Find all hotels by Independent in Charleston, MO from $61
Check prices for these dates
Compare rooms and suites by Independent in Charleston with rates, reviews, and availability. Most hotels are fully refundable.
The Riverview
Cape Girardeau
9.4 out of 10, Exceptional, (466)
"Place was nice and safe"
ryan
$96 nightly
The price is $109
Dec 9 - Dec 10
Total with taxes and fees
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Sikeston
8.4 out of 10, Very Good, (716)
"Stayed one night. Good rate for the Hotel "
Paul
$53 nightly
The price is $61
Jan 8 - Jan 9, 2026
Total with taxes and fees
Town House Inn Cape Giradreau
Cape Girardeau
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
Gary
$57 nightly
The price is $64
Jan 4 - Jan 5, 2026
Total with taxes and fees
Country Yard Inn and Suite
Sikeston
6.8 out of 10, (118)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
Andrew
$56 nightly
The price is $64
Dec 9 - Dec 10
Total with taxes and fees
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
Cape Girardeau
9.6 out of 10, Exceptional, (44)
"This place is AWESOME! It's clean, artsy, fun, and if we ever have a chance, we will certainly return!"
Jordan S.
$132 nightly
The price is $138
Dec 9 - Dec 10
Total with taxes and fees
Rockwood Inn
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
Vanessa
$145 nightly
The price is $164
Dec 28 - Dec 29
Total with taxes and fees
Quaint, Beautiful Home next to SEMO and Hospital
Cape Girardeau
9.8 out of 10, Exceptional, (43)
"Location was perfect. The house was clean and met all our needs. Would definitely stay here again in the future."
Beau L.
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1)
"The host was very quick to respond and so great to work with for on our stay. "
Jessica S.
$296 nightly
The price is $296
Dec 9 - Dec 10
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Charleston Hotel Reviews
Pear Tree Inn Cape Girardeau Near the Medical Center
10/10 Excellent
Explore a world of travel with Expedia
- Diehlstadt Hotels
- Bertrand Hotels
- Motels in Bertrand
- 4 Star Hotels in Bertrand
- 3 Star Hotels in Bertrand
- 5 Star Hotels in Bertrand
- East Prairie Hotels
- Lodges in East Prairie
- Motels in East Prairie
- Vacation Homes in East Prairie
- Miner Hotels
- Hotels near The Book Bug
- Blodgett Hotels
- Hotels near Sikeston Memorial Municipal
- Sikeston Hotels
- Wyndham Hotels in Sikeston
- Hotels near Central Park
- Cheap Hotels in Sikeston
- Pet-friendly Hotels in Sikeston
- Hotels with an Indoor Pool in Sikeston
- Cabin Rentals in Sikeston
- Hotels with Hot Tubs in Sikeston
- Casino Hotels in Sikeston
- B&B in Sikeston
- Hotels with Restaurants in Sikeston
- Hotels with Kitchenettes in Sikeston
- Romantic Hotels in Sikeston
- 5 Star Hotels in Sikeston
- Luxury Hotels in Sikeston
- Hotels with Bars in Sikeston
- Resorts & Hotels with Spas in Sikeston
- Motels in Sikeston
- Hotels with Connecting Rooms in Sikeston
- Hotels with Laundry Facilities in Sikeston
- Hotel Wedding Venues Hotels in Sikeston
- Historic Hotels in Sikeston
- Family Hotels in Sikeston
- Gay friendly Hotels in Sikeston
- Hotels with Suites in Sikeston
- Hotels & Resorts for Couples in Sikeston
- Hotels with an Outdoor Pool in Sikeston
- Hotels with Free Breakfast in Sikeston
- 4 Star Hotels in Sikeston
- Hotels with a Pool in Sikeston
- Hotels with Balconies in Sikeston
- Vacation Homes in Sikeston
- Non-Smoking Hotels in Sikeston
- Extended Stay Hotels in Sikeston
- Cottages in Sikeston
- 3 Star Hotels in Sikeston
- Hotels with Tennis Courts in Sikeston
- Golf Hotels in Sikeston
- Hotels with a Gym in Sikeston
- Flights to Bertrand
- Flights from Bertrand
- Flights from Wyatt
- Flights from East Prairie
- Flights from Blodgett
- Flights from Sikeston Memorial Municipal
- Flights from Cape Girardeau (CGI) to Sikeston (SIK)
- Flights from Nashville (BNA) to Sikeston (SIK)
- Flights from Houston (IAH) to Sikeston (SIK)
- Flights from Chicago (ORD) to Sikeston (SIK)
- Flights from Dallas (DFW) to Sikeston (SIK)
- Flights from Minneapolis (MSP) to Sikeston (SIK)
- Flights from Detroit (DTW) to Sikeston (SIK)
- Flights from Orlando (MCO) to Sikeston (SIK)
- Flights from New Orleans (MSY) to Sikeston (SIK)
- Flights from Los Angeles (LAX) to Sikeston (SIK)
- Flights from Bowling Green (BWG) to Sikeston (SIK)
- Flights from Philadelphia (PHL) to Sikeston (SIK)
- Flights from New York (NYC) to Sikeston (SIK)
- Flights to Sikeston
- Flights from Sikeston
- Car rentals near Bertrand
- Car rentals near Wyatt
- Car rentals near East Prairie
- Car rentals near Miner
- Dollar Europe Rental Cars in Miner
- Car rentals near The Book Bug
- Car rentals near Blodgett
- Enterprise Rental Cars in Sikeston
- Hertz Rental Cars in Sikeston
- Car rentals near Sikeston
- Van Car Rentals in Sikeston
- Budget Rental Cars in Sikeston
- Avis Rental Cars in Sikeston
- Convertible Car Rentals in Sikeston
- Thrifty Car Rental Rental Cars in Sikeston