A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find 4 Star Hotels in St. Louis, MO from $132

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis 4 Star Hotels

Tonight
Oct 16 - Oct 17
Tomorrow
Oct 17 - Oct 18
This weekend
Oct 16 - Oct 18
Next weekend
Oct 23 - Oct 25

Our top choices for St. Louis 4-star hotels

A buffet with fruits, pastries, and beverages.
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.
The Renaissance Hotel with a modern architectural design, featuring a prominent central entrance and a symmetrical facade.
A modern bar area with a long counter, white bar stools, and a mix of bar and dining tables.

1. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
Berkeley
United States
Anthony
$118 nightly
$138 total
Nov 15 - Nov 16
Total with taxes and fees
Renaissance St. Louis Airport Hotel
A lobby with a sofa, two armchairs, a coffee table, and a staircase.
A modern hotel room with a large window, a flat-screen TV mounted on the wall, a round dining table with chairs, and a patterned rug.
A spacious lobby with a sectional sofa, a white armchair, and a glass coffee table. There is a dining area in the background with a chandelier.
A rooftop lounge with large windows, red seating, and a view of the cityscape.

2. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
United States
Johnny
$134 nightly
$158 total
Oct 30 - Oct 31
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A reception desk with a wooden finish and the name "IDOL WOLF" on it.

3. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
United States
Zane
$148 nightly
$173 total
Nov 15 - Nov 16
Total with taxes and fees
21C Museum Hotel St Louis
A cozy lounge area with leather sofas, a fireplace, and a bar counter.
An outdoor patio area with a pool, red umbrellas, and seating arrangements.
A traditional building with a stone facade, large windows, and outdoor seating area with wicker furniture.
A restaurant with a central bar area, seating arrangements, and a fireplace.

4. The Cheshire

The Cheshire
Richmond Heights
United States
Matthew
$148 nightly
$176 total
Oct 25 - Oct 26
Total with taxes and fees
The Cheshire
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.
A restaurant with tables set for dining, a kitchen in the background, and hanging light fixtures.
A modern bar area with a central fire feature, bar stools, and seating.
The exterior of the Clark & Bourbon hotel with a well-lit entrance, a marquee sign, and a landscaped planter area.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
Downtown St. Louis
United States
Molly
$139 nightly
$165 total
Nov 15 - Nov 16
Total with taxes and fees
Live by Loews - St.Louis
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.
A modern restaurant interior with high tables, chairs, and a central bar area.
A bar area with wooden paneling, a counter, and multiple stools.
A modern living room with a grey sofa, a round wooden coffee table, and a large window with a city view.

6. The Westin St. Louis

The Westin St. Louis
Downtown St. Louis
United States
Stacy
$131 nightly
$153 total
Nov 15 - Nov 16
Total with taxes and fees
The Westin St. Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A restaurant with multiple dining tables and chairs, a bar area with shelves of bottles, and a large mirror above the bar.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
United States
Kristina
$186 nightly
$219 total
Nov 15 - Nov 16
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis
A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.
A large hotel with a prominent "RIVER CITY" sign.
A luxurious hotel lobby with a grand stage, elegant seating, and a large chandelier.
A casino with multiple gaming tables and slot machines.

8. River City Casino & Hotel

River City Casino & Hotel
St. Louis
United States
jodi
$116 nightly
$136 total
Oct 27 - Oct 28
Total with taxes and fees
River City Casino & Hotel
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
A modern hotel room with a large window, a bathtub, and a unique eye-themed pillow.
A multi-story hotel with a classic architectural style, featuring a prominent entrance and a series of uniformly lit windows.
A woman sitting on a green sofa in a modern lobby with a staircase and a large framed artwork on the wall.

9. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
United States
Skylee
$126 nightly
$149 total
Oct 21 - Oct 22
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bakery display case with various pastries and cakes.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A grand lobby with a central chandelier, multiple levels, and rows of liquor bottles.

10. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
United States
Melissa
$166 nightly
$195 total
Nov 17 - Nov 18
Total with taxes and fees
Ameristar Casino Resort and Spa
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.
A spacious lobby with a high ceiling, a bar area, multiple seating arrangements, and a large screen displaying a sports event.
Lobby
A spacious interior with a central staircase, large windows, and hanging chandeliers.

