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Our top choices for Panhandle Key hotels

A beach with palm trees and lounge chairs.
A swimming pool with clear blue water, surrounded by a white deck and a black metal fence.
A balcony with two blue lounge chairs, a wooden ceiling, and a view of the ocean and palm trees.
A waterfront hotel with multiple floors, palm trees, and a calm reflective pool.

1. Chesapeake Beach Resort

Chesapeake Beach Resort
8.3 mi from Panhandle Key
United States
Dianne
$197 nightly
$221 total
Oct 20 - Oct 21
Total with taxes and fees
Chesapeake Beach Resort
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.

2. Cheeca Lodge & Spa

Cheeca Lodge & Spa
8 mi from Panhandle Key
United States
James
$244 nightly
$274 total
Oct 20 - Oct 21
Total with taxes and fees
Cheeca Lodge & Spa
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A paved pathway leading to a beach with palm trees and a view of the ocean.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.

3. Islander Resort

Islander Resort
8.1 mi from Panhandle Key
United States
Bryan
$280 nightly
$315 total
Nov 15 - Nov 16
Total with taxes and fees
Islander Resort
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a view of the ocean in the background.
A beachside resort with thatched-roof huts, palm trees, and a sandy area with rocks and wooden chairs.
A resort with thatched-roof structures, palm trees, and a sandy beach area.
A wooden deck with a thatched roof structure, wooden chairs, and a table, overlooking a tropical landscape with palm trees and a clear sky.

4. Coconut Cove Resort and Marina

Coconut Cove Resort and Marina
8.7 mi from Panhandle Key
United States
Hailey Ritch and Patrick
$149 nightly
$168 total
Oct 26 - Oct 27
Total with taxes and fees
Coconut Cove Resort and Marina
A beach with rows of sun loungers and palm trees.
Three Adirondack chairs facing a sunset over a body of water.
A marina with a boat docked at a wooden pier, surrounded by palm trees and buildings.
A spacious room with a high ceiling, a ceiling fan, a dining table with chairs, a sofa, and a television mounted on the wall.

5. Ragged Edge Resort & Marina

Ragged Edge Resort & Marina
10.2 mi from Panhandle Key
United States
Nathalie
$172 nightly
$194 total
Oct 29 - Oct 30
Total with taxes and fees
Ragged Edge Resort & Marina
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A beachside patio with a thatched roof, two lounge chairs, and a view of the ocean.

6. The Islands of Islamorada

The Islands of Islamorada
8.2 mi from Panhandle Key
United States
Christian
$534 nightly
$600 total
Oct 21 - Oct 22
Total with taxes and fees
The Islands of Islamorada
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A beach with palm trees, a dock, and lounge chairs.
An aerial view of a resort with a swimming pool, palm trees, and a dock.
A resort pool with palm trees, beach chairs, and umbrellas.

7. Amara Cay Resort

Amara Cay Resort
8.1 mi from Panhandle Key
United States
Ronald
$208 nightly
$234 total
Oct 21 - Oct 22
Total with taxes and fees
Amara Cay Resort
A beach with a thatched umbrella, lounge chairs, and a clear view of the ocean.
A compact kitchen with modern appliances, a dining area with a sofa, and a large window providing natural light.
A beach view with palm trees and a thatched-roof structure.
A sign for Matecumbe Resort with a full kitchen and heated pool.

8. Matecumbe Resort

Matecumbe Resort
8.9 mi from Panhandle Key
United States
angel
$158 nightly
$177 total
Nov 18 - Nov 19
Total with taxes and fees
Matecumbe Resort
A balcony with wicker chairs, a small table with drinks, and a view of the beach and ocean.
A coastal resort with a beach, a swimming pool, and multiple buildings.
An outdoor dining area with round tables and chairs, a thatched roof, and a view of the sea.
A beach with palm trees, a clear blue sky, and a calm sea.

9. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
8.5 mi from Panhandle Key
United States
Liosbel
$304 nightly
$342 total
Nov 2 - Nov 3
Total with taxes and fees
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Exterior
A view from a window overlooking a beach with palm trees and a wooden pier.
An indoor wooden structure with a thatched roof, multiple hanging spherical lights, and a central seating area.
An aerial view of a resort with a swimming pool, lounge chairs, and palm trees.

