Title: Santee Vacation Rentals from $125: Search Short-Term Rentals | Expedia.com

[Santee Travel Guide](https://expedia.com/Santee.dx6678)[Hotels in Santee](https://expedia.com/Santee-Hotels.d6678.Travel-Guide-Hotels)[Flights to Santee](https://expedia.com/Cheap-Flights-To-Santee.d6678.Travel-Guide-Flights)[Things to do in Santee](https://expedia.com/Things-To-Do-In-Santee.d6678.Travel-Guide-Activities)[Car Rentals in Santee](https://expedia.com/Car-Rentals-In-Santee.d6678.Car-Rental-Guide)[Santee Vacation Packages](https://expedia.com/Santee.d6678.Destination-Travel-Guides)

![](https://images.trvl-media.com/place/3073/47ddac67-5969-41c0-8843-96304c5986bd.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/3073/47ddac67-5969-41c0-8843-96304c5986bd.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg)  
###  
Bundle & Save  
Get more, spend less whenever you see Bundle & Save deals
- ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg)  
###  
OneKeyCash  
Earn OneKeyCash on all your eligible bookings
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg)  
###  
Upfront pricing  
We are not like the others - we include taxes and fees

## Check prices for these dates

In two weeks

[Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 24 - Jul 26](https://www.expedia.com/Hotel-Search?regionId=6678&startDate=2026-07-24&endDate=2026-07-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santee vacation rentals

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/01804477.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/ae94e897.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 2 Bedrooms, Non Smoking | 1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/831e90be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Bedroom, Non Smoking | 1 bedroom, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/10000/4700/4694/b7ce7b36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Diego Country Estates

[](https://www.expedia.com/Ramona-Hotels-San-Diego-Country-Estates.h4694.Hotel-Information)

San Diego Country Estates

9.4/10

Exceptional

(265 reviews)

"Wonderful stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ARNAB

$118 nightly

$125 total

Apr 20 - Apr 21

Total with taxes and fees

[](https://www.expedia.com/Ramona-Hotels-San-Diego-Country-Estates.h4694.Hotel-Information)

![Rooftop terrace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/dd5fc603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/b4a5f1e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/6521c599.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/115000000/114120000/114116400/114116366/4123f91e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Sentral Gaslamp Quarter

[](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information)

Downtown San Diego

9.4/10

Exceptional

(813 reviews)

"Great location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ethan

$152 nightly

$176 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Sentral-Gaslamp-Quarter.h114116366.Hotel-Information)

![Beach nearby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/176e7c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/ae7c0c5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/31020b74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/850000/842000/841962/37bf8b39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Coronado Beach Resort

[](https://www.expedia.com/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information)

Historic Downtown Coronado

9.0/10

Wonderful

(780 reviews)

"Excellent location, clean and cozy"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Oksana

$229 nightly

$252 total

Apr 26 - Apr 27

Total with taxes and fees

[](https://www.expedia.com/Coronado-Hotels-Coronado-Beach-Resort.h841962.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/f34abdc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/97d1106b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/03c11edc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/1000000/20000/17900/17865/b715a864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott Vacation Club®, San Diego

[](https://www.expedia.com/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information)

Downtown San Diego

9.4/10

Exceptional

(1,049 reviews)

"The hotel was very clean and had very friendly staff. Location was amazing."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brenda

$169 nightly

$196 total

Apr 23 - Apr 24

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Marriott-Vacation-Club-Pulse.h17865.Hotel-Information)

![House | 3 bedrooms, desk, Internet](https://images.trvl-media.com/lodging/110000000/109410000/109406100/109406097/71646319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 3 bedrooms, desk, Internet](https://images.trvl-media.com/lodging/110000000/109410000/109406100/109406097/5551bcd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 3 bedrooms, desk, Internet](https://images.trvl-media.com/lodging/110000000/109410000/109406100/109406097/00ba5e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 3 bedrooms, desk, Internet](https://images.trvl-media.com/lodging/110000000/109410000/109406100/109406097/f6c8d36a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stunning View Mission Bay Luxury Home Private Pool

