Title: The Best 5 Star Hotels in Isleworth from $95 | Expedia.com [Isleworth Travel Guide](https://expedia.com/Isleworth.dx10864)[Hotels in Isleworth](https://expedia.com/Isleworth-Hotels.d10864.Travel-Guide-Hotels)[Vacation Rentals in Isleworth](https://expedia.com/Isleworth-Vacation-Rentals.d10864.Travel-Guide-VacationRentals)[Flights to Isleworth](https://expedia.com/Cheap-Flights-To-Isleworth.d10864.Travel-Guide-Flights)[Things to do in Isleworth](https://expedia.com/Things-To-Do-In-Isleworth.d10864.Travel-Guide-Activities)[Car Rentals in Isleworth](https://expedia.com/Car-Rentals-In-Isleworth.d10864.Car-Rental-Guide)[Isleworth Vacation Packages](https://expedia.com/Isleworth.d10864.Destination-Travel-Guides) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Maxwell Hamilton ![](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Isleworth 5 Star Hotels Tonight [Mar 13 - Mar 14](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-13&endDate=2026-03-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 14 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-14&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isleworth 5-star hotels ![View from room](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/15070c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/9d683740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/70dac539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Garden Hotel [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) London City Centre 9.2/10 Wonderful (1,843 reviews) "We loved our stay here! Lovely view of London and loved being in this part of town. Would definitely stay here again when we return!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Destiny $223 nightly $268 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/6026e0f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/f318e22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![English breakfast on weekdays (GBP 20 per person)](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/0447799c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/409fec75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel London Heathrow [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) Heathrow Villages 8.8/10 Excellent (4,957 reviews) "We thoroughly enjoyed our stay. We traveled from Arizona and we will most definitely be returning. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheri $201 nightly $242 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Riverview Studio Suite | Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/1e715d68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/a8f10074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/ed6de058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Containers London [](https://www.expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) London City Centre 9.4/10 Exceptional (2,429 reviews) "Best hotel I’ve stayed in whilst visiting London. Great room, fantastic breakfast and the most friendly team you could ever meet. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) David $213 nightly $255 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4c05e12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/f6a333fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4f34d2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/87b8b029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Standard London [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) London City Centre 9.2/10 Wonderful (1,670 reviews) "Lovely hotel that was most welcoming " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) moira $264 nightly $316 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/890d685c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/834f7d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/ca6fe65c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/2c6ec772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) London City Centre 8.6/10 Excellent (971 reviews) "Amazing staff, beautiful architecture and excellent restaurant!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jaskiran $150 nightly $180 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) ![Rooftop bar](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/fe8d3979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/42a448ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, free cabanas](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/4e8c76a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/dedf9cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Londoner [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) London City Centre 9.4/10 Exceptional (1,000 reviews) "Great Hotel in great position and super clean, simply love it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Valentina $435 nightly $522 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/bda072e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/w2998h2250x2y0-e555bea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/96782a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/64960824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St Martins Lane London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) London City Centre 9.4/10 Exceptional (1,000 reviews) "Really nice place to stay. It’s well located (theaters, restaurants, underground station) " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stephane $311 nightly $373 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/d00975c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Japanese cuisine](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/42284ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/988abfd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Saijoukai Suite | View from room](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/6cc5079f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu London Portman Square [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) London City Centre 9.0/10 Wonderful (458 reviews) "Excellent joice to stay in London " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Daniela $251 nightly $302 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/82f4f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, pub, cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/699fc530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/80e0da06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/ea1ddd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Langham, London [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) London City Centre 9.6/10 Exceptional (1,000 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) NEIL $612 nightly $734 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5964h3835x0y5-6b0ac613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/a3817d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5755h3835x5y5-b98050e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/1b99c5b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency London The Churchill [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) London City Centre 9.0/10 Wonderful (1,000 reviews) "Room is meticulous, staff is highly attentive, lovely stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah $383 nightly $459 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/2fa787ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/c333d282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/3b80b7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/98bd7043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Middle Eight - Covent Garden - Preferred Hotels and Resorts [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) London City Centre 9.4/10 Exceptional (1,524 reviews) "we loved everything here and what a great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan $292 nightly $351 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/4f7f4d0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/9ee45b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/3326bd25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/8f9c6f46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Grosvenor House London [](https://www.expedia.com/London-Hotels-JW-Marriott-Grosvenor-House-London.h25578.Hotel-Information) London City Centre 8.8/10 Excellent (841 reviews) "Great location. Loved the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anar $435 nightly $521 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-JW-Marriott-Grosvenor-House-London.h25578.