11. Marriott St. Louis Grand

Marriott St. Louis Grand
Downtown St. Louis
United States
Andrew
$152 nightly
$181 total
Oct 30 - Oct 31
Total with taxes and fees
Marriott St. Louis Grand
A rooftop restaurant with round tables, chairs, and a view of the city.
A rooftop terrace with seating areas, a decorative moon sculpture, and string lights.
A hotel with a prominent sign reading "MOONRISE."
A modern lobby with a staircase, seating area, and an exit sign.

12. Moonrise Hotel

Moonrise Hotel
Delmar Loop
United States
Jessie
$161 nightly
$192 total
Nov 16 - Nov 17
Total with taxes and fees
Moonrise Hotel
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
A spa bath with a sign indicating a capacity of 8 persons.
A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

13. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
United States
Janell
$128 nightly
$152 total
Nov 15 - Nov 16
Total with taxes and fees
Drury Plaza Hotel St. Louis Brentwood
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.
A spacious lobby with striped chairs, a central coffee table, and large potted plants.
A buffet area with various food items and a self-service station.
An indoor swimming pool area with lounge chairs, a small table, and potted plants.

14. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
Downtown St. Louis
United Kingdom
Luke
$118 nightly
$141 total
Oct 26 - Oct 27
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
A modern hotel room with a large dining table, comfortable seating, a sofa, and a television.
A hotel room with a bed, a sofa, a red ottoman, a nightstand, a lamp, and a view of a cityscape through large windows.
A modern kitchen with a central island, bar stools, and a long dining table.
A modern lounge area with a central fire feature, seating, and large windows offering a city view.

15. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
Downtown St. Louis
United States
kristen
$147 nightly
$175 total
Oct 28 - Oct 29
Total with taxes and fees
Hilton St. Louis at the Ballpark
A brick building with a tower, large windows, and a fountain in the garden.
A pool area with lounge chairs and umbrellas, a clear blue pool, and a building with a dome in the background.
A grand staircase with a curved design, leading to an upper floor.
A spacious lobby with a chandelier, seating area, and a central table with a vase of flowers.

16. Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
Frontenac
United States
Linda L
$130 nightly
$152 total
Oct 25 - Oct 26
Total with taxes and fees
Hilton St. Louis Frontenac
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.
A long dining table set with candles, glassware, and white flowers, suggesting a formal dining experience.
An outdoor seating area with modern furniture, a metal railing, and a view of surrounding buildings.
A bar area with a round table, ice-filled glasses, bottles of champagne, and decorative plants.

17. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
Clayton
United States
Marsha
$152 nightly
$179 total
Oct 25 - Oct 26
Total with taxes and fees
Le Méridien St. Louis Clayton
A modern dining area with round tables, orange chairs, and a decorative wall with pottery.
A Marriott hotel with a large building, multiple flags, and a well-lit entrance area.
A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.
A modern lobby with seating areas, a reception desk, and a bar area.

18. Marriott St. Louis Airport

Marriott St. Louis Airport
Edmundson
United States
Sha
$143 nightly
$172 total
Oct 30 - Oct 31
Total with taxes and fees
Marriott St. Louis Airport
A bar area with a central bar, multiple stools, and a chandelier.
A spacious lobby with a high ceiling, ornate chandeliers, and a seating area with sofas and armchairs.
A grand lobby with a large chandelier, a bar area, and classical architecture.
A grand lobby with a bar area, ornate chandeliers, and a staircase.

19. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
United States
Carol
$111 nightly
$132 total
Oct 30 - Oct 31
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
A spacious lobby with high arched ceilings, ornate columns, and a central fountain.
A spacious lobby with a high arched ceiling, multiple seating areas, and a central decorative column.
A spacious lobby with high ceilings, ornate green and gold detailing, and a central bar area.
A multi-level hotel lobby with a grand staircase, a reception desk, and a seating area.

20. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
Downtown West
United States
Maryann
$163 nightly
$194 total
Oct 30 - Oct 31
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Louis.
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO
$375 nightly
$438 total
Oct 25 - Oct 26
Total with taxes and fees
9.4/10 Exceptional! (1,000 reviews)
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO
$579 nightly
$676 total
Nov 1 - Nov 2
Total with taxes and fees
9.2/10 Wonderful! (586 reviews)
The Ritz-Carlton, St. Louis
Still don't see what you're looking for?
See all properties in St. Louis.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis and related destinations

The Gateway Arch towers 630 feet above the Mississippi, with a tram that takes you to spectacular views at the top. Explore Forest Park's free museums, catch a Cardinals game at Busch Stadium, and don't miss Ted Drewes' frozen custard that locals swear by.