[](https://www.expedia.com/San-Diego-Hotels-Stunning-View-Mission-Bay-Luxury-Home-Private-Pool.h109406097.Hotel-Information)

Bay Park

$796 nightly

$898 total

Apr 12 - Apr 13

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Stunning-View-Mission-Bay-Luxury-Home-Private-Pool.h109406097.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/f291ebe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/c50c50bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Condo, 2 Bedrooms, Non Smoking, Kitchenette | Living area | Flat-screen TV, DVD player](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/c8678e64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/13000000/12780000/12774000/12773961/6177273a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wave Crest Resort

[](https://www.expedia.com/Del-Mar-Hotels-Wave-Crest-Resort.h12773961.Hotel-Information)

Del Mar

9.2/10

Wonderful

(151 reviews)

"Clean and convenient location."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jeffrey

$244 nightly

$271 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/Del-Mar-Hotels-Wave-Crest-Resort.h12773961.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/126000000/125670000/125669700/125669628/655e7f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/126000000/125670000/125669700/125669628/36e716a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/126000000/125670000/125669700/125669628/1e4b1aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi](https://images.trvl-media.com/lodging/126000000/125670000/125669700/125669628/f221b218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Large Group Wellness Retreat w Spa & Gym

[](https://www.expedia.com/San-Diego-Hotels-Large-Group-Wellness-Retreat-W-Spa-Gym.h125669628.Hotel-Information)

University City

$868 nightly

$978 total

Apr 22 - Apr 23

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Large-Group-Wellness-Retreat-W-Spa-Gym.h125669628.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/b278e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Room, 1 Queen Bed (East - Freeway Facing) | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/61427440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/e8d02919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Uptown Inn by Vantaggio - Limited Service Apart-Hotel

[](https://www.expedia.com/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information)

Hillcrest

8.4/10

Very Good

(328 reviews)

"It is a clean place to stay and budget friendly. Unfortunately the noise from the road can make it hard to sleep."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Afia

$117 nightly

$132 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information)

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/b28adcb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/cc51c6db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/8ecd0448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cottage (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/116000000/115490000/115486000/115485967/528a2b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Walk to La Jolla Cove: Dtwn Cottage w/ Ocean View!

[](https://www.expedia.com/La-Jolla-Hotels-Walk-To-La-Jolla-Cove-Dtwn-Cottage-W-Ocean-View.h115485967.Hotel-Information)

Village of La Jolla

$915 nightly

$1,028 total

Apr 14 - Apr 15

Total with taxes and fees

[](https://www.expedia.com/La-Jolla-Hotels-Walk-To-La-Jolla-Cove-Dtwn-Cottage-W-Ocean-View.h115485967.Hotel-Information)

![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6c7bbd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/333bf268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### City24 Hotel Little Italy Mission Hills

[](https://www.expedia.com/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information)

Middletown

9.6/10

Exceptional

(135 reviews)

"Clean nice place to stay at"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis

$161 nightly

$181 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/aa0ca94d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/96085407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 1 Queen Bed with Sofa bed, Bay View (Self Check-in with Virtual Front Desk) | Living area | 40-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/c58a022b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Bay View (QueenBed) (Self Check-in with Virtual Front Desk) | Balcony view](https://images.trvl-media.com/lodging/109000000/108780000/108772600/108772597/f6cadddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kasa Little Italy San Diego

[](https://www.expedia.com/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information)

Downtown San Diego

9.6/10

Exceptional

(400 reviews)

"Excellent location Clean Just as showed in pictures"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carina Jose

$260 nightly

$296 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Kasa-Little-Italy-San-Diego.h108772597.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/c1d43a1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full Bed Studio with Patio | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/87314e3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/36922b33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/115000000/114920000/114912200/114912134/401b2d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Little Italy Inn - Limited Service Apart Hotel

[](https://www.expedia.com/San-Diego-Hotels-Little-Italy-Inn.h114912134.Hotel-Information)

Downtown San Diego

8.4/10

Very Good

(117 reviews)

"Perfect stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kaylee

$114 nightly

$130 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Little-Italy-Inn.h114912134.Hotel-Information)

