Title: 15 Best Cabins in East Prairie, MO - Cabins for Rent from $248 | Expedia.com

[East Prairie Travel Guide](https://expedia.com/East-Prairie.dx3000349349)[Hotels in East Prairie](https://expedia.com/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels)[Vacation Rentals in East Prairie](https://expedia.com/East-Prairie-Vacation-Rentals.d3000349349.Travel-Guide-VacationRentals)[Car Rentals in East Prairie](https://expedia.com/Car-Rentals-In-East-Prairie.d3000349349.Car-Rental-Guide)[East Prairie Vacation Packages](https://expedia.com/East-Prairie.d3000349349.Destination-Travel-Guides)

![The Mississippi River near Hannibal, Missouri, USA](https://images.trvl-media.com/place/6209928/2afb9a4b-494b-462a-af23-159cb6a96bb2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for East Prairie cabin rentals

![Smart TV](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/0d61a825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/342c28ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/5fe9a626.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101880000/101879200/101879138/98a7dc87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Tiptonville

[](https://www.expedia.com/Tiptonville-Hotels-Tiny-House-On-The-Lake-With-A-Seventy-Five-Inch-T-V-Free-Internet-Walk-Shower.h101879138.Hotel-Information)

10/10

Exceptional

(1 review)

"Dave was very accommodating and the home was clean."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Katherine P.

$219 nightly

$248 total

Mar 7 - Mar 8

Total with taxes and fees

[](https://www.expedia.com/Tiptonville-Hotels-Tiny-House-On-The-Lake-With-A-Seventy-Five-Inch-T-V-Free-Internet-Walk-Shower.h101879138.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-20&endDate=2026-03-21&regionId=3000349349&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cottages

[](https://www.expedia.com/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=COTTAGE)

Cabins

[](https://www.expedia.com/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=VACATION_HOME)

Condos

[](https://www.expedia.com/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=CONDO)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=East+Prairie%2C+Missouri%2C+United+States+of+America&regionId=3000349349&latLong=36.779778%2C-89.38563&adults=2&startDate=2026-06-03&d1=2026-06-03&endDate=2026-06-06&d2=2026-06-06&lodging=APARTMENT)

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## Top East Prairie Hotel Reviews

![Hampton Inn Union City](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f7d6d20c_y.jpg)

### Hampton Inn Union City

10/10 Excellent

"It was a clean property with a normal breakfast that I expect from Hampton Inn (which is overall pleasant). I had no problems and the kids enjoyed the pool. I was pleasantly surprised with the gym equipment for a hotel."

[](https://expedia.com/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information)

![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7_y.jpg)

### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

10/10 Excellent

"The room was clean and comfortable. Check in staff was friendly. "

[](https://expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information)

![Quality Inn Union City US 51](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/c1609da5_y.jpg)

### Quality Inn Union City US 51

8/10 Good

"All was pretty good except for the breakfast."

[](https://expedia.com/Union-City-Hotels-Quality-Inn-Union-City-US-51.h14571.Hotel-Information)

![Sleep Inn at Discovery Park of America](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0_y.jpg)

### Sleep Inn at Discovery Park of America

10/10 Excellent

"Easy to find, ample parking, in a private location so able to walk outside. Room was clean and comfortable. Breakfast was good."

[](https://expedia.com/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information)

![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg)

### Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Plenty of good parking. Good food choices nearby. Very comfortable rooms"

[](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information)

![Country Yard Inn and Suite](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a_y.jpg)

### Country Yard Inn and Suite

10/10 Excellent

"I love this hotel."

[](https://expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information)

![Best Western Plus Sikeston I-55](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg)

### Best Western Plus Sikeston I-55

4/10 Poor

"We started our stay with a hostile guest while trying to check in. The lack of care from the worker at check in was a new level of IDGAF, the following day they turned our"

[](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information)

![Reelfoot Lake Inn](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/543bd231_y.jpg)

### Reelfoot Lake Inn

10/10 Excellent

"Everything great "

[](https://expedia.com/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information)

![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg)

### Hampton Inn Sikeston

8/10 Good

"Good room and helpful staff"

[](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information)

## Find out more about East Prairie

## East Prairie Cabin Rentals information

| Number of reviews | 1               |
| ----------------- | --------------- |
| Accommodation     | 3 Cabin Rentals |
| Lowest Price      | $248            |
| Highest Price     | $248            |

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