Southeast Missouri, MO
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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
$100 nightly
The price is $113 total per night from Mar 29 to Mar 30
$113 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,007 reviews)
Beds were clean and well made however carpet in room was stained. There was a chicken nugget on the floor in the elevator upon arrival and was still there the next morning. Breakfast was good except for preparer wiping her nose with her plastic serving gloves on. Good coffee and easy check in.
Reviewed on Mar 20, 2026
The Riverview
777 Main St Cape Girardeau MO
$89 nightly
The price is $101 total per night from Mar 23 to Mar 24
$101 total
Mar 23 - Mar 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.4/10 Exceptional! (528 reviews)
Room was nice and roomy. Staff friendly and heat worked well
Reviewed on Mar 16, 2026
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
$94 nightly
The price is $108 total per night from Mar 26 to Mar 27
$108 total
Mar 26 - Mar 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,004 reviews)
Pool not too cold and it was even snowing at one point. Staff was very friendly and helpful. Never had to wait for elevator. Breakfast waffles were excellent. Room was spacious. I’ve stayed in a lot of hotels, and this is one of the best. They get a 100/10 for amenities!
Reviewed on Mar 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
9.8/10 Exceptional! (56 reviews)
Absolutely amazing time as always. Staff is beyond great. Always ready to help and never in the way
Reviewed on Mar 2, 2026
St Francis River: The Blue Yurt and Hot Tub
Fredericktown MO
Stay at this cabin in Fredericktown. Enjoy air conditioning.
8.8/10 Excellent! (20 reviews)
Everything was easy to understand to find the place I wanted. Host is 5 stars
Reviewed on Jan 2, 2026
Johnson's Shut-ins State Park
148 Taum Sauk Trail Middle Brook MO
Stay at this cabin in Middle Brook. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ...
10/10 Exceptional! (1 review)
These newer cabins are clean and have everything you need. Highly recommend!
Reviewed on Nov 5, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Elephant Rocks State Park
5/5(13 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Southeast Missouri State University
4.5/5(77 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Lake Wappapello
4/5(18 reviews)
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Current River State Park
4/5(5 reviews)
Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.
Hawn State Park
5/5(4 reviews)
You can take time to visit Hawn State Park during your travels to Ste Genevieve. Discover the area's coffeehouses or seek out the golf courses.
Big Spring
5/5(2 reviews)
Enjoy an outing to Big Spring during your stay in Van Buren. Wander the forest and riverfront while you're in the area.
Things to do
Night Ghost Tour of Pythian Castle in Springfield Missouri
$20
per adult
100% of travellers recommend
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- Mark Twain National Forest
- Johnson's Shut-ins State Park
- Current River
- Century Casino & Hotel Cape Girardeau
- Elephant Rocks State Park
- Ozark National Scenic Riverways
- Southeast Missouri State University
- Century Casino Caruthersville
- Lake Wappapello
- Current River State Park
- Alley Spring & Mill
- Taum Sauk Mountain State Park
- Echo Bluff State Park
- Hawn State Park
- Rocky Falls
- K Bridge Recreation Area
- Big Spring
- Bonne Terre Mine
- National Shrine of Our Lady of the Miraculous Medal
- Riverfront Park
- Villa Antonio Winery
- Trail of Tears State Park
- Riverfront Bridge Park
- Hunter Valley Winery
- Pickle Springs Natural Area
- St. Francois State Park
- Crown Valley Winery
