Title: Top Mississippi County Hotels: 2026 Best Hotels in Mississippi County - Expedia.com [Vacation Rentals in Mississippi County](https://expedia.com/Destinations-In-Mississippi-County.d553248635976432543.Vacation-Rental-Destinations)[Mississippi County Flights](https://expedia.com/Destinations-In-Mississippi-County.d553248635976432543.Flight-Destinations)[Car Rentals in Mississippi County](https://expedia.com/Destinations-In-Mississippi-County.d553248635976432543.Car-Rental-Destinations)[Mississippi County Vacations](https://expedia.com/Mississippi-County.d553248635976432543.Destination-Travel-Guides) ![Hernando de Soto Bridge over the Mississippi River Memphis. It separates Tennessee from Arkansas, United States of America.](https://images.trvl-media.com/place/553248635976432543/a415ea8a-3196-45f9-80cd-79b265986557.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635976432543/a415ea8a-3196-45f9-80cd-79b265986557.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Mississippi County ![Really neat architecture! ](https://images.trvl-media.com/place/6058418/f75b8769-1e2b-4f05-8eee-e2245da6bc80.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Blytheville [](https://expedia.com/Blytheville-Hotels.d6058418.Travel-Guide-Hotels) ![Freight barge carrying cargo on Mississippi river, and Hernando deSoto bridge in Memphis, TN, USA](https://images.trvl-media.com/place/9048/a794aed8-86cd-4914-b7f8-daaf42ac360b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Osceola [](https://expedia.com/Osceola-Hotels.d9048.Travel-Guide-Hotels) ![The movie Walk the Line was filmed here. ](https://images.trvl-media.com/place/553248635458706086/4e55dfb4-2868-49e3-a26d-ad99384ad470.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Dyess [](https://expedia.com/Dyess-Hotels.d553248635458706086.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Mar 6 - Mar 7](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-03-06&endDate=2026-03-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 7 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-03-07&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mississippi County hotels ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/89abfba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/w3840h2158x0y0-52160e0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/ff17346b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/33099aea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Osceola by IHG [](https://www.expedia.com/Osceola-Hotels-Holiday-Inn-Osceola-By-Ihg.h114380079.Hotel-Information) Osceola 8.8/10 Excellent (22 reviews) "Staff was courteous. Clean rooms. Restaurant was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adrian $118 nightly $136 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Osceola-Hotels-Holiday-Inn-Osceola-By-Ihg.h114380079.Hotel-Information) ![Indoor pool, seasonal outdoor pool, open 7 AM to 10 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/77afceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/bd4e7635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/ccab0c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/a8aa83eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Blytheville by IHG [](https://www.expedia.com/Blytheville-Hotels-Holiday-Inn-Blytheville.h3357.Hotel-Information) Blytheville 8.4/10 Very Good (669 reviews) "Spotless, great shower, comfy beds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandi $122 nightly $138 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Holiday-Inn-Blytheville.h3357.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/05343fb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/d69e7fe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queens | In-room safe, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/29810e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/b4d3f15c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Blytheville [](https://www.expedia.com/Blytheville-Hotels-Hampton-Inn-Blytheville.h41712.Hotel-Information) Blytheville 9.2/10 Wonderful (905 reviews) "Clean room friendly staff good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $107 nightly $121 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Hampton-Inn-Blytheville.h41712.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/9e3a6143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/54184826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/1f2bbf62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/a88b7932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Blytheville [](https://www.expedia.com/Blytheville-Hotels-Comfort-Inn-Suites.h2032178.Hotel-Information) Blytheville 8.6/10 Excellent (710 reviews) "This was a nice place to stay. Would recommend it to all." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina $102 nightly $116 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Comfort-Inn-Suites.h2032178.Hotel-Information) ![Louis 3 Bedroom Cottage A | Private kitchen | Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/4161dd61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Louis 3 Bedroom Cottage A | Private kitchen | Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/f1e262e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/a7d05be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/2473875f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Louis Hotel [](https://www.expedia.com/Wilson-Hotels-The-Louis-Hotel.h93829832.Hotel-Information) Wilson 9.6/10 Exceptional (56 reviews) "The staff was extremely courteous and the room was so beautiful and clean. I would LOVE to stay there again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexa $201 nightly $226 total Mar 29 - Mar 30 Total with taxes and fees [](https://www.expedia.com/Wilson-Hotels-The-Louis-Hotel.h93829832.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/37e98bca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/c1c85af2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Down comforters, pillowtop beds, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/0a823310.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/12fcc0a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Suites & Studios Blytheville by Sonesta [](https://www.expedia.com/Blytheville-Hotels-Americas-Best-Value-Inn-Blytheville.h1226644.Hotel-Information) Blytheville 6.8/10 (429 reviews) "Nice staff helpful, clean rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deepak $68 nightly $77 total Mar 11 - Mar 12 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Americas-Best-Value-Inn-Blytheville.h1226644.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/6e8f6961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/809a1013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/927574bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/d5c1715d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Osceola AR [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-Suites-By-Wyndham-Osceola-AR.h41676.Hotel-Information) Osceola 6.4/10 (374 reviews) "One of the worst motels I have stayed at in years" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary $64 nightly $74 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-Suites-By-Wyndham-Osceola-AR.h41676.Hotel-Information) ![Room, 2 Double Beds, Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/dddaf316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/1fa5848b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/4f0c811a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/6b6b4e27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deerfield Inn By Capital O Blytheville AR I55 [](https://www.expedia.com/Blytheville-Hotels-Deerfield-Inn-By-Capital-O-Blytheville-AR-I55.h87916825.Hotel-Information) Blytheville 7.4/10 Good (63 reviews) "Room is clean, sheets have been changed, staff people are nice and attentive " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina $61 nightly $68 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Deerfield-Inn-By-Capital-O-Blytheville-AR-I55.h87916825.Hotel-Information) ![Single Room | Blackout drapes, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/ba85d102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/8cd0affc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | Blackout drapes, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/be90deef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/e5685d98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairview Suites [](https://www.expedia.com/Blytheville-Hotels-Fairview-Suites.h121062570.Hotel-Information) Blytheville 7.0/10 Good (15 reviews) "Good place to stay for blue collar workers " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott $52 nightly $60 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Fairview-Suites.h121062570.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/beb06494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/db885cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Accessible, Refrigerator | Bathroom | Combined shower/tub, eco-friendly toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/1b27c316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/5ebfc8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Blytheville [](https://www.expedia.com/Blytheville-Hotels-Super-8-By-Wyndham-Blytheville.h9746.Hotel-Information) Blytheville 6.0/10 (528 reviews) "I really enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara $58 nightly $66 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Super-8-By-Wyndham-Blytheville.h9746.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/c6c2c410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/9b00666e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/825e07c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/e062d642.