![Apartment | 1 bedroom, desk, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/4b1c7130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | 1 bedroom, desk, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/253b0ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | 1 bedroom, desk, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/f66a43de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment | 1 bedroom, desk, Internet](https://images.trvl-media.com/lodging/119000000/118270000/118267700/118267698/b3d698d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### NEW Upscale Downtown San Diego Stay Queen Bed Pool Sauna

[](https://www.expedia.com/San-Diego-Hotels-NEW-Upscale-Downtown-San-Diego-Stay-Queen-Bed-Pool-Sauna.h118267698.Hotel-Information)

Downtown San Diego

$379 nightly

$431 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-NEW-Upscale-Downtown-San-Diego-Stay-Queen-Bed-Pool-Sauna.h118267698.Hotel-Information)

![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Individually decorated, individually furnished, laptop workspace](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/834f95c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Suite, 1 Queen Bed (Self Check-in with Virtual Front Desk) | Living area | 40-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/f68e9f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/bc47b23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Studio, 1 Queen Bed (Self Check-in with Virtual Front Desk) | In-room dining](https://images.trvl-media.com/lodging/16000000/15690000/15682000/15681965/3636bd40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Kasa Gaslamp Quarter San Diego

[](https://www.expedia.com/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information)

Downtown San Diego

7.8/10

Good

(176 reviews)

"Clean room, air conditioning worked and security is great "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth

$109 nightly

$125 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/San-Diego-Hotels-Sonder-The-Marin.h15681965.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-18&endDate=2026-04-19&regionId=6678&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=VACATION_HOME)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=APARTMENT)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=CONDO)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=COTTAGE)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=VILLA)

Houseboats

[](https://www.expedia.com/Hotel-Search?destination=Santee%2C+California%2C+United+States+of+America&regionId=6678&latLong=32.838383%2C-116.973915&adults=2&startDate=2026-07-02&d1=2026-07-02&endDate=2026-07-05&d2=2026-07-05&lodging=HOUSE_BOAT)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Vacation-Rentals.d6678.Travel-Guide-VacationRentals)[

Sign up, it's free

](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantee-Vacation-Rentals.d6678.Travel-Guide-VacationRentals)

## Top Santee Hotel Reviews

![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/8cec183d_y.jpg)

### Handlery Hotel

10/10 Excellent

"Great staff nice rooms:) nice pool area "

[](https://expedia.com/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information)

![DoubleTree by Hilton San Diego - Del Mar](https://images.trvl-media.com/lodging/1000000/20000/15300/15236/aa48478b_y.jpg)

### DoubleTree by Hilton San Diego - Del Mar

8/10 Good

"There were many scrapes and stains in the room. Other than that the room was good."

[](https://expedia.com/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information)

![Wyndham San Diego Bayside](https://images.trvl-media.com/lodging/1000000/20000/11200/11177/a77f85c3_y.jpg)

### Wyndham San Diego Bayside

10/10 Excellent

"Clean room, Easy check in, check out process."

[](https://expedia.com/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information)

![California Suites Hotel](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg)

### California Suites Hotel

10/10 Excellent

"The property was beautiful- very well kept- felt tropical. Location was good- only 15 minutes from town. The front desk staff were very pleasant and helpful. Pool area was clean (not lots of deck chairs) Felt a little dated- but excellent value and the rooms were very clean with fridge, microwave and stove burners. Definitely would recommend and would stay there again in the future."

[](https://expedia.com/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information)

![Bay Club Hotel & Marina](https://images.trvl-media.com/lodging/1000000/10000/2600/2514/4003f7ef_y.jpg)

### Bay Club Hotel & Marina

6/10 Okay

"We booked a Bay View room and all we can see is a Palm Tree.... do not book room 209 unless you want to b just see a palm tree for extra money "

[](https://expedia.com/San-Diego-Hotels-Bay-Club-Hotel-Marina.h2514.Hotel-Information)

![Hotel del Coronado, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/7500/7496/w3840h2810x0y3-4edcf873_y.jpg)

### Hotel del Coronado, Curio Collection by Hilton

10/10 Excellent

"Clean hotel, great location and customer service. "

[](https://expedia.com/Coronado-Hotels-Hotel-Del-Coronado.h7496.Hotel-Information)

![Paradise Point Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3800/3731/d0f041ab_y.jpg)

### Paradise Point Resort & Spa

6/10 Okay

"The room did not meet expectations, especially considering the resort fee we were required to pay. Noise from neighboring rooms was quite noticeable, particularly in the early morning when we were trying to sleep in. I would have expected better soundproofing, as found in many other hotels, but that was not the case here. The room was also not very functional—there was only one chair, and the table was too small, making it uncomfortable to sit and eat. Additionally, the amenities felt lacking given the added cost of the resort fee. Overall, it was a disappointing experience for my family."

