A valley with a town nestled between hills, a winding road, and distant mountains.

Santee Vacation Rentals

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Check prices for these dates

In two weeks
Sep 4 - Sep 6
In two months
Oct 16 - Oct 18
In three months
Nov 13 - Nov 15
In four months
Dec 11 - Dec 13

Our top choices for Santee vacation rentals

1 bedroom, iron/ironing board, WiFi, bed sheets

1. Cozy Private Studio in El Cajon

Cozy Private Studio in El Cajon
Mount Helix
9.0 out of 10, Wonderful, (27 reviews)
"It was a great plead to stay"
United States
Simon
$146 nightly
The price is $146
Aug 19 - Aug 20
Total with taxes and fees
Cozy Private Studio in El Cajon
Lobby

2. Queen Bed Non-Smoking

Queen Bed Non-Smoking
San Diego CA
10.0 out of 10, Exceptional, (100 reviews)
"Just right for sleeping after sightseeing all day, glad I chose this place over others nearby based on price/availability combo!"
United States
Anonymous traveler
$66 nightly
The price is $72
Aug 23 - Aug 24
Total with taxes and fees
Queen Bed Non-Smoking
1 bedroom, WiFi (free), bed sheets

3. Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry

Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry
Mid-City
10.0 out of 10, Exceptional, (4 reviews)
"Our stay was lovely at Neric's place. Nice decor, clean, comfortable, & quiet. The AC worked well to keep the home at the perfect temp for us. We will stay here again!"
United States
Katherine S.
$175 nightly
The price is $175
Sep 9 - Sep 10
Total with taxes and fees
Splendid 1-bedroom apartment in delightful La Mesa with AC and Laundry
Outdoor pool

4. The Outside Inn at The Tipsy Goat Ranch

The Outside Inn at The Tipsy Goat Ranch
Lakeside
10.0 out of 10, Exceptional, (26 reviews)
"The Outside Inn was absolutely what we needed....relaxing, peaceful, quality time surrounded by beautiful farm animals. The accommodations were very nice and our host, Heather, was lovely. We hope to be back very soon."
United States
Brian F.
$302 nightly
The price is $302
Aug 23 - Aug 24
Total with taxes and fees
The Outside Inn at The Tipsy Goat Ranch
Dining

5. La Mesa Family Retreat - 20 minutes to Beaches & More!

La Mesa Family Retreat - 20 minutes to Beaches & More!
La Mesa
9.0 out of 10, Wonderful, (9 reviews)
"The property was well located for us. "
United States
Ann D.
$574 nightly
The price is $574
Sep 1 - Sep 2
Total with taxes and fees
La Mesa Family Retreat - 20 minutes to Beaches & More!
Lobby sitting area

6. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very Good, (434 reviews)
"Staff were wonderful. Great location."
United States
Benjamin
$97 nightly
The price is $110
Aug 24 - Aug 25
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Private kitchen

7. Lake Murray 3BR Retreat with AC and Skylight

Lake Murray 3BR Retreat with AC and Skylight
La Mesa
10.0 out of 10, Exceptional, (15 reviews)
"Our stay was fantastic and it had everything we need for our 1 week stay. I recommend this location. "
United States
Rosa C.
$309 nightly
The price is $309
Sep 8 - Sep 9
Total with taxes and fees
Lake Murray 3BR Retreat with AC and Skylight
Dining

8. Sunnyside Resort Spa, Beach, Zoo, Arcade

Sunnyside Resort Spa, Beach, Zoo, Arcade
La Mesa
9.6 out of 10, Exceptional, (22 reviews)
"The place is very cozy and beautiful, we stayed there for my son graduation and we had a fabulous time."
United States
Nelta P.
$517 nightly
The price is $517
Aug 20 - Aug 21
Total with taxes and fees
Sunnyside Resort Spa, Beach, Zoo, Arcade
Exterior

9. San Diego Country Estates

San Diego Country Estates
2.5 star property
San Diego Country Estates
9.4 out of 10, Exceptional, (289 reviews)
"Clean rooms, friendly staff"
United States
James
$115 nightly
The price is $122
Aug 20 - Aug 21
Total with taxes and fees
San Diego Country Estates
Terrace/patio

10. Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.8 out of 10, Excellent, (11 reviews)
"The place was as advertised. Comfortable and good privacy in an area that at first glance, didn’t seem like it would have any"
United States
Steve F.
$257 nightly
The price is $286
Aug 19 - Aug 20
Total with taxes and fees
Cozy 2-Bedroom Cottage Near Balboa Park
Interior

11. 3bd with TV and AC, 2 air mattress, 2ba, 15-20 minute to everything in San Diego

