Title: The Best 5 Star Hotels in Isleworth from $94 | Expedia.com [Isleworth Travel Guide](https://expedia.com/Isleworth.dx10864)[Hotels in Isleworth](https://expedia.com/Isleworth-Hotels.d10864.Travel-Guide-Hotels)[Vacation Rentals in Isleworth](https://expedia.com/Isleworth-Vacation-Rentals.d10864.Travel-Guide-VacationRentals)[Flights to Isleworth](https://expedia.com/Cheap-Flights-To-Isleworth.d10864.Travel-Guide-Flights)[Things to do in Isleworth](https://expedia.com/Things-To-Do-In-Isleworth.d10864.Travel-Guide-Activities)[Car Rentals in Isleworth](https://expedia.com/Car-Rentals-In-Isleworth.d10864.Car-Rental-Guide)[Isleworth Vacation Packages](https://expedia.com/Isleworth.d10864.Destination-Travel-Guides) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Maxwell Hamilton ![](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Isleworth 5 Star Hotels Tonight [Mar 18 - Mar 19](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-18&endDate=2026-03-19&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 19 - Mar 20](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-19&endDate=2026-03-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isleworth 5-star hotels ![View from room](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/9d683740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/15070c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/70dac539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Garden Hotel [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) London City Centre 9.2/10 Wonderful (1,850 reviews) "Fantastic staff, amazing room view and location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lisa $216 nightly $259 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/6026e0f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/f318e22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![English breakfast on weekdays (GBP 20 per person)](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/0447799c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/07bd4fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel London Heathrow [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) Heathrow Villages 8.8/10 Excellent (4,963 reviews) "Amazing stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kevin $200 nightly $240 total Apr 18 - Apr 19 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) ![2 bars/lounges, rooftop bar, cocktail bar](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/0d683072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Riverview Studio Suite | Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/1e715d68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; British cuisine, alfresco dining ](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/63eb30c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Containers London [](https://www.expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) London City Centre 9.4/10 Exceptional (2,436 reviews) "Great stay! Staff is amazing, rooms were clean, nice shower, location was perfect! Planning to stay again next time I’m in town. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonia $213 nightly $255 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4c05e12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/f6a333fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4f34d2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite | View from room](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/bb16e719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Standard London [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) London City Centre 9.2/10 Wonderful (1,676 reviews) "Lovely hotel that was most welcoming " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) moira $245 nightly $295 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/890d685c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/834f7d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/2c6ec772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/w3835h2180x0y5-bd7f5066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) London City Centre 8.6/10 Excellent (974 reviews) "Amazing staff, beautiful architecture and excellent restaurant!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jaskiran $160 nightly $192 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) ![Rooftop bar](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/fe8d3979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, free cabanas](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/4e8c76a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/42a448ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/6065b753.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Londoner [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) London City Centre 9.4/10 Exceptional (1,008 reviews) "Great Hotel in great position and super clean, simply love it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Valentina $436 nightly $523 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/bda072e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/96782a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/w2998h2250x2y0-e555bea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/64960824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St Martins Lane London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) London City Centre 9.4/10 Exceptional (1,006 reviews) "Really nice place to stay. It’s well located (theaters, restaurants, underground station) " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stephane $311 nightly $374 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/d00975c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/988abfd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/bd86ccc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Saijoukai Suite | View from room](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/6cc5079f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu London Portman Square [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) London City Centre 9.0/10 Wonderful (460 reviews) "Excellent joice to stay in London " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Daniela $321 nightly $386 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/82f4f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/ea1ddd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/80e0da06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, steam room, body treatments, body wraps](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/3520f597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Langham, London [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) London City Centre 9.6/10 Exceptional (1,000 reviews) "Great location with great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thanh Uyen $611 nightly $733 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5964h3835x0y5-6b0ac613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5755h3835x5y5-b98050e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/a3817d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/193d65e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency London The Churchill [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) London City Centre 9.0/10 Wonderful (1,000 reviews) "Room is meticulous, staff is highly attentive, lovely stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah $383 nightly $460 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/2fa787ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/3b80b7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/98bd7043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/c333d282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Middle Eight - Covent Garden - Preferred Hotels and Resorts [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) London City Centre 9.4/10 Exceptional (1,535 reviews) "Fantastic stay in a beautiful hotel, staff were brilliant and very helpful, loved every second. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Trevor $264 nightly $317 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/4f7f4d0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/8f9c6f46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/9ee45b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/1000000/30000/25600/25578/cd11b503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JW Marriott Grosvenor House London [](https://www.expedia.com/London-Hotels-JW-Marriott-Grosvenor-House-London.h25578.Hotel-Information) London City Centre 8.8/10 Excellent (842 reviews) "Great location. Loved the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anar $421 nightly $505 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/London-Hotels-JW-Marriott-Grosvenor-House-London.h25578.