10. Casa Morada

Casa Morada
7.9 mi from Panhandle Key
United States
David
$167 nightly
$187 total
Oct 28 - Oct 29
Total with taxes and fees
Casa Morada
A beach with palm trees, thatched-roof huts, and lounge chairs.
A building facade with the text "Buzzy Plims" and a website address. There are two potted plants and a staircase leading up to the entrance.
A modern kitchen with a microwave, stove, and refrigerator. There is a dining area with a table and chairs.
A living room with a sofa, armchair, coffee table, and lamp. There is a dining area with a table and chairs. The room has a kitchen area with a stove and cabinets.

11. Breezy Palms Resort

Breezy Palms Resort
8.1 mi from Panhandle Key
United States
Gavin
$123 nightly
$139 total
Oct 21 - Oct 22
Total with taxes and fees
Breezy Palms Resort
A bedroom with a large bed, a sliding glass door to a balcony, a wooden cabinet, and a kitchen area with a microwave.
A swimming pool with a 5 ft depth marker, surrounded by palm trees and a white picket fence.
A hotel room with two beds, each with a different patterned bedspread, a nightstand with a lamp, framed artwork on the wall, and an air conditioning unit.
A bedroom with a bed, a nightstand, a chair, and a door.

12. The Ocean View Inn & Pub

The Ocean View Inn & Pub
8.6 mi from Panhandle Key
United States
Maria
$186 nightly
$210 total
Oct 28 - Oct 29
Total with taxes and fees
The Ocean View Inn & Pub
A wooden deck with rustic furniture, a grill, and a view of the beach and palm trees.
A beachfront property with a staircase leading to a light blue building, palm trees, and a clear view of the ocean.
A beachfront property with a white building, a balcony with a white railing, and palm trees.
A beach with wooden lounge chairs, palm trees, and a clear view of the ocean.

13. La Jolla Resort

La Jolla Resort
7.9 mi from Panhandle Key
United States
Brett
$168 nightly
$189 total
Oct 22 - Oct 23
Total with taxes and fees
La Jolla Resort
A modern kitchen with white cabinets, a microwave, and a dining area with a table and chairs.
A row of floating cottages with balconies and outdoor seating, docked along a waterway.
A pool area with a white fence, a lifebuoy, and palm trees in the background.
A boat with a covered deck, metal railings, and a table with chairs.

14. Treasure Harbor

Treasure Harbor
10.1 mi from Panhandle Key
United States
Laura
$244 nightly
$275 total
Oct 20 - Oct 21
Total with taxes and fees
Treasure Harbor
A beachside lounge with a wooden deck, thatched roof, and tropical plants.
A waterfront property with a paved walkway, palm trees, and a white building with a dock.
Exterior
A resort with a central swimming pool surrounded by palm trees and a view of the ocean.

15. Bayside Villas by Islander Resort

Bayside Villas by Islander Resort
7.9 mi from Panhandle Key
United States
Brian
$298 nightly
$336 total
Oct 27 - Oct 28
Total with taxes and fees
Bayside Villas by Islander Resort
A row of beachside cottages with colorful exteriors, each with a beach chair and umbrella.
A beach with colorful buildings, kayaks, and lounge chairs.
A row of colorful beach huts with palm trees in the background.
A resort with a pool surrounded by palm trees and a view of the ocean.

16. La Siesta Resort & Villas

La Siesta Resort & Villas
8 mi from Panhandle Key
United States
Brianne
$231 nightly
$260 total
Nov 18 - Nov 19
Total with taxes and fees
La Siesta Resort & Villas
A modern kitchen with a central island, a dining area with a view, and a living space with a balcony overlooking the ocean.
A modern two-story beachfront property with balconies, a pool, and a sandy beach area.
A coastal resort with a marina, clear blue water, and lush greenery.
A beachside resort with a pool area, lounge chairs, and palm trees.

