Title: The Best 5 Star Hotels in Isleworth from $161 | Expedia.com [Isleworth Travel Guide](https://expedia.com/Isleworth.dx10864)[Hotels in Isleworth](https://expedia.com/Isleworth-Hotels.d10864.Travel-Guide-Hotels)[Vacation Rentals in Isleworth](https://expedia.com/Isleworth-Vacation-Rentals.d10864.Travel-Guide-VacationRentals)[Flights to Isleworth](https://expedia.com/Cheap-Flights-To-Isleworth.d10864.Travel-Guide-Flights)[Things to do in Isleworth](https://expedia.com/Things-To-Do-In-Isleworth.d10864.Travel-Guide-Activities)[Car Rentals in Isleworth](https://expedia.com/Car-Rentals-In-Isleworth.d10864.Car-Rental-Guide)[Isleworth Vacation Packages](https://expedia.com/Isleworth.d10864.Destination-Travel-Guides) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Maxwell Hamilton ![](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Isleworth 5 Star Hotels Tonight [Mar 4 - Mar 5](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-04&endDate=2026-03-05&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-05&endDate=2026-03-06&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=10864&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Isleworth 5-star hotels ![View from room](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/86ea6f58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/9d683740.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/15070c83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/70dac539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Garden Hotel [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) London City Centre 9.2/10 Wonderful (1,852 reviews) "Lovely stay, will definitely stay again. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Susan $204 nightly $245 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/6026e0f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![English breakfast on weekdays (GBP 20 per person)](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/0447799c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/409fec75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1741000/1740977/f318e22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sofitel London Heathrow [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) Heathrow Villages 8.8/10 Excellent (4,956 reviews) "Convenient location, helpful staff, comfortable room, great food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine $200 nightly $240 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sofitel-London-Heathrow.h1740977.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/d00975c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Japanese cuisine](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/42284ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/988abfd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch, and dinner](https://images.trvl-media.com/lodging/1000000/20000/20000/19959/bd86ccc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nobu London Portman Square [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) London City Centre 9.0/10 Wonderful (455 reviews) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janette $348 nightly $418 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Nobu-London-Portman-Square.h19959.Hotel-Information) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4c05e12f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite | View from room](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/bb16e719.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/4f34d2d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/35000000/34930000/34928100/34928032/87b8b029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Standard London [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) London City Centre 9.2/10 Wonderful (1,678 reviews) "Great hotel. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Greg $258 nightly $310 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Standard-London.h34928032.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar, cocktail bar](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/0d683072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Riverview Studio Suite | Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/1e715d68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/a8f10074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sea Containers London [](https://www.expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) London City Centre 9.4/10 Exceptional (2,407 reviews) "Clean rooms, great location and a fantastic staff. Highly recommend " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Bhavneet $204 nightly $245 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/bda072e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/64960824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (London Eye View) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/96782a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Garden Room | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470900/470865/c5863f8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### St Martins Lane London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) London City Centre 9.4/10 Exceptional (1,007 reviews) "Always a warm welcome and super comfy beds " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) William $302 nightly $362 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-St-Martins-Lane-London.h470865.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/ddf11236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/88a8c12e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/0554ee1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/520000/518100/518026/b80e5543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Royal Lancaster London [](https://www.expedia.com/London-Hotels-Royal-Lancaster-London.h518026.Hotel-Information) London City Centre 9.6/10 Exceptional (1,010 reviews) "Very good location and room exceeded my expectations " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Felix $246 nightly $295 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Royal-Lancaster-London.h518026.Hotel-Information) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/53671bb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/0b506dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; British cuisine ](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/4060269f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/6000000/5930000/5921200/5921175/852c4beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kaya Great Northern Hotel [](https://www.expedia.com/London-Hotels-Kaya-Great-Northern-Hotel.h5921175.Hotel-Information) London City Centre 8.8/10 Excellent (1,002 reviews) "Nice room, clean and well laid out " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Jonathan $240 nightly $288 total Apr 3 - Apr 4 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Kaya-Great-Northern-Hotel.h5921175.