Find 4 Star Hotels in St. Louis, MO from $102

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Nov 9 - Nov 10
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Nov 10 - Nov 11
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

Our top choices for St. Louis 4-star hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

1. Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,400 reviews)
"Great location and great place to visit"
United States
Tracy
$113 nightly
The price is $133
Nov 27 - Nov 28
Total with taxes and fees
Hyatt Regency St. Louis at The Arch
A modern lobby with a large glass sphere, seating areas, and a reception desk.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (2,148 reviews)
"Wonderful Stay!"
United States
A.R.
$147 nightly
The price is $172
Nov 15 - Nov 16
Total with taxes and fees
21C Museum Hotel St Louis
A spacious hotel lobby with multiple seating areas, a reception desk, and large windows offering a view of the cityscape.

3. Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very good, (1,199 reviews)
"Great Hotel."
United States
Joy
$111 nightly
The price is $130
Nov 27 - Nov 28
Total with taxes and fees
Renaissance St. Louis Airport Hotel
A modern lobby with a staircase, seating area, and wall-mounted artwork.

4. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,054 reviews)
"Cool hotel!"
United States
Rebecca
$149 nightly
The price is $177
Nov 18 - Nov 19
Total with taxes and fees
Moonrise Hotel
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

5. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,363 reviews)
"Great place to stay."
United States
brandon
$139 nightly
The price is $165
Nov 15 - Nov 16
Total with taxes and fees
Live by Loews - St.Louis
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,094 reviews)
"Very nice hotel, lots of amenities, and restaurants"
United States
Carter
$193 nightly
The price is $226
Nov 16 - Nov 17
Total with taxes and fees
Ameristar Casino Resort and Spa
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

7. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.2 out of 10, Wonderful, (1,006 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
$174 nightly
The price is $205
Nov 22 - Nov 23
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

8. Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (802 reviews)
"Beautiful hotel in a convenient location."
United States
Marsha
$152 nightly
The price is $179
Nov 29 - Nov 30
Total with taxes and fees
Le Méridien St. Louis Clayton
A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

9. The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,004 reviews)
"Amazing property, staff was very friendly, great location!!"
United States
Stacy
$122 nightly
The price is $143
Nov 15 - Nov 16
Total with taxes and fees
The Westin St. Louis
A modern hotel lobby with a bar area, seating arrangements, and decorative lighting.

10. Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very good, (1,004 reviews)
"Was a great stay"
United States
Loney
$132 nightly
The price is $159
Nov 20 - Nov 21
Total with taxes and fees
Marriott St. Louis Airport
A spacious lobby with a high ceiling, a central chandelier, and a patterned floor.

11. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,841 reviews)
"Great accommodations - highly recommend"
United States
jodi
$87 nightly
The price is $102
Dec 9 - Dec 10
Total with taxes and fees
River City Casino & Hotel
A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

12. Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.4 out of 10, Very good, (1,005 reviews)
"This was the best hotel we've ever stayed at in St. Louis. It was walking distance from the dome with convenient parking."
United States
Laura
$127 nightly
The price is $151
Nov 22 - Nov 23
Total with taxes and fees
Marriott St. Louis Grand
A grand lobby with a large chandelier, a bar area, and classical architecture.

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,409 reviews)
"Gorgeous historic hotel close to all main downtown sightseeings."
United States
Anastasia
$95 nightly
The price is $113
Nov 23 - Nov 24
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

14. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,010 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
$128 nightly
The price is $152
Nov 22 - Nov 23
Total with taxes and fees
Drury Plaza Hotel St. Louis Brentwood
A grand building with a fountain in front.

15. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,004 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
$149 nightly
The price is $177
Nov 29 - Nov 30
Total with taxes and fees
The Cheshire
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
9.0 out of 10, Wonderful, (1,370 reviews)
"Loved our stay!"
United States
Megan
$105 nightly
The price is $125
Dec 10 - Dec 11
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,173 reviews)
"Loved the hotel!"
United States
Stephanie
$103 nightly
The price is $122
Nov 22 - Nov 23
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
A modern lounge area with a central fire feature, seating, and large windows offering a city view.

18. Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,289 reviews)
"AMAZING STAY! AMAZING VIEWS FEOM ROOFTOP BAR!"
United States
Kella
$139 nightly
The price is $165
Nov 22 - Nov 23
Total with taxes and fees
Hilton St. Louis at the Ballpark
A spacious lobby with high ceilings, ornate columns, and a blue patterned carpet.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.8 out of 10, Excellent, (1,003 reviews)
"Front desk staff was very helpful in answering question about the property and surrounding area!"
United States
William
$155 nightly
The price is $184
Nov 22 - Nov 23
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton
A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.

20. Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,162 reviews)
"I enjoyed my stay and parking was safe."
United States
Jacqueline
$110 nightly
The price is $128
Nov 15 - Nov 16
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch

Top St. Louis Hotel Reviews

An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.
Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood

10/10 Excellent

Breakfast was very good and evening food was good as well! The coffee downstairs is delicious.
United States
Lisa
Reviewed April 6, 2025
Drury Plaza Hotel St. Louis Brentwood

Find out more about St. Louis

The outset of any much-needed trip kicks off with selecting a location. St. Louis has been a popular option with guests because of everything it offers. Yet, "location, location, location" applies to more than just your vacation destination. Now that you have gotten a feel for St. Louis, it is time you to learn a little more about your residence for the next few nights.

Accommodations as Picturesque as St. Louis

St. Louis saw hundreds of visitors just last year, and our comment section includes tips and tricks to help you select which room is ideal for your holiday. When you reserve a 4-star hotel you can rest easy knowing that these properties are designed to fulfill your needs. These hotels strive to make the facilities and grounds inviting from the moment you step out of your car. You won't have to search for an energizing plunge, delectable dinner, or to sustain your workout schedule during your stay with all that they offer. St. Louis has hundreds of fantastic lodgings that provide the ideal holiday.

Rooms have been furnished to keep you as comfortable as possible, with amenities like designer bathroom products, ultra-comfortable bedding, and in-room tea or coffee. So, lay back and relax. Moreover, if you find yourself in need of something else, you can trust the staff will try their hardest to ensure you stay satisfied during your stay there. These properties are so nice that you'll regret the day you have to fly back home.

Reserve a 4-Star Hotel in St. Louis Today!

Your trip to St. Louis should be one that you'll recollect for years to come, and booking a 4-star hotel can help create memories that are nothing but fabulous. Thanks to Expedia's comment section and information about each accommodation, you can easily select the right hotel for your next holiday to The Gateway to the West.

Frequently Asked Questions

What are the best 4-star hotels in St. Louis?

Kick back in 4-star hotel comfort at St. Louis Union Station Hotel, Curio Collection by Hilton. Rated highly by many Expedia guests, it offers premium bedding and concierge services. Also consider The Last Hotel . A swimming pool and a pillowtop mattress make this escape another leading pick in St. Louis.

How much does it cost to stay in a 4-star hotel in St. Louis?

We can help you easily find the ideal 4-star hotel for your trip to St. Louis. Use our filter tool to tailor your search by things like price, conveniences and property star rating and get access to fantastic deals in a couple of clicks.

  • Search for the lowest price from $102

What's the difference between 5-star and 4-star hotels in St. Louis?

Offering a welcoming guest experience and upmarket décor, 4-star hotels are a great option for your St. Louis vacation. These kinds of accommodations generally feature loads of handy amenities that make it easy to unpack and recharge — think complimentary bathrobes, pools and restaurants. Or enjoy even more lavishness at a 5-star hotel designed to spoil you with exclusive perks and amenities. Round-the-clock concierge service, complimentary toiletries and gourmet dining are typically featured at these deluxe properties.

Does St. Louis have any 4-star all-inclusive resorts?

A quick and easy way to search for your dream St. Louis getaway is to click on our "All inclusive" filter tool. You can also find other superb 4-star accommodations such as The Last Hotel and St. Louis Union Station Hotel, Curio Collection by Hilton. Both include outstanding service and a wide range of conveniences for your relaxation and enjoyment.

Are there any 4-star casino hotels in St. Louis?

If you're looking for a stay-and-play getaway, River City Casino & Hotel is a safe bet. Or, you can see where luck takes you at HoteLumiere at the Arch, one more 4-star property in St. Louis sought-after by Expedia guests.

What are the top 4-star apartments in St. Louis?

Book a 4-star apartment in St. Louis and look forward to vacationing in your own private pad. Hickory B - 1 Bedroom Apts is a terrific option and includes amenities like a yard and a deck. Another guest favorite is Steelyard Apartment. An outdoor entertainment area, a barbecue grill and more will make your break here a hassle-free one.

What are the top 4-star hotels in downtown St. Louis?

Book a stay at St. Louis Union Station Hotel, Curio Collection by Hilton and you'll be conveniently placed to explore downtown St. Louis. Situated about 0.2 mi north from the city center, this 4-star hotel also offers premium bedding and pool sun loungers.

Are there any 4-star hotels near Lambert-St. Louis Intl. Airport (STL)?

If you're arriving late or leaving early from St. Louis, it's worth checking out Marriott St. Louis Airport. This 4-star getaway is around 0.5 mi from Lambert-St. Louis Intl. Airport (STL). Another excellent pick is DoubleTree by Hilton St. Louis Airport. It's located approximately 1 mi away.

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