17. Pines & Palms Resort

Pines & Palms Resort
8 mi from Panhandle Key
United States
Michael
$248 nightly
$279 total
Oct 20 - Oct 21
Total with taxes and fees
Pines & Palms Resort
A beachside patio with white furniture, palm trees, and a thatched umbrella.
A beach with palm trees, a thatched umbrella, and lounge chairs.
A pool area with lounge chairs and a sign indicating a drop-off zone.
A deck with white lounge chairs and a bench, overlooking a beach with palm trees and a thatched roof structure.

18. Drop Anchor

Drop Anchor
8.9 mi from Panhandle Key
United States
Payman
$173 nightly
$190 total
Oct 20 - Oct 21
Total with taxes and fees
Drop Anchor
A wooden dock extending over calm turquoise water, lined with white railings and palm trees.
A swimming pool with a rock waterfall feature and a 3 ft depth marker.
A waterfront patio with outdoor seating, a yellow umbrella, and a view of the water.
A wooden sign with the name 'Creekside' above a white pergola entrance.

19. Creekside Inn

Creekside Inn
12.1 mi from Panhandle Key
United States
Terry
$129 nightly
$145 total
Nov 18 - Nov 19
Total with taxes and fees
Creekside Inn
A beachside lounge area with sun loungers, a thatched structure, and a view of the ocean.
A spacious living area with a round dining table, a sofa, and a TV mounted on the wall.
A two-story building with a balcony, surrounded by palm trees and a sandy ground.
A compact, well-lit room with a bed, bedside table, and a small seating area.

20. Sands of Islamorada

Sands of Islamorada
8.1 mi from Panhandle Key
United States
Nicolas
$203 nightly
$228 total
Oct 22 - Oct 23
Total with taxes and fees
Sands of Islamorada
View all properties

Compare popular hotels close to Panhandle Key

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A beach with palm trees and lounge chairs.
Chesapeake Beach Resort
9.4
Exceptional
1,799 reviews
View
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
Cheeca Lodge & Spa
9.2
Wonderful
1,485 reviews
View
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
Islander Resort
9.4
Exceptional
1,146 reviews
View
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a view of the ocean in the background.
Coconut Cove Resort and Marina
9.0
Wonderful
300 reviews
View
A beach with rows of sun loungers and palm trees.
Ragged Edge Resort & Marina
9.6
Exceptional
275 reviews
View

Hotels recommended for families near Panhandle Key

A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.

Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
$244 nightly
$274 total
Oct 20 - Oct 21
Total with taxes and fees
Cheeca Lodge & Spa
A wooden deck with two lounge chairs, a table with two glasses of champagne and red roses, and a view of the beach and ocean.
A beach with palm trees, a dock, and lounge chairs.
An aerial view of a resort with a swimming pool, palm trees, and a dock.
A resort pool with palm trees, beach chairs, and umbrellas.

Amara Cay Resort

Amara Cay Resort
Matecumbe
$208 nightly
$234 total
Oct 21 - Oct 22
Total with taxes and fees
Amara Cay Resort
A wooden deck with rustic furniture, a grill, and a view of the beach and palm trees.
A beachfront property with a staircase leading to a light blue building, palm trees, and a clear view of the ocean.
A beachfront property with a white building, a balcony with a white railing, and palm trees.
A beach with wooden lounge chairs, palm trees, and a clear view of the ocean.

La Jolla Resort

La Jolla Resort
Matecumbe
$168 nightly
$189 total
Oct 22 - Oct 23
Total with taxes and fees
La Jolla Resort
A beach with palm trees, thatched-roof huts, and lounge chairs.
A building facade with the text "Buzzy Plims" and a website address. There are two potted plants and a staircase leading up to the entrance.
A modern kitchen with a microwave, stove, and refrigerator. There is a dining area with a table and chairs.
A living room with a sofa, armchair, coffee table, and lamp. There is a dining area with a table and chairs. The room has a kitchen area with a stove and cabinets.

