Santee Vacation Rentals

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Our top choices for Santee vacation rentals

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Santee
10.0 out of 10, Exceptional, (38 reviews)
"Great house, very modern interior. Very clean. Close to town. We’ll definitely book the house on our fishing trip. "
United States
John H.
$301 nightly
The price is $334
Mar 4 - Mar 5
Total with taxes and fees
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Tranquil Getaways W/Heated Pool and Fishing

Tranquil Getaways W/Heated Pool and Fishing
Elloree
8.4 out of 10, Very Good, (6 reviews)
"Great property the pool was so fun! Mostly stayed on the property and lounged around for a nice relaxing stay!"
United States
Tori P.
$179 nightly
The price is $199
Feb 18 - Feb 19
Total with taxes and fees
Tranquil Getaways W/Heated Pool and Fishing

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!
Santee
10.0 out of 10, Exceptional, (11 reviews)
"Annual golf trip with old friends. Perfect accommodations & location. Hope to stay again"
United States
Greg M.
$460 nightly
The price is $511
Feb 23 - Feb 24
Total with taxes and fees
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Country living lake style near Santee

Country living lake style near Santee
Summerton
10.0 out of 10, Exceptional, (42 reviews)
"Great stay."
United States
Tim E.
$192 nightly
The price is $213
Feb 15 - Feb 16
Total with taxes and fees
Country living lake style near Santee

Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (22 reviews)
"Enjoyed the stay. Out in the country, Great!"
United States
Marty D.
$150 nightly
The price is $167
Feb 22 - Feb 23
Total with taxes and fees
Country Resting Spot just off I95. 12 miles west on hwy 6.

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
Summerton
9.2 out of 10, Wonderful, (20 reviews)
"Great stay!! "
United States
Josh L.
$162 nightly
The price is $180
Mar 2 - Mar 3
Total with taxes and fees
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton

Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton
Summerton
$249 nightly
The price is $276
Mar 8 - Mar 9
Total with taxes and fees
Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.2 out of 10, Very Good, (14 reviews)
"We enjoyed our stay. The only negative would be the fishing pier is no longer useable. "
United States
Derrick W.
$120 nightly
The price is $133
Feb 15 - Feb 16
Total with taxes and fees
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (132 reviews)
"This cottage is always perfect! Just the right size & beautiful! The amenities & little touches made us feel at home immediately. "
United States
Phyllis R.
Pet friendly country cottage with large fenced-in yard & horses on property

Cabin at the lake in Rimini, SC

Cabin at the lake in Rimini, SC
Rimini
7.8 out of 10, Good, (7 reviews)
"Great view, excellent communication with the owners, relaxing, peaceful. "
United States
Christie
$128 nightly
The price is $142
Feb 16 - Feb 17
Total with taxes and fees
Cabin at the lake in Rimini, SC

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (87 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
$105 nightly
The price is $116
Feb 17 - Feb 18
Total with taxes and fees
Bells Marina & Resort

Private Farm Stay on 30-Acres

Private Farm Stay on 30-Acres
Summerton
$407 nightly
The price is $452
Feb 15 - Feb 16
Total with taxes and fees
Private Farm Stay on 30-Acres

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston
Holly Hill
10.0 out of 10, Exceptional, (7 reviews)
"Wonderful stay"
United States
Christina S.
$145 nightly
The price is $161
Feb 15 - Feb 16
Total with taxes and fees
Charming 2-bedroom cottage close to I26 and I95; 1 hr from Charleston

The Tee Vee Cove is the place to be located near great golfing, fishing and food

The Tee Vee Cove is the place to be located near great golfing, fishing and food
Elloree
$237 nightly
The price is $263
Feb 20 - Feb 21
Total with taxes and fees
The Tee Vee Cove is the place to be located near great golfing, fishing and food

Modern apartment overlooking historic downtown Elloree, SC.

Modern apartment overlooking historic downtown Elloree, SC.
Elloree
$119 nightly
The price is $132
Feb 19 - Feb 20
Total with taxes and fees
Modern apartment overlooking historic downtown Elloree, SC.

Sweet Marion - Dock + Boat Ramp + Hot Tub!

Sweet Marion - Dock + Boat Ramp + Hot Tub!
Summerton
8.6 out of 10, Excellent, (18 reviews)
"Nice comfortable place to stay"
United States
Dylan H.
$414 nightly
The price is $470
Feb 17 - Feb 18
Total with taxes and fees
Sweet Marion - Dock + Boat Ramp + Hot Tub!

Boat House (private Cabin) - Boat House (Private Cabin)

Boat House (private Cabin) - Boat House (Private Cabin)
Eutawville
10.0 out of 10, Exceptional, (1 review)
"This was a 1-night stop over for us, on the way to Florida. Unfortunately, we only had saltwater poles, or we would have loved to try our luck at fishing the lake. Fish were popping the water everywhere. We really enjoyed watching the gators cruising the lake as well! 1st for us. This was just a simple, no frills campground, but would love to ho back one day. Lodge was clean, and enjoyed sitting on the quiet back deck."
United States
Jaime W.
$246 nightly
The price is $273
Feb 26 - Feb 27
Total with taxes and fees
Boat House (private Cabin) - Boat House (Private Cabin)

Turtle Cove - Lake Living on Lake Marion

Turtle Cove - Lake Living on Lake Marion
Summerton
$375 nightly
The price is $426
Feb 22 - Feb 23
Total with taxes and fees
Turtle Cove - Lake Living on Lake Marion

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Blue Bird Manor 3-bedroom house located in the heart of Orangeburg
Orangeburg
$196 nightly
The price is $222
Feb 15 - Feb 16
Total with taxes and fees
Blue Bird Manor 3-bedroom house located in the heart of Orangeburg

Beautiful brick home w/ large porch and 3 bedrooms

Beautiful brick home w/ large porch and 3 bedrooms
Bowman
9.0 out of 10, Wonderful, (4 reviews)
"Nice and quiet property. It served us well for the weekend "
United States
Mick S.
$253 nightly
The price is $280
Feb 18 - Feb 19
Total with taxes and fees
Beautiful brick home w/ large porch and 3 bedrooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Santee Hotel Reviews

Find out more about Santee

Everything you need to know about Santee vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santee vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santee vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santee in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $116 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find vacation rentals in Santee?

Yes, we offer vacation rentals near the most popular points of interest in Santee, or you can select a more remote option if you'd like a relaxing place to stay. Tourists appreciate the top-notch restaurants and coffeehouses in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best vacation home rentals in Santee?

Wyndham Vacation Resorts Lake Marion: This highly rated vacation home rental in Santee is equipped with an outdoor pool, free WiFi, and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher, and a stovetop. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many vacation rentals are there in Santee?

Expedia has 7 vacation rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Santee National Wildlife Refuge are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are vacation rentals like in Santee?

Vacation rentals are private accommodations you can book for several days or more in Santee. Vacation rentals feature amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and bustling concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great choice for family gatherings.