Title: The Best 5 Star Hotels in Isleworth from $163 | Expedia.com [Isleworth Travel Guide](https://expedia.com/Isleworth.dx10864)[Hotels in Isleworth](https://expedia.com/Isleworth-Hotels.d10864.Travel-Guide-Hotels)[Vacation Rentals in Isleworth](https://expedia.com/Isleworth-Vacation-Rentals.d10864.Travel-Guide-VacationRentals)[Flights to Isleworth](https://expedia.com/Cheap-Flights-To-Isleworth.d10864.Travel-Guide-Flights)[Things to do in Isleworth](https://expedia.com/Things-To-Do-In-Isleworth.d10864.Travel-Guide-Activities)[Car Rentals in Isleworth](https://expedia.com/Car-Rentals-In-Isleworth.d10864.Car-Rental-Guide)[Isleworth Vacation Packages](https://expedia.com/Isleworth.d10864.Destination-Travel-Guides) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Maxwell Hamilton ![](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Isleworth 5 Star Hotels Tonight [Mar 10 - Mar 11](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-10&endDate=2026-03-11&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 11 - Mar 12](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-11&endDate=2026-03-12&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isleworth 5-star hotels ![View from room](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/e09d8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/9d683740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/15070c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Garden Hotel [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) London City Centre 9.2/10 Wonderful (1,865 reviews) "Lovely stay, will definitely stay again. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Susan $195 nightly $234 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/6026e0f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/409fec75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/f318e22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![English breakfast on weekdays (GBP 20 per person)](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/0447799c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel London Heathrow [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) Heathrow Villages 8.8/10 Excellent (4,974 reviews) "Convenient location, helpful staff, comfortable room, great food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine $199 nightly $239 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/d00975c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Saijoukai Suite | View from room](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/6cc5079f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Japanese cuisine](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/42284ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/988abfd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu London Portman Square [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) London City Centre 9.0/10 Wonderful (458 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janette $317 nightly $381 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4c05e12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/87b8b029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/f6a333fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite | View from room](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/bb16e719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Standard London [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) London City Centre 9.2/10 Wonderful (1,686 reviews) "Great hotel. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Greg $260 nightly $312 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/bda072e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/w2998h2250x2y0-e555bea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Garden Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/c5863f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/64960824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St Martins Lane London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) London City Centre 9.4/10 Exceptional (1,010 reviews) "Always a warm welcome and super comfy beds " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) William $275 nightly $330 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/ddf11236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/b80e5543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/0554ee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily English breakfast (GBP 35 per person)](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/6bfa0679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Lancaster London [](https://www.expedia.com/London-Hotels-Royal-Lancaster-London.h518026.Hotel-Information) London City Centre 9.6/10 Exceptional (1,019 reviews) "Very good location and room exceeded my expectations " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix $246 nightly $295 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Lancaster-London.h518026.Hotel-Information) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/53671bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/0b506dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/f1cb5578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/852c4beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kaya Great Northern Hotel [](https://www.expedia.com/London-Hotels-Kaya-Great-Northern-Hotel.h5921175.Hotel-Information) London City Centre 8.8/10 Excellent (1,011 reviews) "Nice room, clean and well laid out " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Jonathan $226 nightly $272 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Kaya-Great-Northern-Hotel.h5921175.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/2fa787ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/747978d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/3b80b7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/c333d282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Middle Eight - Covent Garden - Preferred Hotels and Resorts [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) London City Centre 9.4/10 Exceptional (1,535 reviews) "we loved everything here and what a great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan $300 nightly $360 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/82f4f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, steam room, body treatments, body wraps](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/3520f597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/ea1ddd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, pub, cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/699fc530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Langham, London [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) London City Centre 9.6/10 Exceptional (1,006 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) NEIL $534 nightly $641 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) ![Rooftop bar](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/fe8d3979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/42a448ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/6065b753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/dedf9cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Londoner [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) London City Centre 9.4/10 Exceptional (1,011 reviews) "Great Hotel in great position and super clean, simply love it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Valentina $438 nightly $525 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5964h3835x0y5-6b0ac613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5755h3835x5y5-b98050e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/a3817d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/193d65e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency London The Churchill [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) London City Centre 9.0/10 Wonderful (1,006 reviews) "Room is meticulous, staff is highly attentive, lovely stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah $385 nightly $462 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) ![Daily English breakfast (GBP 45 per person)](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/dee77aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/9ca37fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room | Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/e8a9d2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/f30e82e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rubens at the Palace [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) London City Centre 9.2/10 Wonderful (1,021 reviews) "It was very good definitely will be back again! " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Zozan $224 nightly $269 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/a2216a6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Junior Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, free minibar items](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/ee68fa5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/4133b88a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Egyptian cotton sheets, premium bedding, free minibar items](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/0aa4a7cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Berkeley, Maybourne [](https://www.expedia.com/London-Hotels-The-Berkeley.h5685.Hotel-Information) London City Centre 9.2/10 Wonderful (282 reviews) "Outstanding!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Wesley $839 nightly $1,007 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Berkeley.h5685.