A marina with various boats docked, surrounded by houses and a pier extending into the water.

Find 5 Star Hotels in Cape Cod, MA from $156

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Check availability on Cape Cod 5 Star Hotels

Tonight
Sep 23 - Sep 24
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Sep 24 - Sep 25
This weekend
Sep 25 - Sep 27
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Oct 2 - Oct 4

Our top choices for Cape Cod 5-star hotels

A balcony with wicker furniture, a table with a vase and wine glass, and a view of the sea.
A pool area with lounge chairs and a fire pit, surrounded by stone walls and potted plants.
A sunlit room with a view of the sea, featuring a sofa, a round table, and a chair.
A room with a view of the sea, featuring a sofa, two chairs, a small table with a vase and a bottle, and a patterned carpet.

1. Wequassett Resort and Golf Club

Wequassett Resort and Golf Club
Harwich
United States
Angela
$442 nightly
$505 total
Oct 19 - Oct 20
Total with taxes and fees
Wequassett Resort and Golf Club
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Cape Cod.
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

1225 Iyannough Rd Hyannis MA
$207 nightly
$237 total
Oct 12 - Oct 13
Total with taxes and fees
8.6/10 Excellent! (775 reviews)
Margaritaville Resort Cape Cod
Uncommoner Hotel by Reverie Boutique Collection

Uncommoner Hotel by Reverie Boutique Collection

135 Route 28 West Yarmouth MA
$137 nightly
$156 total
Oct 13 - Oct 14
Total with taxes and fees
9.2/10 Wonderful! (346 reviews)
Uncommoner Hotel by Reverie Boutique Collection
Crowne Pointe Historic Inn & Spa - Adults Only

Crowne Pointe Historic Inn & Spa - Adults Only

82 Bradford Street Provincetown MA
$307 nightly
$351 total
Sep 27 - Sep 28
Total with taxes and fees
9.2/10 Wonderful! (938 reviews)
Crowne Pointe Historic Inn & Spa - Adults Only
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Cape Cod

Windswept beaches and charming seaside towns await along this hook-shaped peninsula. Bike the Cape Cod Rail Trail, explore Provincetown's art galleries, or take a whale-watching tour from Hyannis Harbor.

See all hotels in Cape Cod
A marina with various boats docked, a wooden pier, and houses in the background.

Top Cape Cod Hotel Reviews

Find out more about Cape Cod

Ready for an incredible adventure? Add further pleasure on your next trip to Cape Cod by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Cape Cod so popular in the last year. There's no reason to delay a getaway to Cape Cod any longer. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Reserve one of our 5-star hotels in Cape Cod and indulge in the finer things in life for a while. What are you waiting for?

Book the Best Cape Cod 5-Star Hotels

You'll have a wonderful time at one of these 5-star hotels. Excellent service, delicious meals, and attentive guest service are all waiting for you. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What creature comforts do you want in your lodging? A concierge to help you make reservations at that outstanding restaurant? A full-body massage to help your cares fall away? Comfortable beds, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.

Yearning for experiences outside your hotel room? We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Cape Cod are waiting for you to relax after an exciting day.

Your Getaway Starts Today

The results are in, and Cape Cod 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Choose one of our Cape Cod 5-star hotels today and settle down in complete comfort tomorrow.

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Cape Cod?
How much you pay for a 5-star hotel in Cape Cod depends on factors such as when you plan to go and the length of your trip. An insider tip for landing the best deal? Use our pricing filters to compare the available options for your chosen dates.
  • Search for the lowest price per night from $156
What makes a hotel 5 stars in Cape Cod?
Exemplary guest service is integral to every 5-star hotel in Cape Cod. From the minute you step through the door, staff ensure your every need is met, whether answering room service calls 24/7 or providing a turn-down service. In addition, hotels must offer upscale amenities to be entitled to a 5-star rating. These can include deluxe baths, saunas or spas, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Cape Cod?
Our handy filters are the quickest way to narrow down what you want. Select "All inclusive" and "5-star" to see the most upscale resorts in Cape Cod where your meals, lodging, activities and entertainment are included in the upfront price. At these escapes, your vacation is pure relaxation and indulgence from the moment you enter the lobby.

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