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Find all hotels by Pacifica Hotels in South San Francisco, CA from $138

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Compare rooms and suites by Pacifica Hotels in South San Francisco with rates, reviews, and availability. Most hotels are fully refundable.

"Really loved my 4-day stay! This is a great part of the city, close to shopping and restos, and safe to walk around day and night. The staff were especially warm and wonderful — shout out to Panda and Lourdes!"

$195 total

includes taxes & fees

Jun 16 - Jun 17

"it’s always nice having a suite. We were on the bottom floor and the guests upstairs you could hear every step they made and it was quite loud. I would give your front desk customer service five stars. They deducted $50 from our stay because of the noise. We’ll have to make sure we request the second floor next time. Thank you Julie. "

$220 total

includes taxes & fees

May 27 - May 28

Pacifica Hotels South San Francisco Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Pacifica Hotels hotels in South San Francisco, San Francisco. Known for well-appointed rooms and friendly, personalized service, each of the top Pacifica Hotels South San Francisco hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some South San Francisco Pacifica Hotels locations may even offer extra little benefits and discounts for frequent travelers.