Title: Best Apartments in Charleston, MO for Your Vacation from $162 | Expedia.com [Charleston Travel Guide](https://expedia.com/Charleston.dx7182)[Hotels in Charleston](https://expedia.com/Charleston-Hotels.d7182.Travel-Guide-Hotels)[Vacation Rentals in Charleston](https://expedia.com/Charleston-Vacation-Rentals.d7182.Travel-Guide-VacationRentals)[Flights to Charleston](https://expedia.com/Cheap-Flights-To-Charleston.d7182.Travel-Guide-Flights)[Car Rentals in Charleston](https://expedia.com/Car-Rentals-In-Charleston.d7182.Car-Rental-Guide)[Charleston Vacation Packages](https://expedia.com/Charleston.d7182.Destination-Travel-Guides) ![Cypress Trees on the Horizon. A sting of cypress trees of various sizes extend across the horizon as the sunken sun paints the multicolored sky. ](https://images.trvl-media.com/place/7182/2c4b1a06-d3aa-4171-b8b6-0e4eaaa0e80e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7182/2c4b1a06-d3aa-4171-b8b6-0e4eaaa0e80e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=7182&startDate=2026-03-27&endDate=2026-03-29&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=7182&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=7182&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 3 - Jul 5](https://www.expedia.com/Hotel-Search?regionId=7182&startDate=2026-07-03&endDate=2026-07-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Charleston apartments ![Smart TV](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/3df6bc42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/4d3b20d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/93527246.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122910000/122905300/122905281/f9ad8a19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquil charming Tiny House in Clinton [](https://www.expedia.com/Clinton-Hotels-Tranquil-Charming-Tiny-House-In-Clinton.h122905281.Hotel-Information) Clinton 10/10 Exceptional (1 review) "Super clean and comfortable. We were in the area visiting family and were so happy to find this rental. Very clean, comfortable beds, great sheets and towels. Thank you Zack and Tiff for opening your cute little rental to us. We hope you’re not booked when we return. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura K. $136 nightly $145 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Clinton-Hotels-Tranquil-Charming-Tiny-House-In-Clinton.h122905281.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/123000000/122500000/122496300/122496264/f77528b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/123000000/122500000/122496300/122496264/6f5a5a28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122500000/122496300/122496264/0181be39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/123000000/122500000/122496300/122496264/3b2e432e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vacation rental attached to our house out in the country. [](https://www.expedia.com/Union-City-Hotels-Vacation-Rental-Attached-To-Our-House-Out-In-The-Country.h122496264.Hotel-Information) Union City 10/10 Exceptional (1 review) "Nice place. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew E. $145 nightly $162 total Mar 10 - Mar 11 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Vacation-Rental-Attached-To-Our-House-Out-In-The-Country.h122496264.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-23&endDate=2026-03-24®ionId=7182&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=AA_SPRING_PROMO_7182) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Charleston%2C+Missouri%2C+United+States+of+America®ionId=7182&latLong=36.923187%2C-89.349998&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=CABIN) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Charleston%2C+Missouri%2C+United+States+of+America®ionId=7182&latLong=36.923187%2C-89.349998&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=VACATION_HOME) Cottages [](https://www.expedia.com/Hotel-Search?destination=Charleston%2C+Missouri%2C+United+States+of+America®ionId=7182&latLong=36.923187%2C-89.349998&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=COTTAGE) Apartments [](https://www.expedia.com/Hotel-Search?destination=Charleston%2C+Missouri%2C+United+States+of+America®ionId=7182&latLong=36.923187%2C-89.349998&adults=2&startDate=2026-06-07&d1=2026-06-07&endDate=2026-06-10&d2=2026-06-10&lodging=APARTMENT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCharleston-Apartments.d7182-aaApartments.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCharleston-Apartments.d7182-aaApartments.Travel-Guide-Accommodation) ## Top Charleston Hotel Reviews ![Best Western Plus Sikeston I-55](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston I-55 10/10 Excellent "All Ol" [](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Overall our stay was great with the exception of the room smelling like a dog had been living there. The order was in the carpet and the bed covers. " [](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "This hotel is awesome the breakfast and supper meals are awesome everything with this hotel is awesome " [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/8bb15ffe_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "Really nice hotel that is convenient to Interstate 55\. That said, request a room away from the highway side of the building to muffle sounds of cars zooming by. " [](https://expedia.com/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Lovely property. I don’t gamble, but if you do, it’s clearly convenient to the casino. Comfortable bed, very clean room, lovely staff" [](https://expedia.com/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/6966efed_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Great experience. We will pick Drury every time we travel. " [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/5929e46c_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "Clean room , nice staff" [](https://expedia.com/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 8/10 Good "Very clean but sometimes noisy from outside traffic" [](https://expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Courtyard by Marriott Cape Girardeau Downtown](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718_y.jpg) ### Courtyard by Marriott Cape Girardeau Downtown 10/10 Excellent "The bed was so comfortable. Everything was very clean. Location was right in downtown so it was very convenient." [](https://expedia.com/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ## Find out more about Charleston ## Charleston Apartments information | Number of reviews | 1 | | ----------------- | ------------- | | Accommodation | 11 Apartments | | Lowest Price | $162 | | Highest Price | $162 | ## Frequently asked questions ### What's it like to stay at an apartment in Charleston? ### How do you know if an apartment is a good option for your stay? ### What's a favorite apartment for my stay in Charleston? ### What can I expect from the weather during my trip to Charleston? ### What should I see and do in Charleston? ### What's the best way to get to and around Charleston? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Diehlstadt Hotels ](https://www.expedia.com/Diehlstadt-Hotels.d553248634983544913.Travel-Guide-Hotels) - [Motels in Bertrand ](https://www.expedia.com/Bertrand-Motels.d3000349285-aaMotels.Travel-Guide-Accommodation) - 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