Melrose, FL

Travel Guide

A waterfront with Spanish moss-covered trees, a wooden dock, and a distant shoreline.
3 Bedroom House on Private Scenic Lake Mable

3 Bedroom House on Private Scenic Lake Mable

Melrose FL
Stay at this vacation home in Melrose. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lake Geneva and Santa Fe Lake are located ...
9.8/10 Exceptional! (17 reviews)
"Very cozy, peaceful, laid back. It was just what we needed that weekend since we where dropping our son of at UF."

Reviewed on Aug 31, 2026

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3 Bedroom House on Private Scenic Lake Mable
Drury Inn & Suites Gainesville

Drury Inn & Suites Gainesville

3 out of 5
4000 Southwest 40th Blvd Gainesville FL
$105 nightly
The price is $118 total per night from Sep 30 to Oct 1
$118 total
Sep 30 - Oct 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.6/10 Exceptional! (1,613 reviews)
"My family and I have stopped here about five times maybe six within the last two years and we have enjoyed every single day. The staff is always friendly at the rooms are always clean. One thing I love is that they always have coffee available downstairs in the front desk area. We will continue to ..."

Reviewed on Sep 25, 2026

Drury Inn & Suites Gainesville
Sleep Inn & Suites University/Shands

Sleep Inn & Suites University/Shands

2.5 out of 5
4110 SW 40th Boulevard Gainesville FL
$81 nightly
The price is $91 total per night from Oct 18 to Oct 19
$91 total
Oct 18 - Oct 19
Total with taxes and fees
Book a stay at this business-friendly hotel in Gainesville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,300 reviews)
"Clean"

Reviewed on Sep 25, 2026

Sleep Inn & Suites University/Shands
See all 920 properties in Melrose
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
3 Bedroom House on Private Scenic Lake Mable

3 Bedroom House on Private Scenic Lake Mable

Melrose FL
Stay at this vacation home in Melrose. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lake Geneva and Santa Fe Lake are located ...
9.8/10 Exceptional! (17 reviews)
"Very cozy, peaceful, laid back. It was just what we needed that weekend since we where dropping our son of at UF."

Reviewed on Aug 31, 2026

3 Bedroom House on Private Scenic Lake Mable
Lakefront A-Frame · Hot Tub + Fire Pit · Dock · Private Lake

Lakefront A-Frame · Hot Tub + Fire Pit · Dock · Private Lake

Melrose FL
Book a stay at this family-friendly vacation home in Melrose. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lake Geneva and Santa Fe ...
10/10 Exceptional! (3 reviews)
"Beautiful location and property. Host was lovely and attentive. Unique charm.A"

Reviewed on Aug 27, 2026

Lakefront A-Frame · Hot Tub + Fire Pit · Dock · Private Lake
Highland Cow Glamping in a Cozy King Bed Wagon

Highland Cow Glamping in a Cozy King Bed Wagon

Melrose FL
Stay at this cabin in Melrose. Enjoy free WiFi, private pools, and a garden. Popular attractions Lake Blossom Hiking Trailhead and Mike Roess Gold Head Branch ...
Highland Cow Glamping in a Cozy King Bed Wagon
See all properties in Melrose
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Melrose attractions

Single Vision Inc.

See the exotic and native animals who call Single Vision Inc. home during your trip to Melrose. While you're in the area, wander around the parks.
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Frequently asked questions

When is the best time to visit Melrose?
The best time to visit Melrose is from November through March, when the weather is typically cooler and pleasant for exploring. For fewer crowds and better value, the warmer months of June through August are a good option, offering sunny days perfect for outdoor activities.
What cuisines can you find in Melrose?
In Melrose you can find Thai cuisine, with dishes like Pad Thai, Green Curry, and Tom Yum Goong. Travelers can also enjoy Italian favorites such as pasta and pizza, North American comfort food, Mexican dishes like tacos and burritos, and Mediterranean options.
Can I book a refundable hotel in Melrose?
Yes, Expedia offers many flexible booking options, and you can look for refundable hotels in Melrose by entering your dates and using the refundable or fully refundable filter. Always check the hotel's cancellation policy before you book, since terms can vary by hotel, and visit Expedia help center for further details.
Why book a trip to Melrose with Expedia?
Expedia makes it easier to plan your Melrose trip with travel tools, flexible search options, and bookable trip components all in one place. You can organize your plans in one account and use Expedia to help build a trip that fits your budget and travel style. Find out more about how by visiting Expedia's Trip Planner page.
Should I stay in a hotel or vacation rental in Melrose?
The best choice depends on your travel style. Hotels in Melrose can be a good fit for convenience, on-site amenities, and shorter stays, while vacation rentals may offer more space, privacy, and home-style amenities for longer trips, families, or groups. With Expedia, you can compare both options side by side, read traveler reviews, and filter by amenities to find the right fit for your trip.
How can I manage my Melrose trip on Expedia?
Once you've booked your Melrose trip, you can manage it through your Expedia account or the Expedia app. You can view your itinerary, access booking details, make eligible changes, and check for updates in My Trips. The Expedia app can also help you stay organized while you travel.
What if I need help during my Melrose trip?
Expedia offers customer support before, during, and after your Melrose trip. If your plans change or something unexpected happens, you can review your booking in My Trips and use Expedia help center channels for help with eligible changes, cancellations, or travel issues.
How can Expedia help me plan my first trip to Melrose?
If it's your first trip to Melrose, Expedia can help you plan by bringing together stays, flights, activities, traveler reviews, and trip-planning tools in one place. With Expedia's Trip Planner you can compare options, read reviews from other travelers, and build an itinerary that matches your interests and budget.
How can I save on my Melrose hotel booking with Expedia?
Join One Key™ for free to unlock instant discounts with Member Prices on select hotels. You can also earn and use OneKeyCash™* on eligible bookings on Expedia. Booking in advance is usually another great way to save on your Melrose hotel.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.

Cities near Melrose

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