Breezy Palms Resort

Breezy Palms Resort
Matecumbe
$123 nightly
$139 total
Oct 21 - Oct 22
Total with taxes and fees
Breezy Palms Resort
An aerial view of a resort with two swimming pools surrounded by palm trees and sun loungers.
A paved pathway leading to a beach with palm trees and a view of the ocean.
A wooden pier leading to a beach with palm trees and a row of beach huts.
A beachside patio with wooden furniture, a thatched roof, and a view of the ocean.

Islander Resort

Islander Resort
Matecumbe
$280 nightly
$315 total
Nov 15 - Nov 16
Total with taxes and fees
Islander Resort
A beachside lounge with a wooden deck, thatched roof, and tropical plants.
A waterfront property with a paved walkway, palm trees, and a white building with a dock.
Exterior
A resort with a central swimming pool surrounded by palm trees and a view of the ocean.

Bayside Villas by Islander Resort

Bayside Villas by Islander Resort
Matecumbe
$298 nightly
$336 total
Oct 27 - Oct 28
Total with taxes and fees
Bayside Villas by Islander Resort
A balcony with a view of a beach, a pool, and a thatched-roof structure.
An aerial view of a marina with docked boats, a building with balconies, and a beach area.
A pool area with lounge chairs and umbrellas, surrounded by palm trees and buildings.
A beach scene with two yellow beach chairs and a person lying on one.

Hadley Resort and Marina

Hadley Resort and Marina
Matecumbe
$181 nightly
$204 total
Oct 28 - Oct 29
Total with taxes and fees
Hadley Resort and Marina
A modern kitchen with a central island, a dining area with a view, and a living space with a balcony overlooking the ocean.
A modern two-story beachfront property with balconies, a pool, and a sandy beach area.
A coastal resort with a marina, clear blue water, and lush greenery.
A beachside resort with a pool area, lounge chairs, and palm trees.

Pines & Palms Resort

Pines & Palms Resort
Matecumbe
$248 nightly
$279 total
Oct 20 - Oct 21
Total with taxes and fees
Pines & Palms Resort

Top Panhandle Key Hotel Reviews

La Jolla Resort

La Jolla Resort

10/10 Excellent
"It looks a little rough when you drive in but wow - once you are at the resort it is homey and clean and nice. The staff is super helpful. The office has cold drinks, ice, snacks, beach towels, snorkel gear, life vests, fishing gear (and bait), paddles, and other things to make the stay enjoyable. Off the back there is swim access, lounge chairs, hammocks, bocce ball. I’m probably forgetting other things. The rooms are spacious and well equipped for a short or longer term stay. Highly recommend."
Olga 2-night trip
Posted 1 hour ago
La Jolla Resort
Amara Cay Resort

Amara Cay Resort

8/10 Good
"Clean room and nice amenities. Parking was good. Common areas very well designed."
Alfonso 1-night trip
Posted 2 hours ago
Amara Cay Resort
Chesapeake Beach Resort

Chesapeake Beach Resort

10/10 Excellent
"Very professional reception, room clean staff very polite"
Rene 1-night trip
Posted 7 hours ago
Chesapeake Beach Resort
Islander Resort

Islander Resort

10/10 Excellent
"We had an incredible stay here. Great views, delicious food, and the staff went above and beyond to make our stay exceptional. We already can’t wait to come back!"
Michaela 1-night trip
Posted 9 hours ago
Islander Resort
Casa Morada

Casa Morada

10/10 Excellent
"."
angela 3-night trip
Posted 1 day ago
Casa Morada
Charming house boat with 2 bedrooms and WiFi, AC in wonderful Islamorada

Charming house boat with 2 bedrooms and WiFi, AC in wonderful Islamorada

10/10 Excellent
"100% will go again!!! The houseboat was even more than expected!! Perfect location, beautiful inside and out and the most beautiful and perfect sunrise and sunset you could imagine!! Everything was amazing but the hosts, Manuel and Daniel, MADE OUR TRIP!!! They helped us unload our car and put everything on/off the transportation boat and the explaining of the boat was top notch!! We had talked about how we wanted to go to Alligator Reef and the Sandbar one day but didn't want a boat with alot of people on it. They offered to to take us and we freaking loved it!!! They both brought thier girlfriends, cooked some lobster for us and we even got to pet nurse sharks after snorkeling!!! The "fee" for them taking us was nothing compared to the memories just from that day!!! We had a great time with some awsome people in some of the most beautiful water we have ever seen!!! Best VRBO host we have ever had and we will definitely be back!!!"
Natalie H. 3-night trip
Posted 1 month ago
Charming house boat with 2 bedrooms and WiFi, AC in wonderful Islamorada
Sleeps 8 | Sunset + Boat Basin | Islamorada

