Find hotels in Matthews, MO from $55
Upfront pricingOur total price for your stay includes taxes and fees
Treat yourselfSave 10% or more on over 100,000 hotels worldwide with Member PricesLearn about One Key
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Matthews
Family friendly
Waterpark
Pet friendly
Apartment
Condo
Check prices for these dates
Tonight
Aug 15 - Aug 16Tomorrow
Aug 16 - Aug 17Next weekend
Aug 21 - Aug 23In two weeks
Aug 28 - Aug 30Our top choices for Matthews hotels
1. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
Brandi
$98 nightly
$110 total
Aug 23 - Aug 24
Total with taxes and fees
2. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
michael
$100 nightly
$113 total
Aug 23 - Aug 24
Total with taxes and fees
3. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
Sally
$94 nightly
$108 total
Aug 23 - Aug 24
Total with taxes and fees
4. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Joni
$101 nightly
$114 total
Aug 23 - Aug 24
Total with taxes and fees
5. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
Lauren
$109 nightly
$123 total
Aug 23 - Aug 24
Total with taxes and fees
6. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
Kevin
$90 nightly
$103 total
Aug 16 - Aug 17
Total with taxes and fees
7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
Sharika West
$56 nightly
$64 total
Aug 16 - Aug 17
Total with taxes and fees
8. Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
Starlette
$94 nightly
$107 total
Aug 23 - Aug 24
Total with taxes and fees
9. Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
James
$63 nightly
$72 total
Aug 16 - Aug 17
Total with taxes and fees
10. Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
Chevayon
$64 nightly
$73 total
Sep 13 - Sep 14
Total with taxes and fees
11. Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
William
$59 nightly
$67 total
Sep 10 - Sep 11
Total with taxes and fees
12. Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
Temera
$66 nightly
$75 total
Aug 16 - Aug 17
Total with taxes and fees
13. The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
Bobby
$66 nightly
$74 total
Sep 7 - Sep 8
Total with taxes and fees
14. Travel Inn Marston I-55 by Hotel O
Travel Inn Marston I-55 by Hotel OMarston
Riley
$55 nightly
$63 total
Sep 15 - Sep 16
Total with taxes and fees
15. Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
Vanessa
$98 nightly
$110 total
Aug 22 - Aug 23
Total with taxes and fees
16. Eagle Inn Charleston
Eagle Inn CharlestonCharleston
Jackson
$69 nightly
$77 total
Aug 16 - Aug 17
Total with taxes and fees
17. Travelodge by Wyndham Dexter
Travelodge by Wyndham DexterDexter
Steven
$86 nightly
$96 total
Aug 20 - Aug 21
Total with taxes and fees
18. Dexter Inn
Dexter InnDexter
Cynthia
$58 nightly
$65 total
Aug 23 - Aug 24
Total with taxes and fees
19. Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
France
$60 nightly
$66 total
Aug 16 - Aug 17
Total with taxes and fees
20. Econo Lodge Dexter
Econo Lodge DexterDexter
Herman
$49 nightly
$55 total
Sep 14 - Sep 15
Total with taxes and fees
Where to stay near Matthews
Matthews, Missouri offers a charming escape for outdoor enthusiasts and romantics alike. Enjoy the breathtaking scenery on a leisurely hike or indulge in family-friendly adventures nearby. With its welcoming atmosphere, Matthews promises a relaxing getaway filled with memorable excursions and friendly faces.
Photo by Ryan Coleman
Sikeston
Discover Sikeston, a welcoming destination perfectly suited for travelers looking for a blend of business, family fun, and outdoor adventures. With highlights like the Sikeston Depot Museum and the Central Park, visitors can enjoy cultural experiences and relaxing green spaces. The nearby lake and national state park offer breathtaking nature escapes. Located about 9 miles by car from Matthews, Sikeston is a smart choice for a hotel stay, providing easy access to both adventure and leisure.
