport and the free shuttle ride. Breakfast was decent too. "
$129 nightly
The price is $159
Aug 24 - Aug 25
Total with taxes and fees
Hotel Aeropuerto Los Cabos

Cactus Inn Los Cabos

3.0 star property
8.4 out of 10, Very Good, (263)
"Great place for the price. "
$77 nightly
The price is $96
Sep 22 - Sep 23
Total with taxes and fees
Cactus Inn Los Cabos

Casa Pajaros

2.0 star property
$174 nightly
The price is $209
Aug 24 - Aug 25
Total with taxes and fees
Casa Pajaros

Hotel Punta Pescadero Paradise

3.5 star property
9.2 out of 10, Wonderful, (220)
"Very nice place "
$172 nightly
The price is $204
Sep 1 - Sep 2
Total with taxes and fees
Hotel Punta Pescadero Paradise

Hotel Palmas De Cortez

3.5 star property
8.2 out of 10, Very Good, (414)
"Pretty nice place. Clean rooms and great staff. Our stay was for fishing. There were other activities available too. Would come back. "
$188 nightly
The price is $231
Sep 22 - Sep 23
Total with taxes and fees
Hotel Palmas De Cortez

Playa del Sol

3.0 star property
8.8 out of 10, Excellent, (194)
"Great location for the Pickleball Tournament which was next door at Palmas Pickleball Resort. Loved our Poolside Room!"
$145 nightly
The price is $179
Aug 29 - Aug 30
Total with taxes and fees
Playa del Sol

SUITES LOMBOY & PLAZA

3.5 star property
9.4 out of 10, Exceptional, (93)
"Wonderful easy check in and the room is immaculate."
$92 nightly
The price is $114
Sep 22 - Sep 23
Total with taxes and fees
SUITES LOMBOY & PLAZA

Hotel Rancho Buena Vista

3.0 star property
6.4 out of 10, (54)
"Clean, quiet, efficient, staff good location. Firm bed good air conditioner big shower with lots of hot water. Nice pool ocean front good restaurant."
$122 nightly
The price is $149
Sep 1 - Sep 2
Total with taxes and fees
Hotel Rancho Buena Vista

Four Seasons Resort Los Cabos at Costa Palmas

5.0 star property
9.4 out of 10, Exceptional, (55)
"Amazing experience, facilities, beach and staff!!!"
$933 nightly
The price is $1,097
Sep 7 - Sep 8
Total with taxes and fees
Four Seasons Resort Los Cabos at Costa Palmas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santiago

Explore the historic mission town's colonial plaza where local artisans sell handcrafted leather goods and regional foods. Nearby Sierra de la Laguna Biosphere Reserve offers excellent hiking trails with guides who know where to spot endemic wildlife.

Santiago showing a church or cathedral

Stay near popular Santiago attractions

Tropic of Cancer Monument
Tropic of Cancer Monument featuring flowers

Tropic of Cancer Monument

4/5(7 reviews)

Full moon parties and artisanal markets bring this secluded plaza to life. Admire the modern work of art depicting the globe and marking a significant latitude.

Top Santiago Hotel Reviews

Frequently asked questions

What are the most romantic hotels in Santiago for couples?
For a truly enchanting experience, Amet Nature Retreat in Santiago, Mexico, offers a serene escape with a stellar rating of 4.5 stars. Nestled by a picturesque lake, this hotel provides couples with stunning lake views that create a romantic backdrop for any getaway. See all romantic hotels in Santiago.
When is the best time to go to Santiago?
The most popular time to visit Santiago is during the months of September and October, when the weather is pleasantly mild and the city comes alive with vibrant cultural events. Average temperatures during this period range from the mid-60s to low 70s Fahrenheit, making it ideal for exploring the city's diverse neighborhoods, enjoying outdoor markets, and soaking in the stunning views from San Cristóbal Hill.

As you navigate your travel plans, keep in mind that Santiago experiences its peak tourist season from December to February, when visitors flock to enjoy the summer sun. While this is a lively time to be in the city, with outdoor festivals and a bustling atmosphere, it can also mean larger crowds at major attractions. Booking accommodations and dining ahead of time can ensure that you receive the attentive service you desire during your stay.

For those who appreciate outdoor adventures, September and October offer the great climate for activities such as hiking in the nearby Andes mountains, visiting the beautiful vineyards in the surrounding regions, and enjoying leisurely strolls through the city's picturesque parks. The pleasant weather allows for a comfortable exploration experience, with many opportunities to engage with local culture and cuisine.

If you're looking for a more budget-friendly experience, consider visiting Santiago in late August. This month often sees lower prices for accommodations and attractions, allowing you to enjoy the city's offerings without the peak season crowds.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santiago hotel for you.
How can I save on a Santiago hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santiago hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santiago hotel?
Prices for hotels in Santiago often vary, but you can find a great deal from $96 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.