[](https://expedia.com/San-Diego-Hotels-Paradise-Point-Resort-Spa.h3731.Hotel-Information)

![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/bd726404_y.jpg)

### The Sofia Hotel

6/10 Okay

"Why is there a $17.65 amenities fee, when the front desk could not even explain what amenities was available. There were no complimentary water in the room, there were bottles of wine and coffee but no note whether these were a charge. Some toiletries were not replenish the second day. The street noise was quite audible. The room doors did not have a secondary latch for security."

[](https://expedia.com/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information)

![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg)

### Best Western Seven Seas

8/10 Good

"No breakfast "

[](https://expedia.com/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information)

## Find out more about Santee

**Everything you need to know about Santee vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santee vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $125 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santee rentals**

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Santee

### Trending destinations on Expedia.com

- [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals)
- [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals)
- [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals)
- [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals)
- [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)
- [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)
- [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)
- [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)
- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Santee ](https://expedia.com/Santee-Private-Vacation-Homes.d6678-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Apartments in Santee ](https://expedia.com/Santee-Apartments.d6678-aaApartments.Travel-Guide-Accommodation)
- [Condo Rentals in Santee ](https://expedia.com/Santee-Condos.d6678-aaCondos.Travel-Guide-Accommodation)
- [Cottages in Santee ](https://expedia.com/Santee-Cottages.d6678-aaCottages.Travel-Guide-Accommodation)
- [Villas in Santee ](https://expedia.com/Santee-Villas.d6678-aaVillas.Travel-Guide-Accommodation)
- [Resorts in Santee ](https://expedia.com/Santee-Resorts.d6678-aaResorts.Travel-Guide-Accommodation)
- [Guest Houses in Santee ](https://expedia.com/Santee-Guest-Houses.d6678-aaGuestHouses.Travel-Guide-Accommodation)
- [Aparthotels in Santee ](https://expedia.com/Santee-Apart-Hotels.d6678-aaApartHotels.Travel-Guide-Accommodation)
- [Motels in Santee ](https://expedia.com/Santee-Motels.d6678-aaMotels.Travel-Guide-Accommodation)
- [B&B in Santee ](https://expedia.com/Santee-Bed-And-Breakfast.d6678-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Hostels in Santee ](https://expedia.com/Santee-Hostels.d6678-aaHostels.Travel-Guide-Accommodation)
- [Cabin Rentals in Santee ](https://expedia.com/Santee-Cabins.d6678-aaCabins.Travel-Guide-Accommodation)
- [Farmstay in Santee ](https://expedia.com/Santee-Agritourism.d6678-aaAgritourism.Travel-Guide-Accommodation)
- [Lodges in Santee ](https://expedia.com/Santee-Lodges.d6678-aaLodges.Travel-Guide-Accommodation)
- [RV Parks in Santee ](https://expedia.com/Santee-RV-Parks.d6678-aaRVParks.Travel-Guide-Accommodation)
- [Houseboats in Santee ](https://expedia.com/Santee-Houseboats.d6678-aaHouseboats.Travel-Guide-Accommodation)
- [Inns in Santee ](https://expedia.com/Santee-Inns.d6678-aaInns.Travel-Guide-Accommodation)
- [Ranches in Santee ](https://expedia.com/Santee-Ranches.d6678-aaRanches.Travel-Guide-Accommodation)
- [Castles in Santee ](https://expedia.com/Santee-Castles.d6678-aaCastles.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find a vacation rental in Santee?