Canalou
Experience the charm of Canalou, a great hub for family-oriented travelers looking to connect with nature and enjoy budget-friendly adventures. This inviting city is just 6 miles from Matthews, offering easy access to delightful attractions like the Sikeston Depot Museum, Central Park, and the City of Miner Convention Center. With a welcoming atmosphere year-round, Canalou makes an excellent choice for those eager to explore scenic landscapes and outdoor activities. Choose Canalou for your stay and discover a relaxing getaway that feels like home.
Morehouse
Family travelers will love Morehouse, known for its welcoming atmosphere and access to delightful attractions. Explore the Sikeston Depot Museum for a taste of local history, enjoy the lush surroundings of Central Park, or host events at the City of Miner Convention Center. With visitor numbers peaking in the summer months, Morehouse offers a vibrant experience year-round. Located about 8 miles from Matthews, it’s an ideal spot for budget-friendly accommodations that ensure a memorable stay.
Photo by Ryan Coleman
Miner
Ideally situated for families and nature lovers, Miner offers a delightful escape near Matthews, Missouri. Visitors can explore the City of Miner Convention Center for events, immerse themselves in the rich history at the Sikeston Depot Museum, or unwind at Central Park’s scenic beauty. With only about a 10-mile drive from Matthews, getting to Miner is easy and hassle-free. Choosing Miner for your stay ensures a memorable blend of culture, outdoor experiences, and budget-friendly options.
Baker
Travelers visiting the area often choose Baker, particularly families and nature enthusiasts seeking a vibrant experience. This charming city offers a delightful blend of attractions, including the Sikeston Depot Museum, the Dexter Welcome Center Depot and Museum, and The Heritage House, perfect for discovering art, history, and local heritage. With a steady flow of visitors year-round, Baker is conveniently located about 10 miles from Matthews, making it an excellent choice for your next vacation stay.
Stay near popular attractions around Matthews
Matthews offers a charming blend of outdoor beauty and cultural experiences, perfect for romantic getaways or family adventures. Explore scenic landscapes, vibrant arts centers, and engaging museums that will enrich your stay and create lasting memories. Enjoy the allure of this delightful destination!
Sikeston Depot Museum
7.6/10 (57 reviews)
Experience the best of culture at the Sikeston Depot Museum, perfect for art lovers and history buffs. This vibrant museum showcases local heritage and artistic expression, offering a unique glimpse into the region's past. It's about a 9-mile drive from Matthews, making it an easy stop during your visit.
Central Park
7.2/10 (56 reviews)
Often cited as a favorite for families, Central Park in Sikeston offers a delightful blend of outdoor activities and city vibes. Located about 8 miles by car from Matthews, it’s an ideal spot for a quick visit, making it easy to enjoy a memorable day out in nature.
New Madrid Historical Museum
8.2/10 (36 reviews)
Ideal for travelers interested in history, the New Madrid Historical Museum offers a fascinating glimpse into the area's rich cultural heritage. Located about 12 miles from Matthews, this museum showcases the history and significance of New Madrid, making it a convenient stop for those exploring the region.
Hunter-Dawson State Historic Site
7.6/10 (13 reviews)
The perfect starting point for history buffs, Hunter-Dawson State Historic Site offers a glimpse into Missouri's rich cultural heritage. Located about 12 miles from Matthews, this historic house showcases beautifully preserved architecture and unique stories. Staying nearby allows easy access to this fascinating landmark.
Marston Community Center
Discover the appeal of the Marston Community Center, a vibrant arts hub ideal for culture seekers visiting Matthews, Missouri. Located about 17 miles by car from Matthews, this center offers an engaging atmosphere where you can immerse yourself in local art and community events, making it a convenient stop during your stay.
Big Oak Tree State Park
8.0/10 (20 reviews)
Enjoy the simplicity of Big Oak Tree State Park, a haven for outdoor lovers seeking adventure and stunning scenery. Located about 18 miles from Matthews, this park offers lush landscapes and unique natural features, making it an ideal spot for a relaxing getaway. Staying nearby allows easy access to its natural beauty.