3bd with TV and AC, 2 air mattress, 2ba, 15-20 minute to everything in San Diego
Mount Hope
10.0 out of 10, Exceptional, (27 reviews)
"Yes and very close to all the things we wanted to do, extremely clean and extremely well maintained and extras that were nice like bottles of water"
United States
Brent H.
3bd with TV and AC, 2 air mattress, 2ba, 15-20 minute to everything in San Diego
Exterior

12. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
Downtown San Diego
9.4 out of 10, Exceptional, (1,163 reviews)
"Place is clean and beautiful, grear location."
United States
Mabel
$169 nightly
The price is $196
Sep 1 - Sep 2
Total with taxes and fees
Marriott Vacation Club®, San Diego
Smart TV, fireplace, books

13. New Chic & Spacious, Pool, Hot Tub Pristine, Free Park,AC,Hike, Groups

New Chic & Spacious, Pool, Hot Tub Pristine, Free Park,AC,Hike, Groups
San Carlos
10.0 out of 10, Exceptional, (16 reviews)
"It was such a great space to stay for my daughter’s 10th birthday! "
United States
Antoinette M.
$1,085 nightly
The price is $1,208
Sep 15 - Sep 16
Total with taxes and fees
New Chic & Spacious, Pool, Hot Tub Pristine, Free Park,AC,Hike, Groups
Lobby

14. Little Italy Inn - Limited Service Apart Hotel

Little Italy Inn - Limited Service Apart Hotel
2.5 star property
Downtown San Diego
8.2 out of 10, Very Good, (243 reviews)
"Clean rooms, convenient check-in."
United States
Hari
$106 nightly
The price is $122
Aug 19 - Aug 20
Total with taxes and fees
Little Italy Inn - Limited Service Apart Hotel
Property grounds

15. Hilltop cabin with panoramic lake & mountain views

Hilltop cabin with panoramic lake & mountain views
Del Dios
9.6 out of 10, Exceptional, (50 reviews)
"I loved how unique and cute this stay was"
United States
Kayla
$197 nightly
The price is $197
Aug 20 - Aug 21
Total with taxes and fees
Hilltop cabin with panoramic lake & mountain views
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

16. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (191 reviews)
"Enjoyed my stay! Clean spacious room and friendly staff."
United States
omokayode
$168 nightly
The price is $189
Sep 1 - Sep 2
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
Terrace/patio

17. The San Diego Sunrise Adobe

The San Diego Sunrise Adobe
Serra Mesa
10.0 out of 10, Exceptional, (24 reviews)
"Really enjoyed our stay. Everything worked great and communication was great as well. "
United States
Chris B.
$439 nightly
The price is $488
Aug 31 - Sep 1
Total with taxes and fees
The San Diego Sunrise Adobe
Beach nearby, beach towels

18. Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (57 reviews)
"Fantastic place and host especially for the price"
United States
Fayaz J.
$285 nightly
The price is $317
Aug 24 - Aug 25
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!
Terrace/patio

19. Triple Hot Tub Heaven: Fire Pit & Gameroom

Triple Hot Tub Heaven: Fire Pit & Gameroom
Mount Hope
9.6 out of 10, Exceptional, (20 reviews)
"Amazing stay! "
United States
Beto V.
Triple Hot Tub Heaven: Fire Pit & Gameroom
Coffee/tea maker, fridge, microwave, oven

20. Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (106 reviews)
"Amazing stay overall!"
United States
Imany G.
$286 nightly
The price is $318
Sep 1 - Sep 2
Total with taxes and fees
Beautiful Normal Heights Living
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Loews Coronado Bay Resort

Loews Coronado Bay Resort

10/10 Excellent
"Beautiful hotel! Loved the location and amenities"
Natalie 2-night trip
Posted less than an hour ago
Loews Coronado Bay Resort

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $110 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, there are vacation rentals where you'll be just 12.5 mi (20.1 km) from San Diego Zoo, giving you a more secluded option if you want a quieter place to stay. The shops and restaurants are several reasons why visitors like Santee. While you're here, grab a bite or have a drink at the bars.

What are some of the best vacation home rentals in Santee?

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC: Visitors like this Santee vacation home rental. It is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

How many vacation rentals are there in Santee?

Expedia has 5 vacation rentals for your stay in Santee.

What’s there to see and do in Santee?

Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Sportsplex USA Santee and Santee Lakes are a couple of picturesque spots to enjoy the outdoors. San Diego Zoo and Petco Park are other popular places to visit in the area.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can stay in for several days or longer in Santee. Vacation rentals feature extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular choice for families.