Tuscola Vacation Rentals

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Vacation Rentals in Tuscola

Cozy 1 bedroom RV in tranquil in the Hills of Tuscola with AC relaxing

2.0 star property
Tuscola
8.0 out of 10, Very Good, (3)
"Nice clean comfy rv camper to stay in had it for a week me and another guy working and it was great for what we needed and the owner chad is super friendly and helpful if you have any questions or concerns and don't forget Sam the dog is the best greeter"
United States
Brian B.
$101 nightly
The price is $106
Dec 15 - Dec 16
Total with taxes and fees
Cozy 1 bedroom RV in tranquil in the Hills of Tuscola with AC relaxing

Petite Retreat - Pet Friendly for 1 Pet Only

Abilene
9.8 out of 10, Exceptional, (9)
"Good location and very comfy. "
United States
Wes G.
$98 nightly
The price is $102
Dec 16 - Dec 17
Total with taxes and fees
Petite Retreat - Pet Friendly for 1 Pet Only

Rustic chic guesthouse located right next to HSU & Hendrick Medical Center

Abilene
10.0 out of 10, Exceptional, (65)
"Loved my stay here - adorable, cozy, clean, safe spot! "
United States
Morgan
$198 nightly
The price is $208
Dec 30 - Dec 31
Total with taxes and fees
Rustic chic guesthouse located right next to HSU & Hendrick Medical Center

The Nook - Cozy 1/1 Guesthouse Near ACU

Abilene
9.8 out of 10, Exceptional, (54)
"Comfortable, clean, quiet, thoughtfully accommodated. Will stay here again! "
United States
Shannon K.
$177 nightly
The price is $186
Dec 14 - Dec 15
Total with taxes and fees
The Nook - Cozy 1/1 Guesthouse Near ACU

Tranquill Cabin on Edge of Town (Pet Friendly)

Abilene
10.0 out of 10, Exceptional, (40)
"Loved the house and host!"
United States
Michaela B.
$216 nightly
The price is $227
Dec 9 - Dec 10
Total with taxes and fees
Tranquill Cabin on Edge of Town (Pet Friendly)

Cozy apartment in downtown Abilene, welcome to the back porch!

2.0 star property
Abilene
9.8 out of 10, Exceptional, (7)
" This was a nice little place, I would recommend and I would stay again."
United States
Lorretta
$237 nightly
The price is $250
Dec 10 - Dec 11
Total with taxes and fees
Cozy apartment in downtown Abilene, welcome to the back porch!

Oasis Pool- Schoolie

Abilene
10.0 out of 10, Exceptional, (3)
" Very cool spot!"
United States
Randy L.
$252 nightly
The price is $284
Dec 9 - Dec 10
Total with taxes and fees
Oasis Pool- Schoolie

Eleven South: One - Modern Studio Apartment

Downtown Abilene
10.0 out of 10, Exceptional, (1)
"Space was perfect for traveling alone. Had everything needed. "
United States
Chad S.
$222 nightly
The price is $252
Jan 4 - Jan 5, 2026
Total with taxes and fees
Eleven South: One - Modern Studio Apartment

Mad Men - A Sayles Ranch Home

Abilene
9.4 out of 10, Exceptional, (3)
"We enjoyed our stay. The place was clean and the decor was quirky. It is very close to the Dodge Jones center which made it easy since we were there for a volleyball tournament."
United States
Jodi P.
$304 nightly
The price is $344
Jan 5 - Jan 6, 2026
Total with taxes and fees
Mad Men - A Sayles Ranch Home

NEW! Gorgeous 4BR Dakota Springs Home

Abilene
10.0 out of 10, Exceptional, (2)
"This house was just as described! In a great location, super clean Cute little game room with toys for younger kids. We had a great stay!"
United States
Kelley P.
$384 nightly
The price is $411
Dec 17 - Dec 18
Total with taxes and fees
NEW! Gorgeous 4BR Dakota Springs Home

Iconic West Texas Sunset and Scenic Views

Ovalo
10.0 out of 10, Exceptional, (15)
"A beautiful little hilltop barndominium out in the country with amazing views (especially the sunsets). I will definitely be booking here again for all my future trips to Abilene. "
United States
Seth C.
$366 nightly
The price is $386
Dec 13 - Dec 14
Total with taxes and fees
Iconic West Texas Sunset and Scenic Views

Oma's House on Orange (Pet Friendly)

Abilene
9.6 out of 10, Exceptional, (55)
"It was a great overnight stop for us. Perfect setup with our dog and very comfortable pets!"
United States
Felisa S.
$289 nightly
The price is $305
Dec 9 - Dec 10
Total with taxes and fees
Oma's House on Orange (Pet Friendly)

The Den in the heart of Abilene.

