Title: The Best 5 Star Hotels in Isleworth from $162 | Expedia.com [Isleworth Travel Guide](https://expedia.com/Isleworth.dx10864)[Hotels in Isleworth](https://expedia.com/Isleworth-Hotels.d10864.Travel-Guide-Hotels)[Vacation Rentals in Isleworth](https://expedia.com/Isleworth-Vacation-Rentals.d10864.Travel-Guide-VacationRentals)[Flights to Isleworth](https://expedia.com/Cheap-Flights-To-Isleworth.d10864.Travel-Guide-Flights)[Things to do in Isleworth](https://expedia.com/Things-To-Do-In-Isleworth.d10864.Travel-Guide-Activities)[Car Rentals in Isleworth](https://expedia.com/Car-Rentals-In-Isleworth.d10864.Car-Rental-Guide)[Isleworth Vacation Packages](https://expedia.com/Isleworth.d10864.Destination-Travel-Guides) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Maxwell Hamilton ![](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Isleworth 5 Star Hotels Tonight [Mar 7 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-07&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 8 - Mar 9](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-08&endDate=2026-03-09&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isleworth 5-star hotels ![View from room](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/e09d8fca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/70dac539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/15070c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Garden Hotel [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) London City Centre 9.2/10 Wonderful (1,858 reviews) "Lovely stay, will definitely stay again. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Susan $205 nightly $246 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/6026e0f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/f318e22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/07bd4fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![English breakfast on weekdays (GBP 20 per person)](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/0447799c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel London Heathrow [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) Heathrow Villages 8.8/10 Excellent (4,965 reviews) "Convenient location, helpful staff, comfortable room, great food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine $199 nightly $239 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/d00975c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/bd86ccc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Saijoukai Suite | View from room](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/6cc5079f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Japanese cuisine](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/42284ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu London Portman Square [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) London City Centre 9.0/10 Wonderful (457 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janette $297 nightly $357 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4c05e12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/87b8b029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4f34d2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite | View from room](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/bb16e719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Standard London [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) London City Centre 9.2/10 Wonderful (1,681 reviews) "Great hotel. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Greg $263 nightly $315 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/bda072e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/64960824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Garden Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/c5863f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/w2998h2250x2y0-e555bea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St Martins Lane London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) London City Centre 9.4/10 Exceptional (1,010 reviews) "Always a warm welcome and super comfy beds " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) William $275 nightly $329 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/ddf11236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/0554ee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/b80e5543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily English breakfast (GBP 35 per person)](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/6bfa0679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Lancaster London [](https://www.expedia.com/London-Hotels-Royal-Lancaster-London.h518026.Hotel-Information) London City Centre 9.6/10 Exceptional (1,016 reviews) "Very good location and room exceeded my expectations " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix $256 nightly $307 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Lancaster-London.h518026.Hotel-Information) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/53671bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; British cuisine ](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/4060269f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/f1cb5578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/0b506dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kaya Great Northern Hotel [](https://www.expedia.com/London-Hotels-Kaya-Great-Northern-Hotel.h5921175.Hotel-Information) London City Centre 8.8/10 Excellent (1,009 reviews) "Nice room, clean and well laid out " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Jonathan $236 nightly $284 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Kaya-Great-Northern-Hotel.h5921175.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/2fa787ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/98bd7043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/3b80b7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/c333d282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Middle Eight - Covent Garden - Preferred Hotels and Resorts [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) London City Centre 9.4/10 Exceptional (1,531 reviews) "we loved everything here and what a great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan $313 nightly $375 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/82f4f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, pub, cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/699fc530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, steam room, body treatments, body wraps](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/3520f597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/ea1ddd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Langham, London [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) London City Centre 9.6/10 Exceptional (1,006 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) NEIL $503 nightly $604 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) ![Rooftop bar](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/fe8d3979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/42a448ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/dedf9cdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, free cabanas](https://images.trvl-media.com/lodging/46000000/45870000/45864400/45864335/4e8c76a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Londoner [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) London City Centre 9.4/10 Exceptional (1,010 reviews) "Great Hotel in great position and super clean, simply love it" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Valentina $437 nightly $525 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Londoner.h45864335.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5964h3835x0y5-6b0ac613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5755h3835x5y5-b98050e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/193d65e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/1b99c5b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency London The Churchill [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) London City Centre 9.0/10 Wonderful (1,006 reviews) "Room is meticulous, staff is highly attentive, lovely stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sarah $384 nightly $461 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) ![Daily English breakfast (GBP 45 per person)](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/dee77aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room | Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/e8a9d2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/9ca37fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/c2010fd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rubens at the Palace [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) London City Centre 9.2/10 Wonderful (1,017 reviews) "It was very good definitely will be back again! " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Zozan $235 nightly $283 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/a2216a6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/4133b88a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Junior Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, free minibar items](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/ee68fa5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, free cabanas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/950c8a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Berkeley, Maybourne [](https://www.expedia.com/London-Hotels-The-Berkeley.h5685.Hotel-Information) London City Centre 9.2/10 Wonderful (282 reviews) "Outstanding!