Title: Florida Keys Spa Vacations 2026 | Expedia.com ![](https://images.trvl-media.com/place/6246822/f00ad239-b8ad-4f0c-b162-acc6426db1e2.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Florida Keys Spa Vacations ## Book a Spa Hotel + Flight or Car together to unlock savings ## Top Spa vacation packages in Florida Keys Price found within the past 48 hours. Click for updated prices. ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/8671ba74_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hawks Cay Resort Save 100% on your flight $551 per person May 25 - May 28 found 16 hours ago Roundtrip flight included New York (NYC) to Miami (MIA) 8/10 Very Good! (1,015 reviews) Very nice property. Very clean great view. Pools were awesome! The only complaint is they do not have prices on anything in their food market/cafe. Reviewed on Mar 23, 2026 ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4608d7e2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Cheeca Lodge & Spa Matecumbe $1,225 per person Apr 26 - Apr 30 found 1 day ago Roundtrip flight included Boston (BOS) to Miami (MIA) 9.2/10 Wonderful! (1,308 reviews) They should have had a newsletter with activities. Reviewed on Mar 23, 2026 ![Islander Resort](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/f8d2863e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Islander Resort Matecumbe $1,190 per person Apr 24 - Apr 27 found 1 day ago Roundtrip flight included Boston (BOS) to Miami (MIA) 9.2/10 Wonderful! (1,014 reviews) Room was awesome, resort was beautiful, loved the patio outside of our room, and enjoyed free popsicles by the pool. The only thing that left something to be desired was the gym it was good, but not great. Reviewed on Mar 23, 2026 ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/7c755dc1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton Save 100% on your flight $1,685 per person Apr 24 - Apr 30 found 10 hours ago Roundtrip non-stop flight included Wichita (ICT) to Miami (MIA) 8.6/10 Excellent! (1,012 reviews) 100% the best resort at Key Largo. Definitely reccomend Hammock beach side of resort. Beach was beautiful, adult pool amazing! They have top of the line amenities. Hoping to be back soon! Reviewed on Mar 24, 2026 Don't see what you're looking for? See all available trips from Columbus to Florida Keys [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-25/2026-05-02/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Spa vacations in Florida Keys Price found within the past 48 hours. Click for updated prices. ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4608d7e2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Cheeca Lodge & Spa Matecumbe $1,225 per person Apr 26 - Apr 30 found 1 day ago Roundtrip flight included Boston (BOS) to Miami (MIA) 9.2/10 Wonderful! (1,308 reviews) They should have had a newsletter with activities. Reviewed on Mar 23, 2026 Don't see what you're looking for? See all available trips from Columbus to Florida Keys [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-25/2026-05-02/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Spa vacations in Florida Keys Price found within the past 48 hours. Click for updated prices. ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/8671ba74_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hawks Cay Resort Save 100% on your flight $551 per person May 25 - May 28 found 16 hours ago Roundtrip flight included New York (NYC) to Miami (MIA) 8/10 Very Good! (1,015 reviews) Very nice property. Very clean great view. Pools were awesome! The only complaint is they do not have prices on anything in their food market/cafe. Reviewed on Mar 23, 2026 ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4608d7e2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Cheeca Lodge & Spa Matecumbe $863 per person Apr 27 - Apr 30 found 11 hours ago Roundtrip flight included Boston (BOS) to Miami (MIA) 9.2/10 Wonderful! (1,308 reviews) They should have had a newsletter with activities. Reviewed on Mar 23, 2026 Don't see what you're looking for? See all available trips from Columbus to Florida Keys [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-25/2026-05-02/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Spa vacations in Florida Keys Price found within the past 48 hours. Click for updated prices. ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/8671ba74_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hawks Cay Resort Save 100% on your flight $848 per person May 26 - May 30 found 7 hours ago Roundtrip flight included Indianapolis (IND) to Miami (MIA) 8/10 Very Good! (1,015 reviews) Very nice property. Very clean great view. Pools were awesome! The only complaint is they do not have prices on anything in their food market/cafe. Reviewed on Mar 23, 2026 ![The Hammocks at Marathon](https://images.trvl-media.com/lodging/1000000/450000/448300/448273/374bb67d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Hammocks at Marathon Save 100% on your flight $881 per person May 28 - Jun 1 found 12 hours ago Roundtrip flight included Newark Liberty Intl. Airport (EWR) to Miami (MIA) 9/10 Wonderful! (130 reviews) The suite / 2 bedroom was nice and clean. The grounds well kept. Everyone was friendly until they wanted us to change rooms. They checked us in and after a little while, long enough for us to settle, start showers and phone calls home, they insisted we move. Said we were in the wrong room. I checked the room number written on the key envelope of the key that was given to me (it was the room we were in) gave me directions; we unpacked, settled, and then started insisting we pack up and move. We declined as we had indeed booked a 2 bedroom suite, which is what we were in. We were confused. Then we were told the other guest would be there longer than we would and needed the room. ??? Such a stressful checkin. Along with this, Expedia did not disclose there would be resort fees $28 per day. So they charged me in addition to what I had prepaid through Expedia. Reviewed on Mar 11, 2026 ![Hyatt Vacation Club at Windward Pointe, Key West](https://images.trvl-media.com/lodging/1000000/870000/868700/868697/af5a58cd_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Vacation Club at Windward Pointe, Key West $1,347 per person May 25 - May 29 found 1 day ago Roundtrip non-stop flight included Albany (ALB) to Key West (EYW) 9.4/10 Exceptional! (1,020 reviews) Everything was clean in the room just a bit outdated, the rooms probably could use some updating. However, the pool area and grounds were absolutely beautiful. I would stay again just for the grounds and pool. It is next to the airport so during the day there are a lot of planes going out with some flight noise. Reviewed on Mar 24, 2026 Don't see what you're looking for? See all available trips from Columbus to Florida Keys [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-25/2026-05-02/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=MIA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Top Spa Florida Keys Hotels ![Margaritaville Beach House Key West](https://images.trvl-media.com/lodging/49000000/48720000/48713900/48713884/5fd7b8bf_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Margaritaville Beach House Key West 2001 South Roosevelt Boulevard Key West FL - 4 min drive from Duval Street Book a stay at this beach hotel in Key West. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the pool and the restaurant ... 8.8/10 Excellent! (1,800 reviews) This Margaritaville has different amenities than others, so our expectations might have been high. We were bummed to learn they do not have pool side or beach service. The pool was small, but they do have a small hot tub, however, it is older and not the best. The room we stayed in was a 2 bedroom ... Reviewed on Mar 25, 2026 [](https://expedia.com/Key-West-Hotels-Margaritaville-Beach-House-Key-West.h48713884.Hotel-Information) ![Havana Cabana at Key West ](https://images.trvl-media.com/lodging/22000000/21250000/21241100/21241090/62539afb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Havana Cabana at Key West 3420 N. Roosevelt Blvd Key West FL - 6 min drive from Duval Street Book a stay at this business-friendly hotel in Key West. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the pool and the helpful ... 9/10 Wonderful! (1,712 reviews) Poolside is great! Staff is kind and friendly. Outdoor pool well taken care of. Great food, fun bar. Dogs welcome. So much fun! Reviewed on Mar 24, 2026 [](https://expedia.com/Key-West-Hotels-Havana-Cabana-At-Key-West.h21241090.Hotel-Information) ![Blue Flamingo Resort Key West](https://images.trvl-media.com/lodging/13000000/12600000/12599300/12599231/c4b850d1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Blue Flamingo Resort Key West 3820 North Roosevelt Boulevard Key West FL - 7 min drive from Duval Street Book a stay at this family-friendly hotel in Key West. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the helpful staff ... 8.2/10 Very Good! (1,996 reviews) Check in staff was great! Reviewed on Mar 25, 2026 [](https://expedia.com/Key-West-Hotels-24-North-Hotel-Key-West-Newly-Renovated.h12599231.Hotel-Information) [See all 8,317 properties in Florida Keys](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6023765) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. 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Savings not available on all packages.