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/ffd90ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/22be8162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/d66da358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![East End Balcony Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/cdc0357b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aethos Hotel London Shoreditch [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) London City Centre 9.8/10 Exceptional (82 reviews) "great room location restaurant " ![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg) TOSHIHIKO $227 nightly $273 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/aab668ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/ef9667ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Club Twin Room | In-room safe, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/bc4f5897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/0d6c7c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montcalm Chilworth Townhouse, Paddington [](https://www.expedia.com/London-Hotels-The-Chilworth-London-Paddington.h901179.Hotel-Information) London City Centre 8.2/10 Very Good (1,006 reviews) "Excellent hotel and great for price" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Mattia $136 nightly $163 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Chilworth-London-Paddington.h901179.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/1766431a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/b8d3eef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Suite | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/273144dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/w2998h2250x2y0-31f0e52c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanderson London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) London City Centre 8.8/10 Excellent (1,008 reviews) "Very clean room, excellent friendly staff, all bathroom features worked perfectly," ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LEO $284 nightly $341 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) ![Suite, 1 Bedroom, Terrace | View from room](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/b655f5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/44a7a8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/2130619e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/36d73476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The May Fair, A Radisson Collection Hotel, Mayfair London [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) London City Centre 8.8/10 Excellent (1,006 reviews) "Enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DANIEL $278 nightly $334 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/f03f99a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Premium bedding, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/109743a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/90869620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/666f9324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vintry & Mercer Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) London City Centre 9.8/10 Exceptional (1,005 reviews) "Rooms immaculate and super friendly staff" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maxine $205 nightly $247 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/76a121e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/4837b788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Premium bedding, free minibar, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/edfb9665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/a6226682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ampersand Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) London City Centre 9.6/10 Exceptional (1,009 reviews) "Great hotel & staff, comfortable bed. Really great area" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Mitchell $206 nightly $248 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/890d685c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/w3835h2180x0y5-bd7f5066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/2c6ec772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/834f7d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) London City Centre 8.6/10 Excellent (968 reviews) "Amazing staff, beautiful architecture and excellent restaurant!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jaskiran $157 nightly $188 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Isleworth. ![Strand Palace Hotel](https://images.trvl-media.com/lodging/1000000/10000/200/179/6848fd94_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Strand Palace Hotel 372 The Strand London England $170 nightly $205 total Mar 15 - Mar 16 Total with taxes and fees 9/10 Wonderful! (5,013 reviews) [](https://expedia.com/London-Hotels-The-Strand-Palace-Hotel.h179.Hotel-Information) ![The Tower Hotel, by Thistle](https://images.trvl-media.com/lodging/1000000/10000/2500/2479/717976c5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Tower Hotel, by Thistle St Katharine's Way London England $139 nightly $167 total Mar 15 - Mar 16 Total with taxes and fees 8.2/10 Very Good! (9,516 reviews) [](https://expedia.com/London-Hotels-The-Tower-Hotel.h2479.Hotel-Information) ![The Royal Horseguards, London](https://images.trvl-media.com/lodging/1000000/30000/26000/25926/1f40d817_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Royal Horseguards, London 2 Whitehall Court London England $232 nightly $278 total Mar 29 - Mar 30 Total with taxes and fees 9.2/10 Wonderful! (2,176 reviews) [](https://expedia.com/London-Hotels-The-Royal-Horseguards.h25926.Hotel-Information) Still don't see what you're looking for? [See all properties in Isleworth.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=10864&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=10864&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=10864&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=10864&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=10864&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F11%2F2026&endDate=3%2F12%2F2026®ionId=10864&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Isleworth Tucked along the Thames, this historic riverside town offers peaceful walks past Syon House's magnificent gardens and the charming Old Isleworth pubs. Catch a rugby match at nearby Twickenham Stadium or explore the London Museum of Water and Steam where Victorian pumping engines still operate. [See all hotels in Isleworth](https://www.expedia.com/Hotel-Search?startDate=2026-03-24&endDate=2026-03-25&adults=2®ionId=10864) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=900&h=598&p=1&q=high) Photo by Maxwell Hamilton ## Top Isleworth Hotel Reviews ![Royal Garden Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58_y.jpg) ### Royal Garden Hotel 10/10 Excellent "The hotel staff were fantastic. The rooms were clean, the breakfast was amazing daily. The location was fantastic. Couldn’t ask for a nicer property." [](https://expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Sea Containers London](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637_y.jpg) ### Sea Containers London 10/10 Excellent "From checking in to checking out the following day most things were wonderful. The staff so friendly and helpful. Lovely room/bathroom and service and drinks in the 12th floor bar. The only downside was the breakfast, we had to wait absolutely ages for a coffee but the lady was very apologetic and we hadn't been told there was actually a help yourself coffee machine at the other end of the breakfast room. For the price of the breakfast we all thought it was rather substandard with not enough choices of fruit/meats/cheeses which for a hotel of this standard sadly lacked." [](https://expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ## Find out more about Isleworth Ready to experience the next standard in luxury? We know you're thinking about it. Add an extra layer of enjoyment on your next trip to Isleworth by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Isleworth any longer. You'll join the multitudes of vacationers who have made Isleworth so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Isleworth and get ready to be pampered like never before. ### Book the Best Isleworth 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you suggest the next attraction to visit? A Swedish massage to help your cares fall away? Fluffy down pillows, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Isleworth are waiting for you to relax after an exciting day. ### Make Your Escape The results are in, and Isleworth 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Isleworth 5-star hotels today and soothe yourself in total tranquility tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Isleworth? ### How much does it cost to stay in a 5-star hotel in Isleworth? > - Search for the lowest price per night from $167 ### What makes a hotel 5 stars in Isleworth? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Isleworth Recreation Centre ](https://www.expedia.com/Isleworth-Recreation-Centre-Hotels.0-l553248621532491841-0.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in St. Margarets and North Twickenham ](https://www.expedia.com/St-Margarets-And-North-Twickenham-London-Hotels-LGBT-Welcoming-Hotel.0-n553248635976382080-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Houseboats in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Houseboats.d553248634668496880-aaHouseboats.Travel-Guide-Accommodation) - [Aparthotels in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Apart-Hotels.d553248634668496880-aaApartHotels.Travel-Guide-Accommodation) - 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