### What are some of the best vacation home rentals in Santee?

### How many vacation rentals are there in Santee?

### What’s there to see and do in Santee?

### What are vacation rentals like in Santee?

### Expedia's Latest Trends

Hotels

- [Hotels in Morro Bay](https://expedia.com/Morro-Bay-Hotels.d8976.Travel-Guide-Hotels)
- [Hotels in South Lake Tahoe](https://expedia.com/South-Lake-Tahoe-Hotels.d10150.Travel-Guide-Hotels)
- [Hotels in Carmel](https://expedia.com/Carmel-Hotels.d6026.Travel-Guide-Hotels)
- [Hotels in Oceanside](https://expedia.com/Oceanside-Hotels.d9154.Travel-Guide-Hotels)
- [Hotels in Newport Beach](https://expedia.com/Newport-Beach-Hotels.d8111.Travel-Guide-Hotels)
- [Hotels in Solvang](https://expedia.com/Solvang-Hotels.d9797.Travel-Guide-Hotels)
- [Hotels in Monterey](https://expedia.com/Monterey-Hotels.d180045.Travel-Guide-Hotels)
- [Hotels in Santa Cruz](https://expedia.com/Santa-Cruz-Hotels.d6666.Travel-Guide-Hotels)
- [Hotels in Sequoia National Park](https://expedia.com/Sequoia-National-Park-Hotels.d6084619.Travel-Guide-Hotels)
- [Hotels in Mammoth Lakes](https://expedia.com/Mammoth-Lakes-Hotels.d2363.Travel-Guide-Hotels)
- [Hotels in Huntington Beach](https://expedia.com/Huntington-Beach-Hotels.d8165.Travel-Guide-Hotels)
- [Hotels in Carlsbad](https://expedia.com/Carlsbad-Hotels.d6056550.Travel-Guide-Hotels)
- [Hotels in Anaheim](https://expedia.com/Anaheim-Hotels.d5921.Travel-Guide-Hotels)
- [Hotels in Temecula](https://expedia.com/Temecula-Hotels.d6034795.Travel-Guide-Hotels)
- [Hotels in Pismo Beach](https://expedia.com/Pismo-Beach-Hotels.d9118.Travel-Guide-Hotels)
- [Hotels in Irvine](https://expedia.com/Irvine-Hotels.d7819.Travel-Guide-Hotels)
- [Hotels in Palm Springs](https://expedia.com/Palm-Springs-Hotels.d180676.Travel-Guide-Hotels)
- [Hotels in Santa Barbara](https://expedia.com/Santa-Barbara-Hotels.d602277.Travel-Guide-Hotels)
- [Hotels in San Jose](https://expedia.com/San-Jose-Hotels.d602703.Travel-Guide-Hotels)
- [Hotels in San Luis Obispo](https://expedia.com/San-Luis-Obispo-Hotels.d6046822.Travel-Guide-Hotels)
- [Hotels in Big Bear Lake](https://expedia.com/Big-Bear-Lake-Hotels.d6919.Travel-Guide-Hotels)
- [Hotels in San Diego](https://expedia.com/San-Diego-Hotels.d3073.Travel-Guide-Hotels)

Flights

- [Cheap Flights to Anaheim](https://expedia.com/Cheap-Flights-To-Anaheim.d5921.Travel-Guide-Flights)
- [Cheap Flights to San Diego](https://expedia.com/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)
- [Cheap Flights to Palm Springs](https://expedia.com/Cheap-Flights-To-Palm-Springs.d180676.Travel-Guide-Flights)
- [Cheap Flights to San Jose](https://expedia.com/Cheap-Flights-To-San-Jose.d602703.Travel-Guide-Flights)

Cars

- [Car rentals in Palm Springs](https://expedia.com/Car-Rentals-In-Palm-Springs.d180676.Car-Rental-Guide)
- [Car rentals in San Jose](https://expedia.com/Car-Rentals-In-San-Jose.d602703.Car-Rental-Guide)
- [Car rentals in San Diego](https://expedia.com/Car-Rentals-In-San-Diego.d3073.Car-Rental-Guide)

Packages

- [San Diego Vacation](https://expedia.com/San-Diego.d3073.Destination-Travel-Guides)

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app