Sleeps 8 | Sunset + Boat Basin | Islamorada

10/10 Excellent
"This is a clean, nice property in the Florida Keys. The host was excellent and easy to work with. It's a great location that we have stayed in before and will be back again soon."
Paige C. 7-night trip
Posted 2 months ago
Sleeps 8 | Sunset + Boat Basin | Islamorada
5 bedroom - Deep Dockage & Heated Pool in Islamorada.

5 bedroom - Deep Dockage & Heated Pool in Islamorada.

10/10 Excellent
"I was selfishly going to give it one star across the board. Why? Because if I give the well deserved 5 stars, then the property will become more popular and less available for ME in the future. But seriously ... I cannot recommend the property and the hosts enough. It's all we expected and more. Don't book this unless you are ready to have a perfectly relaxing experience with no drama."
Michel V. 8-night trip
Posted 2 months ago
5 bedroom - Deep Dockage & Heated Pool in Islamorada.
Isla Key Lime: Boutique Resort, FREE Boat Dockage Sept-Oct Only!

Isla Key Lime: Boutique Resort, FREE Boat Dockage Sept-Oct Only!

10/10 Excellent
"Beautiful unit. Parking was a bit tight at times, but otherwise, a perfect location. Close to everything and great amenities."
Carrie M. 7-night trip
Posted 3 months ago
Isla Key Lime: Boutique Resort, FREE Boat Dockage Sept-Oct Only!

Other attractions near Panhandle Key

A stone monument with a relief sculpture, surrounded by palm trees and a clear blue sky.

Hurricane Monument

8.6/10 (250 reviews)
The memories of those lost to the 1935 Labor Day Hurricane live on at this moving tribute and burial site along the Overseas Highway.
See properties
A church sign with the name Matecumbe United Methodist Church, listing Sunday School and Worship Service times.

Matecumbe United Methodist Church

8.2/10 (18 reviews)
After visiting Matecumbe United Methodist Church, make a plan to see the other sights and activities in Islamorada. Discover the beautiful sunsets in this family-friendly area, or enjoy its fishing spots.
See properties
A colorful building with a sign reading "Florida Keys Brewing Co." and a Santa Claus decoration.

Florida Keys Brewing Co.

9.2/10 (520 reviews)
You can take time to visit Florida Keys Brewing Co. during your travels to Islamorada.
See properties

Lorelei Restaurant & Cabana Bar

After visiting Lorelei Restaurant & Cabana Bar, make a plan to see the other sights and activities in Islamorada.
See properties

Islamorada Brewery & Distillery

9.4/10 (8 reviews)
You can take time to visit Islamorada Brewery & Distillery during your travels to Islamorada.
See properties

MoradaWay Arts & Cultural District

Enjoy an outing to MoradaWay Arts & Cultural District during your stay in Islamorada.
See properties

Frequently asked questions

What's the area like around Panhandle Key?
If you're planning to come to the area to visit Panhandle Key, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, you might search for properties close to public transportation so it's easy to get around.
What's the best place to stay close to Panhandle Key?
Cheeca Lodge & Spa is one of the top choices for your stay based on our traveler data, and this resort offers 3 outdoor pools and a full-service spa. You'll find it 8 mi (12.8 km) from Panhandle Key. Other good choices around the area include Chesapeake Beach Resort and Amara Cay Resort.
If I need to cancel the hotel reservation for my stay near Panhandle Key, will I receive a refund?
Yes! Most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best options available near Panhandle Key.
Where can I learn more about changing or cancelling my trip in the area near Panhandle Key?
For more information about picking new dates or cancelling your stay near Panhandle Key, go to https://www.expedia.com/service/.

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