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Roadside Inn [](https://www.expedia.com/Osceola-Hotels-Roadside-Inn.h76930021.Hotel-Information) Osceola 7.6/10 Good (24 reviews) "Room temperature was great even when we first walked in. Very clean, comfortable and nice. Staff was very friendly and polite. Sure wish they had a coffee pot in the room. Other than that everything was great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicky $53 nightly $61 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Osceola-Hotels-Roadside-Inn.h76930021.Hotel-Information) ![Business center](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/ce00ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/0fd71e28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/1ece02d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/78179eba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Blytheville [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-By-Wyndham-Blytheville.h20128.Hotel-Information) Blytheville 5.8/10 (384 reviews) "Very clean, very accommodating! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason $61 nightly $69 total Mar 28 - Mar 29 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-By-Wyndham-Blytheville.h20128.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/4746c4b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/22d67d8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/6034c339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/347725ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Blytheville [](https://www.expedia.com/Blytheville-Hotels-Quality-Inn-Blytheville-I-55.h15679.Hotel-Information) Blytheville 6.6/10 (117 reviews) "Everything was good and the staff was friendly and courteous " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike [](https://www.expedia.com/Blytheville-Hotels-Quality-Inn-Blytheville-I-55.h15679.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/096dfdd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/w921h613x0y0-276c63ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/da5c1fc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/7b08b617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sands Hotel [](https://www.expedia.com/Blytheville-Hotels-Sands-Hotel.h120547558.Hotel-Information) Blytheville 2.0/10 (1 review) $45 nightly $51 total Mar 21 - Mar 22 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Sands-Hotel.h120547558.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/8eb6cdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels, soap, toilet paper](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/226e521f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/2826de7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/301a133d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquil 2-bedroom house with AC in charming Blytheville [](https://www.expedia.com/Blytheville-Hotels-Tranquil-2-Bedroom-House-With-AC-In-Charming-Blytheville.h122917109.Hotel-Information) Blytheville 6.0/10 (3 reviews) "All the pipes were frozen" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wendy H. $273 nightly $307 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Tranquil-2-Bedroom-House-With-AC-In-Charming-Blytheville.h122917109.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/5b8972f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/40f6e371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/eac776b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/f88a4262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mahase Guest House at The Refuge [](https://www.expedia.com/Mahase-Guest-House-At-The-Refuge.h111531448.Hotel-Information) Osceola 10/10 Exceptional (2 reviews) "Great place to stay! Quiet place and not too far from restaurants and market. Enjoyed the comfortable bed and the nice size kiitchen. I would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex b. [](https://www.expedia.com/Mahase-Guest-House-At-The-Refuge.h111531448.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/4fcfe311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/d5e7ae42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/7a745300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/aa22f4cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wright Way Oasis. 3-bedroom house 2 bath with a fitness room, Wi-Fi an Smart Tv [](https://www.expedia.com/Blytheville-Hotels-Wright-Way-Oasis-3-Bedroom-House1-Bath-With-A-Fitness-Room.h112808687.Hotel-Information) Blytheville 8.8/10 Excellent (9 reviews) "The beds are very comfortable. Overall we felt it was a safe place to stay. Host was attentive and accommodating to our needs. Spacious for 9 women to stay in. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mi F. $285 nightly $321 total Mar 8 - Mar 9 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Wright-Way-Oasis-3-Bedroom-House1-Bath-With-A-Fitness-Room.h112808687.Hotel-Information) ![Premium Room, 2 Double Beds, Kitchenette | Room amenity](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/98d458b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds, Kitchenette | Private kitchenette | Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/61bc760e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 1 King Bed, Kitchenette | Private kitchenette | Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/dc1779cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds, Kitchenette | Private kitchen | Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/d45c4f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hotel Blytheville AR I-55 [](https://www.expedia.com/Blytheville-Hotels-OYO-Hotel-Blytheville-AR-Hwy-61.h23397288.Hotel-Information) Blytheville 3.8/10 (130 reviews) "Cleanliness, staff & service, property conditions & facilities, room comfort, everything is excellent. Loved and enjoyed the stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark [](https://www.expedia.com/Blytheville-Hotels-OYO-Hotel-Blytheville-AR-Hwy-61.h23397288.Hotel-Information) ![Dishwasher, toaster](https://images.trvl-media.com/lodging/112000000/111760000/111753600/111753521/54e5e6b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111760000/111753600/111753521/da4a91cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111760000/111753600/111753521/55978475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111760000/111753600/111753521/29ebd25f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Delta House - CHARMING 3 BED. HOUSE W/DECK & GRILL, VERY CLEAN! [](https://www.expedia.com/Blytheville-Hotels-The-Delta-House-CHARMING-3-BED-HOUSE-WDECK-GRILL.h111753521.Hotel-Information) Blytheville 9.4/10 Exceptional (3 reviews) "Excellent host, very accommodating, and clean. Have stayed at multiple properties this host owns and would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael F. [](https://www.expedia.com/Blytheville-Hotels-The-Delta-House-CHARMING-3-BED-HOUSE-WDECK-GRILL.h111753521.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/d34a5a6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/7c6132b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/deeb824c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/9cf1d3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3 bedrooms, 2 full bath, dining room, great room, den, beautiful outdoor patio. [](https://www.expedia.com/Blytheville-Hotels-3-Bedrooms.h97150528.Hotel-Information) Blytheville 10/10 Exceptional (16 reviews) "Perfect place for my crew and i to spend the week." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David M. [](https://www.expedia.com/Blytheville-Hotels-3-Bedrooms.h97150528.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-21&endDate=2026-03-22®ionId=553248635976432543&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248635976432543) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-County.d553248635976432543.Hotel-Destinations)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-County.d553248635976432543.Hotel-Destinations) ## Top Mississippi County Hotel Reviews ![Hu. Hotel](https://images.trvl-media.com/lodging/1000000/810000/807600/807514/240adf57_y.jpg) ### Hu. Hotel 10/10 Excellent "Very nice hotel!!! One of the best ones i've been to in a while. Nice, clean rooms!!! Oh and the penthouse has a bar." [](https://expedia.com/Memphis-Hotels-Hu-Hotel.h807514.Hotel-Information) ![The Stallion](https://images.trvl-media.com/lodging/111000000/110410000/110403300/110403215/10dc605d_y.jpg) ### The Stallion 10/10 Excellent "Every aspect of the home met my needs. My experience could not have been any better!!!! Thank You " [](https://expedia.com/Memphis-Hotels-The-Stallion.h110403215.Hotel-Information) ![Memphis Riverline Hotel](https://images.trvl-media.com/lodging/1000000/10000/900/821/758cde45_y.jpg) ### Memphis Riverline Hotel 8/10 Good "We had a nice time staying here, easy to Uber to Beale street. The hotel staff were great. Great service at the bar/restaurant. The valet parking was very easy and we could see our vehicle from the lobby. The old elevator was really cool, however; we did get stuck for a brief moment as the doors did not open (just one time) . Across from the event center so that was very convenient since we were there for work." [](https://expedia.com/Memphis-Hotels-Sheraton-Memphis-Downtown-Hotel.h821.Hotel-Information) ![The Peabody Memphis](https://images.trvl-media.com/lodging/1000000/20000/15600/15502/c3f81189_y.jpg) ### The Peabody Memphis 10/10 Excellent "Beautiful hotel, great location. " [](https://expedia.com/Memphis-Hotels-The-Peabody-Memphis.h15502.Hotel-Information) ![La Quinta Inn & Suites by Wyndham West Memphis](https://images.trvl-media.com/lodging/35000000/34580000/34578000/34577952/b94559ee_y.jpg) ### La Quinta Inn & Suites by Wyndham West Memphis 10/10 Excellent "We always stay here on our trip to Austin, TX. Halfway from Toledo, OH to Austin. Great breakfast, rooms are clean and very comfy. That's about all we're looking for. Highly recommend." [](https://expedia.com/West-Memphis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-West-Memphis.h34577952.Hotel-Information) ![Southland Casino Hotel](https://images.trvl-media.com/lodging/83000000/82950000/82940100/82940076/277b7353_y.jpg) ### Southland Casino Hotel 10/10 Excellent "Always love going to this hotel. Wish I won at the casino