Title: The Best 5 Star Hotels in Cape Cod, MA from $153 | Expedia.com [Cape Cod Travel Guide](https://expedia.com/Cape-Cod.dx180061)[Hotels in Cape Cod](https://expedia.com/Cape-Cod-Hotels.d180061.Travel-Guide-Hotels)[Vacation Rentals in Cape Cod](https://expedia.com/Cape-Cod-Vacation-Rentals.d180061.Travel-Guide-VacationRentals)[Flights to Cape Cod](https://expedia.com/Cheap-Flights-To-Cape-Cod.d180061.Travel-Guide-Flights)[Things to do in Cape Cod](https://expedia.com/Things-To-Do-In-Cape-Cod.d180061.Travel-Guide-Activities)[Car Rentals in Cape Cod](https://expedia.com/Car-Rentals-In-Cape-Cod.d180061.Car-Rental-Guide)[Cape Cod Vacation Packages](https://expedia.com/Cape-Cod.d180061.Destination-Travel-Guides) ![Hyannis showing a marina and a bay or harbor](https://images.trvl-media.com/place/553248635146342095/727e0fd8-4e19-4ca2-997d-3604702ab1c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635146342095/727e0fd8-4e19-4ca2-997d-3604702ab1c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Cape Cod 5 Star Hotels Tonight [Feb 5 - Feb 6](https://www.expedia.com/Hotel-Search?regionId=180061&startDate=2026-02-05&endDate=2026-02-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=180061&startDate=2026-02-06&endDate=2026-02-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=180061&startDate=2026-02-06&endDate=2026-02-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=180061&startDate=2026-02-13&endDate=2026-02-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Cape Cod 5-star hotels ![Round Cove Suite | Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/ce420299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach bar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/9873e07e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/2c23c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room, 1 King Bed | Frette Italian sheets, premium bedding, down comforters, minibar](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/58f6c718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wequassett Resort and Golf Club [](https://www.expedia.com/Harwich-Hotels-Wequassett-Resort-And-Golf-Club.h3689.Hotel-Information) Harwich 9.4/10 Exceptional (244 reviews) "The staff is amazing, they are kind and always looking for ways to help and make you feel welcome." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karla $328 nightly $375 total Feb 19 - Feb 20 Total with taxes and fees [](https://www.expedia.com/Harwich-Hotels-Wequassett-Resort-And-Golf-Club.h3689.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Cape-Cod-Hotels.s50-0-d180061.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Cape-Cod-Hotels.s50-0-d180061.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Cape Cod. ![Margaritaville Resort Cape Cod](https://images.trvl-media.com/lodging/1000000/20000/12900/12897/b57e0b1f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Margaritaville Resort Cape Cod 1225 Iyannough Rd Hyannis MA $208 nightly $238 total Feb 10 - Feb 11 Total with taxes and fees 8.6/10 Excellent! (441 reviews) [](https://expedia.com/Hyannis-Hotels-Cape-Codder-Resort-And-Spa.h12897.Hotel-Information) ![Doubletree by Hilton Cape Cod - Hyannis](https://images.trvl-media.com/lodging/1000000/50000/40500/40461/9f940314_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Doubletree by Hilton Cape Cod - Hyannis 287 Iyannough Rd Hyannis MA $134 nightly $153 total Feb 22 - Feb 23 Total with taxes and fees 8.2/10 Very Good! (888 reviews) [](https://expedia.com/Hyannis-Hotels-Doubletree-By-Hilton-Cape-Cod-Hyannis.h40461.Hotel-Information) ![Brass Key Guesthouse - Adults Only](https://images.trvl-media.com/lodging/19000000/18640000/18632900/18632862/94673ecf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Brass Key Guesthouse - Adults Only 67 Bradford St Provincetown MA [Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=18632862&PinnedHotelID=18632862&HadPinnedHotel=true®ionId=180061) 9.6/10 Exceptional! (450 reviews) [](https://expedia.com/Provincetown-Hotels-Brass-Key-Guesthouse-Adults-Only.h18632862.Hotel-Information) Still don't see what you're looking for? [See all properties in Cape Cod.