$205 Cheap Flights from Islip (ISP) to Des Moines (DSM)

View $205 flight on Mon, Apr 27, 2026Opens in a new window

Popular airlines from MacArthur Airport (ISP) to Des Moines International Airport (DSM)

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Cheap Flights from Islip to Des Moines (ISP-DSM)

Prices were available within the past 7 days and start at $205 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

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Frequently asked questions

How much does a flight from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM) cost?
Lock in a cheap one-way flight from $205 or cheap return flight from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM)?
Traveling in is a good way to save, as it's the cheapest month for flights between ISP and DSM. You'll typically find the lowest prices during the off-season.
What is the cheapest airline that flies from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Choose your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest ISP to DSM flight.
How many flights per day from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM)?
Nonstop flights from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM) aren't available daily, so you'll need to take a flight with a layover. Explore your options with our filter tool. Enter your travel details and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from ISP to DSM?
You'll generally find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM)?
To land at Des Moines Intl. Airport (DSM) on schedule, book a flight that leaves from MacArthur Airport (ISP) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM) last-minute?
Booking your plane ticket from ISP to DSM just before your trip is usually more expensive. But if you're flexible with your departure dates and times, you could grab a cheap last-minute fare.
Is it cheaper to book an ISP to DSM flight and hotel package?
Compared with arranging flights and hotels separately, booking an ISP to DSM flight and hotel package with Expedia could result in significant savings. What's more, managing everything in one place will take the stress out of travel planning. Simply pick your flights and choose from our wide range of hotels, then personalize your trip with other add-ons like car rentals and activities.
Can I cancel or change the date of my flight from MacArthur Airport (ISP) to Des Moines Intl. Airport (DSM)?
If you reserved your ISP to DSM flight in the last 24 hours, you may be able to cancel or modify it without any fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
MacArthur
Destination airport
Des Moines Intl.
Distance
1067 mi

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Islip to Des Moines Flights

The cheapest times to fly from Islip to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Islip to Des Moines are during the month of . You can find some of the cheapest flights from Islip to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Islip to Des Moines

Sunday is one of the best days to book for cheap flights from Islip to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Islip to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Islip to Des Moines in 2026. You can also book with separate airlines for your outbound and return journeys, from $205 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Islip to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Islip to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Islip to Des Moines Flights

*Flight schedules are subject to change.

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