Find luxury hotels in St. Ann, MO

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Our top choices for St. Ann luxury hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very Good, (4013)
"Arch view room is big and comfortable fantastic. . "
United States
Tim
$84 nightly
The price is $99
Dec 29 - Dec 30
Total with taxes and fees
Hyatt Regency St. Louis at The Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1152)
"Really nice hotel!"
United States
DARIN
$87 nightly
The price is $104
Dec 19 - Dec 20
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1016)
"My second time staying there as always it was lovely "
United States
Nina
$103 nightly
The price is $122
Dec 22 - Dec 23
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (676)
"Small rooms but beautiful lobby. "
United States
Debbie
$119 nightly
The price is $140
Dec 19 - Dec 20
Total with taxes and fees
Le Méridien St. Louis Clayton

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1448)
"Awesome place to stay!!"
United States
Kaitlyn
$94 nightly
The price is $109
Dec 24 - Dec 25
Total with taxes and fees
River City Casino & Hotel

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1005)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
$166 nightly
The price is $194
Dec 21 - Dec 22
Total with taxes and fees
Ameristar Casino Resort and Spa

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very Good, (1056)
"Staff was courteous and the room was clean."
United States
Mia
$118 nightly
The price is $138
Jan 2 - Jan 3, 2026
Total with taxes and fees
Renaissance St. Louis Airport Hotel

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1036)
"Fun staff and a very cool hotel. Great room, too!"
United States
Christopher
$119 nightly
The price is $141
Dec 21 - Dec 22
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1916)
"Great service, unique hotel. Would absolutely stay again!"
United States
Michael
$148 nightly
The price is $176
Dec 16 - Dec 17
Total with taxes and fees
Moonrise Hotel

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1243)
"Great hospitality"
United States
Alejandro
$107 nightly
The price is $127
Dec 22 - Dec 23
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top St. Ann Hotel Reviews

Frequently asked questions

Are you searching for the perfect hotel for your luxury getaway to St. Ann?
Let Expedia help you arrange your flight to St. Louis Lambert Intl. Airport (STL) airport or St. Louis, MO (SUS-Spirit of St. Louis) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you want to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that St. Ann offers. During your visit, you might want to enjoy the restaurants and bars which St. Ann is known for.
When can I expect good weather in St. Ann?
Planning for the weather is an important factor for making your trip to St. Ann a success, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Ann is 50 inches.
What's there to see and do in St. Ann?
When you're in St. Ann, enjoy exploring the sights and attractions here including St. Louis Union Station, Gateway Arch, and Westport Plaza. If you have a bit of extra time while you're in the area, you might want to check out Hollywood Casino Amphitheatre and Blanche M. Touhill Performing Arts Center.

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