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/2fa787ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/3b80b7b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/98bd7043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/61000000/60290000/60280900/60280897/c333d282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Middle Eight - Covent Garden - Preferred Hotels and Resorts [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) London City Centre 9.4/10 Exceptional (1,528 reviews) "we loved everything here and what a great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan $235 nightly $283 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Middle-Eight-Covent-Garden-Preferred-Hotels-And-Resorts.h60280897.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/82f4f487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/80e0da06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, pub, cocktail bar](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/699fc530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/22100/22099/ea1ddd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Langham, London [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) London City Centre 9.6/10 Exceptional (1,004 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) NEIL $531 nightly $637 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Langham.h22099.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5964h3835x0y5-6b0ac613.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/w5755h3835x5y5-b98050e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/1b99c5b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/7700/7613/a3817d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency London The Churchill [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) London City Centre 9.0/10 Wonderful (1,004 reviews) "Location, staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Saad $369 nightly $443 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Hyatt-Regency-London-The-Churchill.h7613.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4270000/4269500/4269455/w4263h3200x0y0-30ae90e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4270000/4269500/4269455/ba2c328b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/5000000/4270000/4269500/4269455/775e997b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/5000000/4270000/4269500/4269455/ff36ffc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montcalm Brewery, London City [](https://www.expedia.com/London-Hotels-The-Montcalm-At-Brewery-London-City.h4269455.Hotel-Information) London City Centre 8.0/10 Very Good (1,005 reviews) "Lovely hotel and absolutely fantastic staff. Superb location for Barbican. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Sam $163 nightly $195 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Montcalm-At-Brewery-London-City.h4269455.Hotel-Information) ![Daily English breakfast (GBP 45 per person)](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/dee77aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Double Room | Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/e8a9d2ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/f30e82e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/528400/528337/9ca37fcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Rubens at the Palace [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) London City Centre 9.2/10 Wonderful (1,009 reviews) "It was very good definitely will be back again! " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Zozan $231 nightly $278 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Rubens-At-The-Palace.h528337.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/a2216a6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/4133b88a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Junior Suite | 1 bedroom, Egyptian cotton sheets, premium bedding, free minibar items](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/ee68fa5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool, free cabanas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/5700/5685/950c8a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Berkeley, Maybourne [](https://www.expedia.com/London-Hotels-The-Berkeley.h5685.Hotel-Information) London City Centre 9.2/10 Wonderful (282 reviews) "Outstanding!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Wesley $800 nightly $961 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Berkeley.h5685.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/ffd90ca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/d66da358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aethos Panorama Suite | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/22be8162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/18000000/17840000/17836300/17836240/dd626e6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aethos Hotel London Shoreditch [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) London City Centre 9.6/10 Exceptional (74 reviews) "great room location restaurant " ![Japan](https://a.travel-assets.com/egds/marks/flags/jp.svg) TOSHIHIKO $249 nightly $299 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Aethos-London-Shoreditch.h17836240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/aab668ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/ef9667ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/f8f85053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/901200/901179/0d6c7c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montcalm Chilworth Townhouse, Paddington [](https://www.expedia.com/London-Hotels-The-Chilworth-London-Paddington.h901179.Hotel-Information) London City Centre 8.0/10 Very Good (1,002 reviews) "Excellent hotel and great for price" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Mattia $134 nightly $161 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Chilworth-London-Paddington.h901179.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/1766431a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/b8d3eef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; garden views](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/93831e6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace Suite | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/480000/470300/470265/273144dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanderson London, a Morgans Originals hotel [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) London City Centre 8.8/10 Excellent (1,005 reviews) "Very clean room, excellent friendly staff, all bathroom features worked perfectly," ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LEO $292 nightly $351 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Sanderson-London.h470265.Hotel-Information) ![Suite, 1 Bedroom, Terrace | View from room](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/b655f5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/560d2d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/44a7a8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Terrace | Living room | Flat-screen TV](https://images.trvl-media.com/lodging/1000000/10000/7700/7606/36d73476.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The May Fair, A Radisson Collection Hotel, Mayfair London [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) London City Centre 8.8/10 Excellent (1,003 reviews) "Enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DANIEL $325 nightly $390 total Apr 2 - Apr 3 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-May-Fair.h7606.