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$201 Cheap Flights from Monroe (MLU) to Des Moines (DSM)

View $201 flight on Sat, Sep 12, 2026Opens in a new window

Popular airlines from Monroe, LA (MLU-Monroe Regional) to Des Moines International Airport (DSM)

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Cheap Flights from Monroe to Des Moines (MLU-DSM)

Prices were available within the past 7 days and start at $201 for one-way flights and $388 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Aug 29 - Sun, Aug 30
MLU
Monroe
DSM
Des Moines
$388 Roundtrip, found 19 hours ago
$388
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Aug 29 from Monroe to Des Moines, returning Sun, Aug 30, priced at $388 found 19 hours ago
Delta
Thu, Sep 3 - Tue, Sep 8
MLU
Monroe
DSM
Des Moines
$388 Roundtrip, found 1 day ago
$388
Roundtrip
found 1 day ago
Select Delta flight, departing Thu, Sep 3 from Monroe to Des Moines, returning Tue, Sep 8, priced at $388 found 1 day ago
American Airlines
Mon, Aug 10 - Mon, Aug 17
MLU
Monroe
DSM
Des Moines
$403 Roundtrip, found 1 day ago
$403
Roundtrip
found 1 day ago
Select American Airlines flight, departing Mon, Aug 10 from Monroe to Des Moines, returning Mon, Aug 17, priced at $403 found 1 day ago
American Airlines
Fri, Oct 9 - Sat, Oct 10
MLU
Monroe
DSM
Des Moines
$407 Roundtrip, found 1 day ago
$407
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 9 from Monroe to Des Moines, returning Sat, Oct 10, priced at $407 found 1 day ago
Delta
Sat, Aug 29 - Sun, Aug 30
MLU
Monroe
DSM
Des Moines
$408 Roundtrip, found 19 hours ago
$408
Roundtrip
found 19 hours ago
Select Delta flight, departing Sat, Aug 29 from Monroe to Des Moines, returning Sun, Aug 30, priced at $408 found 19 hours ago
American Airlines
Sat, Aug 8 - Fri, Aug 14
MLU
Monroe
DSM
Des Moines
$418 Roundtrip, found 4 days ago
$418
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Aug 8 from Monroe to Des Moines, returning Fri, Aug 14, priced at $418 found 4 days ago
Delta
Sat, Oct 10 - Sun, Oct 11
MLU
Monroe
DSM
Des Moines
$427 Roundtrip, found 14 hours ago
$427
Roundtrip
found 14 hours ago
Select Delta flight, departing Sat, Oct 10 from Monroe to Des Moines, returning Sun, Oct 11, priced at $427 found 14 hours ago
American Airlines
Sat, Aug 29 - Sun, Aug 30
MLU
Monroe
DSM
Des Moines
$437 Roundtrip, found 19 hours ago
$437
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Aug 29 from Monroe to Des Moines, returning Sun, Aug 30, priced at $437 found 19 hours ago
American Airlines
Sat, Aug 8 - Fri, Aug 14
MLU
Monroe
DSM
Des Moines
$452 Roundtrip, found 4 days ago
$452
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sat, Aug 8 from Monroe to Des Moines, returning Fri, Aug 14, priced at $452 found 4 days ago
American Airlines
Sat, Aug 29 - Sun, Aug 30
MLU
Monroe
DSM
Des Moines
$468 Roundtrip, found 19 hours ago
$468
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Aug 29 from Monroe to Des Moines, returning Sun, Aug 30, priced at $468 found 19 hours ago

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 10 minutes. Flights from $649
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center10 min
Flights from $649

Frequently asked questions

How much does a flight from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) cost?
You can find cheap one-way flights from $201 and cheap return flights from $388 Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) with Expedia. One-way flights typically cost between $323 and $948, and return flights often range between $466 and $1617. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
The cheapest month to fly from MLU to DSM is August when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
Enter MLU to DSM and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
To find a cheap flight from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
Sort flights by "Departure (earliest)" on Expedia to find the earliest flight from MLU to DSM. To compare more early flights, use the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
For flights from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.), the most popular departure times are in the early morning, from 6am to 9am. This time window accounts for about 31% of total traffic, indicating a preference for morning travel. Major carriers like Delta Air Lines and United Airlines operate flights during this period, making it convenient for you to start your day with an early flight.
How long does it take to fly from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
Flying from MLU to DSM with a connection usually takes about 4 hours 50 minutes, traveling roughly 630 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
Select the "Business class" and "First class" filters when looking for MLU to DSM flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) flight with Expedia?
It's easy to earn miles on a Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Des Moines from Monroe Regional (MLU)?
If you're planning to travel to Des Moines from Monroe Regional (MLU), you can fly into Des Moines Intl. (DSM) Some flights may connect through major hubs like Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Des Moines. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) at the last minute?
Typically, booking a last minute flight from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package?
Securing a Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) Des Moines Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.)?
If you booked your Monroe, LA (MLU-Monroe Regional) to Des Moines, IA (DSM-Des Moines Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Monroe Regional
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta
Roundtrip price
$388
Distance
629 mi

Book with confidence

Monroe to Des Moines Flights

The cheapest times to fly from Monroe to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Monroe to Des Moines are during the month of August. You can find some of the cheapest flights from Monroe to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Monroe to Des Moines

Sunday is one of the best days to book for cheap flights from Monroe to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Monroe to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Monroe to Des Moines in 2026. You can also book with separate airlines for your outbound and return journeys, from $201 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Monroe to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Monroe to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Monroe to Des Moines Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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