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=180061&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=180061&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=180061&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=180061&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=180061&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F6%2F2026&endDate=2%2F7%2F2026®ionId=180061&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Cape Cod Windswept beaches and charming seaside towns await along this hook-shaped peninsula. Bike the Cape Cod Rail Trail, explore Provincetown's art galleries, or take a whale-watching tour from Hyannis Harbor. [See all hotels in Cape Cod](https://www.expedia.com/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&adults=2®ionId=180061) ![Hyannis showing a marina and a bay or harbor](https://images.trvl-media.com/place/553248635146342095/727e0fd8-4e19-4ca2-997d-3604702ab1c6.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Cape Cod Hotel Reviews ![Wequassett Resort and Golf Club](https://images.trvl-media.com/lodging/1000000/10000/3700/3689/9873e07e_y.jpg) ### Wequassett Resort and Golf Club 10/10 Excellent "The staff is amazing, they are kind and always looking for ways to help and make you feel welcome." [](https://expedia.com/Harwich-Hotels-Wequassett-Resort-And-Golf-Club.h3689.Hotel-Information) ## Find out more about Cape Cod Ready for an incredible adventure? Add further pleasure on your next trip to Cape Cod by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Cape Cod so popular in the last year. There's no reason to delay a getaway to Cape Cod any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Cape Cod and indulge in the finer things in life for a while. What are you waiting for? ### Book the Best Cape Cod 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Excellent service, delicious meals, and attentive guest service are all waiting for you. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What creature comforts do you want in your lodging? A concierge to help you make reservations at that outstanding restaurant? A full-body massage to help your cares fall away? Comfortable beds, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. Yearning for experiences outside your hotel room? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Cape Cod are waiting for you to relax after an exciting day. ### Your Getaway Starts Today The results are in, and Cape Cod 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Choose one of our Cape Cod 5-star hotels today and settle down in complete comfort tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Cape Cod? > - Search for the lowest price per night from $153 ### What makes a hotel 5 stars in Cape Cod? ### Are there any 5-star all-inclusive resorts in Cape Cod? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Dennis Pond Conservation Area ](https://www.expedia.com/Dennis-Pond-Conservation-Area-Hotels.0-l6297906-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Yarmouth Port ](https://www.expedia.com/4Star-Yarmouth-Port-Hotels.s40-0-d183353.Travel-Guide-Filter-Hotels) - [Hyannis Hotels ](https://www.expedia.com/Hyannis-Hotels.d1544.Travel-Guide-Hotels) - [Hotels near Bayberry Hills Golf Course ](https://www.expedia.com/Bayberry-Hills-Golf-Course-Hotels.0-l6182773-0.Travel-Guide-Filter-Hotels) - [Yarmouth Port Hotels ](https://www.expedia.com/Yarmouth-Port-Hotels.d183353.Travel-Guide-Hotels) - 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[Dennis Pond Conservation Area ](https://www.expedia.com/Dennis-Pond-Conservation-Area-Yarmouth-Port.d6297906.Vacation-Attraction) - [Bayberry Hills Golf Course ](https://www.expedia.com/Bayberry-Hills-Golf-Course-West-Yarmouth.d6182773.Vacation-Attraction) - [Visit Yarmouth Port ](https://www.expedia.com/Yarmouth-Port.dx183353) - [Visit Cummaquid ](https://www.expedia.com/Cummaquid.dx3000441001) - [Winslow Crocker House ](https://www.expedia.com/Winslow-Crocker-House-Yarmouth-Port.d553248621532666541.Vacation-Attraction) - [Long Pasture Wildlife Sanctuary ](https://www.expedia.com/Long-Pasture-Wildlife-Sanctuary-Barnstable.d6287372.Vacation-Attraction) - [Captain Bangs Hallet House Museum ](https://www.expedia.com/Captain-Bangs-Hallet-House-Museum-Yarmouth-Port.d6287119.Vacation-Attraction) - [Wild Animal Lagoon ](https://www.expedia.com/Wild-Animal-Lagoon-West-Yarmouth.d6286727.Vacation-Attraction) - [Edward Gorey House ](https://www.expedia.com/Edward-Gorey-House-Yarmouth-Port.d6286501.Vacation-Attraction) - 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