Downtown Abilene
9.0 out of 10, Wonderful, (11)
"Room was very spacious and comfortable had great stay highly recommend"
United States
Earl
$150 nightly
The price is $158
Dec 31 - Jan 1, 2026
Total with taxes and fees
The Den in the heart of Abilene.

The Hayloft - A Sayles Ranch Home

Downtown Abilene
9.2 out of 10, Wonderful, (10)
"We enjoyed the coziness and privacy of this home. Was a great spot for our family to stay on our quick overnight stay in Abilene!Hosts were very prompt and easy to communicate with; would definitely recommended this location to anyone looking for a comfortable, quiet place to stay. "
United States
Austin M.
$271 nightly
The price is $306
Jan 7 - Jan 8, 2026
Total with taxes and fees
The Hayloft - A Sayles Ranch Home

Mulberry Cottage - Downtown; Convention Center

Abilene
10.0 out of 10, Exceptional, (2)
"Thank you! So much for everything you went above and be on. "
United States
Ashley M.
$286 nightly
The price is $323
Jan 7 - Jan 8, 2026
Total with taxes and fees
Mulberry Cottage - Downtown; Convention Center

Three Bedroom, Historic, Charming Spanish Villa in Abilene TX!

Downtown Abilene
10.0 out of 10, Exceptional, (34)
"We absolutely loved this place!! Great location and the house is staged so cozy and beautiful. Our family had a great time thank you!!"
United States
Mandy C.
$378 nightly
The price is $398
Dec 9 - Dec 10
Total with taxes and fees
Three Bedroom, Historic, Charming Spanish Villa in Abilene TX!

Mockingbird Lane – Cozy Rustic Retreat

2.0 star property
Downtown Abilene
$200 nightly
The price is $226
Jan 4 - Jan 5, 2026
Total with taxes and fees
Mockingbird Lane – Cozy Rustic Retreat

Blue Willow Country Cottage!

2.0 star property
Abilene
8.0 out of 10, Very Good, (1)
"I was extremely elated when the owner took matters into her hands after having trouble with my credit card company and VRBO although the complications had absolutely nothing to do with the property or the owner. The property is beautiful well maintained well stocked and so inviting and I am Happy with the owner and the home you might refrain from using Sezzle Afterpay or anything other than your regular cards due to VRBO disclosing card information to management companies only of course, after...
United States
Danielle H.
$330 nightly
The price is $373
Jan 7 - Jan 8, 2026
Total with taxes and fees
Blue Willow Country Cottage!

Raptor Ridge - Your Abilene Adventure Basecamp

2.0 star property
Abilene
$409 nightly
The price is $461
Jan 6 - Jan 7, 2026
Total with taxes and fees
Raptor Ridge - Your Abilene Adventure Basecamp
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Tuscola Hotel Reviews

Find out more about Tuscola

Everything you need to know about Tuscola vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Tuscola vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Tuscola vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Tuscola vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Tuscola. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Tuscola in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $106 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Tuscola rentals

At Expedia, we put the best Tuscola vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Tuscola rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Tuscola vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Tuscola. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Tuscola?

Yes, we offer vacation rentals near top points of interest in Tuscola, or you can choose a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals in Tuscola?

Rustic chic guesthouse located right next to HSU & Hendrick Medical Center: This vacation home rental outside of Tuscola offers a fireplace, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

How many vacation rentals are there in Tuscola?

Choose from 3 Expedia vacation rentals in Tuscola for a memorable vacation.

What’s there to see and do in Tuscola?

Explore the area and family-friendly sights such as Abilene Zoo, or get out into nature at a spot like Kirby Lake. In the larger area, you’ll find Abilene State Park and Mall of Abilene.

What’s a vacation rental in Tuscola like?

Vacation rentals are privately owned properties where you can stay for short or long periods in Tuscola. Vacation rentals offer extras such as kitchens and laundry facilities so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular option for a family getaway.