See all hotels in St. Louis
A large white building with a dome and a statue in front, surrounded by fountains and trees.

Top St. Louis Hotel Reviews

Moonrise Hotel

Moonrise Hotel

8/10 Good
"Really cute hotel in Delmar Loop. Fun, quirky style. Excellent location, but our room smelled like wet dog."
Elina 1-night trip
Posted 2 hours ago
Moonrise Hotel
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent
"Parking easy and gated, a little expensive but convenient. Two entrances, easy access to Grand for The Fox or symphony. Elevators were a little confusing at first. Roof Top bar was great. We did not get food but a lot of people did. Beautiful city view day and night. Lots of beautiful, interesting art. I was looking forward to the matching bedding and Eye pillows but they were not there...."
Laura 1-night trip
Posted 8 hours ago
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Live by Loews - St.Louis

Live by Loews - St.Louis

10/10 Excellent
"Staff were very helpful and friendly.."
shelley 1-night trip
Posted 1 day ago
Live by Loews - St.Louis

Price trends for properties with 4 Stars in St. Louis

Less expensive
More expensive
Next month
January
May
$194
Month
Price
January
$159
February
$179
March
$203
April
$204
May
$221
June
$166
July
$174
August
$169
September
$191
October
$175
November
$194
December
$166
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed properties with 4 stars in St. Louis. Select dates and complete search for nightly totals inclusive of taxes and fees.

Find out more about St. Louis

The outset of any much-needed trip kicks off with selecting a location. St. Louis has been a popular option with guests because of everything it offers. Yet, "location, location, location" applies to more than just your vacation destination. Now that you have gotten a feel for St. Louis, it is time you to learn a little more about your residence for the next few nights.

Accommodations as Picturesque as St. Louis

St. Louis saw hundreds of visitors just last year, and our comment section includes tips and tricks to help you select which room is ideal for your holiday. When you reserve a 4-star hotel you can rest easy knowing that these properties are designed to fulfill your needs. These hotels strive to make the facilities and grounds inviting from the moment you step out of your car. You won't have to search for an energizing plunge, delectable dinner, or to sustain your workout schedule during your stay with all that they offer. St. Louis has hundreds of fantastic lodgings that provide the ideal holiday.

Rooms have been furnished to keep you as comfortable as possible, with amenities like designer bathroom products, ultra-comfortable bedding, and in-room tea or coffee. So, lay back and relax. Moreover, if you find yourself in need of something else, you can trust the staff will try their hardest to ensure you stay satisfied during your stay there. These properties are so nice that you'll regret the day you have to fly back home.

Reserve a 4-Star Hotel in St. Louis Today!

Your trip to St. Louis should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are nothing but fabulous. Thanks to Expedia's comment section and information about each accommodation, you can easily select the right hotel for your next holiday to The Gateway to the West.

Frequently asked questions

What are the best 4-star hotels in St. Louis?
Kick back in 4-star hotel comfort at St. Louis Union Station Hotel, Curio Collection by Hilton. Rated highly by many Expedia guests, it offers premium bedding and concierge services. Also consider The Last Hotel. A swimming pool and a pillowtop mattress make this escape another leading pick in St. Louis.
How much does it cost to stay in a 4-star hotel in St. Louis?
We can help you easily find the ideal 4-star hotel for your trip to St. Louis. Use our filter tool to tailor your search by things like price, conveniences and property star rating and get access to fantastic deals in a couple of clicks.
  • Search for the lowest price from $438
What's the difference between 5-star and 4-star hotels in St. Louis?
Offering a welcoming guest experience and upmarket décor, 4-star hotels are a great option for your St. Louis vacation. These kinds of accommodations generally feature loads of handy amenities that make it easy to unpack and recharge — think complimentary bathrobes, pools and restaurants. Or enjoy even more lavishness at a 5-star hotel designed to spoil you with exclusive perks and amenities. Round-the-clock concierge service, complimentary toiletries and gourmet dining are typically featured at these deluxe properties.

Explore a world of travel with Expedia