Santee Vacation Rentals

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  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Jun 5 - Jun 7
In two months
Jul 17 - Jul 19
In three months
Aug 14 - Aug 16
In four months
Sep 11 - Sep 13

Our top choices for Santee vacation rentals

Beach nearby, beach towels

Adorable 1 bedroom house 8 min from La Jolla!

Adorable 1 bedroom house 8 min from La Jolla!
Bay Ho
10.0 out of 10, Exceptional, (51 reviews)
"Sparkling clean, friendly host and thoughtful layout"
United States
Griff V.
$233 nightly
The price is $259
May 25 - May 26
Total with taxes and fees
Adorable 1 bedroom house 8 min from La Jolla!
Property grounds

Hilltop cabin with panoramic lake & mountain views

Hilltop cabin with panoramic lake & mountain views
Del Dios
9.6 out of 10, Exceptional, (33 reviews)
"Beautiful property, comfy cabin"
United States
Robert S.
$196 nightly
The price is $196
May 21 - May 22
Total with taxes and fees
Hilltop cabin with panoramic lake & mountain views
Terrace/patio

Private 2 bedroom apt in new craftsman ranch!

Private 2 bedroom apt in new craftsman ranch!
Escondido
10.0 out of 10, Exceptional, (19 reviews)
"We really enjoyed our stay! The amenities were great, the view and scenery were beautiful, and the property was very family-friendly. Would definitely recommend and stay again!"
United States
Joshua D.
$282 nightly
The price is $301
Jun 1 - Jun 2
Total with taxes and fees
Private 2 bedroom apt in new craftsman ranch!
Terrace/patio

Mini farm vibe stationary RV in No. San Diego County with WiFi, AC. TV. Views.

Mini farm vibe stationary RV in No. San Diego County with WiFi, AC. TV. Views.
West Ridge
9.4 out of 10, Exceptional, (13 reviews)
"Gorgoeus property and place to stay! Only surpassed by the amazing host, Diane. My favorite spot to stay in town and will continue to book regularly when available! "
United States
Zeyad A.
$118 nightly
The price is $118
May 21 - May 22
Total with taxes and fees
Mini farm vibe stationary RV in No. San Diego County with WiFi, AC. TV. Views.
Terrace/patio

Wine Country Cabin Near San Diego - on private 9 acres

Wine Country Cabin Near San Diego - on private 9 acres
Ramona
9.4 out of 10, Exceptional, (25 reviews)
" This is a great place to stay if you're looking for a quiet retreat. The setting is beautiful and private, which makes it a great weekend getaway. The only issue was that I couldn't get the TV to work. "
United States
Wendy S.
Wine Country Cabin Near San Diego - on private 9 acres
Terrace/patio

Cozy 2-Bedroom Cottage Near Balboa Park

Cozy 2-Bedroom Cottage Near Balboa Park
Mid-City
8.4 out of 10, Very Good, (8 reviews)
"This is such a charming cottage in San Diego! Loved our convenient stay and were close to everything that we needed. Thanks!"
United States
Ryne R.
$270 nightly
The price is $300
May 27 - May 28
Total with taxes and fees
Cozy 2-Bedroom Cottage Near Balboa Park
Terrace/patio

Breathtaking retreat in the wine country on the ranch with goats you can pet!

Breathtaking retreat in the wine country on the ranch with goats you can pet!
Escondido
10.0 out of 10, Exceptional, (16 reviews)
"The property was very clean and comfortable. The view was outstandinig."
United States
Earl
$341 nightly
The price is $341
May 26 - May 27
Total with taxes and fees
Breathtaking retreat in the wine country on the ranch with goats you can pet!
Outdoor spa tub

Private Resort "La Casita" Spa and Mini Golf Course

Private Resort "La Casita" Spa and Mini Golf Course
ALPINE
10.0 out of 10, Exceptional, (28 reviews)
"Awesome Ola Vibe of Magnificent Lush Property Oasis!!!"
United States
Marcy
$288 nightly
The price is $309
May 25 - May 26
Total with taxes and fees
Private Resort "La Casita" Spa and Mini Golf Course
Fridge, microwave, oven, stovetop

Beautiful Normal Heights Living

Beautiful Normal Heights Living
Mid-City
10.0 out of 10, Exceptional, (92 reviews)
"Great location, nice cozy place, had everything we needed. Would definitely stay again."
United States
Sheila S.
$286 nightly
The price is $318
May 25 - May 26
Total with taxes and fees
Beautiful Normal Heights Living
Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.8 out of 10, Exceptional, (151 reviews)
"Beautiful fully appointed rooms and excellent location."
United States
Michelle
$150 nightly
The price is $169
May 25 - May 26
Total with taxes and fees
City24 Hotel Little Italy Mission Hills
1 bedroom, desk, iron/ironing board, free WiFi

Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!

Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!
La Costa
10.0 out of 10, Exceptional, (68 reviews)
"Great location comfy beds will definitely book again"
United States
Valerie E.
$307 nightly
The price is $340
May 21 - May 22
Total with taxes and fees
Luxurious La Costa Remodel by SPA w/Steam Shower and Washer/Dryer!
Property grounds

Unique Adobe Sanctuary w/hot tub close to hiking trails & wineries

Unique Adobe Sanctuary w/hot tub close to hiking trails & wineries
San Marcos
10.0 out of 10, Exceptional, (3 reviews)
"It was everything and more, the host was super polite and everything was clean. The hot tub was to die for and I probably got the best sleep I did in a while!! Will come back again "
United States
Sofia C.
$415 nightly
The price is $415
May 21 - May 22
Total with taxes and fees
Unique Adobe Sanctuary w/hot tub close to hiking trails & wineries
1 bedroom, iron/ironing board, WiFi, bed sheets

Cozy Private Studio in El Cajon

Cozy Private Studio in El Cajon
Mount Helix
8.6 out of 10, Excellent, (22 reviews)
"Very clean and comfortable. "
United States
Erik
$97 nightly
The price is $97
May 26 - May 27
Total with taxes and fees
Cozy Private Studio in El Cajon
Property grounds

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay

Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Old Town San Diego
10.0 out of 10, Exceptional, (281 reviews)
"We enjoyed our time in the back cottage. Everything we needed was available. We were able to just walk to so many sites and restaurants. Will definitely try to come back again! "
United States
Phillip
$207 nightly
The price is $230
May 26 - May 27
Total with taxes and fees
Adorable 1 bd cottage, heart of Old Town-- WE LOVE PETS! Insta @oldtownvacay
Fridge, microwave, oven, stovetop

Bright Cozy 3b/2b with nice backyard & BBQ

Bright Cozy 3b/2b with nice backyard & BBQ
Mira Mesa
10.0 out of 10, Exceptional, (21 reviews)
"This house is beautiful clean beautiful kitchen and make you feel home I will comeback thank you!!"
United States
Brianna
$448 nightly
The price is $499
May 21 - May 22
Total with taxes and fees
Bright Cozy 3b/2b with nice backyard & BBQ
Lobby sitting area

Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Uptown Inn by Vantaggio - Limited Service Apart-Hotel
2.5 star property
Hillcrest
8.4 out of 10, Very Good, (365 reviews)
"The hotel was clean and staff was very nice. I would stay here again."
United States
Cenaida
$104 nightly
The price is $117
May 25 - May 26
Total with taxes and fees
Uptown Inn by Vantaggio - Limited Service Apart-Hotel
Smart TV, fireplace, books, music library

Beautiful, Charming, Historic 2BR Cottage-Yard/Patio-Blocks To Beaches/Shops-OB

Beautiful, Charming, Historic 2BR Cottage-Yard/Patio-Blocks To Beaches/Shops-OB
Ocean Beach
9.6 out of 10, Exceptional, (15 reviews)
"Wonderful place to stay!"
United States
Tammie M.
$353 nightly
The price is $393
May 25 - May 26
Total with taxes and fees
Beautiful, Charming, Historic 2BR Cottage-Yard/Patio-Blocks To Beaches/Shops-OB
Smart TV, books

Lake San Marcos Gem. Walking Distance to Lake, Dining and Golf!

Lake San Marcos Gem. Walking Distance to Lake, Dining and Golf!
San Marcos
9.6 out of 10, Exceptional, (23 reviews)
"Everything was great! Thanks for having us."
United States
Dan H.
$441 nightly
The price is $473
May 21 - May 22
Total with taxes and fees
Lake San Marcos Gem. Walking Distance to Lake, Dining and Golf!
Smart TV, foosball, books, stereo

Villa Amarone - San Diego - Location, Hilltop View, Hot Tub, Pet friendly

Villa Amarone - San Diego - Location, Hilltop View, Hot Tub, Pet friendly
Bonita
10.0 out of 10, Exceptional, (24 reviews)
"Great property and view. Loved it"
United States
Lyla G.
$752 nightly
The price is $818
May 26 - May 27
Total with taxes and fees
Villa Amarone - San Diego - Location, Hilltop View, Hot Tub, Pet friendly
Terrace/patio

Vintage Airstream Trailer in the Hills of San Marcos!

Vintage Airstream Trailer in the Hills of San Marcos!
San Marcos
9.8 out of 10, Exceptional, (37 reviews)
"Very comfy great experience will definitely go again "
United States
Stephanie F.
$232 nightly
The price is $232
May 28 - May 29
Total with taxes and fees
Vintage Airstream Trailer in the Hills of San Marcos!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

The Dana on Mission Bay

The Dana on Mission Bay

10/10 Excellent
"Perfect little get away! Close to zoo as well As beach and nice spot on the marina. Paul the bartender at the pool bar was top notch! Lanai room was just great for our family get away. "
Mary 4-night trip
Posted 4 hours ago
The Dana on Mission Bay

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $116 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Santee?

Yes, there are vacation rentals where you'll be just 12.5 mi (20.1 km) from San Diego Zoo, giving you a more secluded option if you want a quieter place to stay. The shops and restaurants are several reasons why visitors like Santee. While you're here, grab a bite or have a drink at the bars.

What are some of the best vacation home rentals in Santee?

3 Story Spanish Style House, Best Location in SD. Views of North Park, With AC: Visitors like this Santee vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals are there in Santee?

Expedia has 5 vacation rentals for your stay in Santee.

What’s there to see and do in Santee?

Cultural attractions include Off Broadway Live and Creation and Earth History Museum, whereas Sportsplex USA Santee and Santee Lakes are a couple of picturesque spots to enjoy the outdoors. San Diego Zoo and Mission Bay are other popular places to visit in the area.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can stay in for several days or longer in Santee. Vacation rentals feature extras such as WiFi and washers and dryers so you'll be comfy for your stay. If you're concerned about cleanliness, a vacation rental can offer a sense of security away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular choice for families.