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/ffd90ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/d66da358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/dd626e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![East End Balcony Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/cdc0357b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aethos Hotel London Shoreditch [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) London City Centre 9.8/10 Exceptional (83 reviews) "Very clean property, well designed, excellent location, delicious breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather $226 nightly $271 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/1766431a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/w2998h2250x2y0-31f0e52c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/b8d3eef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/93831e6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanderson London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) London City Centre 8.8/10 Excellent (1,000 reviews) "This was a great little hotel. The staff was very helpful. The restaurant served a very nice lunch and dinner and the bar always served delicious cocktails. Rooms are nice and clean and surprisingly spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa $283 nightly $339 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) ![Classic Room | Premium bedding, free minibar, in-room safe, desk](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/1fbbbb7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/43609f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Designer toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/567d87eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/495865b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mayfair Townhouse [](https://www.expedia.com/London-Hotels-The-Mayfair-Townhouse.h57972013.Hotel-Information) London City Centre 9.2/10 Wonderful (1,180 reviews) "Spotless rooms, amazing staff and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marielis $272 nightly $327 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Mayfair-Townhouse.h57972013.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/f03f99a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/666f9324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/90869620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/e916b08e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vintry & Mercer Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) London City Centre 9.8/10 Exceptional (1,001 reviews) "Rooms immaculate and super friendly staff" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maxine $205 nightly $246 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/76a121e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/02c8af79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/a6226682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/4837b788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ampersand Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) London City Centre 9.6/10 Exceptional (1,000 reviews) "great neighbourhood and great staff especially Jerry!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Melanie $206 nightly $247 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/0aee3469.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/47b42de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/1ebd2ead.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/4b94024c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hari [](https://www.expedia.com/London-Hotels-The-Hari.h3657.Hotel-Information) London City Centre 9.4/10 Exceptional (748 reviews) "Hotel was wonderful. Staff and management the best. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Neil $359 nightly $431 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Hari.h3657.Hotel-Information) ![Daily English breakfast (GBP 45 per person)](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/dee77aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room | Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/e8a9d2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/f30e82e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/c2010fd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rubens at the Palace [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) London City Centre 9.2/10 Wonderful (1,001 reviews) "Amazing property and even better staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Azza $207 nightly $249 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) ![Suite, 1 Bedroom, Terrace | View from room](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/b655f5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/44a7a8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/36d73476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/560d2d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The May Fair, A Radisson Collection Hotel, Mayfair London [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) London City Centre 8.8/10 Excellent (1,002 reviews) "Enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DANIEL $307 nightly $368 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Isleworth. ![Strand Palace Hotel](https://images.trvl-media.com/lodging/1000000/10000/200/179/6848fd94_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Strand Palace Hotel 372 The Strand London England $146 nightly $176 total Mar 29 - Mar 30 Total with taxes and fees 9/10 Wonderful! (4,980 reviews) [](https://expedia.com/London-Hotels-The-Strand-Palace-Hotel.h179.Hotel-Information) ![The Tower Hotel, by Thistle](https://images.trvl-media.com/lodging/1000000/10000/2500/2479/717976c5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Tower Hotel, by Thistle St Katharine's Way London England $138 nightly $166 total Mar 22 - Mar 23 Total with taxes and fees 8.2/10 Very Good! (9,487 reviews) [](https://expedia.com/London-Hotels-The-Tower-Hotel.h2479.Hotel-Information) ![Copthorne Tara Hotel London Kensington](https://images.trvl-media.com/lodging/1000000/30000/26200/26145/a8cf46a6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Copthorne Tara Hotel London Kensington Scarsdale Place London England $79 nightly $95 total Mar 15 - Mar 16 Total with taxes and fees 7.8/10 Good! (3,531 reviews) [](https://expedia.com/London-Hotels-Copthorne-Tara-Hotel-London-Kensington.h26145.Hotel-Information) Still don't see what you're looking for? [See all properties in Isleworth.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=10864&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=10864&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=10864&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=10864&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=10864&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=10864&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Isleworth Tucked along the Thames, this historic riverside town offers peaceful walks past Syon House's magnificent gardens and the charming Old Isleworth pubs. Catch a rugby match at nearby Twickenham Stadium or explore the London Museum of Water and Steam where Victorian pumping engines still operate. [See all hotels in Isleworth](https://www.expedia.com/Hotel-Search?startDate=2026-03-27&endDate=2026-03-28&adults=2®ionId=10864) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=900&h=598&p=1&q=high) Photo by Maxwell Hamilton ## Top Isleworth Hotel Reviews ![Royal Garden Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58_y.jpg) ### Royal Garden Hotel 10/10 Excellent "Doormen we very friendly, service was excellent when we needed more water or items for the room" [](https://expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Sea Containers London](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637_y.jpg) ### Sea Containers London 10/10 Excellent "From checking in to checking out the following day most things were wonderful. The staff so friendly and helpful. Lovely room/bathroom and service and drinks in the 12th floor bar. The only downside was the breakfast, we had to wait absolutely ages for a coffee but the lady was very apologetic and we hadn't been told there was actually a help yourself coffee machine at the other end of the breakfast room. For the price of the breakfast we all thought it was rather substandard with not enough choices of fruit/meats/cheeses which for a hotel of this standard sadly lacked." [](https://expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ## Find out more about Isleworth Ready to experience the next standard in luxury? We know you're thinking about it. Add an extra layer of enjoyment on your next trip to Isleworth by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Isleworth any longer. You'll join the multitudes of vacationers who have made Isleworth so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Isleworth and get ready to be pampered like never before. ### Book the Best Isleworth 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you suggest the next attraction to visit? A Swedish massage to help your cares fall away? Fluffy down pillows, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Isleworth are waiting for you to relax after an exciting day. ### Make Your Escape The results are in, and Isleworth 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Isleworth 5-star hotels today and soothe yourself in total tranquility tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Isleworth? ### How much does it cost to stay in a 5-star hotel in Isleworth? > - Search for the lowest price per night from $95 ### What makes a hotel 5 stars in Isleworth? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Isleworth Recreation Centre ](https://www.expedia.com/Isleworth-Recreation-Centre-Hotels.0-l553248621532491841-0.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in St. Margarets and North Twickenham ](https://www.expedia.com/St-Margarets-And-North-Twickenham-London-Hotels-LGBT-Welcoming-Hotel.0-n553248635976382080-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Houseboats in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Houseboats.d553248634668496880-aaHouseboats.Travel-Guide-Accommodation) - [Aparthotels in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Apart-Hotels.d553248634668496880-aaApartHotels.Travel-Guide-Accommodation) - 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