Front Street Studio & Art Gallery
8.6/10 (15 reviews)
Perfectly suited for art lovers, Front Street Studio & Art Gallery in Blodgett, Missouri, offers a vibrant cultural experience with unique artworks that reflect local talent. Located about 17 miles from Matthews, it's an inviting destination for those looking to immerse themselves in the region's artistic scene, making it a convenient stop on your travels.
City of Miner Convention Center
A stellar choice for business travelers, the City of Miner Convention Center offers a professional atmosphere for conferences and events. Located about 10 miles by car from Matthews, it provides easy access for attendees. Staying nearby ensures you’re close to a hub of business activity.
Top Matthews Hotel Reviews
Hampton Inn By Hilton Dexter
10/10 Excellent
"The staff was all very nice and friendly. The room was very nice and clean. Air worked good. Parking right next to hotel. They had a good breakfast. We will definitely stay there again."
Days Inn and Suites by Wyndham Sikeston
8/10 Good
"Very spacious suite. Fit our needs very well."
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
10/10 Excellent
"I was there on a business trip during the Boot Heel Rodeo. Sikeston was packed. Staff helped me with my printing and got down on their hand and knees to find my phone which turned up in my car. Great customer service and WiFi and everything worked perfectly!"
Super 8 by Wyndham Sikeston/Miner Area
8/10 Good
"the room was a time warp to the 1970's, the clerk was as helpful as flo from monsters inc and i find it shady they have a request to pay the room deposit in cash for quicker reimbursement. its next to a mcdonalds and the free way so quick eat and jet possibility but it was clean the water was hot and it didnt smell of old dogs so for what it was it was ok"
Fairfield Inn & Suites by Marriott Sikeston
10/10 Excellent
"Staff were excellent! Very personable with us!"
The Riverstone Hotel Charleston-Sikeston
8/10 Good
"The ad and picture for the hotel is a little deceiving. It shows a large fountain in front of the front lobby. There was none. This is the former Quality Inn Hotel was not good at all. The hotel has been cleaned up and rebranded. The room was nice. My only concern was all the bugs that were outside the room door and flew into the room when you opened your door at night. The other thing that I did not like was the surprise $100 fee that I had to pay up front for potential damage to the room. This fee was returned during check out."
Hampton Inn Sikeston
8/10 Good
"Hotel was nice but unfortunately someone decided to smoke in the elevator one night which made it shut down. So, until the repair was completed, everyone one the upper floors had to take the stairs down multiple floors. Usually not that big of an issue, but we were there for a bike ride and had to carry our bikes down three floors in the morning. Thankfully the elevator was fixed by the time we got back. Not really anything the hotel or staff caused, but just repercussions from the act of one person doing something stupid! We will definitely stay here again"
Super 8 by Wyndham Charleston/Sikeston East MO
10/10 Excellent
"Nice staff. Very accommodating."