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/f03f99a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/90869620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/666f9324.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/20000000/19460000/19458400/19458363/e916b08e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vintry & Mercer Hotel - Small Luxury Hotels of the World [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) London City Centre 9.8/10 Exceptional (1,001 reviews) "Rooms immaculate and super friendly staff" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maxine $221 nightly $265 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/London-Hotels-Vintry-Mercer-Hotel.h19458363.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/3600/3551/c7876ed5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/1000000/10000/3600/3551/296010a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3600/3551/5ed2bce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/10000/3600/3551/db2c3084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Montcalm Piccadilly Townhouse, London West End [](https://www.expedia.com/London-Hotels-The-Piccadilly-London-West-End.h3551.Hotel-Information) London City Centre 8.6/10 Excellent (1,005 reviews) "A great hotel in a fantastic location with exceptional staff ready to help with any query " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Carolyn $181 nightly $217 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/London-Hotels-The-Piccadilly-London-West-End.h3551.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Isleworth-Hotels.s50-0-d10864.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Isleworth. ![Strand Palace Hotel](https://images.trvl-media.com/lodging/1000000/10000/200/179/7dc50d5d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Strand Palace Hotel 372 The Strand London England $158 nightly $190 total Mar 8 - Mar 9 Total with taxes and fees 9/10 Wonderful! (4,971 reviews) [](https://expedia.com/London-Hotels-The-Strand-Palace-Hotel.h179.Hotel-Information) ![The Tower Hotel, by Thistle](https://images.trvl-media.com/lodging/1000000/10000/2500/2479/3f816d92_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Tower Hotel, by Thistle St Katharine's Way London England $138 nightly $166 total Mar 15 - Mar 16 Total with taxes and fees 8.2/10 Very Good! (9,465 reviews) [](https://expedia.com/London-Hotels-The-Tower-Hotel.h2479.Hotel-Information) ![The Royal Horseguards, London](https://images.trvl-media.com/lodging/1000000/30000/26000/25926/79e35abc_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Royal Horseguards, London 2 Whitehall Court London England $263 nightly $315 total Mar 29 - Mar 30 Total with taxes and fees 9/10 Wonderful! (2,160 reviews) [](https://expedia.com/London-Hotels-The-Royal-Horseguards.h25926.Hotel-Information) Still don't see what you're looking for? [See all properties in Isleworth.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026®ionId=10864&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026®ionId=10864&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026®ionId=10864&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026®ionId=10864&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026®ionId=10864&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F5%2F2026&endDate=3%2F6%2F2026®ionId=10864&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Isleworth Tucked along the Thames, this historic riverside town offers peaceful walks past Syon House's magnificent gardens and the charming Old Isleworth pubs. Catch a rugby match at nearby Twickenham Stadium or explore the London Museum of Water and Steam where Victorian pumping engines still operate. [See all hotels in Isleworth](https://www.expedia.com/Hotel-Search?startDate=2026-03-18&endDate=2026-03-19&adults=2®ionId=10864) ![Osterley House, Osterley Park, Middlesex](https://images.trvl-media.com/place/10864/a88bfcbd-4e51-45cc-8e72-75d49f156efa.jpg?impolicy=fcrop&w=900&h=598&p=1&q=high) Photo by Maxwell Hamilton ## Top Isleworth Hotel Reviews ![Sea Containers London](https://images.trvl-media.com/lodging/9000000/8470000/8466300/8466215/68467637_y.jpg) ### Sea Containers London 10/10 Excellent "Beautiful new hotel in a fantastic location on the South Bank - super close to transport options - and really cool, quiet rooms with amazing views over the river and city" [](https://expedia.com/London-Hotels-Sea-Containers-London.h8466215.Hotel-Information) ![Royal Garden Hotel](https://images.trvl-media.com/lodging/1000000/60000/55000/54987/9d683740_y.jpg) ### Royal Garden Hotel 10/10 Excellent "Amazing views of Hyde Park and Kensington Gardens. Room was spacious and comfortable and the bathtub was a real treat after a long day out. Free access to the public Anytime Fitness club was also appreciated. But above all the staff were the icing on the cake - always with smiles and eager to help. " [](https://expedia.com/London-Hotels-Royal-Garden-Hotel.h54987.Hotel-Information) ## Find out more about Isleworth Ready to experience the next standard in luxury? We know you're thinking about it. Add an extra layer of enjoyment on your next trip to Isleworth by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Isleworth any longer. You'll join the multitudes of vacationers who have made Isleworth so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Isleworth and get ready to be pampered like never before. ### Book the Best Isleworth 5-Star Hotels You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you suggest the next attraction to visit? A Swedish massage to help your cares fall away? Fluffy down pillows, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs. Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Isleworth are waiting for you to relax after an exciting day. ### Make Your Escape The results are in, and Isleworth 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Isleworth 5-star hotels today and soothe yourself in total tranquility tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Isleworth? ### How much does it cost to stay in a 5-star hotel in Isleworth? > - Search for the lowest price per night from $166 ### What makes a hotel 5 stars in Isleworth? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Isleworth Recreation Centre ](https://www.expedia.com/Isleworth-Recreation-Centre-Hotels.0-l553248621532491841-0.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in St. Margarets and North Twickenham ](https://www.expedia.com/St-Margarets-And-North-Twickenham-London-Hotels-LGBT-Welcoming-Hotel.0-n553248635976382080-0-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Houseboats in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Houseboats.d553248634668496880-aaHouseboats.Travel-Guide-Accommodation) - [Aparthotels in Isleworth Station ](https://www.expedia.com/Isleworth-Station-Apart-Hotels.d553248634668496880-aaApartHotels.Travel-Guide-Accommodation) - 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