$440 Cheap Flights from Milan (MXP) to Des Moines (DSM)

View $440 flight on Sat, Mar 7, 2026Opens in a new window

Popular airlines from Milan Malpensa Airport (MXP) to Des Moines International Airport (DSM)

Cheap Flights from Milan to Des Moines (MXP-DSM)

Prices were available within the past 7 days and start at $440 for one-way flights and $720 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Mon, Dec 1 - Fri, Apr 24
MXP
Milan
DSM
Des Moines
$720 Roundtrip, found 18 hours ago
$720
Roundtrip
found 18 hours ago
Select British Airways flight, departing Mon, Dec 1 from Milan to Des Moines, returning Fri, Apr 24, priced at $720 found 18 hours ago
British Airways
Sat, Nov 15 - Wed, Nov 19
MXP
Milan
DSM
Des Moines
$727 Roundtrip, found 3 days ago
$727
Roundtrip
found 3 days ago
Select British Airways flight, departing Sat, Nov 15 from Milan to Des Moines, returning Wed, Nov 19, priced at $727 found 3 days ago
British Airways
Mon, Dec 1 - Fri, Apr 24
MXP
Milan
DSM
Des Moines
$732 Roundtrip, found 18 hours ago
$732
Roundtrip
found 18 hours ago
Select British Airways flight, departing Mon, Dec 1 from Milan to Des Moines, returning Fri, Apr 24, priced at $732 found 18 hours ago
American Airlines
Fri, Dec 12 - Tue, Dec 16
MXP
Milan
DSM
Des Moines
$755 Roundtrip, found 3 days ago
$755
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Dec 12 from Milan to Des Moines, returning Tue, Dec 16, priced at $755 found 3 days ago
British Airways
Mon, Dec 1 - Fri, Apr 24
MXP
Milan
DSM
Des Moines
$760 Roundtrip, found 18 hours ago
$760
Roundtrip
found 18 hours ago
Select British Airways flight, departing Mon, Dec 1 from Milan to Des Moines, returning Fri, Apr 24, priced at $760 found 18 hours ago
British Airways
Mon, Dec 1 - Fri, Apr 24
MXP
Milan
DSM
Des Moines
$773 Roundtrip, found 18 hours ago
$773
Roundtrip
found 18 hours ago
Select British Airways flight, departing Mon, Dec 1 from Milan to Des Moines, returning Fri, Apr 24, priced at $773 found 18 hours ago
British Airways
Mon, Dec 1 - Fri, Apr 24
MXP
Milan
DSM
Des Moines
$780 Roundtrip, found 18 hours ago
$780
Roundtrip
found 18 hours ago
Select British Airways flight, departing Mon, Dec 1 from Milan to Des Moines, returning Fri, Apr 24, priced at $780 found 18 hours ago
Delta
Fri, Dec 12 - Mon, Dec 15
MXP
Milan
DSM
Des Moines
$796 Roundtrip, found 3 days ago
$796
Roundtrip
found 3 days ago
Select Delta flight, departing Fri, Dec 12 from Milan to Des Moines, returning Mon, Dec 15, priced at $796 found 3 days ago
Iberia
Tue, Aug 18 - Fri, Aug 28
MXP
Milan
DSM
Des Moines
$818 Roundtrip, found 2 days ago
$818
Roundtrip
found 2 days ago
Select Iberia flight, departing Tue, Aug 18 from Milan to Des Moines, returning Fri, Aug 28, priced at $818 found 2 days ago
Air Canada
Sun, Nov 30 - Fri, Apr 24
MXP
Milan
DSM
Des Moines
$862 Roundtrip, found 10 hours ago
$862
Roundtrip
found 10 hours ago
Select Air Canada flight, departing Sun, Nov 30 from Milan to Des Moines, returning Fri, Apr 24, priced at $862 found 10 hours ago

Frequently asked questions

How much does a flight from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM) cost?
Secure a cheap one-way flight from $440 or cheap return flight from $720 from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM)?
The cheapest month to fly from MXP to DSM is December, when demand is low. Off-peak season is generally when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM)?
Expedia's filter tool lets you easily compare different airlines, flight durations and fares all in one place. Select your preferences, then sort by "Price (lowest to highest)" to find out which carrier offers the cheapest MXP to DSM flight.
How many flights per day from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM)?
You'll have to hop on a flight with a layover if you're traveling from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM). There are no daily direct flights on this route. However, just filter your search to include one or more stops to find an option that works for you.
What day of the week has the most flights from MXP to DSM?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary depending on a number of factors, including the time of year and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM)?
To avoid potential delays on the Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM) route, fly before 3 PM. Later departures have a 22% higher chance of being canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM) last-minute?
Waiting until just before your departure to book a flight from MXP to DSM often results in higher prices. Although you may find some last-minute discounts, there's no guarantee. Keep your travel plans flexible to boost your chances of getting a bargain.
Is it cheaper to book a MXP to DSM flight and hotel package?
You'll generally save money by booking a MXP to DSM flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've chosen your preferred accommodations and flights, you can add extras such as car rentals, tours and activities.
Can I cancel or change the date of my flight from Malpensa Intl. Airport (MXP) to Des Moines Intl. Airport (DSM)?
If you booked your MXP to DSM flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of fare you have, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, visit our Customer Service portal if you'd like more information.

Travel information

Origin airport
Malpensa Intl.
Destination airport
Des Moines Intl.
Airlines serving
Air Canada, British Airways, Finnair, Iberia, Lufthansa
Roundtrip price
$719
Distance
4752 mi

Book with confidence

Milan to Des Moines Flights

The cheapest times to fly from Milan to Des Moines

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Milan to Des Moines are during the month of December. You can find some of the cheapest flights from Milan to Des Moines with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Milan to Des Moines

Sunday is one of the best days to book for cheap flights from Milan to Des Moines: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Milan to Des Moines

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Milan to Des Moines in 2025. You can also book with separate airlines for your outbound and return journeys, from $440 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Milan to Des Moines flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Milan to Des Moines airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Milan to Des Moines Flights

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*Available to One Key members.