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Wesley $846 nightly $1,016 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Berkeley.h5685.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/ffd90ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/22be8162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/d66da358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/dd626e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aethos Hotel London Shoreditch [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) London City Centre 9.6/10 Exceptional (78 reviews) "great room location restaurant " ![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg) TOSHIHIKO $227 nightly $272 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/aab668ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/f8f85053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Club Twin Room | In-room safe, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/bc4f5897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/0d6c7c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montcalm Chilworth Townhouse, Paddington [](https://www.expedia.com/London-Hotels-The-Chilworth-London-Paddington.h901179.Hotel-Information) London City Centre 8.2/10 Very Good (1,004 reviews) "Excellent hotel and great for price" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Mattia $140 nightly $168 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Chilworth-London-Paddington.h901179.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/1766431a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/w2998h2250x2y0-31f0e52c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/93831e6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/b8d3eef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanderson London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) London City Centre 8.8/10 Excellent (1,007 reviews) "Very clean room, excellent friendly staff, all bathroom features worked perfectly," ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LEO $284 nightly $341 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) ![Suite, 1 Bedroom, Terrace | View from room](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/b655f5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/560d2d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/2130619e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/44a7a8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The May Fair, A Radisson Collection Hotel, Mayfair London [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) London City Centre 8.8/10 Excellent (1,006 reviews) "Enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DANIEL $308 nightly $370 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/f03f99a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/666f9324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Premium bedding, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/109743a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/e916b08e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vintry & Mercer Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) London City Centre 9.8/10 Exceptional (1,002 reviews) "Rooms immaculate and super friendly staff" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maxine $220 nightly $264 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/76a121e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/4837b788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/a6226682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4950000/4944700/4944634/02c8af79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ampersand Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) London City Centre 9.6/10 Exceptional (1,005 reviews) "Great hotel & staff, comfortable bed. Really great area" ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Mitchell $206 nightly $247 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Ampersand-Hotel.h4944634.Hotel-Information) ![2 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/890d685c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/2c6ec772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/w3835h2180x0y5-bd7f5066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22500/22478/834f7d03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) London City Centre 8.6/10 Excellent (968 reviews) "Amazing staff, beautiful architecture and excellent restaurant!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jaskiran $151 nightly $181 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-100-Queens-Gate-Hotel-London.h22478.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Isleworth. ![Strand Palace Hotel](https://images.trvl-media.com/lodging/1000000/10000/200/179/6848fd94_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Strand Palace Hotel 372 The Strand London England $157 nightly $189 total Mar 8 - Mar 9 Total with taxes and fees 9/10 Wonderful! (4,996 reviews) [](https://expedia.com/London-Hotels-The-Strand-Palace-Hotel.h179.Hotel-Information) ![The Tower Hotel, by Thistle](https://images.trvl-media.com/lodging/1000000/10000/2500/2479/717976c5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Tower Hotel, by Thistle St Katharine's Way London England $135 nightly $162 total Apr 5 - Apr 6 Total with taxes and fees 8.2/10 Very Good! (9,490 reviews) [](https://expedia.com/London-Hotels-The-Tower-Hotel.h2479.Hotel-Information) ![The Royal Horseguards, London](https://images.trvl-media.com/lodging/1000000/30000/26000/25926/1f40d817_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Royal Horseguards, London 2 Whitehall Court London England $219 nightly $263 total Mar 15 - Mar 16 Total with taxes and fees 9.2/10 Wonderful! (2,171 reviews) [](https://expedia.com/London-Hotels-The-Royal-Horseguards.h25926.Hotel-Information) Still don't see what you're looking for? [See all properties in Isleworth.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=10864&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=10864&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=10864&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=10864&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=10864&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=10864&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Isleworth Tucked along the Thames, this historic riverside town offers peaceful walks past Syon House's magnificent gardens and the charming Old Isleworth pubs. Catch a rugby match at nearby Twickenham Stadium or explore the London Museum of Water and Steam where Victorian pumping engines still operate. [See all hotels in Isleworth](https://www.expedia.com/Hotel-Search?startDate=2026-03-21&endDate=2026-03-22&adults=2®ionId=10864) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=900&h=598&p=1&q=high) Photo by Maxwell Hamilton ## Top Isleworth Hotel Reviews ![Sea Containers London](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637_y.jpg) ### Sea Containers London 10/10 Excellent "Room was clean and cool design! Loved the lighting design and the bed was super comfy. Great cocktails at both bars. Can't beat the location and the views! Will be back. " [](https://expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ![Royal Garden Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58_y.jpg) ### Royal Garden Hotel 6/10 Okay "This hotel located within walking or driving distance most tourist attractions which made it an ideal stay. The staff were friendly and the restaurant was pretty great. " [](https://expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Nobu London Portman Square](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/d00975c1_y.jpg) ### Nobu London Portman Square 8/10 Good "Long wait to check in" [](https://expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) ## Find out more about Isleworth Ready to experience the next standard in luxury? We know you're thinking about it. Add an extra layer of enjoyment on your next trip to Isleworth by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Isleworth any longer. You'll join the multitudes of vacationers who have made Isleworth so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Isleworth and get ready to be pampered like never before. ### Book the Best Isleworth 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you suggest the next attraction to visit? A Swedish massage to help your cares fall away? Fluffy down pillows, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Isleworth are waiting for you to relax after an exciting day. ### Make Your Escape The results are in, and Isleworth 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Isleworth 5-star hotels today and soothe yourself in total tranquility tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Isleworth? ### How much does it cost to stay in a 5-star hotel in Isleworth? > - Search for the lowest price per night from $162 ### What makes a hotel 5 stars in Isleworth? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Isleworth Recreation Centre ](https://www.expedia.com/Isleworth-Recreation-Centre-Hotels.0-l553248621532491841-0.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in St. Margarets and North Twickenham ](https://www.expedia.com/St-Margarets-And-North-Twickenham-London-Hotels-LGBT-Welcoming-Hotel.0-n553248635976382080-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Houseboats in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Houseboats.d553248634668496880-aaHouseboats.Travel-Guide-Accommodation) - [Aparthotels in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Apart-Hotels.d553248634668496880-aaApartHotels.Travel-Guide-Accommodation) - 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