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/ffd90ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![East End Balcony Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/cdc0357b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/dd626e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/22be8162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aethos Hotel London Shoreditch [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) London City Centre 9.8/10 Exceptional (88 reviews) "Very clean property, well designed, excellent location, delicious breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather $226 nightly $271 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/1766431a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/b8d3eef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Suite | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/273144dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/w2998h2250x2y0-31f0e52c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanderson London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) London City Centre 8.8/10 Excellent (1,004 reviews) "This was a great little hotel. The staff was very helpful. The restaurant served a very nice lunch and dinner and the bar always served delicious cocktails. Rooms are nice and clean and surprisingly spacious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa $283 nightly $340 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) ![Classic Room | Premium bedding, free minibar, in-room safe, desk](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/1fbbbb7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/495865b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/43609f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Designer toiletries, hair dryer, bathrobes, slippers](https://images.trvl-media.com/lodging/58000000/57980000/57972100/57972013/567d87eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mayfair Townhouse [](https://www.expedia.com/London-Hotels-The-Mayfair-Townhouse.h57972013.Hotel-Information) London City Centre 9.2/10 Wonderful (1,190 reviews) "Spotless rooms, amazing staff and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marielis $283 nightly $340 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Mayfair-Townhouse.h57972013.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/f03f99a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/666f9324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/e916b08e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Premium bedding, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/109743a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vintry & Mercer Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) London City Centre 9.8/10 Exceptional (1,000 reviews) "Rooms immaculate and super friendly staff" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maxine $204 nightly $244 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/76a121e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Premium bedding, free minibar, in-room safe, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/edfb9665.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/4837b788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/02c8af79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ampersand Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) London City Centre 9.6/10 Exceptional (1,002 reviews) "Our stay was perfect! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marelyn $228 nightly $274 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/0aee3469.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/93637095.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/4b94024c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3700/3657/47b42de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hari [](https://www.expedia.com/London-Hotels-The-Hari.h3657.Hotel-Information) London City Centre 9.4/10 Exceptional (748 reviews) "Hotel was wonderful. Staff and management the best. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Neil $360 nightly $432 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Hari.h3657.Hotel-Information) ![Daily English breakfast (GBP 45 per person)](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/dee77aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/c2010fd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/f30e82e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room | Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/e8a9d2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rubens at the Palace [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) London City Centre 9.2/10 Wonderful (1,013 reviews) "Amazing property and even better staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Azza $207 nightly $249 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) ![Suite, 1 Bedroom, Terrace | View from room](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/b655f5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/560d2d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/44a7a8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/36d73476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The May Fair, A Radisson Collection Hotel, Mayfair London [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) London City Centre 8.8/10 Excellent (1,003 reviews) "Enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DANIEL $298 nightly $358 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Isleworth. ![Strand Palace Hotel](https://images.trvl-media.com/lodging/1000000/10000/200/179/6848fd94_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Strand Palace Hotel 372 The Strand London England $143 nightly $172 total Mar 29 - Mar 30 Total with taxes and fees 9/10 Wonderful! (4,981 reviews) [](https://expedia.com/London-Hotels-The-Strand-Palace-Hotel.h179.Hotel-Information) ![The Tower Hotel, by Thistle](https://images.trvl-media.com/lodging/1000000/10000/2500/2479/717976c5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Tower Hotel, by Thistle St Katharine's Way London England $138 nightly $166 total Apr 5 - Apr 6 Total with taxes and fees 8.2/10 Very Good! (9,517 reviews) [](https://expedia.com/London-Hotels-The-Tower-Hotel.h2479.Hotel-Information) ![Copthorne Tara Hotel London Kensington](https://images.trvl-media.com/lodging/1000000/30000/26200/26145/a8cf46a6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Copthorne Tara Hotel London Kensington Scarsdale Place London England $79 nightly $94 total Mar 23 - Mar 24 Total with taxes and fees 7.8/10 Good! (3,548 reviews) [](https://expedia.com/London-Hotels-Copthorne-Tara-Hotel-London-Kensington.h26145.Hotel-Information) Still don't see what you're looking for? [See all properties in Isleworth.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=10864&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=10864&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=10864&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=10864&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=10864&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F19%2F2026&endDate=3%2F20%2F2026®ionId=10864&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Isleworth Tucked along the Thames, this historic riverside town offers peaceful walks past Syon House's magnificent gardens and the charming Old Isleworth pubs. Catch a rugby match at nearby Twickenham Stadium or explore the London Museum of Water and Steam where Victorian pumping engines still operate. [See all hotels in Isleworth](https://www.expedia.com/Hotel-Search?startDate=2026-04-01&endDate=2026-04-02&adults=2®ionId=10864) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=900&h=598&p=1&q=high) Photo by Maxwell Hamilton ## Top Isleworth Hotel Reviews ![Sea Containers London](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637_y.jpg) ### Sea Containers London 10/10 Excellent "Great value for money, nice and quiet and great location" [](https://expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ![Royal Garden Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58_y.jpg) ### Royal Garden Hotel 10/10 Excellent "The gym was dark and could be cleaner. Some broken equipment " [](https://expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ## Find out more about Isleworth Ready to experience the next standard in luxury? We know you're thinking about it. Add an extra layer of enjoyment on your next trip to Isleworth by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Isleworth any longer. You'll join the multitudes of vacationers who have made Isleworth so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Isleworth and get ready to be pampered like never before. ### Book the Best Isleworth 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you suggest the next attraction to visit? A Swedish massage to help your cares fall away? Fluffy down pillows, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Isleworth are waiting for you to relax after an exciting day. ### Make Your Escape The results are in, and Isleworth 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Isleworth 5-star hotels today and soothe yourself in total tranquility tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Isleworth? ### How much does it cost to stay in a 5-star hotel in Isleworth? > - Search for the lowest price per night from $94 ### What makes a hotel 5 stars in Isleworth? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Isleworth Recreation Centre ](https://www.expedia.com/Isleworth-Recreation-Centre-Hotels.0-l553248621532491841-0.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in St. Margarets and North Twickenham ](https://www.expedia.com/St-Margarets-And-North-Twickenham-London-Hotels-LGBT-Welcoming-Hotel.0-n553248635976382080-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Houseboats in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Houseboats.d553248634668496880-aaHouseboats.Travel-Guide-Accommodation) - [Aparthotels in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Apart-Hotels.d553248634668496880-aaApartHotels.Travel-Guide-Accommodation) - 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