though. lol" [](https://expedia.com/Memphis-Hotels-Southland-Casino-Racing.h82940076.Hotel-Information) ![Hyatt Centric Beale Street Memphis](https://images.trvl-media.com/lodging/63000000/63000000/62999300/62999249/a29c606e_y.jpg) ### Hyatt Centric Beale Street Memphis 2/10 Terrible "Overpriced. The staff was rude and the room was dirty. Shower had hair and stains inside." [](https://expedia.com/Memphis-Hotels-Hyatt-Centric-Beale-Street-Memphis.h62999249.Hotel-Information) ![Big Cypress Lodge](https://images.trvl-media.com/lodging/13000000/13000000/12993400/12993388/d7eafe81_y.jpg) ### Big Cypress Lodge 10/10 Excellent "Staff was very friendly " [](https://expedia.com/Memphis-Hotels-Big-Cypress-Lodge.h12993388.Hotel-Information) ![Hampton Inn & Suites Memphis-Beale Street](https://images.trvl-media.com/lodging/1000000/460000/456300/456281/63dba140_y.jpg) ### Hampton Inn & Suites Memphis-Beale Street 10/10 Excellent "N/A" [](https://expedia.com/Memphis-Hotels-Hampton-Inn-Suites-Memphis-Beale-Street.h456281.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Mississippi County - [Blytheville Hotels ](https://expedia.com/Blytheville-Hotels.d6058418.Travel-Guide-Hotels) - [Osceola Hotels ](https://expedia.com/Osceola-Hotels.d9048.Travel-Guide-Hotels) - [Wilson Hotels ](https://expedia.com/Wilson-Hotels.d553248635458701109.Travel-Guide-Hotels) - [Manila Hotels ](https://expedia.com/Manila-Hotels.d553248634999080581.Travel-Guide-Hotels) - [Joiner Hotels ](https://expedia.com/Joiner-Hotels.d553248634999254953.Travel-Guide-Hotels) - [Leachville Hotels ](https://expedia.com/Leachville-Hotels.d3000343188.Travel-Guide-Hotels) - [Dyess Hotels ](https://expedia.com/Dyess-Hotels.d553248635458706086.Travel-Guide-Hotels) - [Dell Hotels ](https://expedia.com/Dell-Hotels.d553248635975876297.Travel-Guide-Hotels) - [Luxora Hotels ](https://expedia.com/Luxora-Hotels.d553248635975867783.Travel-Guide-Hotels) - [Burdette Hotels ](https://expedia.com/Burdette-Hotels.d553248635975868572.Travel-Guide-Hotels) - [Etowah Hotels ](https://expedia.com/Etowah-Hotels.d6341249.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Johnny Cash House ](https://expedia.com/Johnny-Cash-House-Hotels.0-l553248621532648013-0.Travel-Guide-Filter-Hotels) - [Hotels near Delta Gateway Museum ](https://expedia.com/Delta-Gateway-Museum-Hotels.0-l553248634328751079-0.Travel-Guide-Filter-Hotels) - [Hotels near Arkansas Northeastern College ](https://expedia.com/Arkansas-Northeastern-College-Hotels.0-l6239816-0.Travel-Guide-Filter-Hotels) - [Hotels near Lights of the Delta ](https://expedia.com/Lights-Of-The-Delta-Hotels.0-l6274731-0.Travel-Guide-Filter-Hotels) - [Hotels near Arkansas Aeroplex ](https://expedia.com/Arkansas-Aeroplex-Hotels.0-l6274726-0.Travel-Guide-Filter-Hotels) - [Hotels near Riverlawn Country Club ](https://expedia.com/Riverlawn-Country-Club-Hotels.0-l553248635974650924-0.Travel-Guide-Filter-Hotels) - [Hotels near Walker Park ](https://expedia.com/Walker-Park-Hotels.0-l6239818-0.Travel-Guide-Filter-Hotels) - [Hotels near Thunder Bayou Golf Links ](https://expedia.com/Thunder-Bayou-Golf-Links-Hotels.0-l6239820-0.Travel-Guide-Filter-Hotels) - [Hotels near Hampson Archeological Museum State Park ](https://expedia.com/Hampson-Archeological-Museum-State-Park-Hotels.0-l553248621532648014-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Mississippi County - [Vacation Homes in Mississippi County ](https://expedia.com/Mississippi-County-Private-Vacation-Homes.d553248635976432543-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Mississippi County ](https://expedia.com/Mississippi-County-Apartments.d553248635976432543-aaApartments.Travel-Guide-Accommodation) - [Motels in Mississippi County ](https://expedia.com/Mississippi-County-Motels.d553248635976432543-aaMotels.Travel-Guide-Accommodation) - [Condo Rentals in Mississippi County ](https://expedia.com/Mississippi-County-Condos.d553248635976432543-aaCondos.Travel-Guide-Accommodation) - [Cottages in Mississippi County ](https://expedia.com/Mississippi-County-Cottages.d553248635976432543-aaCottages.Travel-Guide-Accommodation) - [Farmstay in Mississippi County ](https://expedia.com/Mississippi-County-Agritourism.d553248635976432543-aaAgritourism.Travel-Guide-Accommodation) - [Villas in Mississippi County ](https://expedia.com/Mississippi-County-Villas.d553248635976432543-aaVillas.Travel-Guide-Accommodation) - [Aparthotels in Mississippi County ](https://expedia.com/Mississippi-County-Apart-Hotels.d553248635976432543-aaApartHotels.Travel-Guide-Accommodation) - [Guest Houses in Mississippi County ](https://expedia.com/Mississippi-County-Guest-Houses.d553248635976432543-aaGuestHouses.Travel-Guide-Accommodation) - [Cabin Rentals in Mississippi County ](https://expedia.com/Mississippi-County-Cabins.d553248635976432543-aaCabins.Travel-Guide-Accommodation) - [B&B in Mississippi County ](https://expedia.com/Mississippi-County-Bed-And-Breakfast.d553248635976432543-aaBedAndBreakfast.Travel-Guide-Accommodation) ### Hotels near Mississippi County Airports - [Memphis Intl. 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