Photo by Hazem Abdul

Find 4 Star Hotels in South Main, TX from $105

Start date: Check-in selected.
To Date
End date: Check-out

    Upfront pricing

    Our total price for your stay includes taxes and fees

    Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

    Be picky

    Search almost a million properties worldwide

Check availability on South Main 4 Star Hotels

Compare South Main 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Exterior detail
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
4.0 star property
8.2 out of 10, Very Good, (2700)
"We had a wonderful stay"
$123 nightly
The price is $144
Oct 30 - Oct 31
Total with taxes and fees
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Lobby
Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
4.0 star property
8.4 out of 10, Very Good, (3787)
"Lovely place to STAY’nm"
$110 nightly
The price is $129
Nov 17 - Nov 18
Total with taxes and fees
Club Quarters Hotel Downtown, Houston
1 bedroom, premium bedding, pillowtop beds, minibar
Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum District
4.5 star property
9.0 out of 10, Wonderful, (1798)
"Best place I have stayed in decades."
$278 nightly
The price is $326
Nov 16 - Nov 17
Total with taxes and fees
Hotel Zaza Houston Museum District
Sundeck
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
4.5 star property
8.4 out of 10, Very Good, (1640)
"Amazing stay "
$90 nightly
The price is $105
Oct 19 - Oct 20
Total with taxes and fees
Hilton Houston Plaza/Medical Center
Business center
DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway Plaza
4.0 star property
8.2 out of 10, Very Good, (1249)
"Enjoyed my stay. Room was nice - location great."
$109 nightly
The price is $128
Oct 19 - Oct 20
Total with taxes and fees
DoubleTree by Hilton Hotel Houston - Greenway Plaza
View from property
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Magnolia Hotel Houston, A Tribute Portfolio Hotel
4.0 star property
9.2 out of 10, Wonderful, (1204)
"I enjoyed my stay. Love this hotel."
$162 nightly
The price is $189
Oct 19 - Oct 20
Total with taxes and fees
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Interior
Omni Houston Hotel
Omni Houston Hotel
4.0 star property
9.0 out of 10, Wonderful, (1017)
"Really enjoyed my stay. "
$182 nightly
The price is $213
Nov 16 - Nov 17
Total with taxes and fees
Omni Houston Hotel
Lunch, dinner, brunch served; Italian cuisine
C. Baldwin, Curio Collection by Hilton
C. Baldwin, Curio Collection by Hilton
4.0 star property
8.4 out of 10, Very Good, (1013)
"Gorgeous hotel and great staff!"
$169 nightly
The price is $198
Nov 1 - Nov 2
Total with taxes and fees
C. Baldwin, Curio Collection by Hilton
Front of property
Blossom Hotel Houston, Curio Collection by Hilton
Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
9.0 out of 10, Wonderful, (3561)
"Great stay "
$132 nightly
The price is $154
Nov 16 - Nov 17
Total with taxes and fees
Blossom Hotel Houston, Curio Collection by Hilton
City view from property
The Whitehall Houston
The Whitehall Houston
4.0 star property
8.6 out of 10, Excellent, (1801)
"Great staff nice rooms"
$143 nightly
The price is $167
Nov 2 - Nov 3
Total with taxes and fees
The Whitehall Houston
Exterior
The Royal Sonesta Houston Galleria
The Royal Sonesta Houston Galleria
4.0 star property
8.4 out of 10, Very Good, (1294)
"Great hotel "
$129 nightly
The price is $151
Oct 31 - Nov 1
Total with taxes and fees
The Royal Sonesta Houston Galleria
Outdoor pool, open 6:00 AM to 10:00 PM, pool umbrellas, sun loungers
Hyatt Regency Houston/Galleria
Hyatt Regency Houston/Galleria
4.0 star property
9.0 out of 10, Wonderful, (1101)
"Wonderful property!!! Very much enjoyed our stay! "
$159 nightly
The price is $186
Nov 2 - Nov 3
Total with taxes and fees
Hyatt Regency Houston/Galleria
Exterior
Hilton Americas-Houston
Hilton Americas-Houston
4.0 star property
9.4 out of 10, Exceptional, (1530)
"Clean, friendly atmosphere enjoyed the buffet, and the servers was a great getaway"
$188 nightly
The price is $220
Oct 24 - Oct 25
Total with taxes and fees
Hilton Americas-Houston
Cocktail bar
Le Meridien Houston Downtown
Le Meridien Houston Downtown
4.0 star property
8.8 out of 10, Excellent, (1023)
"Everything was perfect with our stay. "
$142 nightly
The price is $166
Oct 23 - Oct 24
Total with taxes and fees
Le Meridien Houston Downtown
Banquet hall
The Westin Galleria Houston
The Westin Galleria Houston
4.5 star property
9.0 out of 10, Wonderful, (1002)
"Greatly located in the Houston Galleria Mall. The staff is kind and responsive. Food is good for room service."
$209 nightly
The price is $245
Oct 24 - Oct 25
Total with taxes and fees
The Westin Galleria Houston
Lobby
Thompson Houston, by Hyatt
Thompson Houston, by Hyatt
4.0 star property
9.2 out of 10, Wonderful, (210)
"Loved our stay here. Super close to so many great restaurants. The property and pool were gorgeous and the staff were all so friendly. Would 100% stay here again."
$326 nightly
The price is $381
Oct 19 - Oct 20
Total with taxes and fees
Thompson Houston, by Hyatt
Exterior
The Moran CITYCENTRE
The Moran CITYCENTRE
4.0 star property
9.0 out of 10, Wonderful, (1015)
"Great place to stay."
$203 nightly
The price is $237
Nov 1 - Nov 2
Total with taxes and fees
The Moran CITYCENTRE
Reception
InterContinental Houston by IHG
InterContinental Houston by IHG
4.0 star property
9.2 out of 10, Wonderful, (1014)
"I love this property everytime i stay here"
$152 nightly
The price is $178
Oct 18 - Oct 19
Total with taxes and fees
InterContinental Houston by IHG
Lobby
Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum District
4.0 star property
9.0 out of 10, Wonderful, (1005)
"Property was very clean and safe was very friendly."
$205 nightly
The price is $240
Oct 18 - Oct 19
Total with taxes and fees
Houston Marriott Medical Center/Museum District
Exterior
Houston Marriott Westchase
Houston Marriott Westchase
4.0 star property
8.2 out of 10, Very Good, (1018)
"Enjoyed our stay at this location."
$112 nightly
The price is $131
Oct 31 - Nov 1
Total with taxes and fees
Houston Marriott Westchase
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in South Main.
The Post Oak Hotel at Uptown Houston

The Post Oak Hotel at Uptown Houston

1600 West Loop South, Houston, TX
$489 nightly
The price is $573 total per night from Nov 17 to Nov 18
$573 total
Nov 17 - Nov 18
Total with taxes and fees
9.6/10 Exceptional! (836 reviews)
Still don't see what you're looking for?
See all properties in South Main.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top South Main Hotel Reviews

Omni Houston Hotel

Omni Houston Hotel

10/10 Excellent
"Awesome check in staff and valet. Wonderful bar manager who made an excellent lemon drop martini."
Amy 1-night trip
Posted 14 hours ago
Omni Houston Hotel

Explore a world of travel with Expedia