Dexter Inn
10/10 Excellent
"Clean room clean bathroom and nice staff"
More cheap stays in Matthews
Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
$59 nightly
$65 total
Aug 23 - Aug 24
Total with taxes and fees
6.6/10 (657 reviews)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
$64 nightly
$73 total
Sep 13 - Sep 14
Total with taxes and fees
7.2/10 Good! (1,001 reviews)
Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
$90 nightly
$103 total
Aug 16 - Aug 17
Total with taxes and fees
8.4/10 Very Good! (1,011 reviews)
Hampton Inn By Hilton Dexter
2179 Gill Plaza Drive Dexter MO
$98 nightly
$110 total
Aug 22 - Aug 23
Total with taxes and fees
9.6/10 Exceptional! (63 reviews)
Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
$98 nightly
$110 total
Aug 23 - Aug 24
Total with taxes and fees
9/10 Wonderful! (607 reviews)
Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
$100 nightly
$113 total
Aug 23 - Aug 24
Total with taxes and fees
Hotels in Matthews with star-rating
3 Star Hotels
4 properties
2 Star Hotels
20 properties
Frequently asked questions
Explore a world of travel with Expedia
- Hotels with Balconies in Sikeston
- Malden Hotels
- Wyndham Hotels in Sikeston
- Hotels with smoking rooms in Sikeston
- Romantic Hotels in Sikeston
- Marston Hotels
- Apartments in Sikeston
- Casino Hotels in Sikeston
- Hotels with Connecting Rooms in Sikeston
- Sikeston Hotels
- Rv Parks in Morehouse
- Miner Hotels
- Gideon Hotels
- Hotels with Kitchenettes in Sikeston
- Bertrand Hotels
- Hotels with Suites in Sikeston
- Family Hotels in Sikeston
- Hotels & Resorts for Couples in Sikeston
- Portageville Hotels
- Hotels with Tennis Courts in Sikeston
- Historic Hotels in Sikeston
- Oran Hotels
- Bernie Hotels
- Hotels with Restaurants in Sikeston
- Hotels with Laundry Facilities in Sikeston
- Hotels with Free Breakfast in Sikeston
- Commerce Hotels
- Cape Girardeau Hotels
- 4 Star Hotels in Sikeston
- East Prairie Hotels
- Blodgett Hotels
- Hotels with Hot Tubs in Sikeston
- Pet-Friendly Hotels in Sikeston
- Dexter Hotels
- Resorts in Sikeston
- Cabin Rentals in Sikeston
- Campbell Hotels
- Vacation Homes in Sikeston
- Resorts & Hotels with Spas in Sikeston
- Hotel Wedding Venues Hotels in Sikeston
- Morley Hotels
- Benton Hotels
- Hotels with an Outdoor Pool in Sikeston
- Risco Hotels
- Hotels near River Ridge Winery
- Luxury Hotels in Sikeston
- Advance Hotels
- Gay friendly Hotels in Sikeston
- Extended Stay Hotels in Sikeston
- Hotels with Bars in Sikeston
- Canalou Hotels
- Chaffee Hotels
- Hotels near Big Oak Tree State Park
- Charleston Hotels
- Cheap Hotels in Sikeston
- Hayti Hotels
- Motels in Matthews
- New Madrid Hotels
- Poplar Bluff Hotels
- Hotels with a Pool in Sikeston
- B&B in Sikeston
- Hotels near Malden Regional
- Hotels with an Indoor Pool in Sikeston
- Motels in Sikeston
- Hotels near Hunter-Dawson State Historic Site
- 3 Star Hotels in Sikeston
- Bloomfield Hotels
- Flights from Sikeston Memorial Municipal
- Flights to Sikeston
- Flights from Memphis (MEM) to Sikeston (SIK)
- Flights from Morehouse
- Flights from Los Angeles (LAX) to Sikeston (SIK)
- Flights from Houston (IAH) to Sikeston (SIK)
- Flights from Detroit (DTW) to Sikeston (SIK)
- Flights from Chicago (ORD) to Sikeston (SIK)
- Flights from New Orleans (MSY) to Sikeston (SIK)
- Flights from Cape Girardeau (CGI) to Sikeston (SIK)
- Flights from Cape Girardeau Municipal
- Flights from Philadelphia (PHL) to Sikeston (SIK)
- Flights from Nashville (BNA) to Sikeston (SIK)
- Flights from Dallas (DFW) to Sikeston (SIK)
- Flights from Minneapolis (MSP) to Sikeston (SIK)
- Flights from Sikeston
- Hertz Rental Cars in Sikeston
- First Car Rental Rental Cars in Sikeston
- Car rentals near Central Park
- Budget Rental Cars in Sikeston
- Firefly Cyprus Rental Cars in Sikeston
- Avis Rental Cars in Sikeston
- National Car Rental Rental Cars in Sikeston
- Convertible Car Rentals in Sikeston
- Enterprise Rental Cars in Sikeston
- Van Car Rentals in Sikeston
- Car rental Sikeston
- Dollar Rent A Car Rental Cars in Sikeston
